Unknome v3

Cluster UKP04539
TRANSFORMING GROWTH FACTOR BETA REGULATED GENE 1
Standard knownness: 5.5; Custom knownness: None; Num. species: 67; Orthology database: Panther19.0; Protein members: 101

Collated Gene Ontology terms

Biological process: histone modifying activity⁽²⁰²⁵⁾ DNA binding⁽²⁰²⁵⁾ ubiquitin-protein transferase activity⁽²⁰²⁵⁾ oxidoreductase activity⁽²⁰²⁵⁾ metal ion binding⁽²⁰²⁵⁾ histone H3K4 demethylase activity⁽²⁰²⁵⁾ dioxygenase activity⁽²⁰²⁵⁾ ATP binding⁽²⁰²⁵⁾

Molecular function: regulation of cell cycle^{2021, 2025} chromatin remodeling²⁰²⁵ system development²⁰²⁵ protein stabilization^{2007, 2025} protein localization to nucleoplasm^{2017, 2025} negative regulation of cell population proliferation^{2007, 2025} DNA replication^{2007, 2025} regulation of DNA-templated transcription²⁰²⁵ DNA-templated transcription²⁰²⁵ protein ubiquitination²⁰²⁵
negative regulation of gene expression, epigenetic²⁰²⁵ negative regulation of developmental process²⁰²⁵ developmental growth²⁰²⁵ chromatin organization²⁰²⁵

Cellular component: nucleus^{2007, 2018, 2021, 2025} nucleoplasm^{2024, 2025}

Phylogenetic distribution

Chordates:	19/21
Echinoderms:	0/0
Hemichordates:	1/1
Annelids:	1/1
Molluscs:	0/0
Bryozoans:	0/0
Platyhelminthes:	0/0
Rotifers:	0/0
Nematodes:	0/3
Arthropods:	4/5
Tardigrades:	0/0
Placozoa:	1/1
Cnidaria:	1/1
Porifera:	0/0
Choanoflagellates+:	1/1
Dikarya:	0/14
Fungi (other):	0/1
Protozoa:	0/3
Excavates:	1/4
Harosa:	1/4
Hacrobia:	0/0
Plants:	37/39
Archea:	0/8
Bacteria:	0/35

Cluster UKP04539

Collated Gene Ontology terms

Phylogenetic distribution

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Knownness history

Proteins