Collated Gene Ontology terms

Biological process: L-methionine-(R)-S-oxide reductase activity(2016, 2023, 2024) oxidoreductase activity(2024) protein phosphatase activator activity(2023) protein homodimerization activity(2016) phosphoprotein phosphatase activity(2024)

Molecular function: regulation of phosphoprotein phosphatase activity2024 TOR signaling2009, 2018, 2022, 2024 DNA damage checkpoint signaling2010, 2015, 2024 negative regulation of phosphoprotein phosphatase activity2010, 2024 cellular response to oxidative stress2013, 2024 negative regulation of TORC1 signaling2021, 2024 negative regulation of apoptotic process2012, 2024 chordate embryonic development2012, 2024 negative regulation of signal transduction2024 regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus2016
protein import into mitochondrial matrix2021 protein dephosphorylation2024 cell redox homeostasis2021

Cellular component: cytosol2009, 2014, 2018, 2021, 2024 cytoplasm2015, 2017, 2018, 2024 nucleus2009, 2018, 2024 membrane2024

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 13/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 3/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 37/39 
Archea: 0/8 
Bacteria: 16/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
F1QRY4_DANRE
ZFIN»
2.1
zgc:66327 TIP41-like protein Danio rerio
TI:7955 None
 
FRMSR_YEAST
SGD»
2.1
YKL069W Free methionine-R-sulfoxide reductase (fRMsr) (EC
1.8.4.14) (GAF domain-containing protein YKL069W)		 Saccharomyces cerevisiae
TI:4932 None
 
MSRC_ECOLI
EnsemblBacteria»
2.1
msrC Free methionine-R-sulfoxide reductase
(fRMsr) (EC 1.8.4.14)		 Escherichia coli
TI:562 None
 
TIPRL_HUMAN
Ensembl»
2.1
TIPRL TIP41-like protein (Putative MAPK-activating protein
PM10) (Type 2A-interacting protein) (TIP)		 Homo sapiens
TI:9606 None
 
TIP41_YEAST
SGD»
1.3
TIP41 Type 2A phosphatase activator TIP41 (PP2A
phosphatase activator TIP41) (TAP42-interacting protein 1)		 Saccharomyces cerevisiae
TI:4932 None
 
Q9W5W6_DROME
FlyBase»
1.0
Dmel\CG9578 TIP41-like protein Drosophila melanogaster
TI:7227 None
 
TIP41_SCHPO
PomBase»
1.0
tip41 Type 2A phosphatase activator
tip41 (PP2A phosphatase activator tip41)		 Schizosaccharomyces pombe
TI:4896 None
 
TIPRL_RAT
RGD»
1.0
Tiprl TIP41-like protein Rattus norvegicus
TI:10116 None
 
TIPRL_ARATH
TAIR»
0.8
TIP41L TIP41-like protein Arabidopsis thaliana
TI:3702 None
 
GAFA_DICDI
dictyBase»
0.5
gafA GAF domain-containing protein A Dictyostelium discoideum
TI:44689 None
 
TIPRL_CAEEL
WormBase»
0.5
C02C2.6 ZK688.9 TIP41-like protein Caenorhabditis elegans
TI:6239 None
 
TIPRL_DICDI
dictyBase»
0.5
tiprl TIP41-like protein Dictyostelium discoideum
TI:44689 None
 
A0A022RC49_ERYGU
EnsemblFungi»
0.0
MIMGU_mgv1a011328mg TIP41-like protein Erythranthe guttata
TI:4155 None
 
A0A061E179_THECC
EnsemblPlants»
0.0
TCM_046718 TIP41-like family protein Theobroma cacao
TI:3641 None
 
A0A067DYL9_CITSI
Ensembl»
0.0
CISIN_1g022343mg TIP41-like protein Citrus sinensis
TI:2711 None
 
A0A072VQH6_MEDTR
EnsemblPlants»
0.0
25485370 Type 2A phosphatase activator TIP41, putative Medicago truncatula
TI:3880 None
 
