Collated Gene Ontology terms

Biological process: tRNA (guanine) methyltransferase activity(2013, 2017, 2024) RNA binding(2003, 2024) methyltransferase activity(2024) serine-type endopeptidase activity(2024) microtubule motor activity(2024) microtubule binding(2024) hydrolase activity(2024) cytoskeletal motor activity(2024) RNA methyltransferase activity(2024) ATP binding(2024)

Molecular function: tRNA methylation2013, 2017, 2024 methylation2024 tRNA nucleoside ribose methylation2020, 2024 cellular response to oxidative stress2020, 2024 tRNA processing2024 regulation of transcription by RNA polymerase II2003 proteolysis2024 microtubule-based movement2024 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021
endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021 RNA processing2024

Cellular component: cytoplasm2017, 2018, 2024 ciliary basal body2017 nucleus2003 membrane2024

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 6/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 3/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 35/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
W1NTX8_AMBTC
EnsemblPlants»
0.0
AMTR_s00002p00160160 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Amborella trichopoda
TI:13333 None
 
W1NZF7_AMBTC
EnsemblPlants»
0.0
AMTR_s00002p00162270 Uncharacterized protein Amborella trichopoda
TI:13333 None 		 
 
W1P0A3_AMBTC
EnsemblPlants»
0.0
AMTR_s00002p00163320 Uncharacterized protein Amborella trichopoda
TI:13333 None 		 
 
G1K946_ANOCA
Ensembl»
0.0
TARBP1 TAR (HIV-1) RNA binding protein 1 Anolis carolinensis
TI:28377 None
   
A0A1S4GRB3_ANOGA
EnsemblMetazoa»
0.0
tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Anopheles gambiae
TI:7165 None
 
A0NEI0_ANOGA
EnsemblMetazoa»
0.0
4576628 AGAP005789-PA Anopheles gambiae
TI:7165 None
 
F4JP86_ARATH
TAIR»
0.0
TRM3 tRNA/rRNA methyltransferase
(SpoU) family protein		 Arabidopsis thaliana
TI:3702 None
 
Q75B66_ASHGO
EnsemblFungi»
0.0
AGOS_ADL294C ADL294Cp Ashbya gossypii
TI:33169 None
 
F4P520_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_11794 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Batrachochytrium dendrobatidis
TI:109871 None
 
A0A3Q1MYK3_BOVIN
Ensembl»
0.0
TARBP1 TAR (HIV-1) RNA binding protein 1 Bos taurus
TI:9913 None
   
A0A0Q3K2U5_BRADI
EnsemblPlants»
0.0
100841607 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Brachypodium distachyon
TI:15368 None
 
A0A9J7MNG7_BRAFL
CTD»
0.0
LOC118413789 Probable methyltransferase TARBP1 isoform X1
(Probable methyltransferase TARBP1 isoform X2)		 Branchiostoma floridae
TI:7739 None
   
A0A078H1W0_BRANA
EnsemblPlants»
0.0
BnaC05g21790D BnaC05g21790D protein Brassica napus
TI:3708 None 		 
 
A0A078HL70_BRANA
EnsemblPlants»
0.0
BnaC01g10200D BnaC01g10200D protein Brassica napus
TI:3708 None
 
A0A078ITU2_BRANA
EnsemblPlants»
0.0
BnaC01g42720D (rape) hypothetical
protein (BnaC01g42720D protein)		 Brassica napus
TI:3708 None 		 
 
M4FGE0_BRACM
EnsemblPlants»
0.0
tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Brassica campestris
TI:3711 None
   
A8XCI8_CAEBR
WormBase»
0.0
CBG11131 CBG_11131 Protein CBG11131 Caenorhabditis briggsae
TI:6238 None 		 
 
Q22484_CAEEL
WormBase»
1.0
CELE_T14B4.1 T14B4.1 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Caenorhabditis elegans
TI:6239 None
 
