Collated Gene Ontology terms

Biological process: kinase activity(2023) protein kinase inhibitor activity(2014, 2023) transferase activity(2023) myosin heavy chain kinase activity(2023)

Molecular function: ribosomal large subunit biogenesis2002, 2017, 2019, 2023 regulation of signal transduction by p53 class mediator2017, 2023 phosphorylation2023 cell population proliferation2014, 2015, 2023 roof of mouth development2014, 2023 ribosome biogenesis2007, 2019, 2023 negative regulation of signal transduction2023 ribosomal large subunit assembly2007 cellular lipid metabolic process2020 regulation of microtubule cytoskeleton organization2014, 2023
regulation of actin cytoskeleton organization2014, 2023 signaling2022 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2007 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2007

Cellular component: nucleolus2014, 2015, 2018, 2021, 2023 Cul4-RING E3 ubiquitin ligase complex2008, 2023 nucleus2005, 2009, 2017, 2023 preribosome2007, 2023 membrane2012, 2023 spindle2019 nuclear membrane2023

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 16/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 3/4 
Harosa: 3/4 
Hacrobia: 0/0 
Plants: 35/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 0 2 4 6 8 10 Knownness

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
MAK11_YEAST
SGD»
4.8
MAK11 Protein MAK11 (Maintenance of killer protein 11) Saccharomyces cerevisiae
TI:4932 None
 
SKB15_SCHPO
PomBase»
3.8
skb15 Shk1 kinase-binding protein 15 Schizosaccharomyces pombe
TI:4896 None
 
PK1IP_MOUSE
Ensembl»
3.6
Pak1ip1 p21-activated protein kinase-interacting protein 1 (PAK1-interacting
protein 1) (Putative PAK inhibitor Skb15)		 Mus musculus
TI:10090 None
 
Q32PZ0_RAT
RGD»
2.0
Pak1ip1 PAK1 interacting protein 1 Rattus norvegicus
TI:10116 None
   
PK1IP_HUMAN
Ensembl»
1.6
PAK1IP1 p21-activated protein kinase-interacting protein 1 (PAK/PLC-interacting protein 1)
(hPIP1) (PAK1-interacting protein 1) (WD repeat-containing protein 84)		 Homo sapiens
TI:9606 None
 
Q9VXW4_DROME
FlyBase»
1.0
Dmel\CG9123 FI12409p Drosophila melanogaster
TI:7227 None
 
PK1IP_CHICK
CTD»
0.5
PAK1IP1 p21-activated protein kinase-interacting protein
1-like (PAK1-interacting protein 1-like)		 Gallus gallus
TI:9031 None
 
PK1IP_DANRE
ZFIN»
0.5
pak1ip1 p21-activated protein kinase-interacting protein
1-like (PAK1-interacting protein 1-like)		 Danio rerio
TI:7955 None
 
Q9VXW3_DROME
FlyBase»
0.5
Dmel\CG12608 LD30439p Drosophila melanogaster
TI:7227 None
 
A0A022R3J3_ERYGU
Ensembl»
0.0
MIMGU_mgv1a009556mg Uncharacterized protein Erythranthe guttata
TI:4155 None 		 
 
A0A059C7B8_EUCGR
EnsemblPlants»
0.0
EUGRSUZ_E02427 Uncharacterized protein Eucalyptus grandis
TI:71139 None 		 
 
A0A061GDL0_THECC
EnsemblPlants»
0.0
TCM_029434 Pak inhibitor skb15, putative Theobroma cacao
TI:3641 None
 
A0A067GJ90_CITSI
Ensembl»
0.0
CISIN_1g019326mg Anaphase-promoting complex subunit
4 WD40 domain-containing protein		 Citrus sinensis
TI:2711 None 		 
 
A0A078FE53_BRANA
EnsemblPlants»
0.0
BnaA02g13180D BnaA02g13180D protein Brassica napus
TI:3708 None 		 
 
A0A078JHK3_BRANA
EnsemblPlants»
0.0
BnaC02g46010D (rape) hypothetical
protein (BnaC02g46010D protein)		 Brassica napus
TI:3708 None 		 
 
