Collated Gene Ontology terms

Biological process: oxidoreductase activity(2012, 2024) D-amino-acid dehydrogenase activity(2011, 2015, 2017, 2019, 2024) tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity(2011, 2017, 2024) metal ion binding(2024) flavin adenine dinucleotide binding(2024) 2 iron, 2 sulfur cluster binding(2024) iron-sulfur cluster binding(2024) sarcosine dehydrogenase activity(2017, 2024) oxidoreductase activity, acting on the CH-NH group of donors(2024) methyltransferase activity(2024)
S-adenosylmethionine-dependent methyltransferase activity2024 sarcosine oxidase activity2016, 2019, 2024 FAD binding2011, 2017, 2023 D-amino-acid oxidase activity2023, 2024 glycine oxidase activity2017, 2024 dimethylglycine dehydrogenase activity2017 L-amino-acid oxidase activity2024 nucleotide binding2024 protein homodimerization activity2021 proline dehydrogenase activity2016 potassium ion transmembrane transporter activity2024 identical protein binding2019 glycine dehydrogenase (cyanide-forming) activity2024 glycerol-3-phosphate dehydrogenase (quinone) activity2024 calcium-dependent protein serine/threonine phosphatase regulator activity2024 NADH dehydrogenase activity2019 D-aspartate oxidase activity2024 2-hydroxyglutarate dehydrogenase activity2024

Molecular function: mitochondrial respiratory chain complex I assembly2015, 2017, 2024 retrograde transport, endosome to Golgi2013, 2017, 2024 D-alanine catabolic process2017, 2021, 2024 sarcosine catabolic process2014, 2017, 2019, 2024 D-amino acid catabolic process2023, 2024 tRNA processing2024 methylation2024 thiamine diphosphate biosynthetic process2024 tRNA wobble uridine modification2013, 2017 tRNA wobble base modification2024
thiamine biosynthetic process2017, 2024 putrescine catabolic process2021, 2024 arginine metabolic process2015 arginine catabolic process2015 transcription elongation by RNA polymerase II2021 tetrahydrofolate metabolic process2024 tRNA methylation2011 response to herbicide2024 potassium ion transport2024 potassium ion transmembrane transport2024 polyamine catabolic process2019 phosphate-containing compound metabolic process2024 organophosphate metabolic process2024 nitrogen utilization2024 glycerol-3-phosphate metabolic process2024 glycerol catabolic process2024 chromatin remodeling2021 amino acid metabolic process2017 S-adenosylmethionine cycle2014 L-alanine oxidation to pyruvate via D-alanine2021 4-hydroxyproline catabolic process2019

Cellular component: cytoplasm2013, 2017, 2023, 2024 mitochondrion2009, 2014, 2021, 2023, 2024 mitochondrial matrix2013, 2017, 2024 membrane2024 late endosome2013, 2017, 2024 plasma membrane2011, 2017, 2024 mitochondrial inner membrane2015, 2024 cytosol2009, 2024 extracellular region2024 mitochondrial outer membrane2015
sarcosine oxidase complex2016 respiratory chain complex I2015 pyruvate dehydrogenase complex2024 pyruvate dehydrogenase (lipoamide) phosphatase complex2021 peptidoglycan-based cell wall2023 oxidoreductase complex2019 endosome2024 NADH dehydrogenase complex2019

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 2/4 
Harosa: 3/4 
Hacrobia: 0/0 
Plants: 37/39 
Archea: 6/8 
Bacteria: 27/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
MNMC_ECOLI
EnsemblBacteria»
4.2
mnmC tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC (tRNA mnm(5)s(2)U biosynthesis bifunctional
protein) [Includes: tRNA (mnm(5)s(2)U34)-methyltransferase (EC 2.1.1.61); FAD-dependent cmnm(5)s(2)U34 oxidoreductase (EC 1.5.-.-)]		 Escherichia coli
TI:562 None
 
DADA_ECOLI
EnsemblBacteria»
4.2
dadA D-amino acid dehydrogenase
(EC 1.4.99.-) (D-alanine dehydrogenase)		 Escherichia coli
TI:562 None
 
TDA3_YEAST
SGD»
2.9
TDA3 Putative oxidoreductase TDA3 (EC 1.-.-.-) (Batten disease
protein 3) (Topoisomerase I damage affected protein 3)		 Saccharomyces cerevisiae
TI:4932 None
 
