Collated Gene Ontology terms

Biological process: translation initiation factor activity(2006, 2007, 2013, 2021, 2024) RNA binding(2014, 2024) double-stranded RNA binding(2013, 2014, 2024) tRNA binding(2024) RNA strand annealing activity(2007, 2024) ribosomal small subunit binding(2019, 2024) translation initiation factor binding(2019, 2024) protein kinase binding(2017, 2024) mRNA binding(2020) translation factor activity, RNA binding(2003)
ribosomal large subunit binding2016

Molecular function: translational initiation2003, 2006, 2007, 2022, 2023, 2024 translation2006, 2024 ribosome assembly2023, 2024 formation of translation preinitiation complex2013, 2019, 2024 formation of cytoplasmic translation initiation complex2013, 2019, 2024 translation reinitiation2019, 2024 formation of translation initiation ternary complex2019, 2024 regulation of miRNA processing2017, 2024 regulation of hemoglobin biosynthetic process2017, 2024 erythrocyte maturation2017, 2024
cytoplasmic translational initiation2005

Cellular component: cytoplasm2017, 2023, 2024 eukaryotic 43S preinitiation complex2006, 2007, 2013, 2022, 2024 eukaryotic 48S preinitiation complex2013, 2023, 2024 synapse2024 multi-eIF complex2023, 2024 cytosol2006, 2009, 2011, 2013, 2015 plastid2019 nucleoplasm2015 mitochondrion2019 membrane2024
cytoplasmic stress granule2020 chloroplast2024

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 4/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 38/39 
Archea: 8/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
IF1A_YEAST
SGD»
10.6
TIF11 Eukaryotic translation initiation factor 1A (eIF-1A)
(Eukaryotic translation initiation factor 4C) (eIF-4C)		 Saccharomyces cerevisiae
TI:4932 None
 
IF1AX_HUMAN
Ensembl»
4.9
EIF1AX Eukaryotic translation initiation factor 1A, X-chromosomal (eIF-1A X isoform)
(eIF1A X isoform) (Eukaryotic translation initiation factor 4C) (eIF-4C)		 Homo sapiens
TI:9606 None
 
Q9VEA1_DROME
FlyBase»
2.5
eIF1A Eukaryotic translation initiation factor 4C Drosophila melanogaster
TI:7227 None
 
A0A8I6A8I7_RAT
RGD»
2.0
Eif1ax Eukaryotic translation initiation factor 4C Rattus norvegicus
TI:10116 None
   
IF1A_SCHPO
PomBase»
3.1
tif11 Eukaryotic translation initiation factor 1A (eIF-1A)
(Eukaryotic translation initiation factor 4C) (eIF-4C)		 Schizosaccharomyces pombe
TI:4896 None
 
Q4V9N9_DANRE
ZFIN»
3.4
wu:fb26b09 Eukaryotic translation initiation factor 4C Danio rerio
TI:7955 None
 
IF1A_RAT
RGD»
1.8
Eif1a Eukaryotic translation initiation factor 1A (eIF-1A) (Eukaryotic translation
initiation factor 4C) (eIF-4C) (Liver regeneration-related protein LRRG048)		 Rattus norvegicus
TI:10116 None
 
IF1AY_HUMAN
Ensembl»
1.0
EIF1AY Eukaryotic translation initiation factor 1A, Y-chromosomal (eIF-1A Y isoform)
(eIF1A Y isoform) (Eukaryotic translation initiation factor 4C) (eIF-4C)		 Homo sapiens
TI:9606 None
 
IF1AX_MOUSE
Ensembl»
0.0
Eif1ax Eukaryotic translation initiation factor 1A, X-chromosomal (eIF-1A X isoform)
(eIF1A X isoform) (Eukaryotic translation initiation factor 4C) (eIF-4C)		 Mus musculus
TI:10090 None
 
F4K1D3_ARATH
TAIR»
0.8
MXH1.2 Eukaryotic translation initiation factor 4C Arabidopsis thaliana
TI:3702 None
 
IF1A_DICDI
dictyBase»
1.0
eif1a Eukaryotic translation initiation factor 1A (eIF-1A)
(Eukaryotic translation initiation factor 4C) (eIF-4C)		 Dictyostelium discoideum
TI:44689 None
 
Q5XJR0_DANRE
ZFIN»
1.0
eif1ax Eukaryotic translation initiation factor 4C Danio rerio
TI:7955 None
 
Q9TXU7_CAEEL
WormBase»
1.0
eif-1.a Eukaryotic translation initiation factor 4C Caenorhabditis elegans
TI:6239 None
 
IF1A_MOUSE
Ensembl»
0.0
Eif1a Eukaryotic translation initiation factor 1A (eIF-1A)
(Eukaryotic translation initiation factor 4C) (eIF-4C)		 Mus musculus
TI:10090 None
 
Q9SJB9_ARATH
TAIR»
0.8
At2g04520 Eukaryotic translation initiation factor 4C Arabidopsis thaliana
TI:3702 None
 
A0A1Y7VJE9_MOUSE
Ensembl»
0.0
Eif1ad13 Eukaryotic translation initiation factor 4C Mus musculus
TI:10090 None
   
A0A1Y7VK80_MOUSE
Ensembl»
0.0
Eif1ad12 Eukaryotic translation initiation factor 4C Mus musculus
TI:10090 None
   
A0A1Y7VLT7_MOUSE
Ensembl»
0.0
Eif1ad4 Eukaryotic translation initiation factor 4C Mus musculus
TI:10090 None
   
A0A1Y7VNG9_MOUSE
Ensembl»
0.0
Eif1ad18 Eukaryotic translation initiation factor
1A domain containing 18		 Mus musculus
TI:10090 None
   
A0A8V0XB11_CHICK
Ensembl»
0.0
EIF1AX Eukaryotic translation initiation factor 4C Gallus gallus
TI:9031 None
   
F6YNI8_MOUSE
Ensembl»
0.0
Eif1ad19 Eukaryotic translation initiation factor 4C Mus musculus
TI:10090 None
   
J3QMW5_MOUSE
Ensembl»
0.0
Eif1ad17 Eukaryotic translation initiation factor 4C Mus musculus
TI:10090 None
   
J3QNT6_MOUSE
Ensembl»
0.0
Eif1ad15 Eukaryotic translation initiation factor 4C Mus musculus
TI:10090 None
   
J3QP87_MOUSE
Ensembl»
0.0
Eif1ad14 Eukaryotic translation initiation factor
1A domain containing 14		 Mus musculus
TI:10090 None
   
J3QPI8_MOUSE
Ensembl»
0.0
Eif1ad16 Eukaryotic translation initiation factor 4C Mus musculus
TI:10090 None
   
J3QQ02_MOUSE
Ensembl»
0.0
Eif1ad11 Eukaryotic translation initiation factor 4C Mus musculus
TI:10090 None
   
Q3TQZ4_MOUSE
Ensembl»
0.0
Eif1ad3 Eukaryotic translation initiation factor 4C Mus musculus
TI:10090 None
 
Q3UT53_MOUSE
Ensembl»
0.0
Eif1ad2 Eukaryotic translation initiation factor 4C Mus musculus
TI:10090 None
 
Q3UTA4_MOUSE
Ensembl»
0.0
Eif1ad10 Eukaryotic translation initiation factor 4C Mus musculus
TI:10090 None
 
Q8BX20_MOUSE
Ensembl»
0.0
Eif1ad7 Eukaryotic translation initiation factor 4C Mus musculus
TI:10090 None