A0A1D8PLX4_CANAL
EnsemblFungi»
0.0
CAALFM_C403830WA orf19.12505 tRNA (Guanosine(18)-2'-O)-methyltransferase Candida albicans
TI:5476 None
 
A0A8I3MRW2_CANLF
Ensembl»
0.0
TARBP1 TAR (HIV-1) RNA binding protein 1 Canis lupus
TI:9612 None
   
A0A1U8GPN1_CAPAN
EnsemblPlants»
0.0
T459_00734 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Capsicum annuum
TI:4072 None
 
A0A2G3AN67_CAPAN
EnsemblPlants»
0.0
T459_03558 Uncharacterized protein Capsicum annuum
TI:4072 None 		 
 
A0A2K3CWK1_CHLRE
EnsemblPlants»
0.0
CHLRE_15g637350v5 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Chlamydomonas reinhardtii
TI:3055 None
 
A0A2K3E6I5_CHLRE
EnsemblPlants»
0.0
CHLRE_01g027350v5 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Chlamydomonas reinhardtii
TI:3055 None
 
F6YVG2_CIOIN
Ensembl»
0.0
tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Ciona intestinalis
TI:7719 None
 
A0A067ET04_CITSI
Ensembl»
0.0
CISIN_1g000208mg tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Citrus sinensis
TI:2711 None
 
A0A0A0L1E9_CUCSA
EnsemblPlants»
0.0
Csa_3G017140 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Cucumis sativus
TI:3659 None
 
A0A8M1QV42_DANRE
CTD»
0.0
si:dkey-85a20.4 Probable methyltransferase TARBP1 isoform X1
(Probable methyltransferase TARBP1 isoform X2)		 Danio rerio
TI:7955 None
   
E9H6E6_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_58639 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Daphnia pulex
TI:6669 None
 
F0ZGV1_DICPU
EnsemblProtists»
0.0
DICPUDRAFT_14626 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Dictyostelium purpureum
TI:5786 None
 
F0ZMW8_DICPU
EnsemblProtists»
0.0
DICPUDRAFT_153035 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Dictyostelium purpureum
TI:5786 None
 
Q54N52_DICDI
dictyBase»
1.0
DDB_G0285499 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Dictyostelium discoideum
TI:44689 None
 
Q54XF8_DICDI
dictyBase»
1.0
DG2033 tRNA/rRNA methyltransferase SpoU family protein Dictyostelium discoideum
TI:44689 None
 
Q9VD22_DROME
FlyBase»
1.0
Dmel\CG18596 LP02352p Drosophila melanogaster
TI:7227 None
 
F7C877_HORSE
Ensembl»
0.0
TARBP1 TAR (HIV-1) RNA binding protein 1 Equus caballus
TI:9796 None
   
A0A022QQ55_ERYGU
EnsemblFungi»
0.0
MIMGU_mgv11b020612mg Uncharacterized protein Erythranthe guttata
TI:4155 None 		 
 
A0A022QWL0_ERYGU
EnsemblFungi»
0.0
MIMGU_mgv1a019787mg tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Erythranthe guttata
TI:4155 None
 
A0A022RK75_ERYGU
EnsemblFungi»
0.0
MIMGU_mgv1a022707mg Uncharacterized protein Erythranthe guttata
TI:4155 None 		 
 
A0A022RLE1_ERYGU
EnsemblFungi»
0.0
MIMGU_mgv11b014887mg tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Erythranthe guttata
TI:4155 None
 
A0A022RM15_ERYGU
EnsemblFungi»
0.0
MIMGU_mgv1a019664mg Uncharacterized protein Erythranthe guttata
TI:4155 None 		 
 
A0A5F5XY82_FELCA
Ensembl»
0.0
TARBP1 TAR (HIV-1) RNA binding protein 1 Felis catus
TI:9685 None
 
