Collated Gene Ontology terms

Biological process: protein homodimerization activity(2011, 2015, 2025) phosphatidylinositol-4-phosphate binding(2017, 2025) identical protein binding(2025) protein serine/threonine kinase activity(2025) sterol binding(2024) phospholipid binding(2019, 2021, 2025) phosphatidylinositol-3,4,5-trisphosphate binding(2017, 2025) lipid binding(2020, 2025) molecular carrier activity(2025) chromatin binding(2021)
metal ion binding2025 kinase activity2025 intramolecular lyase activity2025 GTPase activator activity2025

Molecular function: endosome organization2011, 2015, 2021, 2022, 2025 retrograde transport, endosome to Golgi2011, 2017, 2025 receptor recycling2011, 2017, 2025 defense response to bacterium2012, 2025 intracellular signal transduction2025 vesicle fusion to plasma membrane2021, 2025 septum digestion after cytokinesis2015, 2025 exocytosis2013, 2025 budding cell apical bud growth2013, 2025 actin filament organization2020, 2025
mitotic chromosome condensation2022 regulation of cell differentiation2017 cell division2025 vacuole organization2014 signal transduction2025 phosphatidylinositol biosynthetic process2025 filamentous growth2025 cranial skeletal system development2022 cilium assembly2022 chemotaxis to cAMP2017 cellular response to xenobiotic stimulus2014

Cellular component: recycling endosome2011, 2015, 2017, 2025 early endosome2011, 2017, 2025 trans-Golgi network2011, 2017, 2025 cytosol2017, 2023, 2025 Golgi apparatus2024, 2025 clathrin-coated vesicle2011, 2025 cytoplasmic vesicle2025 membrane2024, 2025 plasma membrane2017, 2018, 2021, 2023, 2025 cellular bud neck2013, 2018, 2025
Golgi membrane2016, 2025 perinuclear endoplasmic reticulum2018 cellular bud2021, 2025 cytoplasm2018, 2025 condensin complex2025 condensed chromosome2021 chromatin2022 cell tip2009, 2014, 2025 cell division site2009, 2014, 2025 site of polarized growth2013 medial cortex2004, 2025 cell cortex of cell tip2004, 2025 mating projection tip2018 endosome2021 endoplasmic reticulum2025 cell periphery2025 cell leading edge2021

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 6/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 1/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 38/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
Q8VYJ6_ARATH
TAIR»
2.3
SWAP70 At2g30880/F7F1.9 (Pleckstrin homology
(PH) domain-containing protein)		 Arabidopsis thaliana
TI:3702 None
 
PKHJ1_DANRE
ZFIN»
1.5
plekhj1 Pleckstrin homology domain-containing family J member
1 (PH domain-containing family J member 1)		 Danio rerio
TI:7955 None
 
Q0P3X0_DANRE
ZFIN»
3.1
pheta2 Sesquipedalian (Ses) (PH
domain-containing endocytic trafficking adaptor)		 Danio rerio
TI:7955 None
 
Q7SXV5_DANRE
ZFIN»
1.5
plekha3 Pleckstrin homology domain-containing family
A member 3 (Zgc:63749)		 Danio rerio
TI:7955 None
 
Q54CZ1_DICDI
dictyBase»
3.1
DDB_G0292622 PH domain-containing protein Dictyostelium discoideum
TI:44689 None
 
Q54Y24_DICDI
dictyBase»
1.5
DDB_G0278461 PH domain-containing protein Dictyostelium discoideum
TI:44689 None
 
Y4775_DICDI
dictyBase»
2.3
DDB_G0274775 PH domain-containing protein DDB_G0274775 Dictyostelium discoideum
TI:44689 None
 
Q9VMI6_DROME
FlyBase»
3.3
IPIP Inositol phosphatase interacting protein, isoform A (Inositol phosphatase interacting
protein, isoform B) (Inositol phosphatase interacting protein, isoform D)		 Drosophila melanogaster
TI:7227 None
 
