Collated Gene Ontology terms

Biological process: RNA binding(2007, 2008, 2009, 2013, 2014, 2016, 2017, 2024) mRNA binding(2003, 2006, 2016, 2018, 2020, 2021, 2022, 2023, 2024) RNA cap binding(2014, 2024) mRNA 3'-UTR binding(2014, 2020, 2021, 2024) nucleic acid binding(2024) S-adenosylmethionine-dependent methyltransferase activity(2024) mRNA 5'-UTR binding(2014, 2016, 2017, 2019, 2022, 2024) sequence-specific mRNA binding(2016, 2017, 2024) U6 snRNA binding(2020, 2021, 2024) tRNA binding(2003, 2013, 2016, 2020, 2024)
7SK snRNA binding2020, 2024 DNA binding2024 translation initiation factor binding2014, 2024 translation activator activity2014, 2024 ribosomal small subunit binding2019, 2024 eukaryotic initiation factor 4E binding2014, 2024 RNA 7-methylguanosine cap binding2019, 2024 poly(U) RNA binding2012, 2016, 2022, 2024 RNA stem-loop binding2017, 2024 myosin binding2017, 2024 poly(A) binding2016, 2024 RNA folding chaperone2023, 2024 translation initiation factor activity2024 proton transmembrane transporter activity2024 poly-pyrimidine tract binding2022 poly(G) binding2012 lysine-acetylated histone binding2024 cadherin binding2018 5S rRNA primary transcript binding2006

Molecular function: RNA processing2009, 2024 positive regulation of translation2013, 2016, 2021, 2024 mRNA stabilization2016, 2019, 2024 tRNA processing2005, 2013, 2016, 2021, 2024 cell differentiation2024 mRNA processing2024 RNA splicing2024 post-transcriptional regulation of gene expression2020, 2024 tRNA 3'-end processing2016, 2021, 2024 regulation of mRNA splicing, via spliceosome2020, 2024
positive regulation of snRNA transcription by RNA polymerase II2020, 2024 positive regulation of protein localization to Cajal body2020, 2024 box C/D RNA 3'-end processing2020, 2024 U6 2'-O-snRNA methylation2020, 2024 translational initiation2014, 2024 negative regulation of translation2016, 2020, 2024 response to amino acid starvation2016, 2024 negative regulation of translational initiation2019, 2024 negative regulation of transcription by RNA polymerase II2013, 2020, 2024 cellular response to rapamycin2016, 2024 cell population proliferation2014, 2024 TORC1 signaling2016, 2024 TOR signaling2014, 2024 tRNA 5'-leader removal2016, 2024 spermatogenesis2020, 2024 positive regulation of viral genome replication2016, 2024 positive regulation of translational initiation2018, 2024 positive regulation of macroautophagy2012, 2024 positive regulation of collagen biosynthetic process2023, 2024 negative regulation of viral transcription2020, 2024 tRNA export from nucleus2016, 2024 protein localization to cytoplasmic stress granule2016, 2024 nuclear histone mRNA catabolic process2016, 2024 IRES-dependent viral translational initiation2016, 2024 regulation of translation2013, 2019, 2024 regulation of cell morphogenesis2011, 2024 cytoskeleton organization2011, 2024 ribosome biogenesis2007, 2019, 2024 positive regulation of 3'-UTR-mediated mRNA stabilization2020, 2024 sno(s)RNA 3'-end processing2024 rRNA processing2019, 2024 embryo development ending in seed dormancy2014, 2024 leaf senescence2012, 2024 translation2024 tRNA folding2017, 2020, 2024 somitogenesis2009, 2024 response to salicylic acid2014, 2024 response to jasmonic acid2014, 2024 response to abscisic acid2014, 2024 positive regulation of G1/S transition of mitotic cell cycle2013 negative regulation of transcription elongation by RNA polymerase II2020 germ cell proliferation2013 cellular heat acclimation2024 tRNA modification2003 syncytial blastoderm mitotic cell cycle2010 spindle assembly involved in male meiosis2009 response to oxygen levels2018 regulation of cardiac muscle cell proliferation2016 regulation of DNA-templated transcription2024 proton transmembrane transport2024 proton motive force-driven ATP synthesis2024 positive regulation of protein targeting to mitochondrion2024 positive regulation of mitochondrial DNA replication2021 positive regulation of cytoplasmic translation2021 oogenesis2024 negative regulation of gene expression2017 negative regulation of cytoplasmic translation2022 negative regulation of cell growth2020 negative regulation of DNA-templated transcription2018 mitochondrion inheritance2009 meiotic cell cycle2024 maturation of 5S rRNA2019 male meiotic nuclear division2010 mRNA catabolic process2014 intracellular copper ion homeostasis2013 histone mRNA metabolic process2003 heat acclimation2014 cytoplasmic translation2005 chromatin remodeling2023 cardiac muscle tissue regeneration2016 abscisic acid-activated signaling pathway2024 ATP biosynthetic process2024