A0A8V0XZY1_CHICK
Ensembl»
0.0
TARBP1 TAR (HIV-1) RNA binding protein 1 Gallus gallus
TI:9031 None
   
A0A644F2L6_GIAIC
EnsemblProtists»
0.0
GL50803_0032741 tRNA guanosine-2'-O-methyltransferase Giardia intestinalis
TI:5741 None
 
A0A0R0FD66_SOYBN
EnsemblPlants»
0.0
100809637 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Glycine max
TI:3847 None
 
G3RWS0_GORGO
Ensembl»
0.0
TARBP1 TAR (HIV-1) RNA binding protein 1 Gorilla gorilla
TI:9593 None
 
A0A1U8KW04_GOSHI
Ensembl»
0.0
LOC107921250 Uncharacterized protein LOC107921250 isoform X1 Gossypium hirsutum
TI:3635 None 		     
A0A1U8NC75_GOSHI
Ensembl»
0.0
LOC107946698 Uncharacterized protein LOC107946698 isoform X1 Gossypium hirsutum
TI:3635 None
   
A0A251RWX6_HELAN
EnsemblPlants»
0.0
HannXRQ_Chr16g0504541 Putative tRNA/rRNA methyltransferase
(SpoU) family protein		 Helianthus annuus
TI:4232 None
 
A0A9K3DSY1_HELAN
EnsemblPlants»
0.0
HanXRQr2_Chr16g0744051 Uncharacterized protein Helianthus annuus
TI:4232 None 		 
 
T1FZ95_HELRO
EnsemblMetazoa»
0.0
20214143 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Helobdella robusta
TI:6412 None
 
TARB1_HUMAN
Ensembl»
2.8
TARBP1 Probable methyltransferase TARBP1 (EC 2.1.1.-) (TAR RNA-binding protein
1) (TAR RNA-binding protein of 185 kDa) (TRP-185)		 Homo sapiens
TI:9606 None
 
A0A8I6XH11_HORVV
EnsemblPlants»
0.0
tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Hordeum vulgare
TI:4513 None
   
B7P9A4_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW002073 Uncharacterized protein Ixodes scapularis
TI:6945 None 		 
 
B7P9A5_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW002074 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Ixodes scapularis
TI:6945 None
 
A0A6P9E657_JUGRE
EnsemblPlants»
0.0
LOC108984987 Uncharacterized protein LOC108984987 Juglans regia
TI:51240 None 		     
A0A6P9E6Y5_JUGRE
EnsemblPlants»
0.0
LOC108983692 Uncharacterized protein LOC108983692 Juglans regia
TI:51240 None
   
A0A1Y1IRH0_KLENI
EnsemblPlants»
0.0
KFL_007680030 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Klebsormidium nitens
TI:105231 None
 
Q4Q510_LEIMA
EnsemblProtists»
0.0
LMJF_32_2650 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Leishmania major
TI:5664 None
 
W5NH85_LEPOC
Ensembl»
0.0
Octopamine receptor 2-like Lepisosteus oculatus
TI:7918 None
 
F7EZY1_MACMU
Ensembl»
0.0
TARBP1 TAR (HIV-1) RNA binding protein 1 Macaca mulatta
TI:9544 None
   
A0A2C9WJ05_MANES
EnsemblPlants»
0.0
MANES_01G088800 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Manihot esculenta
TI:3983 None
 
A0A2R6WDK5_MARPO
EnsemblPlants»
0.0
MARPO_0105s0045 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Marchantia polymorpha
TI:3197 None
 
A0A072UPJ3_MEDTR
EnsemblPlants»
0.0
25493589 Putative tRNA (Guanosine(18)-2'-O)-methyltransferase (EC 2.1.1.34)
(tRNA/rRNA methyltransferase SpoU family protein)		 Medicago truncatula
TI:3880 None
 
F7FTF7_MONDO
Ensembl»
0.0
TARBP1 TAR (HIV-1) RNA binding protein 1 Monodelphis domestica
TI:13616 None
   