A0A078IHH3_BRANA
EnsemblPlants»
0.0
BnaC03g45080D BnaC03g45080D protein Brassica napus
TI:3708 None
 
A0A0A0K6E3_CUCSA
EnsemblPlants»
0.0
Csa_7G071610 TIP41-like protein Cucumis sativus
TI:3659 None
 
A0A0K9PZZ5_ZOSMR
EnsemblPlants»
0.0
ZOSMA_125G00720 TIP41-like protein Zostera marina
TI:29655 None
 
A0A1D8PNZ9_CANAL
EnsemblFungi»
0.0
TIP41 Tip41p Candida albicans
TI:5476 None
 
A0A1D8PPZ9_CANAL
EnsemblFungi»
0.0
CAALFM_C602800WA orf19.12999 L-methionine (R)-S-oxide reductase Candida albicans
TI:5476 None
 
A0A1L8GEC0_XENLA
Xenbase»
0.0
tiprl.S TIP41-like protein Xenopus laevis
TI:8355 None
   
A0A1S4AQK6_TOBAC
EnsemblFungi»
0.0
LOC107800141 TIP41-like protein Nicotiana tabacum
TI:4097 None
   
A0A1S4BEB5_TOBAC
EnsemblFungi»
0.0
LOC107807353 TIP41-like protein Nicotiana tabacum
TI:4097 None
   
A0A1S4BUH2_TOBAC
EnsemblFungi»
0.0
LOC107812027 TIP41-like protein isoform X1 Nicotiana tabacum
TI:4097 None
   
A0A1U8B5K7_NELNU
EnsemblBacteria»
0.0
LOC104607481 TIP41-like protein isoform X5 Nelumbo nucifera
TI:4432 None
   
A0A1U8BJ98_NELNU
EnsemblBacteria»
0.0
LOC104611680 TIP41-like protein Nelumbo nucifera
TI:4432 None
 
A0A1U8E835_CAPAN
EnsemblPlants»
0.0
T459_32204 TIP41-like protein Capsicum annuum
TI:4072 None
 
A0A1U8KK07_GOSHI
Ensembl»
0.0
LOC107916532 TIP41-like protein Gossypium hirsutum
TI:3635 None
   
A0A1U8MJH8_GOSHI
Ensembl»
0.0
LOC107938344 TIP41-like protein Gossypium hirsutum
TI:3635 None
   
A0A1Y1HYX7_KLENI
EnsemblPlants»
0.0
KFL_001010260 TIP41-like protein Klebsormidium nitens
TI:105231 None
 
A0A251N0Q3_PRUPE
EnsemblPlants»
0.0
PRUPE_8G137600 TIP41-like protein Prunus persica
TI:3760 None
 
A0A251UZ08_HELAN
EnsemblPlants»
0.0
HannXRQ_Chr04g0105981 HanXRQr2_Chr16g0752201 Putative TIP41-like family
protein (TIP41-like protein)		 Helianthus annuus
TI:4232 None
 
A0A2C9VJ23_MANES
EnsemblPlants»
0.0
MANES_07G066500 TIP41-like protein Manihot esculenta
TI:3983 None
 
A0A2I2UU58_FELCA
Ensembl»
0.0
TIPRL TIP41-like protein Felis catus
TI:9685 None
 
A0A2I3TJY1_PANTR
Ensembl»
0.0
TIPRL TIP41-like protein Pan troglodytes
TI:9598 None
 
A0A2I4DQI4_JUGRE
EnsemblPlants»
0.0
LOC108982471 TIP41-like protein Juglans regia
TI:51240 None
 
A0A2I4F7Y7_JUGRE
EnsemblPlants»
0.0
LOC108996357 TIP41-like protein Juglans regia
TI:51240 None
 
A0A2I4FTV9_JUGRE
EnsemblPlants»
0.0
LOC109001995 Uncharacterized protein LOC109001995 Juglans regia
TI:51240 None
 
