Collated Gene Ontology terms

Biological process:

Molecular function: nuclear DNA replication2013, 2017, 2025 replication fork processing2022, 2025 mitotic G2 DNA damage checkpoint signaling2017, 2025 mitotic DNA replication checkpoint signaling2022, 2025 DNA replication2017, 2025 DNA damage checkpoint signaling2017, 2025 cell division2025 eggshell chorion gene amplification2013 DNA replication initiation2025 CMG complex assembly2025

Cellular component: nucleus2006, 2017, 2018, 2025 replisome2017, 2025 replication fork2017, 2025

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 37/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
DONS_MOUSE
Ensembl»
7.1
Donson Protein downstream neighbor of Son (Protein 3SG) Mus musculus
TI:10090 None
 
E9PSU2_RAT
RGD»
2.5
Donson DNA replication fork stabilization factor DONSON Rattus norvegicus
TI:10116 None
   
DONS_XENLA
Xenbase»
0.0
donson Protein downstream neighbor of son homolog Xenopus laevis
TI:8355 None
 
DONS_XENTR
Xenbase»
0.0
donson Protein downstream neighbor of son homolog Xenopus tropicalis
TI:8364 None
 
DONS_HUMAN
Ensembl»
4.5
DONSON Protein downstream neighbor of Son (B17) Homo sapiens
TI:9606 None
 
A0A287BJG1_PIG
Ensembl»
0.0
DONSON DNA replication fork stabilization factor
DONSON (Protein downstream neighbor of Son)		 Sus scrofa
TI:9823 None
 
A0A8I3PLX5_CANLF
Ensembl»
0.0
DONSON DNA replication fork stabilization factor DONSON Canis lupus
TI:9612 None
   
A0A8V0YL29_CHICK
Ensembl»
0.5
DONSON DNA replication fork stabilization factor DONSON Gallus gallus
TI:9031 None
   
A0A9L0RLX8_HORSE
Ensembl»
0.0
DONSON DNA replication fork stabilization factor DONSON Equus caballus
TI:9796 None
   
F6RSI9_BOVIN
Ensembl»
0.0
DONSON DNA replication fork stabilization factor DONSON Bos taurus
TI:9913 None
   
F6SG92_MACMU
Ensembl»
0.0
DONSON DNA replication fork stabilization factor DONSON Macaca mulatta
TI:9544 None
   
F6VIV5_MONDO
Ensembl»
0.0
DONSON DNA replication fork stabilization factor DONSON Monodelphis domestica
TI:13616 None
   
F7AHK1_ORNAN
Ensembl»
0.0
DONSON DNA replication fork stabilization factor DONSON Ornithorhynchus anatinus
TI:9258 None
   
G3R9E4_GORGO
Ensembl»
0.0
DONSON DNA replication fork stabilization factor DONSON Gorilla gorilla
TI:9593 None
 
G1KD20_ANOCA
Ensembl»
0.0
DONSON DNA replication fork stabilization factor DONSON Anolis carolinensis
TI:28377 None
   
DONS_DROME
FlyBase»
2.1
hd Protein downstream neighbor of
son homolog (Protein humpty dumpty)		 Drosophila melanogaster
TI:7227 None
 
A0A1I9LR33_ARATH
TAIR»
0.5
At3g54750 Downstream neighbor of Son Arabidopsis thaliana
TI:3702 None
 
A0A1U8IQB8_GOSHI
neXtProt»
0.0
LOC107899196 Protein downstream neighbor of Son isoform X1 Gossypium hirsutum
TI:3635 None
   
A0A1U8LBB3_GOSHI
euHCVdb»
0.0
LOC107925687 Protein downstream neighbor of Son Gossypium hirsutum
TI:3635 None
   
A0A8J1M5P0_XENLA
CTD»
0.0
donson.L Protein downstream neighbor of
son homolog isoform X1		 Xenopus laevis
TI:8355 None
   
A0A9R0J200_SPIOL
euHCVdb»
0.0
LOC110798195 Uncharacterized protein isoform X1 Spinacia oleracea
TI:3562 None
   
A0A9R0JR35_SPIOL
euHCVdb»
0.0
LOC110783932 Protein downstream neighbor of Son Spinacia oleracea
TI:3562 None
   
A0A061EVY2_THECC
euHCVdb»
0.0
TCM_023151 Downstream neighbor of son, putative isoform 1 Theobroma cacao
TI:3641 None
 
A0A067G5Q5_CITSI
euHCVdb»
0.0
CISIN_1g006670mg Protein downstream neighbor of Son Citrus sinensis
TI:2711 None
 
