Collated Gene Ontology terms

Biological process: NADH pyrophosphatase activity(2010, 2024, 2025) ADP-ribose diphosphatase activity(2005, 2009, 2017, 2025) NAD binding(2006, 2017, 2025) hydrolase activity(2025) metal ion binding(2025) FAD diphosphatase activity(2025) NAD+ diphosphatase activity(2009, 2025) pyrophosphatase activity(2025) nucleoside diphosphate phosphatase activity(2008) ADP-ribose pyrophosphohydrolase activity(2015)
ADP-glucose pyrophosphohydrolase activity2012

Molecular function: negative regulation of cell population proliferation2022, 2025 negative regulation of cell cycle2018, 2025 response to oxidative stress2006, 2008 transcription elongation by RNA polymerase II2025 response to wounding2009 response to salt stress2006 response to ozone2006 response to other organism2006 regulation of starch biosynthetic process2012 protein poly-ADP-ribosylation2009
positive regulation of salicylic acid mediated signaling pathway2010 plant-type hypersensitive response2006 innate immune response-activating signaling pathway2020 defense response to bacterium2007 cellular response to hypoxia2019

Cellular component: mitochondrion2024, 2025 cytoplasm2012, 2018, 2025 nucleus2012, 2018, 2025 cytosol2018, 2019 plasma membrane2012, 2025 chloroplast2018 elongin complex2025

Phylogenetic distribution

Chordates: 19/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 0/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 1/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 40/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 5 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
A0A8V0XG24_CHICK
Ensembl»
1.5
Nucleoside diphosphate-linked moiety X motif
6 (Nudix motif 6) (EC 3.6.1.-)		 Gallus gallus
TI:9031 None
   
Q9SJC5_ARATH
TAIR»
0.0
At2g04440 Nudix hydrolase (AtNUDT) (EC 3.6.1.13)
(EC 3.6.1.22) (ADP-ribose pyrophosphatase) (NADH pyrophosphatase)		 Arabidopsis thaliana
TI:3702 None
 
Q54U83_DICDI
dictyBase»
1.5
DDB_G0281219 Nucleoside diphosphate-linked moiety X motif 6 Dictyostelium discoideum
TI:44689 None
 
Q54L59_DICDI
dictyBase»
1.5
DDB_G0286883 NUDIX hydrolase family protein Dictyostelium discoideum
TI:44689 None
 
Q54FR0_DICDI
dictyBase»
1.5
DDB_G0290689 NUDIX hydrolase family protein Dictyostelium discoideum
TI:44689 None
 
Q9VXR9_DROME
FlyBase»
2.0
Dmel\CG8128 FI03680p (Uncharacterized protein, isoform A) (Uncharacterized protein,
isoform B (EC 3.-.-.-, EC 3.6.1.13, EC 3.6.1.22))		 Drosophila melanogaster
TI:7227 None
 
NUD10_ARATH
TAIR»
3.1
NUDT10 Nudix hydrolase 10 (AtNUDT10) (EC 3.6.1.-) (ADP-ribose
pyrophosphatase) (EC 3.6.1.13) (NADH pyrophosphatase) (EC 3.6.1.22)		 Arabidopsis thaliana
TI:3702 None
 
NUDT2_ARATH
TAIR»
3.9
NUDT2 Nudix hydrolase 2 (AtNUDT2) (EC 3.6.1.-) (ADP-ribose
pyrophosphatase) (EC 3.6.1.13) (NADH pyrophosphatase) (EC 3.6.1.22)		 Arabidopsis thaliana
TI:3702 None
 
NUDT5_ARATH
TAIR»
1.5
NUDT5 Nudix hydrolase 5 (AtNUDT5) (EC 3.6.1.-) Arabidopsis thaliana
TI:3702 None
 
NUDT6_ARATH
TAIR»
5.5
NUDT6 Nudix hydrolase 6 (AtNUDT6) (EC 3.6.1.-) (ADP-ribose
pyrophosphatase) (EC 3.6.1.13) (NADH pyrophosphatase) (EC 3.6.1.22)		 Arabidopsis thaliana
TI:3702 None
 
NUDT6_HUMAN
Ensembl»
4.7
NUDT6 Nudix hydrolase 6 (Antisense basic fibroblast growth factor) (FAD diphosphatase NUDT6) (EC 3.6.1.18) (NADH
pyrophosphatase NUDT6) (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 6) (Nudix motif 6) (Protein GFG)		 Homo sapiens
TI:9606 None
 
NUDT7_ARATH
TAIR»
13.2
NUDT7 Nudix hydrolase 7 (AtNUDT7) (EC 3.6.1.-) (ADP-ribose pyrophosphatase) (EC
3.6.1.13) (NADH pyrophosphatase) (EC 3.6.1.22) (Protein GROWTH FACTOR GENE 1)		 Arabidopsis thaliana
TI:3702 None
 
NUDT8_ARATH
TAIR»
2.3
NUDT8 Nudix hydrolase 8 (AtNUDT8) (EC 3.6.1.-) Arabidopsis thaliana
TI:3702 None
 
NUDT6_MOUSE
Ensembl»
4.5
Nudt6 Nudix hydrolase 6 (Antisense basic fibroblast growth factor B) (FAD diphosphatase NUDT6) (EC 3.6.1.18)
(NADH pyrophosphatase NUDT6) (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 6) (Nudix motif 6)		 Mus musculus
TI:10090 None
 
NUDT6_RAT
RGD»
4.5
Nudt6 Nudix hydrolase 6 (FAD diphosphatase NUDT6) (EC 3.6.1.18) (NADH pyrophosphatase NUDT6) (EC
3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 6) (Nudix motif 6) (Protein GFG)		 Rattus norvegicus
TI:10116 None
 
A3KNL9_DANRE
ZFIN»
1.5
nudt6 Nucleoside diphosphate-linked moiety X motif
6 (Nudix motif 6) (EC 3.6.1.-)		 Danio rerio
TI:7955 None