Collated Gene Ontology terms

Biological process: hydrolase activity(2025) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen(2025) oxidoreductase activity(2025) monooxygenase activity(2025) metal ion binding(2025) iron ion binding(2025) heme binding(2025) DNA binding(2025)

Molecular function: negative regulation of ossification2022, 2025 negative regulation of BMP signaling pathway2022, 2025 regulation of nucleocytoplasmic transport2022, 2025 negative regulation of osteoblast differentiation2022, 2025

Cellular component: nuclear outer membrane2022, 2025 nuclear membrane2022, 2025 peroxisome2010, 2025 endomembrane system2025 nucleus2014, 2018 lipid droplet2018, 2025 nuclear envelope2018, 2025 endoplasmic reticulum2018, 2025 mitochondrion2012

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 0/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 5/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 1/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 40/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
Q9LHE8_ARATH
TAIR»
0.0
At3g19970 AT3g19970/MZE19_2 (Alpha/beta-Hydrolases
superfamily protein)		 Arabidopsis thaliana
TI:3702 None
 
Q8S8G6_ARATH
TAIR»
0.0
At2g18245 Alpha/beta-Hydrolases superfamily protein
(At2g18245) (Expressed protein)		 Arabidopsis thaliana
TI:3702 None 		 
 
Q8S8H8_ARATH
TAIR»
0.0
At2g15695 At2g15695 Arabidopsis thaliana
TI:3702 None
 
Q9FFG7_ARATH
TAIR»
0.0
MLN1.18 At5g44250 (Similarity to unknown protein) Arabidopsis thaliana
TI:3702 None
 
Q9TZH9_CAEEL
WormBase»
0.0
CELE_T10B11.5 T10B11.5 DUF1273 family protein Caenorhabditis elegans
TI:6239 None
 
A1Z6G9_DROME
FlyBase»
0.0
Dmel\CG8245 FI18173p1 Drosophila melanogaster
TI:7227 None
 
Q54GW6_DICDI
dictyBase»
0.0
DDB_G0289887 Serine hydrolase FSH domain-containing protein Dictyostelium discoideum
TI:44689 None 		 
 
A0A1L1RPU6_CHICK
Ensembl»
0.0
TMEM53 Transmembrane protein 53 Gallus gallus
TI:9031 None
   
D3ZPB8_RAT
RGD»
0.0
Tmem53 Transmembrane protein 53 Rattus norvegicus
TI:10116 None
   
Q17846_CAEEL
WormBase»
0.0
C09B8.4 CELE_C09B8.4 Transmembrane protein 53 Caenorhabditis elegans
TI:6239 None
 
Q22750_CAEEL
WormBase»
0.0
CELE_T24H10.4 T24H10.4 Transmembrane protein 53 Caenorhabditis elegans
TI:6239 None 		 
 
Q54N85_DICDI
dictyBase»
0.0
DDB_G0285447 Transmembrane protein 53 Dictyostelium discoideum
TI:44689 None 		 
 
Q54YR8_DICDI
dictyBase»
0.0
DDB_G0278115 Transmembrane protein 53 Dictyostelium discoideum
TI:44689 None
 
Q9TZH8_CAEEL
WormBase»
0.0
CELE_T10B11.6 T10B11.6 Transmembrane protein 53 Caenorhabditis elegans
TI:6239 None
 
TMM53_DANRE
ZFIN»
2.0
tmem53 Transmembrane protein 53 Danio rerio
TI:7955 None
 
TMM53_HUMAN
Ensembl»
2.9
TMEM53 Transmembrane protein 53 (Nuclear
envelope transmembrane protein 4)		 Homo sapiens
TI:9606 None
 
TMM53_MOUSE
Ensembl»
5.7
Tmem53 Transmembrane protein 53 (Nuclear
envelope transmembrane protein 4)		 Mus musculus
TI:10090 None
 
B0G0Z2_DICDI
dictyBase»
0.0
DDB_G0269944 Uncharacterized protein Dictyostelium discoideum
TI:44689 None 		 
 
Q54XU1_DICDI
dictyBase»
0.0
DDB_G0278745 Uncharacterized protein Dictyostelium discoideum
TI:44689 None 		 
 
Q54XU2_DICDI
dictyBase»
0.0
DDB_G0278743 Uncharacterized protein Dictyostelium discoideum
TI:44689 None 		 
 
Q557K5_DICDI
dictyBase»
0.0
DDB_G0273463 DDB_G0273499 Uncharacterized protein Dictyostelium discoideum
TI:44689 None 		 
 
Q86IZ7_DICDI
dictyBase»
0.0
DDB_G0274319 Uncharacterized protein Dictyostelium discoideum
TI:44689 None