Collated Gene Ontology terms

Biological process: glutamate-tRNA ligase activity(2009, 2011, 2013, 2016, 2023, 2025) ATP binding(2004, 2008, 2025) nucleotide binding(2025) ligase activity(2025) aminoacyl-tRNA ligase activity(2025) zinc ion binding(2009, 2014, 2021, 2022, 2025) tRNA binding(2025) glutamate-tRNA(Gln) ligase activity(2011, 2025) metal ion binding(2025) RNA binding(2025)
glutamine-tRNA ligase activity2013, 2024 metallopeptidase activity2025

Molecular function: glutamyl-tRNA aminoacylation2005, 2009, 2011, 2013, 2016, 2023, 2025 tRNA aminoacylation2025 translation2025 tRNA aminoacylation for protein translation2025 reproductive structure development2025 post-embryonic development2025 tRNA aminoacylation for mitochondrial protein translation2011, 2025 tRNA modification2025 mitochondrial translation2004, 2013, 2025 glutaminyl-tRNA aminoacylation2024
tRNA wobble base modification2021 plant ovule development2005 mitochondrion organization2005 mitochondrial glutamyl-tRNA aminoacylation2013 chloroplast organization2005

Cellular component: mitochondrion2005, 2009, 2011, 2013, 2016, 2018, 2022, 2024, 2025 cytosol2014, 2017, 2021, 2025 cytoplasm2018, 2025 chloroplast2005, 2021, 2025 mitochondrial matrix2018, 2025 plastid2019 plasma membrane2010 chloroplast stroma2021 apicoplast2013

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 0/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 1/4 
Harosa: 3/4 
Hacrobia: 0/0 
Plants: 37/39 
Archea: 0/8 
Bacteria: 35/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
A0A8V0YTD4_CHICK
Ensembl»
1.0
EARS2 Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial (EC 6.1.1.17) (EC 6.1.1.24)
(Glutamate--tRNA(Gln) ligase EARS2, mitochondrial) (Glutamyl-tRNA synthetase) (Mitochondrial glutamyl-tRNA synthetase)		 Gallus gallus
TI:9031 None
   
SYEM_CHICK
CTD»
1.0
EARS2 Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial (EC 6.1.1.24) (Glutamate--tRNA(Gln) ligase EARS2,
mitochondrial) (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS) (Mitochondrial glutamyl-tRNA synthetase) (mtGluRS)		 Gallus gallus
TI:9031 None
 
SYEM_HUMAN
Ensembl»
4.2
EARS2 Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial (EC 6.1.1.24) (Glutamate--tRNA(Gln) ligase EARS2,
mitochondrial) (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS) (Mitochondrial glutamyl-tRNA synthetase) (mtGluRS)		 Homo sapiens
TI:9606 None
 
A0A8I6A644_RAT
RGD»
1.0
ENSRNOG00000067512 Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial (EC 6.1.1.17) (EC 6.1.1.24)
(Glutamate--tRNA(Gln) ligase EARS2, mitochondrial) (Glutamyl-tRNA synthetase) (Mitochondrial glutamyl-tRNA synthetase)		 Rattus norvegicus
TI:10116 None
   
SYEM_MOUSE
Ensembl»
3.0
Ears2 Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial (EC 6.1.1.24) (Glutamate--tRNA(Gln) ligase EARS2,
mitochondrial) (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS) (Mitochondrial glutamyl-tRNA synthetase) (mtGluRS)		 Mus musculus
TI:10090 None
 
Q9VV59_DROME
FlyBase»
2.8
GluRS-m Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial (EC 6.1.1.17) (EC 6.1.1.24)
(Glutamate--tRNA(Gln) ligase EARS2, mitochondrial) (Glutamyl-tRNA synthetase) (Mitochondrial glutamyl-tRNA synthetase)		 Drosophila melanogaster
TI:7227 None
 
SYEM_YEAST
SGD»
4.4
MSE1 Glutamate--tRNA ligase, mitochondrial (EC
6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS)		 Saccharomyces cerevisiae
TI:4932 None
 
SYEM_ARATH
TAIR»
4.1
OVA3 Glutamate--tRNA ligase, chloroplastic/mitochondrial (EC 6.1.1.17) (AtERS)
(Glutamyl-tRNA synthetase) (GluRS) (Protein OVULE ABORTION 3)		 Arabidopsis thaliana
TI:3702 None
 
O44413_CAEEL
WormBase»
1.0
ears-2 Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial (EC 6.1.1.17) (EC 6.1.1.24)
(Glutamate--tRNA(Gln) ligase EARS2, mitochondrial) (Glutamyl-tRNA synthetase) (Mitochondrial glutamyl-tRNA synthetase)		 Caenorhabditis elegans
TI:6239 None
 
SYEM_DANRE
ZFIN»
1.0
ears2 Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial (EC 6.1.1.24) (Glutamate--tRNA(Gln) ligase EARS2,
mitochondrial) (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS) (Mitochondrial glutamyl-tRNA synthetase) (mtGluRS)		 Danio rerio
TI:7955 None
 
SYE_ECOLI
EnsemblBacteria»
3.4
gltX Glutamate--tRNA ligase (EC
6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS)		 Escherichia coli
TI:562 None
 
GLUQ_ECOLI
EnsemblBacteria»
3.9
gluQ Glutamyl-Q tRNA(Asp) synthetase
(Glu-Q-RSs) (EC 6.1.1.-)		 Escherichia coli
TI:562 None
 
Q869Z3_DICDI
dictyBase»
1.0
mgluS glutamate--tRNA ligase (EC
6.1.1.17) (Glutamyl-tRNA synthetase)		 Dictyostelium discoideum
TI:44689 None
 
SYEM_SCHPO
PomBase»
2.0
mse1 Glutamate--tRNA ligase, mitochondrial (EC
6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS)		 Schizosaccharomyces pombe
TI:4896 None