A0A2K1Z5B4_POPTR
EnsemblPlants»
0.0
POPTR_009G093200 TIP41-like family protein Populus trichocarpa
TI:3694 None
 
A0A2K3CR83_CHLRE
EnsemblPlants»
0.0
CHLRE_17g734150v5 TIP41-like protein Chlamydomonas reinhardtii
TI:3055 None
 
A0A2K3DL01_CHLRE
EnsemblPlants»
0.0
CHLRE_07g347200v5 GAF domain-containing protein Chlamydomonas reinhardtii
TI:3055 None
 
A0A2R6WRF9_MARPO
EnsemblPlants»
0.0
MARPO_0064s0080 TIP41-like protein Marchantia polymorpha
TI:3197 None
 
A0A2U2H1L2_YERPE
EnsemblBacteria»
0.0
YPO1703 GAF domain-containing protein Yersinia pestis
TI:632 None 		 
 
A0A3B6KN17_WHEAT
EnsemblPlants»
0.0
CFC21_067763 TIP41-like protein Triticum aestivum
TI:4565 None
 
A0A3B6LTU5_WHEAT
EnsemblPlants»
0.0
CFC21_073634 TIP41-like protein Triticum aestivum
TI:4565 None
 
A0A3B6MWW8_WHEAT
EnsemblPlants»
0.0
CFC21_079603 TIP41-like protein Triticum aestivum
TI:4565 None
 
A0A3Q1MI24_BOVIN
Ensembl»
0.0
TIPRL TIP41-like protein Bos taurus
TI:9913 None
   
A0A3Q7ES83_SOLLC
EnsemblPlants»
0.0
Uncharacterized protein Solanum lycopersicum
TI:4081 None
   
A0A3Q7JB80_SOLLC
EnsemblPlants»
0.0
TIP41-like protein Solanum lycopersicum
TI:4081 None
   
A0A4X1V4M0_PIG
Ensembl»
0.0
TIPRL TIP41-like protein Sus scrofa
TI:9823 None
 
A0A5F7ZSY3_MACMU
Ensembl»
0.0
TIP41-like protein Macaca mulatta
TI:9544 None
   
A0A6I8MX73_ORNAN
Ensembl»
0.0
TIPRL TIP41-like protein Ornithorhynchus anatinus
TI:9258 None
   
A0A7M7PFV2_STRPU
EnsemblMetazoa»
0.0
TIP41-like protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A804JPI3_MUSAM
EnsemblPlants»
0.0
103990104 (wild Malaysian banana) hypothetical protein Musa acuminata
TI:4641 None
 
A0A8I7B9W0_HORVV
EnsemblPlants»
0.0
TIP41-like protein Hordeum vulgare
TI:4513 None
   
A0A8J8YS46_MAIZE
EnsemblPlants»
0.0
100278962 TIP41-like family protein Zea mays
TI:4577 None
 
A0A8V0XU62_CHICK
Ensembl»
0.0
TIPRL TIP41-like protein Gallus gallus
TI:9031 None
   
A0A9J7LQL2_BRAFL
CTD»
0.0
LOC118422827 TIP41-like protein Branchiostoma floridae
TI:7739 None
   
A0CK65_PARTE
EnsemblProtists»
0.0
GSPATT00000895001 Chromosome undetermined scaffold_2,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None
 
A0E5X8_PARTE
EnsemblProtists»
0.0
GSPATT00003558001 Chromosome undetermined scaffold_8,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None
 
A2DKH2_TRIV3
VEuPathDB»
0.0
TVAG_190440 UPF0067 protein yebR, putative Trichomonas vaginalis
TI:5722 None
 
A5I5Z2_CLOBH
Ensembl»
0.0
CBO2908 Signaling protein Clostridium botulinum
TI:1491 None
 