A0A0A0KIP0_CUCSA
EnsemblPlants»
0.0
Csa_6G524070 Uncharacterized protein Cucumis sativus
TI:3659 None
 
A0A0D1DWR7_USTMA
EnsemblFungi»
0.0
UMAG_04067 Uncharacterized protein Ustilago maydis
TI:5270 None 		 
 
A0A0K9PA00_ZOSMR
EnsemblPlants»
0.0
ZOSMA_30G00710 p21-activated protein kinase-interacting
protein 1-like protein		 Zostera marina
TI:29655 None
 
A0A0S2M615_CRYNJ
EnsemblFungi»
0.0
CNK02385 Uncharacterized protein Cryptococcus neoformans
TI:5207 None 		 
 
A0A1D8PMA9_CANAL
EnsemblFungi»
0.0
CAALFM_C405330CA orf19.9357 Protein MAK11 Candida albicans
TI:5476 None 		 
 
A0A1S3ZPX6_TOBAC
EnsemblFungi»
0.0
LOC107789172 P21-activated protein
kinase-interacting protein 1		 Nicotiana tabacum
TI:4097 None
   
A0A1S4BYU8_TOBAC
EnsemblFungi»
0.0
LOC107813337 P21-activated protein
kinase-interacting protein 1-like		 Nicotiana tabacum
TI:4097 None
   
A0A1U7Z5K8_NELNU
EnsemblBacteria»
0.0
LOC104589466 P21-activated protein
kinase-interacting protein 1-like		 Nelumbo nucifera
TI:4432 None
 
A0A1U8K5Z7_GOSHI
Ensembl»
0.0
LOC107913807 P21-activated protein
kinase-interacting protein 1-like		 Gossypium hirsutum
TI:3635 None
   
A0A1U8MGD1_GOSHI
Ensembl»
0.0
LOC107937494 P21-activated protein kinase-interacting
protein 1-like isoform X1		 Gossypium hirsutum
TI:3635 None
   
A0A1Y1I534_KLENI
EnsemblPlants»
0.0
KFL_002680060 Uncharacterized protein Klebsormidium nitens
TI:105231 None 		 
 
A0A251RTI7_HELAN
EnsemblPlants»
0.0
HannXRQ_Chr17g0564621 HanXRQr2_Chr17g0823661 Putative transducin/WD40 repeat-like superfamily
protein (Transcription factor WD40-like family)		 Helianthus annuus
TI:4232 None
 
A0A2C9U5V6_MANES
EnsemblPlants»
0.0
MANES_17G073300 Uncharacterized protein Manihot esculenta
TI:3983 None
 
A0A2I4EK20_JUGRE
EnsemblPlants»
0.0
LOC108990277 P21-activated protein
kinase-interacting protein 1-like		 Juglans regia
TI:51240 None
 
A0A2I4GUT3_JUGRE
EnsemblPlants»
0.0
LOC109011064 P21-activated protein
kinase-interacting protein 1-like		 Juglans regia
TI:51240 None
 
A0A2K1JEI5_PHYPA
EnsemblPlants»
0.0
PHYPA_020214 Uncharacterized protein Physcomitrium patens
TI:3218 None 		 
 
A0A2K1K4H9_PHYPA
EnsemblPlants»
0.0
PHYPA_013151 Uncharacterized protein Physcomitrium patens
TI:3218 None 		 
 
A0A2K1YBY1_POPTR
EnsemblPlants»
0.0
POPTR_012G107400 Uncharacterized protein Populus trichocarpa
TI:3694 None
 
A0A2K3DZ45_CHLRE
EnsemblPlants»
0.0
CHLRE_03g205800v5 Uncharacterized protein Chlamydomonas reinhardtii
TI:3055 None 		 
 
A0A2R6XWU8_MARPO
EnsemblPlants»
0.0
MARPO_0001s0498 Uncharacterized protein Marchantia polymorpha
TI:3197 None 		 
 
