Collated Gene Ontology terms

Biological process: membrane insertase activity(2020, 2022, 2025) protein-folding chaperone binding(2020, 2025)

Molecular function: tail-anchored membrane protein insertion into ER membrane2020, 2022, 2024, 2025 protein insertion into ER membrane by stop-transfer membrane-anchor sequence2020, 2024, 2025 protein folding in endoplasmic reticulum2019, 2025 phospholipid transport2024, 2025 phospholipid metabolic process2024, 2025 wound healing2019 rhodopsin biosynthetic process2015 rhabdomere development2015 retina development in camera-type eye2008 photoreceptor cell maintenance2008

Cellular component: EMC complex2012, 2020, 2024, 2025 membrane2012, 2025 endoplasmic reticulum membrane2020, 2024, 2025 endoplasmic reticulum2015, 2018, 2021, 2025 trans-Golgi network transport vesicle2005, 2025 Golgi apparatus2005, 2025 mitochondrion2021 endomembrane system2014 cytosol2009 cytoplasm2025

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 15/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 2/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 38/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
Q9SU27_ARATH
TAIR»
1.0
At4g12590 ER membrane protein complex subunit 3 Arabidopsis thaliana
TI:3702 None
 
Q9U1X6_CAEEL
WormBase»
1.0
emc-3 ER membrane protein complex subunit 3 Caenorhabditis elegans
TI:6239 None
 
B0V1B5_DANRE
ZFIN»
1.0
zgc:86609 ER membrane protein complex subunit 3 Danio rerio
TI:7955 None
 
EMC3_DANRE
ZFIN»
4.1
emc3 ER membrane protein complex subunit
3 (Protein pob) (Transmembrane protein 111)		 Danio rerio
TI:7955 None
 
EMC3_DICDI
dictyBase»
2.5
emc3 ER membrane protein complex
subunit 3 (Transmembrane protein 111)		 Dictyostelium discoideum
TI:44689 None
 
Q9VKR0_DROME
FlyBase»
5.9
EMC3 ER membrane protein complex subunit 3 Drosophila melanogaster
TI:7227 None
 
E1BQV4_CHICK
Ensembl»
1.0
EMC3 ER membrane protein complex subunit 3 Gallus gallus
TI:9031 None
   
EMC3_HUMAN
Ensembl»
4.2
EMC3 ER membrane protein complex
subunit 3 (Transmembrane protein 111)		 Homo sapiens
TI:9606 None
 
EMC3_MOUSE
Ensembl»
4.0
Emc3 ER membrane protein complex
subunit 3 (Transmembrane protein 111)		 Mus musculus
TI:10090 None
 
EMC3_RAT
RGD»
4.0
Emc3 ER membrane protein complex
subunit 3 (Transmembrane protein 111)		 Rattus norvegicus
TI:10116 None
 
EMC3_YEAST
SGD»
5.5
EMC3 ER membrane protein complex subunit 3
(Altered inheritance rate of mitochondria protein 27)		 Saccharomyces cerevisiae
TI:4932 None
 
YNY3_SCHPO
PomBase»
1.8
SPBC1711.03 ER membrane protein complex subunit 3 Schizosaccharomyces pombe
TI:4896 None