Collated Gene Ontology terms

Biological process: NADH pyrophosphatase activity(2011, 2017, 2019, 2024) metal ion binding(2024) hydrolase activity(2019, 2024) NAD+ diphosphatase activity(2005, 2013, 2019, 2024) RNA NAD-cap (NMN-forming) hydrolase activity(2019, 2024) zinc ion binding(2019, 2022, 2024) magnesium ion binding(2019, 2024) phosphodiesterase decapping endonuclease activity(2021, 2024) manganese ion binding(2012, 2024) protein homodimerization activity(2015)
ADP-ribose diphosphatase activity2024

Molecular function: NADP catabolic process2017, 2019, 2024 NAD catabolic process2017, 2019, 2024 NADH metabolic process2013, 2017, 2024 NAD-cap decapping2019, 2021, 2022, 2024 methylguanosine-cap decapping2021, 2024 mRNA catabolic process2019, 2024 circadian regulation of gene expression2021, 2024 proteasome-mediated ubiquitin-dependent protein catabolic process2021 piecemeal microautophagy of the nucleus2021 mRNA stabilization2019
RNA decapping2022 NAD biosynthesis via nicotinamide riboside salvage pathway2024

Cellular component: peroxisome2013, 2019, 2022, 2024 cytoplasm2018, 2019, 2024 nucleus2009, 2010, 2024 chloroplast2009, 2024 cytosol2009, 2018, 2024 membrane2024 plasma membrane2010 peroxisomal matrix2015

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 1/3 
Arthropods: 1/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 13/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 3/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 37/39 
Archea: 1/8 
Bacteria: 14/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
NPY1_SCHPO
PomBase»
2.5
SPBC1778.03c NAD-capped RNA hydrolase (DeNADding enzyme) (EC
3.6.1.-) (Probable NADH pyrophosphatase) (EC 3.6.1.22)		 Schizosaccharomyces pombe
TI:4896 None
 
NPY1_YEAST
SGD»
5.8
NPY1 NAD-capped RNA hydrolase NPY1 (DeNADding enzyme
NPY1) (EC 3.6.1.-) (NADH pyrophosphatase) (EC 3.6.1.22)		 Saccharomyces cerevisiae
TI:4932 None
 
NUD12_HUMAN
Ensembl»
11.9
NUDT12 NAD-capped RNA hydrolase NUDT12 (DeNADding enzyme NUDT12) (EC 3.6.1.-) (NADH pyrophosphatase
NUDT12) (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12)		 Homo sapiens
TI:9606 None
 
NUD12_MOUSE
Ensembl»
6.8
Nudt12 NAD-capped RNA hydrolase NUDT12 (DeNADding enzyme NUDT12) (EC 3.6.1.-) (NADH pyrophosphatase
NUDT12) (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12)		 Mus musculus
TI:10090 None
 
A0A8M9Q9P3_DANRE
CTD»
2.0
nudt12 NAD-capped RNA hydrolase NUDT12 (EC 3.6.1.22) (NADH
pyrophosphatase NUDT12) (Nucleoside diphosphate-linked moiety X motif 12)		 Danio rerio
TI:7955 None
   
D4A2H8_RAT
RGD»
8.0
Nudt12 NAD-capped RNA hydrolase NUDT12 (EC 3.6.1.22) (NADH
pyrophosphatase NUDT12) (Nucleoside diphosphate-linked moiety X motif 12)		 Rattus norvegicus
TI:10116 None
   
E1C2E5_CHICK
Ensembl»
2.0
NUDT12 NAD-capped RNA hydrolase NUDT12 (EC 3.6.1.22) (NADH
pyrophosphatase NUDT12) (Nucleoside diphosphate-linked moiety X motif 12)		 Gallus gallus
TI:9031 None
   
NUDC_ECOLI
EnsemblBacteria»
10.0
nudC NAD-capped RNA hydrolase NudC (DeNADding enzyme
NudC) (EC 3.6.1.-) (NADH pyrophosphatase) (EC 3.6.1.22)		 Escherichia coli
TI:562 None
 
NPY1_CAEEL
WormBase»
2.0
ndx-9 NAD-capped RNA hydrolase ndx-9 (DeNADding enzyme ndx-9) (EC
3.6.1.-) (NADH pyrophosphatase) (EC 3.6.1.22) (Nudix hydrolase 9)		 Caenorhabditis elegans
TI:6239 None
 
NUD17_DANRE
ZFIN»
2.0
nudt17 Nucleoside diphosphate-linked moiety X motif
17 (Nudix motif 17) (EC 3.6.1.-)		 Danio rerio
TI:7955 None
 
NUD17_HUMAN
Ensembl»
2.0
NUDT17 Nucleoside diphosphate-linked moiety X motif
17 (Nudix motif 17) (EC 3.6.1.-)		 Homo sapiens
TI:9606 None
 
NUD17_MOUSE
Ensembl»
0.0
Nudt17 Nucleoside diphosphate-linked moiety X motif
17 (Nudix motif 17) (EC 3.6.1.-)		 Mus musculus
TI:10090 None
 
Q54N32_DICDI
dictyBase»
2.0
DDB_G0285539 Nucleoside diphosphate-linked moiety X motif 17 Dictyostelium discoideum
TI:44689 None
 
D3ZCT0_RAT
RGD»
2.0
Nudt17 Nudix hydrolase 17 Rattus norvegicus
TI:10116 None
   
NUD19_ARATH
TAIR»
0.0
NUDT19 Nudix hydrolase 19, chloroplastic (AtNUDT19) (NAD-capped RNA hydrolase NUDT19)
(DeNADding enzyme NUDT19) (EC 3.6.1.-) (NADH pyrophosphatase NUDT19) (EC 3.6.1.22)		 Arabidopsis thaliana
TI:3702 None