A0A072TXB3_MEDTR
EnsemblPlants»
0.0
25497873 Uncharacterized protein Medicago truncatula
TI:3880 None
 
A0A072U4M0_MEDTR
EnsemblPlants»
0.0
25499530 Downstream neighbor of
Son-like protein, putative		 Medicago truncatula
TI:3880 None
 
A0A0A0LBQ2_CUCSA
neXtProt»
0.0
Csa_3G791490 Protein downstream neighbor of Son Cucumis sativus
TI:3659 None
 
A0A0K9NV03_ZOSMR
euHCVdb»
0.0
ZOSMA_59G00230 Donson Zostera marina
TI:29655 None
 
A0A0Q3GIS2_BRADI
EnsemblPlants»
0.0
LOC100824058 Protein downstream neighbor of Son Brachypodium distachyon
TI:15368 None
 
A0A0Q3GXY6_BRADI
EnsemblPlants»
0.0
LOC100822370 Protein downstream neighbor of Son Brachypodium distachyon
TI:15368 None
 
A0A1B6PEA8_SORBI
neXtProt»
0.0
SORBI_3008G176800 Protein downstream neighbor of Son Sorghum bicolor
TI:4558 None
 
A0A1D6KGK8_MAIZE
EnsemblPlants»
0.0
LOC100274059 Protein downstream neighbor of Son Zea mays
TI:4577 None
 
A0A1U8AKJ3_NELNU
euHCVdb»
0.0
LOC104601466 Protein downstream neighbor of Son Nelumbo nucifera
TI:4432 None
   
A0A1Y1HJZ6_KLENI
euHCVdb»
0.0
KFL_000200220 Uncharacterized protein Klebsormidium nitens
TI:105231 None
 
A0A251SS78_HELAN
neXtProt»
0.0
HannXRQ_Chr13g0398781 HanXRQr2_Chr13g0583261 Putative donson Helianthus annuus
TI:4232 None
 
A0A251VIV8_HELAN
euHCVdb»
0.0
HannXRQ_Chr02g0052851 HanXRQr2_Chr02g0078361 Donson Helianthus annuus
TI:4232 None
 
A0A2A6CZE2_PRIPA
EnsemblMetazoa»
0.0
WBGene00113435 Uncharacterized protein Pristionchus pacificus
TI:54126 None
   
A0A2C9VDB9_MANES
euHCVdb»
0.0
MANES_08G037500v8 Protein downstream neighbor of Son Manihot esculenta
TI:3983 None
 
A0A2G3AHA0_CAPAN
euHCVdb»
0.0
T459_01501 Protein downstream neighbor of Son Capsicum annuum
TI:4072 None
 
A0A2I4H4T1_JUGRE
euHCVdb»
0.0
LOC109013494 Uncharacterized protein LOC109013494 Juglans regia
TI:51240 None
   
A0A2K1ICA2_PHYPA
EnsemblPlants»
0.0
LOC112277696 Protein downstream neighbor of Son Physcomitrium patens
TI:3218 None
 
A0A2K1KQM9_PHYPA
EnsemblPlants»
0.0
PHYPA_006977 Uncharacterized protein Physcomitrium patens
TI:3218 None
 
A0A2K2A515_POPTR
euHCVdb»
0.0
POPTR_006G199200 Protein downstream neighbor of Son Populus trichocarpa
TI:3694 None
 
A0A2K3DYS2_CHLRE
euHCVdb»
0.0
CHLRE_03g197600v5 Uncharacterized protein Chlamydomonas reinhardtii
TI:3055 None
 
A0A2R6XJR2_MARPO
euHCVdb»
0.0
MARPO_0011s0047 Uncharacterized protein Marchantia polymorpha
TI:3197 None
 
A0A3B6EKK0_WHEAT
EnsemblPlants»
0.0
LOC123062253 Protein downstream neighbor of Son Triticum aestivum
TI:4565 None
   
A0A3B6GWP6_WHEAT
EnsemblPlants»
0.0
LOC123079383 Protein downstream neighbor of Son Triticum aestivum
TI:4565 None
   
A0A3Q7E8B7_SOLLC
EnsemblPlants»
0.0
LOC101266252 Protein downstream neighbor of Son Solanum lycopersicum
TI:4081 None
   
A0A7M7PE88_STRPU
EnsemblMetazoa»
0.0
Protein downstream neighbor of son homolog Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7PJ59_STRPU
EnsemblMetazoa»
0.0
Protein downstream neighbor of Son Strongylocentrotus purpuratus
TI:7668 None
   
