Collated Gene Ontology terms

Biological process: isopentenyl-diphosphate delta-isomerase activity(2003, 2005, 2007, 2008, 2011, 2013, 2022, 2025) isomerase activity(2025) catalytic activity(2025) metal ion binding(2025) hydrolase activity(2007, 2022, 2025) hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides(2019, 2023) intramolecular oxidoreductase activity(2025) hydrolase activity, acting on acid anhydrides(2025) magnesium ion binding(2011, 2019, 2022, 2025) manganese ion binding(2011, 2025)
zinc ion binding2019 nucleotide binding2025 nucleoside diphosphate phosphatase activity2025 helicase activity2025

Molecular function: isoprenoid biosynthetic process2003, 2011, 2013, 2025 isopentenyl diphosphate biosynthetic process2008, 2017, 2025 dimethylallyl diphosphate biosynthetic process2024, 2025 chlorophyll biosynthetic process2003, 2025 steroid biosynthetic process2025 lipid metabolic process2025 cholesterol biosynthetic process2005, 2025 sterol biosynthetic process2025 steroid metabolic process2025 cholesterol metabolic process2025
photosynthesis2025 farnesyl diphosphate biosynthetic process, mevalonate pathway2018, 2025 farnesyl diphosphate biosynthetic process2013, 2025 ergosterol biosynthetic process2022, 2025 zymosterol biosynthetic process2025 response to stilbenoid2011, 2025 geranylgeranyl diphosphate biosynthetic process2025 cholesterol biosynthetic process via lathosterol2025 cholesterol biosynthetic process via desmosterol2025 negative regulation of cholesterol biosynthetic process2011, 2013 isopentenyl diphosphate metabolic process2013 nucleotide metabolic process2022 nucleobase-containing compound metabolic process2007 flower development2008 DNA damage response2010

Cellular component: cytoplasm2018, 2023, 2025 cytosol2008, 2009, 2013, 2014, 2018, 2025 peroxisome2005, 2011, 2012, 2013, 2025 chloroplast2018, 2021, 2025 nucleus2009, 2018, 2025 mitochondrion2008, 2009, 2021 plastid2008, 2019 vacuole2022

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 2/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 39/39 
Archea: 2/8 
Bacteria: 11/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
IDI1_HUMAN
Ensembl»
5.2
IDI1 Isopentenyl-diphosphate Delta-isomerase 1 (EC 5.3.3.2) (Isopentenyl
pyrophosphate isomerase 1) (IPP isomerase 1) (IPPI1)		 Homo sapiens
TI:9606 None
 
IDI1_RAT
RGD»
7.8
Idi1 Isopentenyl-diphosphate Delta-isomerase 1 (EC 5.3.3.2) (Isopentenyl
pyrophosphate isomerase 1) (IPP isomerase 1) (IPPI1)		 Rattus norvegicus
TI:10116 None
 
IDI1_MOUSE
Ensembl»
8.6
Idi1 Isopentenyl-diphosphate Delta-isomerase 1 (EC 5.3.3.2) (Isopentenyl
pyrophosphate isomerase 1) (IPP isomerase 1) (IPPI1)		 Mus musculus
TI:10090 None
 
IDI1_ARATH
TAIR»
5.2
IPP1 Isopentenyl-diphosphate Delta-isomerase I, chloroplastic (EC 5.3.3.2)
(Isopentenyl pyrophosphate isomerase I) (IPP isomerase I)		 Arabidopsis thaliana
TI:3702 None
 
IDI2_ARATH
TAIR»
4.4
IPP2 Isopentenyl-diphosphate Delta-isomerase II, chloroplastic (EC 5.3.3.2)
(Isopentenyl pyrophosphate isomerase II) (IPP isomerase II)		 Arabidopsis thaliana
TI:3702 None
 
IDI2_HUMAN
Ensembl»
3.4
IDI2 Isopentenyl-diphosphate delta-isomerase 2 (EC 5.3.3.2) (Isopentenyl
pyrophosphate isomerase 2) (IPP isomerase 2) (IPPI2)		 Homo sapiens
TI:9606 None
 
IDI2_MOUSE
Ensembl»
4.1
Idi2 Isopentenyl-diphosphate delta-isomerase 2 (EC 5.3.3.2) (Isopentenyl
pyrophosphate isomerase 2) (IPP isomerase 2) (IPPI2)		 Mus musculus
TI:10090 None
 
IDI1_YEAST
SGD»
3.4
IDI1 Isopentenyl-diphosphate delta-isomerase (EC 5.3.3.2)
(Isopentenyl pyrophosphate isomerase) (IPP isomerase)		 Saccharomyces cerevisiae
TI:4932 None
 
