Collated Gene Ontology terms

Biological process: diphthine methylesterase activity(2015, 2020, 2022, 2024) hydrolase activity(2024) methyltransferase activity(2024) protein methylesterase activity(2020)

Molecular function: peptidyl-diphthamide biosynthetic process from peptidyl-histidine2010, 2013, 2020, 2022, 2024 methylation2024 endocytic recycling2012, 2013, 2024 rRNA processing2019 protein homooligomerization2024 positive regulation of transcription by RNA polymerase I2019 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021

Cellular component: cytoplasm2013, 2017, 2020, 2022, 2024 endosome2013, 2024 nucleus2009, 2024 cytosol2009, 2014 organelle2024 nucleolus2019 Cul4-RING E3 ubiquitin ligase complex2008

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 2/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 35/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

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Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
A0A1D5P6U5_CHICK
Ensembl»
1.0
DPH7 Diphthamide biosynthesis 7 Gallus gallus
TI:9031 None
   
DPH7_HUMAN
Ensembl»
1.8
DPH7 Diphthine methyltransferase (EC 3.1.1.97) (Diphthamide biosynthesis
protein 7) (WD repeat-containing protein 85)		 Homo sapiens
TI:9606 None
 
Q9W3X3_DROME
FlyBase»
2.0
Dmel\CG3184 GH14157p Drosophila melanogaster
TI:7227 None
 
D4A1S8_RAT
RGD»
2.0
Dph7 Diphthamide biosynthesis 7 Rattus norvegicus
TI:10116 None
   
DPH7_MOUSE
Ensembl»
0.5
Dph7 Diphthine methyltransferase (EC 3.1.1.97) (Diphthamide biosynthesis
protein 7) (DPH7) (WD repeat-containing protein 85)		 Mus musculus
TI:10090 None
 
Q9FM51_ARATH
TAIR»
0.0
MJH22.7 Transducin/WD40 repeat-like superfamily protein Arabidopsis thaliana
TI:3702 None
 
DPH7_YEAST
SGD»
5.0
RRT2 Diphthine methyltransferase (EC 3.1.1.97) (Diphthamide biosynthesis protein 7) (Endosomal
recycling protein 1) (Regulator of rDNA transcription protein 2)		 Saccharomyces cerevisiae
TI:4932 None
 
G5EBG2_CAEEL
WormBase»
1.0
dph-7 WD_REPEATS_REGION domain-containing protein Caenorhabditis elegans
TI:6239 None
 
DPH7_SCHPO
PomBase»
1.5
rrt2 Diphthine methyltransferase (EC 3.1.1.97) (Diphthamide biosynthesis
protein 7) (WD repeat-containing protein rrt2)		 Schizosaccharomyces pombe
TI:4896 None
 
DPH7_DICDI
dictyBase»
1.0
wdr85 Diphthine methyltransferase homolog (EC 3.1.1.97) (Diphthamide biosynthesis
protein 7 homolog) (WD repeat-containing protein 85 homolog)		 Dictyostelium discoideum
TI:44689 None
 
A3KNN6_DANRE
ZFIN»
1.0
zgc:162277 Diphthamide biosynthesis 7 (Diphthine
methyltransferase (EC 3.1.1.97)) (Zgc:162277 protein)		 Danio rerio
TI:7955 None