A9US19_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_22775 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Monosiga brevicollis
TI:81824 None
 
E9Q368_MOUSE
Ensembl»
0.0
Tarbp1 TAR RNA binding protein 1 Mus musculus
TI:10090 None
   
A0A804L2L7_MUSAM
EnsemblPlants»
0.0
GSMUA_25170.1 (wild Malaysian banana) hypothetical protein Musa acuminata
TI:4641 None
 
A0A1U8B188_NELNU
EnsemblBacteria»
0.0
LOC104609816 Uncharacterized protein LOC104609816 isoform X3 Nelumbo nucifera
TI:4432 None
   
A7RT83_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g92540 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Nematostella vectensis
TI:45351 None
 
A0A1S3XQF0_TOBAC
EnsemblFungi»
0.0
LOC107767630 Uncharacterized protein LOC107767630 Nicotiana tabacum
TI:4097 None
   
A0A1S3Z8K2_TOBAC
EnsemblFungi»
0.0
LOC107784157 Uncharacterized protein LOC107784157 Nicotiana tabacum
TI:4097 None 		     
A0A1S4AJR1_TOBAC
EnsemblFungi»
0.0
LOC107798414 Uncharacterized protein LOC107798414 isoform X1 Nicotiana tabacum
TI:4097 None 		     
A0A1S4C576_TOBAC
EnsemblFungi»
0.0
LOC107815307 Uncharacterized protein LOC107815307 Nicotiana tabacum
TI:4097 None
   
A0A1S4C586_TOBAC
EnsemblFungi»
0.0
LOC107815308 Uncharacterized protein LOC107815308 isoform X1 Nicotiana tabacum
TI:4097 None
   
A0A6I8N1J2_ORNAN
Ensembl»
0.0
tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Ornithorhynchus anatinus
TI:9258 None
   
Q0DW28_ORYSJ
EnsemblPlants»
0.0
Os03g0100500 Os03g0100500 protein Oryza sativa
TI:4530 None
 
Q33B43_ORYSJ
EnsemblPlants»
0.0
LOC_Os10g05290 Os10g0142900 Os10g0142900 protein (cDNA clone:J013055N04, full
insert sequence) (tRNA/rRNA methyltransferase, putative, expressed)		 Oryza sativa
TI:4530 None
 
H2M436_ORYLA
Ensembl»
0.0
tarbp1 TAR (HIV-1) RNA binding protein 1 Oryzias latipes
TI:8090 None
   
H2Q1D3_PANTR
Ensembl»
0.0
TARBP1 TAR (HIV-1) RNA binding protein 1 Pan troglodytes
TI:9598 None
 
A0CN46_PARTE
EnsemblProtists»
0.0
GSPATT00008654001 Chromosome undetermined scaffold_22,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None
 
H3HCL1_PHYRM
EnsemblProtists»
0.0
Kinesin motor domain-containing protein Phytophthora ramorum
TI:164328 None
 
Q8ILH0_PLAF7
EnsemblProtists»
0.0
PF3D7_1429400 rRNA (Adenosine-2'-O-)-methyltransferase,
putative (EC 2.1.1.-)		 Plasmodium falciparum
TI:5833 None
 
A0A2K2BXY5_POPTR
EnsemblPlants»
0.0
POPTR_001G150900 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Populus trichocarpa
TI:3694 None
 
A0A2A6BVM2_PRIPA
EnsemblMetazoa»
0.0
WBGene00103226 SpoU_methylase domain-containing protein Pristionchus pacificus
TI:54126 None
 
A0A251P7M0_PRUPE
EnsemblPlants»
0.0
PRUPE_5G055400 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Prunus persica
TI:3760 None
 
A0A0G2JYA7_RAT
RGD»
1.0
Tarbp1 TAR (HIV-1) RNA binding protein 1 Rattus norvegicus
TI:10116 None
   