Cellular component: nucleus2006, 2009, 2013, 2014, 2016, 2017, 2018, 2019, 2020, 2022, 2023, 2024 ribonucleoprotein complex2003, 2020, 2024 cytosol2006, 2009, 2013, 2014, 2015, 2016, 2020, 2021, 2023, 2024 cytoplasmic stress granule2013, 2016, 2020, 2022, 2024 nucleoplasm2007, 2013, 2014, 2016, 2023, 2024 cytoplasm2009, 2010, 2012, 2014, 2016, 2018, 2019, 2023, 2024 nucleolus2013, 2014, 2023, 2024 TORC1 complex2014, 2016, 2024 7SK snRNP2020, 2024 cytosolic small ribosomal subunit2016, 2024
P-body2010, 2014, 2024 membrane2014, 2024 mitochondrion2009, 2022, 2024 transcription repressor complex2018 proton-transporting ATP synthase complex, coupling factor F(o)2024 plasma membrane2019 plant-type cell wall2021 phagocytic vesicle2009 fungal biofilm matrix2022 extrinsic component of mitochondrial outer membrane2021 euchromatin2016 chromosome, telomeric region2015 chromatin2021

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 4/4 
Harosa: 3/4 
Hacrobia: 0/0 
Plants: 37/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 5 10 15 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
A1Z9R1_DROME
FlyBase»
1.3
Achl Achilles, isoform A
(Achilles, isoform B) (FI03833p)		 Drosophila melanogaster
TI:7227 None
 
O44760_CAEEL
WormBase»
1.0
larp-5 HTH La-type
RNA-binding domain-containing protein		 Caenorhabditis elegans
TI:6239 None
 
Q54HN9_DICDI
dictyBase»
1.0
DDB_G0289333 HTH La-type
RNA-binding domain-containing protein		 Dictyostelium discoideum
TI:44689 None
 
Q550L4_DICDI
dictyBase»
0.5
DDB_G0277065 HTH La-type
RNA-binding domain-containing protein		 Dictyostelium discoideum
TI:44689 None
 
LA1_ARATH
TAIR»
5.6
LA1 La protein 1 (AtLa1) Arabidopsis thaliana
TI:3702 None
 
LA2_ARATH
TAIR»
1.0
LA2 La protein 2 (AtLa2) Arabidopsis thaliana
TI:3702 None
 
LAH1_SCHPO
PomBase»
6.9
sla1 La protein homolog (La
autoantigen homolog) (La ribonucleoprotein)		 Schizosaccharomyces pombe
TI:4896 None
 
LA_DROME
FlyBase»
3.4
La La protein homolog (La
autoantigen homolog) (La ribonucleoprotein)		 Drosophila melanogaster
TI:7227 None
 
LHP1_YEAST
SGD»
3.7
LHP1 La protein homolog (La
autoantigen homolog) (La ribonucleoprotein)		 Saccharomyces cerevisiae
TI:4932 None
 
A0A8I6GJC3_RAT
RGD»
11.5
Larp1 La ribonucleoprotein 1, translational regulator Rattus norvegicus
TI:10116 None
   
A0A8V0Z015_CHICK
Ensembl»
0.0
LARP1 La ribonucleoprotein 1, translational regulator Gallus gallus
TI:9031 None
   
A0A8I5ZWA7_RAT
RGD»
0.0
Larp1b La ribonucleoprotein 1B Rattus norvegicus
TI:10116 None
   
A0A8V0XQK3_CHICK
Ensembl»
0.0
LARP1B La ribonucleoprotein 1B Gallus gallus
TI:9031 None
   
F6U5V1_MOUSE
Ensembl»
0.0
Larp1b La ribonucleoprotein 1B Mus musculus
TI:10090 None
   
A0A8I5ZLN6_RAT
RGD»
3.0
Larp4 La ribonucleoprotein 4 Rattus norvegicus
TI:10116 None
   