A7ETJ8_SCLS1
VEuPathDB»
0.0
SS1G_08654 TipA protein Sclerotinia sclerotiorum
TI:5180 None
 
A7EYD5_SCLS1
EnsemblFungi»
0.0
SS1G_10350 GAF domain-containing protein Sclerotinia sclerotiorum
TI:5180 None
 
A7RPF4_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g232080 TIP41-like protein Nematostella vectensis
TI:45351 None
 
A8XF47_CAEBR
WormBase»
0.0
CBG12266 CBG_12266 TIP41-like protein Caenorhabditis briggsae
TI:6238 None
 
A8XF50_CAEBR
WormBase»
0.0
CBG12269 CBG_12269 TIP41-like protein Caenorhabditis briggsae
TI:6238 None
 
A9SD21_PHYPA
EnsemblPlants»
0.0
PHYPA_014079 TIP41-like protein Physcomitrium patens
TI:3218 None
 
A9URC8_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_6025 TIP41-like protein Monosiga brevicollis
TI:81824 None
 
B3RY27_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_56416 TIP41-like protein Trichoplax adhaerens
TI:10228 None
 
B6JZV2_SCHJY
EnsemblFungi»
0.0
SJAG_01142 TIP41-like type 2a phosphatase regulator Tip41 Schizosaccharomyces japonicus
TI:4897 None
 
B7P1M3_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW015580 TIP41-like protein Ixodes scapularis
TI:6945 None
 
B9SNA2_RICCO
EnsemblBacteria»
0.0
RCOM_0174260 Type 2A phosphatase activator TIP41, putative Ricinus communis
TI:3988 None
 
C5X056_SORBI
EnsemblPlants»
0.0
SORBI_3001G082100 TIP41-like protein Sorghum bicolor
TI:4558 None
 
C6T769_SOYBN
EnsemblPlants»
0.0
100811660 TIP41-like protein Glycine max
TI:3847 None
 
C6TMY7_SOYBN
EnsemblPlants»
0.0
100815886 TIP41-like protein Glycine max
TI:3847 None
 
C8V089_EMENI
EnsemblFungi»
0.0
ANIA_05814 TipA protein Emericella nidulans
TI:162425 None
 
C8VC25_EMENI
EnsemblFungi»
0.0
ANIA_07668 GAF domain nucleotide-binding
protein (AFU_orthologue AFUA_2G01360)		 Emericella nidulans
TI:162425 None
 
D1ZZJ5_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_07443 TIP41-like protein Tribolium castaneum
TI:7070 None
 
D7SXV6_VITVI
EnsemblPlants»
0.0
VIT_03s0091g00270 TIP41-like protein Vitis vinifera
TI:29760 None
 
D7TSM0_VITVI
EnsemblPlants»
0.0
VIT_14s0006g00710 Secreted protein Vitis vinifera
TI:29760 None
 
D7UDZ0_VITVI
EnsemblPlants»
0.0
VIT_00s0192g00030 Secreted protein Vitis vinifera
TI:29760 None
 
D8QUM6_SELML
EnsemblPlants»
0.0
SELMODRAFT_78902 TIP41-like protein Selaginella moellendorffii
TI:88036 None
 
D8T1D9_SELML
EnsemblPlants»
0.0
SELMODRAFT_129839 TIP41-like protein Selaginella moellendorffii
TI:88036 None
 
E9GEG4_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_302576 TIP41-like protein Daphnia pulex
TI:6669 None
 
F0ZA56_DICPU
EnsemblProtists»
0.0
DICPUDRAFT_86195 TIP41-like protein Dictyostelium purpureum
TI:5786 None
 
F4NRJ5_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_18163 TIP41-like protein Batrachochytrium dendrobatidis
TI:109871 None
 
F4P3T6_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_6474 GAF domain-containing protein Batrachochytrium dendrobatidis
TI:109871 None
 
F6HWN4_VITVI
EnsemblPlants»
0.0
VIT_00s0183g00030 TIP41-like protein Vitis vinifera
TI:29760 None
 
