Collated Gene Ontology terms

Biological process: methionine-tRNA ligase activity(2005, 2006, 2007, 2009, 2010, 2013, 2014, 2015, 2016, 2023, 2025) ATP binding(2004, 2007, 2009, 2025) ligase activity(2025) nucleotide binding(2025) aminoacyl-tRNA ligase activity(2025) tRNA binding(2025) metal ion binding(2025) RNA binding(2025) tyrosine-tRNA ligase activity(2025) magnesium ion binding(2010)
isoleucine-tRNA ligase activity2025

Molecular function: methionyl-tRNA aminoacylation2005, 2006, 2007, 2013, 2015, 2016, 2023, 2025 tRNA aminoacylation for protein translation2023, 2025 translation2025 tyrosyl-tRNA aminoacylation2025 plant ovule development2005 mitochondrial translation2009

Cellular component: mitochondrion2005, 2009, 2013, 2016, 2017, 2018, 2021, 2024, 2025 mitochondrial matrix2006, 2013, 2018, 2025 cytoplasm2015, 2017, 2025 chloroplast2005, 2018, 2021, 2025 chloroplast stroma2021, 2025 ciliary plasm2017 plasma membrane2010 apicoplast2015

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 0/1 
Porifera: 0/0 
Choanoflagellates+: 15/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 4/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 38/39 
Archea: 0/8 
Bacteria: 20/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
SYMM_HUMAN
Ensembl»
4.4
MARS2 Methionine--tRNA ligase, mitochondrial (EC 6.1.1.10) (Methionyl-tRNA
synthetase 2) (Mitochondrial methionyl-tRNA synthetase) (MtMetRS)		 Homo sapiens
TI:9606 None
 
SYMM_ARATH
TAIR»
2.6
OVA1 Methionine--tRNA ligase, chloroplastic/mitochondrial (EC 6.1.1.10) (Methionyl-tRNA
synthetase) (AtcpMetRS) (MetRS) (Protein OVULE ABORTION 1)		 Arabidopsis thaliana
TI:3702 None
 
SYMM_DROME
FlyBase»
3.8
MetRS-m Methionine--tRNA ligase, mitochondrial (EC
6.1.1.10) (Mitochondrial methionyl-tRNA synthetase) (MtMetRS)		 Drosophila melanogaster
TI:7227 None
 
SYMM_MOUSE
Ensembl»
2.0
Mars2 Methionine--tRNA ligase, mitochondrial (EC 6.1.1.10) (Methionyl-tRNA
synthetase 2) (Mitochondrial methionyl-tRNA synthetase) (MtMetRS)		 Mus musculus
TI:10090 None
 
SYMM_YEAST
SGD»
2.6
MSM1 Methionine--tRNA ligase, mitochondrial (EC
6.1.1.10) (Methionyl-tRNA synthetase) (MetRS)		 Saccharomyces cerevisiae
TI:4932 None
 
B3KYC0_CAEEL
WormBase»
1.0
mars-2 Methionine--tRNA ligase, mitochondrial (EC
6.1.1.10) (Mitochondrial methionyl-tRNA synthetase)		 Caenorhabditis elegans
TI:6239 None
 
SYMM_DICDI
dictyBase»
2.0
mmetS Probable methionine--tRNA ligase, mitochondrial (EC
6.1.1.10) (Mitochondrial methionyl-tRNA synthetase) (MtMetRS)		 Dictyostelium discoideum
TI:44689 None
 
SYMM_SCHPO
PomBase»
2.1
SPAC27E2.06c Probable methionine--tRNA ligase, mitochondrial (EC
6.1.1.10) (Mitochondrial methionyl-tRNA synthetase) (MtMetRS)		 Schizosaccharomyces pombe
TI:4896 None
 
A0A8M9Q9I2_DANRE
ZFIN»
0.0
mars2 Methionine--tRNA ligase, mitochondrial Danio rerio
TI:7955 None
   
D4A9V7_RAT
RGD»
2.0
Mars2 Methionine--tRNA ligase, mitochondrial (EC 6.1.1.10)
(Methionyl-tRNA synthetase 2) (Mitochondrial methionyl-tRNA synthetase)		 Rattus norvegicus
TI:10116 None
   
F1P137_CHICK
Ensembl»
1.0
Methionine--tRNA ligase, mitochondrial (EC 6.1.1.10)
(Methionyl-tRNA synthetase 2) (Mitochondrial methionyl-tRNA synthetase)		 Gallus gallus
TI:9031 None