Collated Gene Ontology terms

Biological process: methyltransferase activity(2017, 2018, 2025) protein-lysine N-methyltransferase activity(2017, 2018, 2023, 2025) transferase activity(2025) S-adenosylmethionine-dependent methyltransferase activity(2025) catalytic activity(2025) lysine N-methyltransferase activity(2017, 2025) hydrolase activity(2025) metalloendopeptidase activity(2025) protein-L-histidine N-tele-methyltransferase activity(2025) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen(2025)
oxidoreductase activity2025 monooxygenase activity2025 metal ion binding2025 iron ion binding2025 heme binding2025

Molecular function: methylation2025 protein methylation2017 peptidyl-lysine trimethylation2017 peptidyl-lysine monomethylation2017 peptidyl-lysine dimethylation2017 tricarboxylic acid cycle2025

Cellular component: mitochondrion2018, 2021, 2024, 2025 cytoplasm2017, 2021, 2025 nucleus2021, 2025 cytosol2024, 2025 chloroplast2018 nucleoplasm2017 endoplasmic reticulum membrane2025 axoneme2017 plasma membrane2018 nuclear lumen2025
mitochondrial matrix2023 Golgi apparatus2018

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 8/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 4/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 39/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
EFNMT_HUMAN
Ensembl»
1.3
METTL13 eEF1A lysine and N-terminal methyltransferase (eEF1A-KNMT) (Methyltransferase-like protein 13) [Includes:
eEF1A lysine methyltransferase (EC 2.1.1.-); eEF1A N-terminal methyltransferase (EC 2.1.1.-)]		 Homo sapiens
TI:9606 None
 
EFNMT_MOUSE
Ensembl»
1.0
Mettl13 eEF1A lysine and N-terminal methyltransferase (eEF1A-KNMT) (Methyltransferase-like protein 13) [Includes:
eEF1A lysine methyltransferase (EC 2.1.1.-); eEF1A N-terminal methyltransferase (EC 2.1.1.-)]		 Mus musculus
TI:10090 None
 
Q9T0K4_ARATH
TAIR»
0.5
At4g13330 At4g13330 (S-adenosyl-L-methionine-dependent
methyltransferases superfamily protein)		 Arabidopsis thaliana
TI:3702 None
 
EFMT4_HUMAN
Ensembl»
2.1
EEF1AKMT4 EEF1A lysine methyltransferase 4 (EC 2.1.1.-) Homo sapiens
TI:9606 None
 
CSKMT_HUMAN
Ensembl»
7.1
CSKMT Citrate synthase-lysine N-methyltransferase CSKMT, mitochondrial (CS-KMT)
(EC 2.1.1.-) (Methyltransferase-like protein 12, mitochondrial)		 Homo sapiens
TI:9606 None
 
EFMT4_MOUSE
Ensembl»
2.5
Eef1akmt4 EEF1A lysine methyltransferase 4 (EC 2.1.1.-) Mus musculus
TI:10090 None
 
Q8VYT6_ARATH
TAIR»
0.5
At2g31740 S-adenosyl-L-methionine-dependent methyltransferases
superfamily protein		 Arabidopsis thaliana
TI:3702 None
 
Q6ID86_ARATH
TAIR»
0.5
At4g34360 EEF1A lysine methyltransferase 4 Arabidopsis thaliana
TI:3702 None
 
Q8RXT8_ARATH
TAIR»
0.5
At3g60910 S-adenosyl-L-methionine-dependent methyltransferases
superfamily protein		 Arabidopsis thaliana
TI:3702 None
 
Q949P5_ARATH
TAIR»
0.0
At3g17365 S-adenosyl-L-methionine-dependent methyltransferases
superfamily protein		 Arabidopsis thaliana
TI:3702 None
 
EFNMT_DANRE
ZFIN»
0.5
mettl13 eEF1A lysine and N-terminal methyltransferase (Methyltransferase-like protein 13) [Includes:
eEF1A lysine methyltransferase (EC 2.1.1.-); eEF1A N-terminal methyltransferase (EC 2.1.1.-)]		 Danio rerio
TI:7955 None
 
EFNMT_DROME
FlyBase»
1.0
CG2614 eEF1A lysine and N-terminal methyltransferase homolog [Includes: eEF1A lysine
methyltransferase homolog (EC 2.1.1.-); eEF1A N-terminal methyltransferase homolog (EC 2.1.1.-)]		 Drosophila melanogaster
TI:7227 None
 
Q9LU07_ARATH
TAIR»
0.5
At5g44590 S-adenosyl-L-methionine-dependent methyltransferases
superfamily protein		 Arabidopsis thaliana
TI:3702 None
 
CSKMT_DANRE
ZFIN»
3.5
cskmt Citrate synthase-lysine N-methyltransferase CSKMT, mitochondrial (CS-KMT)
(EC 2.1.1.-) (Methyltransferase-like protein 12, mitochondrial)		 Danio rerio
TI:7955 None
 
F4KAB4_ARATH
TAIR»
0.5
At5g44600 S-adenosyl-L-methionine-dependent methyltransferases
superfamily protein		 Arabidopsis thaliana
TI:3702 None
 
Q17539_CAEEL
WormBase»
1.3
metl-13 Methyltransferase domain-containing protein Caenorhabditis elegans
TI:6239 None
 
Q54SL7_DICDI
dictyBase»
0.5
DDB_G0282393 Methyltransferase type
11 domain-containing protein		 Dictyostelium discoideum
TI:44689 None
 
Q54VU9_DICDI
dictyBase»
0.5
DDB_G0280123 Methyltransferase domain-containing protein Dictyostelium discoideum
TI:44689 None
 
Q564W8_CAEEL
WormBase»
0.5
C17E4.11 CELE_C17E4.11 Methyltransferase domain-containing protein Caenorhabditis elegans
TI:6239 None
 
A0A8I5ZV13_RAT
RGD»
1.0
Mettl13 eEF1A lysine and N-terminal
methyltransferase (Methyltransferase-like protein 13)		 Rattus norvegicus
TI:10116 None
   
A0A8V0YJG7_CHICK
Ensembl»
0.5
LOC431092 EEF1A lysine methyltransferase 4 Gallus gallus
TI:9031 None
   
A0A8V0YTM9_CHICK
Ensembl»
0.5
METTL13 eEF1A lysine and N-terminal
methyltransferase (Methyltransferase-like protein 13)		 Gallus gallus
TI:9031 None
   
A0AA52KVL1_DANRE
ZFIN»
0.0
ece2a EEF1A lysine methyltransferase 4 isoform X1 Danio rerio
TI:7955 None
   
D4ADU7_RAT
RGD»
1.5
Eef1akmt4 EEF1A lysine methyltransferase 4 Rattus norvegicus
TI:10116 None