Collated Gene Ontology terms

Biological process: abscisic acid binding(2009, 2017, 2025) voltage-gated monoatomic anion channel activity(2010, 2016, 2017, 2025) GTPase binding(2009, 2015, 2025) GTP binding(2009, 2025) protease binding(2017, 2025) nucleotide binding(2025) lyase activity(2025) enoyl-CoA hydratase activity(2025) catalytic activity(2025)

Molecular function: response to abscisic acid2009, 2017, 2025 intracellular pH reduction2010, 2016, 2017, 2025 monoatomic anion transmembrane transport2025 cellular response to cold2015, 2025 T cell differentiation2020, 2025 protein transport2025 monoatomic ion transport2025 monoatomic ion transmembrane transport2025 vegetative to reproductive phase transition of meristem2009 post-embryonic development2009
sorocarp development2014 skin development2013 secretion by cell2014 regulation of gene expression2014 protein secretion2014 positive regulation of canonical NF-kappaB signal transduction2010 oligopeptide transport2019 lipid metabolic process2025 fatty acid metabolic process2025 endosomal lumen acidification2014 cell motility2024 Golgi organization2014

Cellular component: membrane2016, 2025 Golgi cisterna membrane2010, 2017, 2025 plasma membrane2009, 2015, 2025 endoplasmic reticulum membrane2014, 2015, 2025 Golgi membrane2014, 2025 monoatomic ion channel complex2025 Golgi-associated vesicle membrane2010, 2025 nuclear lumen2025 mitochondrion2018 endoplasmic reticulum2014
cytoplasm2025 chloroplast2018 apicoplast2015

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 11/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 2/4 
Harosa: 3/4 
Hacrobia: 0/0 
Plants: 38/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
GPHRA_HUMAN
Ensembl»
3.6
GPR89A Golgi pH regulator A (Protein GPR89A) (Putative
MAPK-activating protein PM01) (Putative NF-kappa-B-activating protein 90)		 Homo sapiens
TI:9606 None
 
GPHRB_HUMAN
Ensembl»
1.5
GPR89B Golgi pH regulator B (Protein GPR89B) Homo sapiens
TI:9606 None
 
GTG2_ARATH
TAIR»
5.8
GTG2 GPCR-type G protein 2 Arabidopsis thaliana
TI:3702 None
 
H2PZU7_PANTR
Ensembl»
0.0
GPR89A G protein-coupled receptor 89A
(G protein-coupled receptor 89B)		 Pan troglodytes
TI:9598 None
 
COLD1_ORYSJ
EnsemblPlants»
0.0
COLD1 GPCR-type G protein COLD1
(Protein CHILLING TOLERANCE DIVERGENCE 1)		 Oryza sativa
TI:4530 None
 
GTG1_ARATH
TAIR»
5.8
GTG1 GPCR-type G protein 1 Arabidopsis thaliana
TI:3702 None
 
B7PNF1_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW005452 Uncharacterized protein Ixodes scapularis
TI:6945 None 		 
 
B9I733_POPTR
neXtProt»
0.0
POPTR_013G077700 Abscisic acid G-protein
coupled receptor-like domain-containing protein		 Populus trichocarpa
TI:3694 None
 
GPHR_BOVIN
Ensembl»
0.0
GPR89 Golgi pH regulator (Protein GPR89) Bos taurus
TI:9913 None
 
GPHR_MOUSE
Ensembl»
4.1
Gpr89 Golgi pH regulator (Protein GPR89) Mus musculus
TI:10090 None
 
K3Y738_SETIT
EnsemblPlants»
0.0
LOC101771561 Abscisic acid G-protein
coupled receptor-like domain-containing protein		 Setaria italica
TI:4555 None
 
A0A251S094_HELAN
neXtProt»
0.0
GTG1 Putative GPCR-type G protein 1
(The Golgi pH regulator/GPCR-type G protein)		 Helianthus annuus
TI:4232 None
 
A0A2K3CVT4_CHLRE
euHCVdb»
0.0
CHLRE_16g674739v5 Abscisic acid G-protein
coupled receptor-like domain-containing protein		 Chlamydomonas reinhardtii
TI:3055 None
 