F6ZBY5_CIOIN
Ensembl»
0.0
LOC100182021 TIP41-like protein Ciona intestinalis
TI:7719 None
 
F7ABT9_MONDO
Ensembl»
0.0
TIP41-like protein Monodelphis domestica
TI:13616 None
   
F7E1Y1_MONDO
Ensembl»
0.0
TIP41-like protein Monodelphis domestica
TI:13616 None
   
G1KKH2_ANOCA
Ensembl»
0.0
TIPRL TIP41-like protein Anolis carolinensis
TI:28377 None
   
G3RB38_GORGO
Ensembl»
0.0
TIPRL TIP41-like protein Gorilla gorilla
TI:9593 None
 
H2LLK9_ORYLA
Ensembl»
0.0
tiprl TIP41-like protein Oryzias latipes
TI:8090 None
   
H3GK15_PHYRM
EnsemblProtists»
0.0
GAF domain-containing protein Phytophthora ramorum
TI:164328 None
 
H3HEG3_PHYRM
EnsemblProtists»
0.0
Tyrosine specific protein
phosphatases domain-containing protein		 Phytophthora ramorum
TI:164328 None
 
H9ENJ3_MACMU
Ensembl»
0.0
TIPRL TIP41-like protein Macaca mulatta
TI:9544 None
 
I1GN21_BRADI
EnsemblPlants»
0.0
100829541 TIP41-like protein Brachypodium distachyon
TI:15368 None
 
K4ADC7_SETIT
EnsemblPlants»
0.0
101764446 TIP41-like protein Setaria italica
TI:4555 None
 
M1C4S3_SOLTU
EnsemblPlants»
0.0
Type 2A phosphatase activator TIP41 Solanum tuberosum
TI:4113 None
   
M1CF59_SOLTU
EnsemblPlants»
0.0
102597299 Type 2A phosphatase activator TIP41 Solanum tuberosum
TI:4113 None
   
M4D4V9_BRACM
EnsemblPlants»
0.0
TIP41-like protein Brassica campestris
TI:3711 None
   
Q1K867_NEUCR
EnsemblFungi»
0.0
NCU01163 GAF domain nucleotide-binding protein Neurospora crassa
TI:5141 None
 
Q2FXK7_STAA8
EnsemblBacteria»
0.0
SAOUHSC_01828 GAF domain protein Staphylococcus aureus
TI:1280 None
 
Q4QAZ2_LEIMA
EnsemblProtists»
0.0
LMJF_23_1460 GAF domain-containing protein Leishmania major
TI:5664 None
 
Q4WIM1_ASPFU
EnsemblFungi»
0.0
AFUA_2G01360 GAF domain nucleotide-binding protein Aspergillus fumigatus
TI:746128 None
 
Q4X263_ASPFU
EnsemblFungi»
0.0
AFUA_2G07540 TOR signalling pathway protein TipA, putative Aspergillus fumigatus
TI:746128 None
 
Q57VD8_TRYB2
VEuPathDB»
0.0
Tb05.30H13.220 GAF domain-containing protein Trypanosoma brucei
TI:5691 None
 
Q5KA94_CRYNJ
EnsemblFungi»
0.0
CNJ02510 Signal transduction-related protein, putative Cryptococcus neoformans
TI:5207 None
 
Q5TTX3_ANOGA
EnsemblMetazoa»
0.0
1273302 TIP41-like protein Anopheles gambiae
TI:7165 None
 
Q6BFU4_PARTE
EnsemblProtists»
0.0
GSPATT00000227001 PTMB.278 Chromosome undetermined scaffold_1, whole genome
shotgun sequence (TIP41-like protein, putative)		 Paramecium tetraurelia
TI:5888 None
 
Q6C0F3_YARLI
EnsemblFungi»
0.0
YALI0_F25201g YALI0F25201p Yarrowia lipolytica
TI:4952 None
 
