Collated Gene Ontology terms

Biological process: ubiquitin binding(2017) transferase activity(2025) oxidoreductase activity(2025) metal ion binding(2025) iron-sulfur cluster chaperone activity(2025) histone binding(2025) acyltransferase activity(2025) GTPase activity(2025) GTP binding(2025) DNA-binding transcription factor activity(2001)

Molecular function: iron-sulfur cluster assembly2013, 2018, 2024, 2025 protein maturation2024, 2025 chromosome segregation2025 tRNA wobble uridine modification2013, 2025 ubiquitin recycling2017 proteasome-mediated ubiquitin-dependent protein catabolic process2017 regulation of transcription by RNA polymerase II2001, 2003 ribosome biogenesis2025 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum2023 regulation of DNA-templated transcription2025
rRNA processing2025 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2018 mRNA export from nucleus2017 intracellular protein transport2017 intra-Golgi vesicle-mediated transport2017 endoplasmic reticulum to Golgi vesicle-mediated transport2017 [4Fe-4S] cluster assembly2025

Cellular component: cytosolic [4Fe-4S] assembly targeting complex2012, 2018, 2019, 2024, 2025 cytoplasm2018, 2024, 2025 MMXD complex2010, 2025 nucleus2013, 2018, 2025 cytosol2012, 2013, 2019, 2025 catalytic step 2 spliceosome2021 Cdc73/Paf1 complex2021 t-UTP complex2018 small-subunit processome2024 ribonucleoprotein complex2025
nucleolus2025 THO complex part of transcription export complex2017 Set1C/COMPASS complex2023 COPI vesicle coat2022

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 13/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 3/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 38/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
F4JVW1_ARATH
TAIR»
0.5
At4g32990 Probable cytosolic iron-sulfur protein
assembly protein CIAO1 homolog		 Arabidopsis thaliana
TI:3702 None
 
CIA1_ARATH
TAIR»
1.3
CIA1 Protein CIA1 (Cytosolic iron-sulfur protein
assembly 1) (Protein EMBRYO DEFECTIVE 1345)		 Arabidopsis thaliana
TI:3702 None
 
CIAO1_YEAST
SGD»
3.5
CIA1 Cytosolic iron-sulfur protein assembly protein 1 Saccharomyces cerevisiae
TI:4932 None
 
A0A8V0ZD81_CHICK
Ensembl»
0.5
CIAO1 Probable cytosolic iron-sulfur protein assembly
protein CIAO1 (WD repeat-containing protein 39)		 Gallus gallus
TI:9031 None
   
CIAO1_HUMAN
Ensembl»
4.4
CIAO1 Probable cytosolic iron-sulfur protein assembly
protein CIAO1 (WD repeat-containing protein 39)		 Homo sapiens
TI:9606 None
 
CIAO1_DROME
FlyBase»
2.2
Ciao1 Probable cytosolic iron-sulfur
protein assembly protein Ciao1		 Drosophila melanogaster
TI:7227 None
 
CIAO1_MOUSE
Ensembl»
3.8
Ciao1 Probable cytosolic iron-sulfur protein assembly
protein CIAO1 (WD repeat-containing protein 39)		 Mus musculus
TI:10090 None
 
CIAO1_RAT
RGD»
2.0
Ciao1 Probable cytosolic iron-sulfur protein assembly
protein CIAO1 (WD repeat-containing protein 39)		 Rattus norvegicus
TI:10116 None
 
CIAO1_CAEEL
WormBase»
1.0
ciao-1 Probable cytosolic iron-sulfur protein
assembly protein CIAO1 homolog		 Caenorhabditis elegans
TI:6239 None
 
CIAO1_DANRE
ZFIN»
1.8
ciao1 Probable cytosolic iron-sulfur protein assembly
protein ciao1 (WD repeat-containing protein 39)		 Danio rerio
TI:7955 None
 
CIAO1_DICDI
dictyBase»
1.0
ciao1 Probable cytosolic iron-sulfur protein
assembly protein CIAO1 homolog		 Dictyostelium discoideum
TI:44689 None