Biological process: mRNA binding^{(2020, 2021, 2024)} second spliceosomal transesterification activity^{(2013, 2024)} RNA binding^{(2014, 2015)} structural constituent of ribosome⁽²⁰²⁴⁾ histone acetyltransferase activity⁽²⁰²⁴⁾ acyltransferase activity⁽²⁰²⁴⁾

Molecular function: mRNA splicing, via spliceosome^{2006, 2010, 2011, 2016, 2019, 2021, 2023, 2024} embryonic brain development^{2021, 2024} mRNA cis splicing, via spliceosome^{2023, 2024} generation of catalytic spliceosome for second transesterification step^{2013, 2016, 2024} mRNA branch site recognition^{2013, 2024} mRNA 3'-splice site recognition^{2013, 2024} mRNA processing²⁰²⁴ cell division²⁰²⁴ RNA splicing²⁰²⁴ RNA splicing, via transesterification reactions^{2007, 2009}
± 7 ribosomal large subunit biogenesis²⁰²¹ mitochondrial translation²⁰²⁴ maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)²⁰²¹ intraciliary transport involved in cilium assembly²⁰²⁴ endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)²⁰²¹ endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)²⁰²¹ chromatin remodeling²⁰²⁴

Cellular component: catalytic step 2 spliceosome^{2010, 2011, 2021, 2024} spliceosomal complex^{2006, 2007, 2013, 2023, 2024} nuclear speck^{2019, 2024} nucleoplasm^{2013, 2018, 2023, 2024} U2-type catalytic step 2 spliceosome^{2018, 2019, 2024} Prp19 complex^{2013, 2016, 2024} post-mRNA release spliceosomal complex^{2016, 2024} nucleus^{2009, 2017, 2024} nuclear periphery^{2016, 2024} ribosome²⁰²⁴
± 10 precatalytic spliceosome²⁰¹⁰ organelle²⁰²⁴ nucleolus²⁰¹⁸ mitochondrial large ribosomal subunit²⁰²⁴ membrane²⁰²⁴ extracellular region²⁰¹⁹ ciliary tip²⁰²⁴ ciliary pocket collar²⁰²⁴ ciliary basal body²⁰²⁴ 9+2 motile cilium²⁰²⁴