Q6CAZ7_YARLI
EnsemblFungi»
0.0
YALI0_C23100g YALI0C23100p Yarrowia lipolytica
TI:4952 None
 
Q754F5_ASHGO
EnsemblFungi»
0.0
AGOS_AFR115W AFR115Wp Ashbya gossypii
TI:33169 None
 
Q75BU7_ASHGO
EnsemblFungi»
0.0
AGOS_ACR174C ACR174Cp Ashbya gossypii
TI:33169 None
 
Q817A6_BACCR
EnsemblBacteria»
0.0
BC_4653 GAF domain-containing proteins Bacillus cereus
TI:1396 None
 
Q8A6R6_BACTN
EnsemblBacteria»
0.0
BT_1810 GAF domain-containing protein Bacteroides thetaiotaomicron
TI:818 None
 
Q8DQA6_STRR6
EnsemblBacteria»
0.0
spr0768 GAF domain-containing protein Streptococcus pneumoniae
TI:1313 None
 
Q8EDY7_SHEON
EnsemblPlants»
0.0
yebR Free methionine-R-sulfoxide reductase
YebR (EC 1.8.4.14)		 Shewanella oneidensis
TI:70863 None
 
Q8PCW5_XANCP
EnsemblBacteria»
0.0
XCC0586 GAF domain-containing protein Xanthomonas campestris
TI:339 None
 
Q8Y6T7_LISMO
EnsemblBacteria»
0.0
lmo1595 Lmo1595 protein Listeria monocytogenes
TI:1639 None
 
Q8ZNZ5_SALTY
EnsemblBacteria»
0.0
yebR GAF domain-containing protein Salmonella typhimurium
TI:28901 None
 
Q94HA2_ORYSJ
EnsemblPlants»
0.0
LOC_Os03g55270 Os03g0760600 Os03g0760600 protein (TIP41-like family protein,
expressed) (cDNA clone:J033131F13, full insert sequence)		 Oryza sativa
TI:4530 None
 
Q9I021_PSEAE
EnsemblBacteria»
0.0
PA2822 GAF domain-containing protein Pseudomonas aeruginosa
TI:287 None
 
Q9JXT9_NEIMB
EnsemblBacteria»
0.0
NMB1886 GAF domain-containing protein Neisseria meningitidis
TI:487 None
 
Q9KRY5_VIBCH
EnsemblBacteria»
0.0
VC_1498 GAF domain-containing protein Vibrio cholerae
TI:666 None
 
Q9WYY9_THEMA
EnsemblBacteria»
0.0
TM_0519 GAF domain-containing protein Thermotoga maritima
TI:2336 None
 
T1FM42_HELRO
EnsemblMetazoa»
0.0
20209891 TIP41-like protein Helobdella robusta
TI:6412 None
 
TIPRL_MOUSE
Ensembl»
0.0
Tiprl TIP41-like protein Mus musculus
TI:10090 None
 
TIPRL_XENLA
Xenbase»
0.0
tiprl TIP41-like protein Xenopus laevis
TI:8355 None
 
TIPRL_XENTR
Xenbase»
0.0
tiprl TIP41-like protein Xenopus tropicalis
TI:8364 None
 
U5GV10_POPTR
EnsemblPlants»
0.0
POPTR_001G298500 TIP41-like family protein Populus trichocarpa
TI:3694 None
 
U9W318_NEUCR
EnsemblFungi»
0.0
NCU00109 TipA protein (TipA protein, variant) Neurospora crassa
TI:5141 None
 
W1NMH3_AMBTC
EnsemblPlants»
0.0
AMTR_s00001p00272840 TIP41-like protein Amborella trichopoda
TI:13333 None
 
W5MCN2_LEPOC
Ensembl»
0.0
TIP41-like protein Lepisosteus oculatus
TI:7918 None
 
YTSP_BACSU
EnsemblBacteria»
0.0
ytsP Protein YtsP Bacillus subtilis
TI:1423 None