A0A3B6KC26_WHEAT
EnsemblPlants»
0.0
Uncharacterized protein Triticum aestivum
TI:4565 None
   
A0A3B6LFN6_WHEAT
EnsemblPlants»
0.0
CFC21_069799 Uncharacterized protein Triticum aestivum
TI:4565 None
 
A0A3B6MLP1_WHEAT
EnsemblPlants»
0.0
CFC21_075798 Uncharacterized protein Triticum aestivum
TI:4565 None
 
A0A5F8A1L0_MACMU
Ensembl»
0.0
PAK1IP1 PAK1 interacting protein 1 Macaca mulatta
TI:9544 None
   
A0A6I8N709_ORNAN
Ensembl»
0.0
PAK1IP1 PAK1 interacting protein 1 Ornithorhynchus anatinus
TI:9258 None 		     
A0A7M7NKN3_STRPU
EnsemblMetazoa»
0.0
P21-activated protein
kinase-interacting protein 1-like		 Strongylocentrotus purpuratus
TI:7668 None 		     
A0A7M7NPL6_STRPU
EnsemblMetazoa»
0.0
Uncharacterized protein Strongylocentrotus purpuratus
TI:7668 None 		     
A0A7M7REQ4_STRPU
EnsemblMetazoa»
0.0
P21-activated protein
kinase-interacting protein 1-like		 Strongylocentrotus purpuratus
TI:7668 None 		     
A0A804IYE2_MUSAM
EnsemblPlants»
0.0
GSMUA_144130.1 (wild Malaysian banana) hypothetical protein Musa acuminata
TI:4641 None 		 
 
A0A8I3S180_CANLF
Ensembl»
0.0
PAK1IP1 PAK1 interacting protein 1 Canis lupus
TI:9612 None
   
A0A8I6XSU0_HORVV
EnsemblPlants»
0.0
Uncharacterized protein Hordeum vulgare
TI:4513 None 		     
A0A8V0Y560_CHICK
Ensembl»
0.0
PAK1IP1 PAK1 interacting protein 1 Gallus gallus
TI:9031 None 		     
A0A9J7KPG8_BRAFL
CTD»
0.0
LOC118410297 P21-activated protein
kinase-interacting protein 1-like		 Branchiostoma floridae
TI:7739 None
   
A0BYN4_PARTE
EnsemblProtists»
0.0
GSPATT00033504001 Chromosome undetermined scaffold_137,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None 		 
 
A0CT75_PARTE
EnsemblProtists»
0.0
GSPATT00010226001 Chromosome undetermined scaffold_27,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None 		 
 
A7EKY8_SCLS1
EnsemblFungi»
0.0
SS1G_05985 60S ribosome biogenesis protein Mak11 Sclerotinia sclerotiorum
TI:5180 None 		 
 
A7SCC7_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g244276 P21-activated protein
kinase-interacting protein 1-like		 Nematostella vectensis
TI:45351 None 		 
 
A8B9E8_GIAIC
EnsemblProtists»
0.0
GL50803_0015581 GL50803_15581 WD40 repeat protein Giardia intestinalis
TI:5741 None 		 
 
A9UZS8_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_32482 Uncharacterized protein Monosiga brevicollis
TI:81824 None 		 
 
B3S2Q6_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_58111 Uncharacterized protein Trichoplax adhaerens
TI:10228 None 		 
 
B4FF35_MAIZE
EnsemblPlants»
0.0
ZEAMMB73_Zm00001d022257 Transducin/WD40 repeat-like superfamily protein Zea mays
TI:4577 None
 
B6JYZ8_SCHJY
EnsemblFungi»
0.0
SJAG_01821 Shk1 kinase binding protein 15 Schizosaccharomyces japonicus
TI:4897 None
 
B7QLZ6_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW023084 U3 snoRNP-associated protein,
putative (EC 2.7.11.7)		 Ixodes scapularis
TI:6945 None
 
B8C2L6_THAPS
EnsemblProtists»
0.0
THAPSDRAFT_268880 WD40-repeat protein Thalassiosira pseudonana
TI:35128 None 		 
 
