Collated Gene Ontology terms

Biological process: enzyme activator activity(2022, 2023, 2025) methyltransferase activity(2025) transferase activity(2025) tRNA methyltransferase activator activity(2025) RNA nuclease activity(2025)

Molecular function: tRNA modification2011, 2017, 2025 RNA (guanine-N7)-methylation2025 tRNA processing2025 tRNA (guanine-N7)-methylation2017, 2018, 2023, 2025 DNA damage response2025 methylation2025 tRNA methylation2025 spermatogenesis2007, 2025 oogenesis2007, 2025 tRNA stabilization2025
response to oxidative stress2025 cell differentiation2025 7-methylguanosine metabolic process2011

Cellular component: nucleus2009, 2013, 2017, 2018, 2025 tRNA methyltransferase complex2017, 2025 cytosol2009, 2017, 2025 tRNA (m7G46) methyltransferase complex2018, 2019, 2023, 2024, 2025 nucleoplasm2007, 2015, 2024, 2025 nuclear lumen2017, 2025 cytoplasm2018, 2025 chromosome2025 male germ cell nucleus2009 female germ cell nucleus2009

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 3/4 
Harosa: 3/4 
Hacrobia: 0/0 
Plants: 38/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
Q93WD7_ARATH
TAIR»
2.1
TRM82 tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit
(WD repeat-containing protein 4 homolog)		 Arabidopsis thaliana
TI:3702 None
 
TRM82_YEAST
SGD»
4.5
TRM82 tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit
TRM82 (Transfer RNA methyltransferase 82)		 Saccharomyces cerevisiae
TI:4932 None
 
A0A8V0Y3X8_CHICK
Ensembl»
0.5
WDR4 WD repeat domain 4 Gallus gallus
TI:9031 None
   
WDR4_HUMAN
Ensembl»
2.9
WDR4 tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 (Protein
Wuho homolog) (hWH) (WD repeat-containing protein 4)		 Homo sapiens
TI:9606 None
 
D4A0Q3_RAT
RGD»
2.0
Wdr4 WD repeat domain 4 Rattus norvegicus
TI:10116 None
   
WDR4_MOUSE
AG»
4.5
Wdr4 tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 (Protein
Wuho homolog) (mWH) (WD repeat-containing protein 4)		 Mus musculus
TI:10090 None
 
TRM82_SCHPO
PomBase»
1.0
trm82 tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit
trm82 (Transfer RNA methyltransferase 82)		 Schizosaccharomyces pombe
TI:4896 None
 
WDR4_CAEEL
WormBase»
0.5
wdr-4 tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit
(WD repeat-containing protein 4 homolog)		 Caenorhabditis elegans
TI:6239 None
 
WDR4_DANRE
ZFIN»
2.0
wdr4 tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit
wdr4 (WD repeat-containing protein 4)		 Danio rerio
TI:7955 None
 
WDR4_DICDI
dictyBase»
0.5
wdr4 tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit
wdr4 (WD repeat-containing protein 4)		 Dictyostelium discoideum
TI:44689 None
 
WUHO_DROME
FlyBase»
2.1
wuho tRNA (guanine-N(7)-)-methyltransferase non-catalytic
subunit wuho (protein wuho)		 Drosophila melanogaster
TI:7227 None