Collated Gene Ontology terms

Biological process: hydrolase activity(2025) metal ion binding(2025) phosphoric diester hydrolase activity(2025) GPI-mannose ethanolamine phosphate phosphodiesterase activity(2019, 2025) manganese ion binding(2010) protein serine/threonine phosphatase activity(2020, 2025) exonuclease activity(2025)

Molecular function: GPI anchor biosynthetic process2010, 2015, 2017, 2020, 2021, 2025 endoplasmic reticulum to Golgi vesicle-mediated transport2010, 2013, 2025 vesicle-mediated transport2025 cell division2025 DNA repair2013, 2025

Cellular component: membrane2006, 2025 endoplasmic reticulum2009, 2013, 2017, 2018, 2025 endoplasmic reticulum-Golgi intermediate compartment2025 endoplasmic reticulum-Golgi intermediate compartment membrane2025 endomembrane system2025 cytoplasm2025 Golgi apparatus2011, 2021, 2024, 2025 endoplasmic reticulum exit site2010, 2025 endoplasmic reticulum membrane2017, 2025 trans-Golgi network2021
nucleoplasm2025 endosome2021 Golgi cis cisterna2019

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 36/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
YFH2_SCHPO
PomBase»
1.0
SPAC23A1.02c Uncharacterized protein C23A1.02c Schizosaccharomyces pombe
TI:4896 None
 
YKIC_SCHPO
PomBase»
0.5
SPAC630.12 Uncharacterized protein C630.12 Schizosaccharomyces pombe
TI:4896 None
 
CDC1_YEAST
SGD»
2.9
CDC1 Cell division control protein 1 (EC 3.1.-.-) Saccharomyces cerevisiae
TI:4932 None
 
TED1_YEAST
SGD»
2.1
TED1 Protein TED1 (Trafficking of
EMP24/ERV25-dependent cargo disrupted protein 1)		 Saccharomyces cerevisiae
TI:4932 None
 
MPPE1_RAT
RGD»
2.5
Mppe1 Metallophosphoesterase 1 (EC 3.1.-.-) (Post-GPI
attachment to proteins factor 5)		 Rattus norvegicus
TI:10116 None
 
MPPE1_MOUSE
Ensembl»
2.5
Mppe1 Metallophosphoesterase 1 (EC 3.1.-.-) (Post-GPI
attachment to proteins factor 5)		 Mus musculus
TI:10090 None
 
MPPE1_HUMAN
Ensembl»
2.8
MPPE1 Metallophosphoesterase 1 (EC 3.1.-.-) (Post-GPI
attachment to proteins factor 5)		 Homo sapiens
TI:9606 None
 
A0A8V0XAX1_CHICK
Ensembl»
0.0
MPPE1 Metallophosphoesterase 1 (Post-GPI attachment
to proteins factor 5)		 Gallus gallus
TI:9031 None
   
MPPE1_CHICK
CTD»
2.0
MPPE1 Metallophosphoesterase 1 (EC 3.1.-.-) (Post-GPI
attachment to proteins factor 5)		 Gallus gallus
TI:9031 None
 
A0A0B4LF50_DROME
FlyBase»
1.3
Mppe Metallophosphoesterase, isoform E
(EC 3.-.-.-, EC 3.1.3.16)		 Drosophila melanogaster
TI:7227 None
 
MPPE1_DROME
FlyBase»
1.0
PGAP5 Metallophosphoesterase 1 homolog (EC 3.1.-.-)
(Post-GPI attachment to proteins 5 ortholog)		 Drosophila melanogaster
TI:7227 None
 
Q54X09_DICDI
dictyBase»
0.5
DDB_G0279279 Calcineurin-like phosphoesterase
domain-containing protein		 Dictyostelium discoideum
TI:44689 None
 
MPPE1_DANRE
ZFIN»
2.0
mppe1 Metallophosphoesterase 1 (EC 3.1.-.-) (Post-GPI
attachment to proteins factor 5)		 Danio rerio
TI:7955 None
 
MPPE1_CAEEL
WormBase»
0.0
mppe-1 Metallophosphoesterase 1 homolog (EC 3.1.-.-) Caenorhabditis elegans
TI:6239 None
 
Q23592_CAEEL
WormBase»
0.5
CELE_ZK792.7 ZK792.7 Calcineurin-like phosphoesterase
domain-containing protein		 Caenorhabditis elegans
TI:6239 None
 
A8MQN4_ARATH
TAIR»
0.5
At1g53710 Calcineurin-like metallo-phosphoesterase
superfamily protein		 Arabidopsis thaliana
TI:3702 None