E9QDP4_DANRE
ZFIN»
1.0
LOC100332095 La ribonucleoprotein 4Aa (La-related
protein 4 isoform X1)		 Danio rerio
TI:7955 None
 
A0A8V0XS45_CHICK
Ensembl»
0.0
LARP4B La ribonucleoprotein 4B Gallus gallus
TI:9031 None
   
D3ZF45_RAT
RGD»
2.5
Larp4b La ribonucleoprotein 4B Rattus norvegicus
TI:10116 None
   
A3KP60_DANRE
ZFIN»
0.5
wu:fa55b04 La ribonucleoprotein 6, translational
regulator b (Zgc:162969 protein)		 Danio rerio
TI:7955 None
 
A0A8V0ZVH9_CHICK
Ensembl»
0.0
LARP6 La ribonucleoprotein 6, translational regulator Gallus gallus
TI:9031 None
   
D3ZCR5_RAT
RGD»
3.0
Larp6 La ribonucleoprotein 6, translational regulator Rattus norvegicus
TI:10116 None
   
Q6PHD4_DANRE
ZFIN»
2.1
zgc:66107 La ribonucleoprotein 6, translational regulator
a (La-related protein 6) (Zgc:66107)		 Danio rerio
TI:7955 None
 
A0A8V0ZQM9_CHICK
Ensembl»
0.0
LARP4 La ribonucleoprotein domain family member 4 Gallus gallus
TI:9031 None
   
A0A8V1AKD0_CHICK
Ensembl»
0.0
LARP6L La ribonucleoprotein domain family member 6 Gallus gallus
TI:9031 None
   
LARP1_CAEEL
WormBase»
2.6
larp-1 La-related protein 1 (La
ribonucleoprotein domain family member 1)		 Caenorhabditis elegans
TI:6239 None
 
LARP1_HUMAN
Ensembl»
19.6
LARP1 La-related protein 1 (La
ribonucleoprotein domain family member 1)		 Homo sapiens
TI:9606 None
 
LARP1_MOUSE
Ensembl»
8.5
Larp1 La-related protein 1 (La
ribonucleoprotein domain family member 1)		 Mus musculus
TI:10090 None
 
LARP_DROME
FlyBase»
9.0
larp La-related protein 1 (dLarp) Drosophila melanogaster
TI:7227 None
 
A0A8M9P457_DANRE
CTD»
1.0
larp1 La-related protein 1 isoform X1 Danio rerio
TI:7955 None
   
LRP1A_ARATH
TAIR»
2.1
LARP1A La-related protein 1A (AtLARP1a) Arabidopsis thaliana
TI:3702 None
 
LRP1B_ARATH
TAIR»
2.1
LARP1B La-related protein 1B (AtLARP1b) Arabidopsis thaliana
TI:3702 None
 
LAR1B_HUMAN
Ensembl»
1.5
LARP1B La-related protein 1B (La ribonucleoprotein domain family member 1B)
(La ribonucleoprotein domain family member 2) (La-related protein 2)		 Homo sapiens
TI:9606 None
 
A0A8M2B4Y8_DANRE
CTD»
1.0
larp1b La-related protein 1B isoform X1 Danio rerio
TI:7955 None
   
LRP1C_ARATH
TAIR»
4.5
LARP1C La-related protein 1C (AtLARP1c) Arabidopsis thaliana
TI:3702 None
 
LARP4_HUMAN
Ensembl»
6.3
LARP4 La-related protein 4 (La
ribonucleoprotein domain family member 4)		 Homo sapiens
TI:9606 None
 
LARP4_MOUSE
AG»
1.0
Larp4 La-related protein 4 (La
ribonucleoprotein domain family member 4)		 Mus musculus
TI:10090 None
 
A0A8M6YZR7_DANRE
CTD»
1.0
larp4ab La-related protein 4 isoform X5 Danio rerio
TI:7955 None
   
LAR4B_HUMAN
Ensembl»
3.9
LARP4B La-related protein 4B (La ribonucleoprotein domain family member 4B)
(La ribonucleoprotein domain family member 5) (La-related protein 5)		 Homo sapiens
TI:9606 None
 
LAR4B_MOUSE
Ensembl»
0.5
Larp4b La-related protein 4B (La ribonucleoprotein domain family member 4B)
(La ribonucleoprotein domain family member 5) (La-related protein 5)		 Mus musculus
TI:10090 None
 
A0A8M9PU52_DANRE
ZFIN»
1.0
larp4b La-related protein 4B isoform X1 Danio rerio
TI:7955 None
   
