Collated Gene Ontology terms

Biological process: nucleic acid binding(2024) telomerase inhibitor activity(2008, 2009, 2013, 2015, 2017, 2021, 2024) telomerase RNA binding(2009, 2024) protein-containing complex binding(2017, 2024) RNA binding(2004, 2014) enzyme activator activity(2019) DNA binding(2024)

Molecular function: ribosome biogenesis2004, 2024 rRNA processing2024 negative regulation of telomere maintenance via telomerase2013, 2015, 2024 telomere maintenance via telomerase2017, 2024 regulation of ribosome biogenesis2019, 2024 regulation of cell population proliferation2019, 2024 regulation of protein stability2015, 2024 protein localization to nucleolus2015, 2024 protein localization to chromosome, telomeric region2015, 2024 positive regulation of protein localization to nucleolus2015, 2024
negative regulation of protein ubiquitination2015, 2024 negative regulation of G2/M transition of mitotic cell cycle2017, 2024 mitotic metaphase plate congression2009, 2024 ribosomal small subunit biogenesis2013, 2024 hematopoietic progenitor cell differentiation2014, 2024 positive regulation of telomeric DNA binding2015 negative regulation of telomere maintenance via telomere lengthening2015 negative regulation of cell population proliferation2002 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021 maturation of SSU-rRNA2023 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021 box C/D RNA 3'-end processing2013

Cellular component: nucleolus2004, 2008, 2009, 2013, 2015, 2017, 2018, 2019, 2023, 2024 nucleus2009, 2017, 2024 nucleoplasm2013, 2023, 2024 chromosome, telomeric region2016, 2017, 2024 kinetochore2009, 2024 spindle2009, 2024 nuclear chromosome2009, 2024 mitochondrion2023, 2024 chromosome, centromeric region2024 chromosome2024
small-subunit processome2023

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 2/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 38/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 5 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
PINX1_HUMAN
Ensembl»
15.2
PINX1 PIN2/TERF1-interacting telomerase inhibitor 1 (Liver-related putative tumor suppressor)
(Pin2-interacting protein X1) (Protein 67-11-3) (TRF1-interacting protein 1)		 Homo sapiens
TI:9606 None
 
GPTC4_HUMAN
AG»
0.5
GPATCH4 G patch domain-containing protein 4 Homo sapiens
TI:9606 None
 
PINX1_MOUSE
Ensembl»
0.5
Pinx1 PIN2/TERF1-interacting telomerase inhibitor 1 (67-11-3 protein) (LPTS1) (Liver-related
putative tumor suppressor) (Pin2-interacting protein X1) (TRF1-interacting protein 1)		 Mus musculus
TI:10090 None
 
GPDP1_ARATH
TAIR»
1.6
GDP1 G-patch domain-containing protein 1 Arabidopsis thaliana
TI:3702 None
 
GPTC4_MOUSE
Ensembl»
0.8
Gpatch4 G patch domain-containing protein 4 Mus musculus
TI:10090 None
 
PXR1_YEAST
SGD»
6.2
PXR1 Protein PXR1 (G-patch nucleolar
protein) (PinX1-related protein 1)		 Saccharomyces cerevisiae
TI:4932 None
 
TMA23_YEAST
SGD»
0.8
TMA23 Protein TMA23 (23
kDa translation machinery-associated protein)		 Saccharomyces cerevisiae
TI:4932 None
   
A0A0A6YYK5_HUMAN
Ensembl»
0.0
Uncharacterized protein Homo sapiens
TI:9606 None
 
A0A8M9NZA1_DANRE
ZFIN»
0.0
im:7138553 G patch domain-containing 4 (G patch domain-containing protein
4) (G patch domain-containing protein 4 isoform X1)		 Danio rerio
TI:7955 None
 
A1ZBW6_DROME
FlyBase»
0.5
Dmel\CG11180 Uncharacterized protein, isoform A Drosophila melanogaster
TI:7227 None
 
GPTC4_RAT
RGD»
0.5
Gpatch4 G patch domain-containing protein 4 Rattus norvegicus
TI:10116 None
 
PINX1_RAT
RGD»
6.5
Pinx1 PIN2/TERF1-interacting telomerase inhibitor
1 (Pin2-interacting protein X1)		 Rattus norvegicus
TI:10116 None
 
PXR1_SCHPO
PomBase»
1.0
pxr1 Protein pxr1 (PinX1-related protein 1) Schizosaccharomyces pombe
TI:4896 None
 
Q22705_CAEEL
WormBase»
0.5
CELE_T23G7.3 T23G7.3 G-patch domain-containing protein Caenorhabditis elegans
TI:6239 None
 
Q9V9Z8_DROME
FlyBase»
0.0
Dmel\CG15561 G-patch domain-containing protein Drosophila melanogaster
TI:7227 None
 
Y5282_DICDI
dictyBase»
0.0
DDB_G0278987 Uncharacterized G-patch
domain protein DDB_G0278987		 Dictyostelium discoideum
TI:44689 None
 
YLO2_SCHPO
PomBase»
1.0
SPAC1952.02 Uncharacterized protein C1952.02 Schizosaccharomyces pombe
TI:4896 None
   
A0A8M9PH59_DANRE
CTD»
1.3
pinx1 PIN2/TERF1-interacting telomerase inhibitor
1 isoform X1		 Danio rerio
TI:7955 None
   
A0A8V0YA09_CHICK
Ensembl»
0.0
PINX1 PIN2 (TERF1) interacting telomerase inhibitor 1 Gallus gallus
TI:9031 None
   
A0A8V1AC52_CHICK
Ensembl»
0.0
GPATCH4 G patch domain-containing protein 4 Gallus gallus
TI:9031 None