A0A9J7N302_BRAFL
euHCVdb»
0.0
LOC118423487 Protein downstream neighbor of son homolog Branchiostoma floridae
TI:7739 None
   
A0A9R1WFT0_LACSA
neXtProt»
0.0
LSAT_V11C200095400 Donson Lactuca sativa
TI:4236 None
 
A0A9R1XBC3_LACSA
neXtProt»
0.0
LSAT_V11C600311700 Donson Lactuca sativa
TI:4236 None
 
A7RRL7_NEMVE
neXtProt»
0.0
NEMVEDRAFT_v1g91106 Protein downstream neighbor of son homolog Nematostella vectensis
TI:45351 None
 
A8X3T0_CAEBR
WormBase»
0.0
dnsn-1 Protein CBG07061 Caenorhabditis briggsae
TI:6238 None
 
B3RX07_TRIAD
CTD»
0.0
TRIADDRAFT_56951 Protein downstream neighbor of Son Trichoplax adhaerens
TI:10228 None
 
B7QHW0_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW014184 Protein downstream neighbor of Son, putative Ixodes scapularis
TI:6945 None
 
B9IIG7_POPTR
euHCVdb»
0.0
POPTR_016G065600 Donson Populus trichocarpa
TI:3694 None
 
B9SDN4_RICCO
neXtProt»
0.0
RCOM_0422700 Protein downstream neighbor of Son Ricinus communis
TI:3988 None
 
D6WA58_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_01105 Protein downstream neighbor
of son homolog-like Protein		 Tribolium castaneum
TI:7070 None
 
D7SNM3_VITVI
euHCVdb»
0.0
VIT_05s0029g00830 Protein downstream neighbor of Son Vitis vinifera
TI:29760 None
 
D7TUE6_VITVI
neXtProt»
0.0
VIT_03s0017g01970 Protein downstream neighbor of Son Vitis vinifera
TI:29760 None
 
D8R2U7_SELML
euHCVdb»
0.0
SELMODRAFT_439222 SOUL heme-binding protein Selaginella moellendorffii
TI:88036 None
 
D8RYN2_SELML
euHCVdb»
0.0
SELMODRAFT_442995 SOUL heme-binding protein Selaginella moellendorffii
TI:88036 None
 
E9GIR3_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_24132 EOG090X09DI Daphnia pulex
TI:6669 None
 
F2EA40_HORVV
EnsemblPlants»
0.0
LOC123444570 Predicted protein Hordeum vulgare
TI:4513 None
 
F4P336_BATDJ
euHCVdb»
0.0
BATDEDRAFT_88922 Uncharacterized protein Batrachochytrium dendrobatidis
TI:109871 None
 
G2HF01_PANTR
Ensembl»
0.0
DONSON DNA replication fork stabilization factor
DONSON (Downstream neighbor of SON)		 Pan troglodytes
TI:9598 None
 
H2N2F8_ORYLA
Ensembl»
0.0
donson Downstream neighbor of SON Oryzias latipes
TI:8090 None
   
H2XXS5_CIOIN
Ensembl»
0.0
Uncharacterized protein Ciona intestinalis
TI:7719 None
 
H3HCJ7_PHYRM
EnsemblProtists»
0.0
Uncharacterized protein Phytophthora ramorum
TI:164328 None
 
I1JQC5_SOYBN
EnsemblPlants»
0.0
LOC100816076 Donson Glycine max
TI:3847 None
 
I1NAX1_SOYBN
EnsemblPlants»
0.0
LOC100796531 Protein downstream neighbor of Son Glycine max
TI:3847 None
 
K3Z4K2_SETIT
EnsemblPlants»
0.0
LOC101759172 Protein downstream neighbor of Son Setaria italica
TI:4555 None
 
M1BX71_SOLTU
EnsemblPlants»
0.0
LOC102591670 Protein downstream neighbor of Son Solanum tuberosum
TI:4113 None
   
M4CSA2_BRACM
EnsemblPlants»
0.0
Protein downstream neighbor of Son-like Brassica campestris
TI:3711 None
   
M4DE72_BRACM
EnsemblPlants»
0.0
Protein downstream neighbor of Son Brassica campestris
TI:3711 None
   
M5W6C7_PRUPE
euHCVdb»
0.0
PRUPE_7G089700 Protein downstream neighbor of Son Prunus persica
TI:3760 None
 