LARP6_HUMAN
Ensembl»
6.1
LARP6 La-related protein 6 (Acheron) (Achn)
(La ribonucleoprotein domain family member 6)		 Homo sapiens
TI:9606 None
 
LARP6_MOUSE
Ensembl»
1.0
Larp6 La-related protein 6 (Acheron) (Achn)
(La ribonucleoprotein domain family member 6)		 Mus musculus
TI:10090 None
 
LRP6A_ARATH
TAIR»
0.0
LARP6A La-related protein 6A (AtLARP6a) Arabidopsis thaliana
TI:3702 None
 
LRP6B_ARATH
TAIR»
1.3
LARP6B La-related protein 6B
(AtLARP6b) (VirF-interacting protein FIP1)		 Arabidopsis thaliana
TI:3702 None
 
LRP6C_ARATH
TAIR»
0.0
LARP6C La-related protein 6C (AtLARP6c) Arabidopsis thaliana
TI:3702 None
 
A0A8V0XBH7_CHICK
Ensembl»
0.0
LARP7 La-related protein 7 (La
ribonucleoprotein domain family member 7)		 Gallus gallus
TI:9031 None
   
LARP7_DANRE
ZFIN»
6.1
larp7 La-related protein 7 (La
ribonucleoprotein domain family member 7)		 Danio rerio
TI:7955 None
 
LARP7_MOUSE
Ensembl»
7.9
Larp7 La-related protein 7 (La
ribonucleoprotein domain family member 7)		 Mus musculus
TI:10090 None
 
LARP7_RAT
RGD»
10.5
Larp7 La-related protein 7 (La
ribonucleoprotein domain family member 7)		 Rattus norvegicus
TI:10116 None
 
Q9W362_DROME
FlyBase»
2.8
Larp7 La-related protein 7 (La
ribonucleoprotein domain family member 7)		 Drosophila melanogaster
TI:7227 None
 
LARP7_HUMAN
Ensembl»
9.7
LARP7 La-related protein 7 (La ribonucleoprotein domain family member
7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)		 Homo sapiens
TI:9606 None
 
LAR4_DROME
FlyBase»
3.1
Larp4B La-related protein Larp4B (La
ribonucleoprotein domain family member Larp4B)		 Drosophila melanogaster
TI:7227 None
 
O01806_CAEEL
WormBase»
1.5
ssb-1 Lupus La protein Caenorhabditis elegans
TI:6239 None
 
Q54TG6_DICDI
dictyBase»
0.5
DDB_G0281763 Lupus La protein Dictyostelium discoideum
TI:44689 None
 
LA_HUMAN
Ensembl»
15.2
SSB Lupus La protein (La autoantigen) (La
ribonucleoprotein) (Sjoegren syndrome type B antigen) (SS-B)		 Homo sapiens
TI:9606 None
 
Q7ZTI0_DANRE
ZFIN»
1.5
wu:fb17f11 Lupus La protein (Lupus La protein isoform X1) (Sjogren syndrome antigen
B (Autoantigen La)) (Small RNA-binding exonuclease protection factor La) (Ssb protein)		 Danio rerio
TI:7955 None
 
LA_MOUSE
Ensembl»
0.8
Ssb Lupus La protein homolog
(La autoantigen homolog) (La ribonucleoprotein)		 Mus musculus
TI:10090 None
 
LA_RAT
RGD»
7.8
Ssb Lupus La protein homolog
(La autoantigen homolog) (La ribonucleoprotein)		 Rattus norvegicus
TI:10116 None
 
SLF1_YEAST
SGD»
3.9
SLF1 Protein SLF1 Saccharomyces cerevisiae
TI:4932 None
 
SRO9_YEAST
SGD»
4.3
SRO9 RNA-binding protein SRO9 (Suppressor
of RHO3 protein 9)		 Saccharomyces cerevisiae
TI:4932 None
 
A0A8V0ZTE2_CHICK
Ensembl»
0.0
SSB Sjogren syndrome antigen B Gallus gallus
TI:9031 None
   
YLA3_SCHPO
PomBase»
1.5
SPAC1527.03 Uncharacterized HTH La-type
RNA-binding protein C1527.03		 Schizosaccharomyces pombe
TI:4896 None
 
Q54TE0_DICDI
dictyBase»
0.5
DDB_G0281835 Uncharacterized protein Dictyostelium discoideum
TI:44689 None