A0A398AML6_BRACM
EnsemblPlants»
0.0
BRAPAZ1V2_A01P19230.2 BRARA_A01735 Abscisic acid G-protein
coupled receptor-like domain-containing protein		 Brassica campestris
TI:3711 None
 
A0A480K5T2_PIG
Ensembl»
0.0
LOC100154179 Golgi pH regulator A isoform 1 Sus scrofa
TI:9823 None
 
B9IPW8_POPTR
euHCVdb»
0.0
POPTR_019G042200 Abscisic acid G-protein
coupled receptor-like domain-containing protein		 Populus trichocarpa
TI:3694 None 		 
 
F7D013_MACMU
Ensembl»
0.0
GPR89A G protein-coupled receptor 89A
(Golgi pH regulator B)		 Macaca mulatta
TI:9544 None
 
K7LSF6_SOYBN
EnsemblPlants»
0.0
LOC100788295 Abscisic acid G-protein
coupled receptor-like domain-containing protein		 Glycine max
TI:3847 None
 
Q3ZAN1_DROME
FlyBase»
4.2
GPHR Golgi pH regulator (LD13915p) Drosophila melanogaster
TI:7227 None
 
Q580H0_TRYB2
TubercuList»
0.0
Tb08.29O9.220 Golgi pH regulator
conserved domain-containing protein		 Trypanosoma brucei
TI:5691 None
 
T1ED69_HELRO
EnsemblMetazoa»
0.0
20194521 Abscisic acid G-protein
coupled receptor-like domain-containing protein		 Helobdella robusta
TI:6412 None
 
YHN8_YEAST
SGD»
0.0
YHR078W Uncharacterized protein YHR078W Saccharomyces cerevisiae
TI:4932 None
 
A0A022Q8K3_ERYGU
euHCVdb»
0.0
MIMGU_mgv1a005832mg Abscisic acid G-protein
coupled receptor-like domain-containing protein		 Erythranthe guttata
TI:4155 None
 
A0A061EZK0_THECC
euHCVdb»
0.0
TCM_025560 GPCR-type G protein 1 isoform 1 Theobroma cacao
TI:3641 None
 
A0A067DYS3_CITSI
neXtProt»
0.0
CISIN_1g012223mg Abscisic acid G-protein
coupled receptor-like domain-containing protein		 Citrus sinensis
TI:2711 None
 
A0A078FU60_BRANA
euHCVdb»
0.0
BnaA02g11860D BnaA02g11860D protein Brassica napus
TI:3708 None
 
A0A078G1A0_BRANA
euHCVdb»
0.0
BnaC01g20220D BnaC01g20220D protein Brassica napus
TI:3708 None
 
A0A078ISN8_BRANA
euHCVdb»
0.0
BnaAnng11860D BnaAnng11860D protein Brassica napus
TI:3708 None
 
A0A0A0LIT1_CUCSA
euHCVdb»
0.0
Csa_2G233760 GPCR-type G protein 1 Cucumis sativus
TI:3659 None
 
A0A0K9Q0N2_ZOSMR
euHCVdb»
0.0
ZOSMA_123G00570 Golgi pH regulator Zostera marina
TI:29655 None
 
A0A0R0HQ29_SOYBN
EnsemblPlants»
0.0
GLYMA_11G109900 Abscisic acid G-protein
coupled receptor-like domain-containing protein		 Glycine max
TI:3847 None
 
A0A144A1F3_PLAF7
TubercuList»
0.0
PF3D7_1420500 Protein GPR89, putative Plasmodium falciparum
TI:5833 None
 
A0A1B6PN16_SORBI
euHCVdb»
0.0
SORBI_3006G203300 Abscisic acid G-protein
coupled receptor-like domain-containing protein		 Sorghum bicolor
TI:4558 None
 
A0A1D8PDJ2_CANAL
CGD»
0.0
CAALFM_C105280WA orf19.8068 Golgi pH regulator Candida albicans
TI:5476 None
 
A0A1S4H771_ANOGA
EnsemblMetazoa»
0.0
G-protein coupled receptor Anopheles gambiae
TI:7165 None
 