B9SEE0_RICCO
EnsemblBacteria»
0.0
RCOM_0702910 RNA binding protein, putative Ricinus communis
TI:3988 None
 
TRM3_YEAST
SGD»
4.2
TRM3 tRNA (guanosine(18)-2'-O)-methyltransferase (EC 2.1.1.34) (tRNA
[Gm18] ribose methylase) (tRNA methyltransferase 3)		 Saccharomyces cerevisiae
TI:4932 None
 
D8QRC1_SELML
EnsemblPlants»
0.0
SELMODRAFT_77385 SELMODRAFT_95047 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Selaginella moellendorffii
TI:88036 None
 
K4A4R6_SETIT
EnsemblPlants»
0.0
tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Setaria italica
TI:4555 None
 
A0A3Q7HRV7_SOLLC
EnsemblPlants»
0.0
101255721 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Solanum lycopersicum
TI:4081 None
   
C5WNP1_SORBI
EnsemblPlants»
0.0
SORBI_3001G544300 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Sorghum bicolor
TI:4558 None
 
A0A7M7PNS6_STRPU
EnsemblMetazoa»
0.0
tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Strongylocentrotus purpuratus
TI:7668 None
   
F1RGW6_PIG
Ensembl»
0.0
TARBP1 TAR (HIV-1) RNA binding protein 1 Sus scrofa
TI:9823 None
   
B8C392_THAPS
EnsemblProtists»
0.0
THAPSDRAFT_22808 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Thalassiosira pseudonana
TI:35128 None
 
A0A061G4V4_THECC
EnsemblPlants»
0.0
TCM_015848 tRNA/rRNA methyltransferase family
protein isoform 1		 Theobroma cacao
TI:3641 None
 
D6WA65_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_00457 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Tribolium castaneum
TI:7070 None
 
B3SDD6_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_5097 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Trichoplax adhaerens
TI:10228 None
 
A0A3B6IY29_WHEAT
EnsemblPlants»
0.0
CFC21_059760 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Triticum aestivum
TI:4565 None
 
A0A3B6KV23_WHEAT
EnsemblPlants»
0.0
CFC21_069279 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Triticum aestivum
TI:4565 None
 
A0A3B6U6I2_WHEAT
EnsemblPlants»
0.0
CFC21_112474 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Triticum aestivum
TI:4565 None
 
Q381K3_TRYB2
VEuPathDB»
0.0
Tb11.01.7490 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Trypanosoma brucei
TI:5691 None
 
F6I788_VITVI
EnsemblPlants»
0.0
VIT_00s0204g00080 Uncharacterized protein Vitis vinifera
TI:29760 None 		 
 
F6I789_VITVI
EnsemblPlants»
0.0
VIT_00s0204g00110 tRNA/rRNA methyltransferase SpoU
type domain-containing protein		 Vitis vinifera
TI:29760 None
 
A0A8J0SEX9_XENTR
Xenbase»
0.0
tarbp1 Probable methyltransferase TARBP1 isoform X1 Xenopus tropicalis
TI:8364 None
   
A0A8J1KN50_XENLA
Xenbase»
0.0
tarbp1.L Probable methyltransferase TARBP1 isoform X1 Xenopus laevis
TI:8355 None
   
Q6C9I3_YARLI
EnsemblFungi»
0.0
YALI0_D10989g YALI0D10989p Yarrowia lipolytica
TI:4952 None
 
A0A1D6JJF9_MAIZE
EnsemblPlants»
0.0
ZEAMMB73_Zm00001d027259 tRNA/rRNA methyltransferase
(SpoU) family protein		 Zea mays
TI:4577 None
 
A0A0K9P6Y2_ZOSMR
EnsemblPlants»
0.0
ZOSMA_38G00640 tRNA/rRNA methyltransferase
(SpoU) family protein		 Zostera marina
TI:29655 None