Q2QM08_ORYSJ
euHCVdb»
0.0
LOC_Os12g42700 Os12g0621700 Expressed protein (Os12g0621700 protein)
(cDNA clone:J033044P17, full insert sequence)		 Oryza sativa
TI:4530 None
 
Q54MP7_DICDI
dictyBase»
0.5
DDB_G0285805 Uncharacterized protein Dictyostelium discoideum
TI:44689 None
 
Q7Q6F4_ANOGA
EnsemblMetazoa»
0.0
1276541 AGAP005874-PA Anopheles gambiae
TI:7165 None
 
Q95X82_CAEEL
WormBase»
0.5
dnsn-1 Downstream Neighbor of SoN homolog Caenorhabditis elegans
TI:6239 None
 
T1FUV1_HELRO
EnsemblMetazoa»
0.0
20212597 Uncharacterized protein Helobdella robusta
TI:6412 None
 
W1PI10_AMBTC
euHCVdb»
0.0
AMTR_s00019p00232970 Protein downstream neighbor of Son Amborella trichopoda
TI:13333 None
 
W5MYP3_LEPOC
Ensembl»
0.0
DNA replication fork stabilization factor DONSON Lepisosteus oculatus
TI:7918 None
 
A0A3B6LDX2_WHEAT
EnsemblPlants»
0.0
LOC123115502 Downstream neighbor of Son Triticum aestivum
TI:4565 None
   
A0A3B6MKB2_WHEAT
EnsemblPlants»
0.0
Protein downstream neighbor of Son Triticum aestivum
TI:4565 None
   
A0A8I6Y5X4_HORVV
EnsemblPlants»
0.0
LOC123395396 Uncharacterized protein Hordeum vulgare
TI:4513 None
   
A0ABM3AD86_GOSHI
euHCVdb»
0.0
LOC121219191 Uncharacterized protein Gossypium hirsutum
TI:3635 None
   
A0ABM3AG93_GOSHI
euHCVdb»
0.0
LOC121219566 Protein downstream neighbor of son homolog Gossypium hirsutum
TI:3635 None
   
A0ABM3BTJ8_GOSHI
euHCVdb»
0.0
LOC121229663 Protein downstream neighbor of Son Gossypium hirsutum
TI:3635 None
   
A0A022PV84_ERYGU
euHCVdb»
0.0
MIMGU_mgv1a009207mg Protein downstream neighbor of Son Erythranthe guttata
TI:4155 None
 
A0A0R0HWW1_SOYBN
EnsemblPlants»
0.0
LOC100782210 Uncharacterized protein Glycine max
TI:3847 None
 
A0A0R0KNG9_SOYBN
EnsemblPlants»
0.0
GLYMA_03G078500 Uncharacterized protein Glycine max
TI:3847 None
 
A0A804IYA6_MUSAM
EnsemblPlants»
0.0
GSMUA_143870.1 (wild Malaysian banana) hypothetical protein Musa acuminata
TI:4641 None
 
A0A804IYA7_MUSAM
EnsemblPlants»
0.0
Uncharacterized protein Musa acuminata
TI:4641 None
   
A0A9K3HAJ8_HELAN
euHCVdb»
0.0
HanXRQr2_Chr13g0571661 Uncharacterized protein Helianthus annuus
TI:4232 None
 
A0A9K3I4G8_HELAN
euHCVdb»
0.0
HanXRQr2_Chr09g0377391 Uncharacterized protein Helianthus annuus
TI:4232 None
 
A0A9R1FNA3_WHEAT
EnsemblPlants»
0.0
LOC123071009 Protein downstream neighbor of Son Triticum aestivum
TI:4565 None
 
A0ABI7YWG1_FELCA
Ensembl»
0.0
DONSON DNA replication fork stabilization factor DONSON Felis catus
TI:9685 None
   
D7SNM6_VITVI
euHCVdb»
0.0
VIT_05s0029g00810 Uncharacterized protein Vitis vinifera
TI:29760 None
 
F0ZY43_DICPU
TubercuList»
0.0
DICPUDRAFT_92846 Uncharacterized protein Dictyostelium purpureum
TI:5786 None
 
F6GWC8_VITVI
euHCVdb»
0.0
VIT_05s0029g00860 Uncharacterized protein Vitis vinifera
TI:29760 None
 
K7LR09_SOYBN
EnsemblPlants»
0.0
GLYMA_11G163700 Uncharacterized protein Glycine max
TI:3847 None
 
W1P4J2_AMBTC
euHCVdb»
0.0
AMTR_s00083p00039080 Uncharacterized protein Amborella trichopoda
TI:13333 None