A0A1Y1I901_KLENI
euHCVdb»
0.0
KFL_003260060 GPCR-type G protein Klebsormidium nitens
TI:105231 None
 
A0A2C9VGS8_MANES
euHCVdb»
0.0
MANES_08G160900v8 Abscisic acid G-protein
coupled receptor-like domain-containing protein		 Manihot esculenta
TI:3983 None
 
A0A2G2Z1P4_CAPAN
euHCVdb»
0.0
T459_19469 GPCR-type G protein 1 Capsicum annuum
TI:4072 None
 
A0A2R6WG46_MARPO
euHCVdb»
0.0
MARPO_0094s0006 Abscisic acid G-protein
coupled receptor-like domain-containing protein		 Marchantia polymorpha
TI:3197 None
 
A0A2X0SA68_WHEAT
EnsemblPlants»
0.0
LOC123054414 DWARF1 Triticum aestivum
TI:4565 None
 
A0A3B6B5K4_WHEAT
EnsemblPlants»
0.0
LOC123190297 DWARF1 Triticum aestivum
TI:4565 None
 
A0A3B6CC78_WHEAT
EnsemblPlants»
0.0
LOC123046557 DWARF1 Triticum aestivum
TI:4565 None
 
A0A7U2EXP3_PHANO
TubercuList»
0.0
JI435_080790 Abscisic acid G-protein
coupled receptor-like domain-containing protein		 Phaeosphaeria nodorum
TI:13684 None
 
A0A804JC15_MUSAM
EnsemblPlants»
0.0
GSMUA_149240.1 (wild Malaysian banana) hypothetical protein Musa acuminata
TI:4641 None
 
A0A9R1WT91_LACSA
euHCVdb»
0.0
LSAT_V11C900476180 Abscisic acid G-protein
coupled receptor-like domain-containing protein		 Lactuca sativa
TI:4236 None
 
A0BKB9_PARTE
euHCVdb»
0.0
GSPATT00029617001 Abscisic acid G-protein
coupled receptor-like domain-containing protein		 Paramecium tetraurelia
TI:5888 None
 
A7E5I1_SCLS1
TubercuList»
0.0
SS1G_00556 Abscisic acid G-protein
coupled receptor-like domain-containing protein		 Sclerotinia sclerotiorum
TI:5180 None
 
A7SPG4_NEMVE
neXtProt»
0.0
NEMVEDRAFT_v1g192049 Golgi pH regulator Nematostella vectensis
TI:45351 None
 
A8X546_CAEBR
WormBase»
0.0
CBG07249 CBG_07249 Protein CBG07249 Caenorhabditis briggsae
TI:6238 None
 
A8Y3D2_CAEBR
WormBase»
0.0
CBG23048 CBG_23048 Protein CBG23048 Caenorhabditis briggsae
TI:6238 None
 
A9V569_MONBE
euHCVdb»
0.0
MONBRDRAFT_33399 Abscisic acid G-protein
coupled receptor-like domain-containing protein		 Monosiga brevicollis
TI:81824 None
 
B3RTM1_TRIAD
CTD»
0.0
TRIADDRAFT_23402 Abscisic acid G-protein
coupled receptor-like domain-containing protein		 Trichoplax adhaerens
TI:10228 None
 
B9S266_RICCO
neXtProt»
0.0
RCOM_1328090 Protein GPR89A, putative Ricinus communis
TI:3988 None
 
C3Z493_BRAFL
neXtProt»
0.0
LOC118425714 Golgi pH regulator-like Branchiostoma floridae
TI:7739 None
 
C4LVA8_ENTH1
TubercuList»
0.0
EHI_196900 Abscisic acid G-protein
coupled receptor-like domain-containing protein		 Entamoeba histolytica
TI:5759 None
 
D2CFW7_TRICA
neXtProt»
0.0
AUGUSTUS-3.0.2_10568 Golgi pH regulator-like Protein Tribolium castaneum
TI:7070 None
 
D7T7J6_VITVI
euHCVdb»
0.0
VIT_16s0039g01460 GPCR-type G protein 1 Vitis vinifera
TI:29760 None
 