B9T810_RICCO
EnsemblBacteria»
0.0
RCOM_0229960 Pak inhibitor skb15, putative Ricinus communis
TI:3988 None 		 
 
C4LZA3_ENTH1
EnsemblProtists»
0.0
EHI_000520 WD domain containing protein Entamoeba histolytica
TI:5759 None 		 
 
C5YS24_SORBI
EnsemblPlants»
0.0
SORBI_3008G171800 Uncharacterized protein Sorghum bicolor
TI:4558 None
 
D6WDJ5_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_03673 p21-activated protein
kinase-interacting protein 1-like		 Tribolium castaneum
TI:7070 None
 
D7THM7_VITVI
EnsemblPlants»
0.0
VIT_08s0007g00490 Uncharacterized protein Vitis vinifera
TI:29760 None 		 
 
D8QWZ4_SELML
EnsemblPlants»
0.0
SELMODRAFT_80824 Uncharacterized protein Selaginella moellendorffii
TI:88036 None 		 
 
D8RL30_SELML
EnsemblPlants»
0.0
SELMODRAFT_96087 Uncharacterized protein Selaginella moellendorffii
TI:88036 None 		 
 
E3KTZ1_PUCGT
EnsemblFungi»
0.0
PGTG_13472 Uncharacterized protein Puccinia graminis
TI:5297 None 		 
 
E9HF40_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_300865 Uncharacterized protein Daphnia pulex
TI:6669 None 		 
 
F0ZP01_DICPU
EnsemblProtists»
0.0
DICPUDRAFT_8425 Uncharacterized protein Dictyostelium purpureum
TI:5786 None 		 
 
F1MRA9_BOVIN
Ensembl»
0.0
PAK1IP1 PAK1 interacting protein 1 Bos taurus
TI:9913 None
   
F4PBZ2_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_4260 Uncharacterized protein Batrachochytrium dendrobatidis
TI:109871 None 		 
 
F6S934_MONDO
Ensembl»
0.0
PAK1IP1 PAK1 interacting protein 1 Monodelphis domestica
TI:13616 None
   
F7AXC6_CIOIN
Ensembl»
0.0
Uncharacterized protein Ciona intestinalis
TI:7719 None 		 
 
G1KCQ1_ANOCA
Ensembl»
0.0
pak1ip1 Uncharacterized protein Anolis carolinensis
TI:28377 None 		     
G3RB71_GORGO
Ensembl»
0.0
PAK1IP1 PAK1 interacting protein 1 Gorilla gorilla
TI:9593 None
 
G7IIU2_MEDTR
EnsemblPlants»
0.0
11417690 P21-activated kinase-interacting-like protein (Putative
transcription factor WD40-like family)		 Medicago truncatula
TI:3880 None
 
H2LF78_ORYLA
Ensembl»
0.0
pak1ip1 PAK1 interacting protein 1 Oryzias latipes
TI:8090 None 		     
H2QSA5_PANTR
Ensembl»
0.0
PAK1IP1 PAK1 interacting protein 1 Pan troglodytes
TI:9598 None
 
H3H107_PHYRM
EnsemblProtists»
0.0
Uncharacterized protein Phytophthora ramorum
TI:164328 None 		 
 
I1IGE2_BRADI
EnsemblPlants»
0.0
100831381 Anaphase-promoting complex subunit
4 WD40 domain-containing protein		 Brachypodium distachyon
TI:15368 None
 
I1L241_SOYBN
EnsemblPlants»
0.0
100782530 Uncharacterized protein Glycine max
TI:3847 None 		 
 
I1MHU7_SOYBN
EnsemblPlants»
0.0
100777673 Uncharacterized protein Glycine max
TI:3847 None 		 
 
K3Z7Z8_SETIT
EnsemblPlants»
0.0
101774703 Uncharacterized protein Setaria italica
TI:4555 None
 
K7GSP8_PIG
Ensembl»
0.0
PAK1IP1 PAK1 interacting protein 1 Sus scrofa
TI:9823 None
   