A1ZAZ2_DROME
FlyBase»
3.1
Sardh Sarcosine dehydrogenase (EC 1.-.-.-, EC 1.5.8.3) Drosophila melanogaster
TI:7227 None
 
FXRD1_HUMAN
Ensembl»
1.3
FOXRED1 FAD-dependent oxidoreductase domain-containing
protein 1 (EC 1.-.-.-)		 Homo sapiens
TI:9606 None
 
PDPR_HUMAN
Ensembl»
0.0
PDPR Pyruvate dehydrogenase phosphatase
regulatory subunit, mitochondrial (PDPr)		 Homo sapiens
TI:9606 None
 
D3ZEH2_RAT
RGD»
1.0
Foxred1 FAD-dependent oxidoreductase domain containing 1 Rattus norvegicus
TI:10116 None
   
FXRD1_MOUSE
Ensembl»
0.5
Foxred1 FAD-dependent oxidoreductase domain-containing
protein 1 (EC 1.-.-.-)		 Mus musculus
TI:10090 None
 
YAM3_SCHPO
PomBase»
0.5
SPAC1F5.03c Putative oxidoreductase C1F5.03c (EC 1.-.-.-) Schizosaccharomyces pombe
TI:4896 None
 
YE66_SCHPO
PomBase»
0.5
SPAC6G10.06 Putative oxidoreductase C6G10.06 (EC 1.-.-.-) Schizosaccharomyces pombe
TI:4896 None
 
PUUB_ECOLI
EnsemblBacteria»
1.6
puuB Gamma-glutamylputrescine oxidoreductase (Gamma-Glu-Put oxidase)
(Gamma-glutamylputrescine oxidase) (EC 1.4.3.-)		 Escherichia coli
TI:562 None
 
A0A486WWC6_CAEEL
WormBase»
0.5
CELE_Y37E3.17 Y37E3.17 Dimethylglycine dehydrogenase, mitochondrial Caenorhabditis elegans
TI:6239 None
 
A1Z6N5_DROME
FlyBase»
0.5
Dmel\CG3270 FI13301p Drosophila melanogaster
TI:7227 None
 
Q9VJ10_DROME
FlyBase»
0.5
l(2)37Bb Lethal (2) 37Bb (EC 1.-.-.-) (RE18450p) Drosophila melanogaster
TI:7227 None
 
A0A8I5ZQQ3_RAT
RGD»
0.0
Pdpr Pyruvate dehydrogenase
phosphatase regulatory subunit		 Rattus norvegicus
TI:10116 None
   
A8WG78_DANRE
ZFIN»
0.5
foxred1 FAD-dependent oxidoreductase domain-containing protein
1 (Zgc:172243) (Zgc:172243 protein)		 Danio rerio
TI:7955 None
 
E7FC79_DANRE
ZFIN»
0.0
si:cabz01113374.3 Pyruvate dehydrogenase phosphatase
regulatory subunit, mitochondrial (Si:cabz01113374.3)		 Danio rerio
TI:7955 None
 
F1NG59_CHICK
Ensembl»
0.0
PDPR Pyruvate dehydrogenase
phosphatase regulatory subunit		 Gallus gallus
TI:9031 None
   
PDPR_MOUSE
Ensembl»
0.0
Pdpr Pyruvate dehydrogenase phosphatase
regulatory subunit, mitochondrial (PDPr)		 Mus musculus
TI:10090 None
 
Q55FP7_DICDI
dictyBase»
0.0
DDB_G0268008 FAD dependent
oxidoreductase domain-containing protein		 Dictyostelium discoideum
TI:44689 None
 
A0A8V0ZUV6_CHICK
Ensembl»
0.0
FOXRED1 FAD dependent oxidoreductase domain containing 1 Gallus gallus
TI:9031 None 		     
Q5S4X7_ARATH
TAIR»
0.0
At2g22650 FAD-dependent oxidoreductase family protein Arabidopsis thaliana
TI:3702 None 		 
 
Q9FN21_ARATH
TAIR»
0.0
At5g67290 FAD-dependent oxidoreductase family protein (Similarity
to unknown protein) (Uncharacterized protein At5g67290)		 Arabidopsis thaliana
TI:3702 None 		 
 
Q9LV69_ARATH
TAIR»
0.0
MJE7.7 At5g48440 (FAD-dependent oxidoreductase family
protein) (Uncharacterized protein At5g48440)		 Arabidopsis thaliana
TI:3702 None