D8SSN0_SELML
neXtProt»
0.0
SELMODRAFT_235006 Abscisic acid G-protein
coupled receptor-like domain-containing protein		 Selaginella moellendorffii
TI:88036 None
 
D8SZC5_SELML
neXtProt»
0.0
SELMODRAFT_235594 Abscisic acid G-protein
coupled receptor-like domain-containing protein		 Selaginella moellendorffii
TI:88036 None
 
E3K5A2_PUCGT
TubercuList»
0.0
PGTG_06019 Golgi pH regulator
conserved domain-containing protein		 Puccinia graminis
TI:5297 None
 
E7FB29_DANRE
ZFIN»
1.0
si:ch73-390b10.2 Golgi pH regulator (Si:ch73-390b10.2) Danio rerio
TI:7955 None
 
F0ZSY7_DICPU
TubercuList»
0.0
DICPUDRAFT_9193 Golgi pH regulator Dictyostelium purpureum
TI:5786 None
 
F4P2P5_BATDJ
euHCVdb»
0.0
BATDEDRAFT_11317 Abscisic acid G-protein
coupled receptor-like domain-containing protein		 Batrachochytrium dendrobatidis
TI:109871 None
 
G7K0Z9_MEDTR
EnsemblPlants»
0.0
MTR_5g005440 GPCR-type G protein Medicago truncatula
TI:3880 None
 
GPHR_CHICK
Ensembl»
2.0
GPR89 Golgi pH regulator (Protein GPR89) Gallus gallus
TI:9031 None
 
GPHR_DICDI
dictyBase»
4.8
gpr89 Golgi pH regulator homolog (Protein GPR89) Dictyostelium discoideum
TI:44689 None
 
GPHR_XENLA
Xenbase»
0.0
gpr89-b Golgi pH regulator (Protein gpr89b) Xenopus laevis
TI:8355 None
 
H3GVB3_PHYRM
EnsemblProtists»
0.0
Abscisic acid G-protein
coupled receptor-like domain-containing protein		 Phytophthora ramorum
TI:164328 None
 
I1J1E4_BRADI
EnsemblPlants»
0.0
LOC100825374 Abscisic acid G-protein
coupled receptor-like domain-containing protein		 Brachypodium distachyon
TI:15368 None
 
K7U6H0_MAIZE
EnsemblPlants»
0.0
LOC100272676 GPCR-type G protein 2 Zea mays
TI:4577 None
 
M5XRE0_PRUPE
euHCVdb»
0.0
PRUPE_2G329100 Abscisic acid G-protein
coupled receptor-like domain-containing protein		 Prunus persica
TI:3760 None
 
Q17912_CAEEL
WormBase»
1.0
gphr-2 Golgi pH regulator Caenorhabditis elegans
TI:6239 None
 
Q4QIR1_LEIMA
TubercuList»
0.0
LMJF_07_0330 Abscisic acid G-protein
coupled receptor-like domain-containing protein		 Leishmania major
TI:5664 None
 
Q5K8V4_CRYD1
TubercuList»
0.0
CNL04370 Expressed protein Cryptococcus deneoformans
TI:40410 None
 
Q6CED7_YARLI
TubercuList»
0.0
YALI0_B16478g YALI0B16478p Yarrowia lipolytica
TI:4952 None
 
Q74Z40_EREGS
euHCVdb»
0.0
AGOS_AGR366W AGR366Wp Eremothecium gossypii
TI:33169 None
 
Q7RYA0_NEUCR
TubercuList»
0.0
NCU00005 G protein-coupled receptor Neurospora crassa
TI:5141 None
 
Q8IJV9_PLAF7
TubercuList»
0.0
PF3D7_1008500 Protein GPR89, putative Plasmodium falciparum
TI:5833 None
 
Q9U1S3_CAEEL
WormBase»
1.0
gphr-1 Golgi pH regulator Caenorhabditis elegans
TI:6239 None
 
U5D5Q3_AMBTC
euHCVdb»
0.0
AMTR_s00048p00216790 Abscisic acid G-protein
coupled receptor-like domain-containing protein		 Amborella trichopoda
TI:13333 None
 
W5MQW3_LEPOC
Ensembl»
0.0
G protein-coupled receptor 89B Lepisosteus oculatus
TI:7918 None
 