M1C1L0_SOLTU
EnsemblPlants»
0.0
102580729 Pak inhibitor skb15 Solanum tuberosum
TI:4113 None
   
M3VWY5_FELCA
Ensembl»
0.0
PAK1IP1 PAK1 interacting protein 1 Felis catus
TI:9685 None
 
M5XA34_PRUPE
EnsemblPlants»
0.0
PRUPE_4G084200 Uncharacterized protein Prunus persica
TI:3760 None 		 
 
PK1IP_BOVIN
CTD»
0.0
PAK1IP1 p21-activated protein kinase-interacting protein
1 (PAK1-interacting protein 1)		 Bos taurus
TI:9913 None
 
Q0ILW8_ORYSJ
EnsemblPlants»
0.0
Os12g0615900 Os12g0615900 protein Oryza sativa
TI:4530 None
 
Q0UWS1_PHANO
EnsemblFungi»
0.0
SNOG_03793 60S ribosome biogenesis protein Mak11 Phaeosphaeria nodorum
TI:13684 None 		 
 
Q28FT6_XENTR
Xenbase»
0.0
pak1ip1 P21-activated protein kinase-interacting protein
1 (PAK1 interacting protein 1)		 Xenopus tropicalis
TI:8364 None
 
Q4Q624_LEIMA
EnsemblProtists»
0.0
LMJF_31_2370 Uncharacterized protein Leishmania major
TI:5664 None 		 
 
Q4WP04_ASPFU
EnsemblFungi»
0.0
AFUA_4G07570 60S ribosome biogenesis protein Mak11, putative Aspergillus fumigatus
TI:746128 None 		 
 
Q57YU9_TRYB2
VEuPathDB»
0.0
Tb08.10K10.50 Guanine nucleotide-binding protein
subunit beta-like protein		 Trypanosoma brucei
TI:5691 None
 
Q584L0_TRYB2
VEuPathDB»
0.0
Tb04.3M17.270 Uncharacterized protein Trypanosoma brucei
TI:5691 None
 
Q5B4Q9_EMENI
EnsemblFungi»
0.0
ANIA_04471 60S ribosome biogenesis protein
Mak11, putative (AFU_orthologue AFUA_4G07570)		 Emericella nidulans
TI:162425 None 		 
 
Q5XEV4_ARATH
TAIR»
0.0
At1g65030 At1g65030 (Transducin/WD40
repeat-like superfamily protein)		 Arabidopsis thaliana
TI:3702 None
 
Q6C1X4_YARLI
EnsemblFungi»
0.0
YALI0_F12661g YALI0F12661p Yarrowia lipolytica
TI:4952 None 		 
 
Q75BV5_ASHGO
EnsemblFungi»
0.0
AGOS_ACR166W ACR166Wp Ashbya gossypii
TI:33169 None 		 
 
Q7PX06_ANOGA
EnsemblMetazoa»
0.0
1282017 AGAP001149-PA Anopheles gambiae
TI:7165 None 		 
 
Q7SBU5_NEUCR
EnsemblFungi»
0.0
NCU07864 60S ribosome biogenesis protein Mak11 Neurospora crassa
TI:5141 None 		 
 
Q86HN6_DICDI
dictyBase»
0.0
DDB_G0274505 Uncharacterized protein Dictyostelium discoideum
TI:44689 None 		 
 
T1FSD7_HELRO
EnsemblMetazoa»
0.0
20211734 Uncharacterized protein Helobdella robusta
TI:6412 None 		 
 
U5CSE9_AMBTC
EnsemblPlants»
0.0
AMTR_s00030p00230030 Uncharacterized protein Amborella trichopoda
TI:13333 None 		 
 
W1NUD4_AMBTC
EnsemblPlants»
0.0
AMTR_s00092p00076290 Anaphase-promoting complex subunit
4 WD40 domain-containing protein		 Amborella trichopoda
TI:13333 None 		 
 
W5N6G2_LEPOC
Ensembl»
0.0
PAK1 interacting protein 1 Lepisosteus oculatus
TI:7918 None