IDI1_SCHPO
PomBase»
2.3
idi1 Isopentenyl-diphosphate delta-isomerase (EC 5.3.3.2)
(Isopentenyl pyrophosphate isomerasee) (IPP isomerase)		 Schizosaccharomyces pombe
TI:4896 None
 
A0A8I6AD97_RAT
RGD»
1.0
LOC120097764 isopentenyl-diphosphate Delta-isomerase
(EC 5.3.3.2)		 Rattus norvegicus
TI:10116 None
   
Q9VDC2_DROME
FlyBase»
2.0
Idi isopentenyl-diphosphate Delta-isomerase
(EC 5.3.3.2)		 Drosophila melanogaster
TI:7227 None
 
A0ABK0LU59_RAT
Ensembl»
2.0
Idi2 isopentenyl-diphosphate Delta-isomerase
(EC 5.3.3.2)		 Rattus norvegicus
TI:10116 None
   
A0A0G2JYZ4_RAT
RGD»
1.0
LOC102551575 isopentenyl-diphosphate Delta-isomerase
(EC 5.3.3.2)		 Rattus norvegicus
TI:10116 None
   
A0A8I6G9G8_RAT
RGD»
1.0
Idi2l2 isopentenyl-diphosphate Delta-isomerase
(EC 5.3.3.2)		 Rattus norvegicus
TI:10116 None
   
F1QVG2_DANRE
ZFIN»
1.0
idi1 isopentenyl-diphosphate Delta-isomerase
(EC 5.3.3.2)		 Danio rerio
TI:7955 None
 
IDI_DICDI
dictyBase»
1.0
ipi Isopentenyl-diphosphate Delta-isomerase (EC 5.3.3.2) (Isopentenyl
pyrophosphate isomerase) (IPP isomerase) (IPPI)		 Dictyostelium discoideum
TI:44689 None
 
IDI_ECOLI
EnsemblBacteria»
4.0
idi Isopentenyl-diphosphate Delta-isomerase (IPP isomerase) (EC
5.3.3.2) (IPP:DMAPP isomerase) (Isopentenyl pyrophosphate isomerase)		 Escherichia coli
TI:562 None
 
A0A8V0XUU8_CHICK
Ensembl»
0.0
IDI2 isopentenyl-diphosphate Delta-isomerase
(EC 5.3.3.2)		 Gallus gallus
TI:9031 None
   
A0ABK0LDG6_RAT
Ensembl»
0.0
LOC134484812 isopentenyl-diphosphate Delta-isomerase
(EC 5.3.3.2)		 Rattus norvegicus
TI:10116 None
   
A0ABK0LEV6_RAT
Ensembl»
0.0
LOC134482631 isopentenyl-diphosphate Delta-isomerase
(EC 5.3.3.2)		 Rattus norvegicus
TI:10116 None
   
A0ABK0LF56_RAT
Ensembl»
0.0
Idi2-ps1 isopentenyl-diphosphate Delta-isomerase
(EC 5.3.3.2)		 Rattus norvegicus
TI:10116 None
   
A0ABK0LF65_RAT
Ensembl»
0.0
LOC134482634 isopentenyl-diphosphate Delta-isomerase
(EC 5.3.3.2)		 Rattus norvegicus
TI:10116 None
   
A0ABK0LJQ1_RAT
Ensembl»
0.0
LOC102550988 isopentenyl-diphosphate Delta-isomerase
(EC 5.3.3.2)		 Rattus norvegicus
TI:10116 None
   
A0ABK0LRA8_RAT
Ensembl»
0.0
Idi2l3 isopentenyl-diphosphate Delta-isomerase
(EC 5.3.3.2)		 Rattus norvegicus
TI:10116 None
   
A0ABK0LVT8_RAT
Ensembl»
0.0
Idi2l2 isopentenyl-diphosphate Delta-isomerase
(EC 5.3.3.2)		 Rattus norvegicus
TI:10116 None
   
G5EFQ1_CAEEL
WormBase»
1.0
idi-1 isopentenyl-diphosphate Delta-isomerase
(EC 5.3.3.2)		 Caenorhabditis elegans
TI:6239 None
 
YFCD_ECOLI
EnsemblBacteria»
1.3
yfcD Uncharacterized Nudix hydrolase
YfcD (EC 3.6.-.-)		 Escherichia coli
TI:562 None
 
Q55D56_DICDI
dictyBase»
1.0
DDB_G0269784 Nudix hydrolase domain-containing protein Dictyostelium discoideum
TI:44689 None