A0A1S3XIL1_TOBAC
euHCVdb»
0.0
LOC107765600 GPCR-type G protein 1-like Nicotiana tabacum
TI:4097 None
   
A0A1S4AAC3_TOBAC
euHCVdb»
0.0
LOC107795463 GPCR-type G protein 1 Nicotiana tabacum
TI:4097 None
   
A0A1U7ZUK5_NELNU
euHCVdb»
0.0
LOC104596393 GPCR-type G protein 1-like Nelumbo nucifera
TI:4432 None
   
A0A1U8BFI6_NELNU
neXtProt»
0.0
LOC104612894 GPCR-type G protein 1 Nelumbo nucifera
TI:4432 None
   
A0A1U8NX34_GOSHI
neXtProt»
0.0
LOC107951881 GPCR-type G protein 1 Gossypium hirsutum
TI:3635 None
   
A0A2A6C8S2_PRIPA
EnsemblMetazoa»
0.0
WBGene00107196 Probable enoyl-CoA hydratase,
mitochondrial (EC 4.2.1.17)		 Pristionchus pacificus
TI:54126 None
   
A0A2I4GRK8_JUGRE
euHCVdb»
0.0
LOC109010218 GPCR-type G protein 1 Juglans regia
TI:51240 None
   
A0A3Q7HAD7_SOLLC
EnsemblPlants»
0.0
LOC101263432 Abscisic acid G-protein
coupled receptor-like domain-containing protein		 Solanum lycopersicum
TI:4081 None
   
A0A3Q7HD92_SOLLC
EnsemblPlants»
0.0
Uncharacterized protein Solanum lycopersicum
TI:4081 None 		     
A0A5F8GF32_MONDO
Ensembl»
0.0
GPR89A Golgi pH regulator Monodelphis domestica
TI:13616 None
   
A0A6I8S7Z1_XENTR
Xenbase»
0.0
gpr89b G protein-coupled receptor 89B
(Golgi pH regulator B)		 Xenopus tropicalis
TI:8364 None
   
A0A7M7NBA7_STRPU
EnsemblMetazoa»
0.0
Golgi pH regulator Strongylocentrotus purpuratus
TI:7668 None
   
A0A8I3RXH8_CANLF
Ensembl»
0.0
GPR89A G protein-coupled receptor 89A Canis lupus
TI:9612 None
   
A0A8I6WVU9_HORVV
EnsemblPlants»
0.0
LOC123427727 DWARF1 Hordeum vulgare
TI:4513 None
   
A0A9L0SUF9_HORSE
Ensembl»
0.0
GPR89A G protein-coupled receptor 89B Equus caballus
TI:9796 None
   
A0A9R0K0U3_SPIOL
euHCVdb»
0.0
LOC110793110 GPCR-type G protein 2 isoform X1 Spinacia oleracea
TI:3562 None
   
A0ABI7ZKZ9_FELCA
Ensembl»
0.0
GPR89A G protein-coupled receptor 89B Felis catus
TI:9685 None
   
F1LTD0_RAT
RGD»
1.0
Gpr89b G protein-coupled receptor 89B Rattus norvegicus
TI:10116 None
   
F6ZU15_ORNAN
Ensembl»
0.0
GPR89B G protein-coupled receptor 89B Ornithorhynchus anatinus
TI:9258 None
   
G1KPD9_ANOCA
Ensembl»
0.0
gpr89b Abscisic acid G-protein
coupled receptor-like domain-containing protein		 Anolis carolinensis
TI:28377 None
   
H2MUL5_ORYLA
Ensembl»
0.0
GPR89B G protein-coupled receptor 89B Oryzias latipes
TI:8090 None
   
M1BGR9_SOLTU
EnsemblPlants»
0.0
Protein GPR89A Solanum tuberosum
TI:4113 None 		     
M1BGS0_SOLTU
EnsemblPlants»
0.0
Protein GPR89A Solanum tuberosum
TI:4113 None
   
M4E153_BRACM
EnsemblPlants»
0.0
Abscisic acid G-protein
coupled receptor-like domain-containing protein		 Brassica campestris
TI:3711 None