A0A8V0YC83_CHICK
Ensembl»
1.5
FAM109B Sesquipedalian (Ses) (PH
domain-containing endocytic trafficking adaptor)		 Gallus gallus
TI:9031 None
   
A0A8V0ZTB0_CHICK
Ensembl»
0.0
PLEKHA3 Pleckstrin homology domain containing A3 Gallus gallus
TI:9031 None
   
A0A8V1A905_CHICK
Ensembl»
1.5
FAM109A Sesquipedalian (Ses) (PH
domain-containing endocytic trafficking adaptor)		 Gallus gallus
TI:9031 None
   
PKHJ1_CHICK
Ensembl»
1.5
PLEKHJ1 Pleckstrin homology domain-containing family J member
1 (PH domain-containing family J member 1)		 Gallus gallus
TI:9031 None
 
PKHA3_HUMAN
Ensembl»
4.8
PLEKHA3 Pleckstrin homology domain-containing family A member 3 (PH domain-containing family A
member 3) (Phosphatidylinositol-four-phosphate adapter protein 1) (FAPP-1) (Phosphoinositol 4-phosphate adapter protein 1)		 Homo sapiens
TI:9606 None
 
PKHJ1_HUMAN
Ensembl»
1.5
PLEKHJ1 Pleckstrin homology domain-containing family J member 1 (PH
domain-containing family J member 1) (Guanine nucleotide-releasing protein x)		 Homo sapiens
TI:9606 None
 
SESQ1_HUMAN
Ensembl»
4.7
PHETA1 Sesquipedalian-1 (Ses1) (27 kDa inositol polyphosphate phosphatase-interacting protein
A) (IPIP27A) (PH domain-containing endocytic trafficking adaptor 1)		 Homo sapiens
TI:9606 None
 
SESQ2_HUMAN
Ensembl»
4.7
PHETA2 Sesquipedalian-2 (Ses2) (27 kDa inositol polyphosphate phosphatase interacting
protein B) (IPIP27B) (PH domain-containing endocytic trafficking adaptor 2)		 Homo sapiens
TI:9606 None
 
PKHA3_MOUSE
Ensembl»
3.0
Plekha3 Pleckstrin homology domain-containing family A member 3 (PH domain-containing family A
member 3) (Phosphatidylinositol-four-phosphate adapter protein 1) (FAPP-1) (Phosphoinositol 4-phosphate adapter protein 1)		 Mus musculus
TI:10090 None
 
PKHJ1_MOUSE
Ensembl»
1.5
Plekhj1 Pleckstrin homology domain-containing family J member 1 (PH
domain-containing family J member 1) (Guanine nucleotide-releasing protein x)		 Mus musculus
TI:10090 None
 
SESQ1_MOUSE
Ensembl»
3.5
Pheta1 Sesquipedalian-1 (Ses1) (27 kDa inositol polyphosphate phosphatase interacting
protein A) (IPIP27A) (PH domain-containing endocytic trafficking adaptor 1)		 Mus musculus
TI:10090 None
 
SESQ2_MOUSE
AG»
3.5
Pheta2 Sesquipedalian-2 (Ses2) (27 kDa inositol polyphosphate phosphatase interacting
protein B) (IPIP27B) (PH domain-containing endocytic trafficking adaptor 2)		 Mus musculus
TI:10090 None
 
A0A8I5ZL55_RAT
RGD»
1.5
Plekha3 Sesquipedalian (Ses) (PH
domain-containing endocytic trafficking adaptor)		 Rattus norvegicus
TI:10116 None
   
A0ABK0LEN1_RAT
Ensembl»
0.0
Plekhj1 Sesquipedalian (Ses) (PH
domain-containing endocytic trafficking adaptor)		 Rattus norvegicus
TI:10116 None
   
D4A374_RAT
RGD»
3.5
Pheta2 Sesquipedalian (Ses) (PH
domain-containing endocytic trafficking adaptor)		 Rattus norvegicus
TI:10116 None
   
SESQ1_RAT
RGD»
3.5
Pheta1 Sesquipedalian-1 (Ses1) (27 kDa inositol polyphosphate phosphatase interacting
protein A) (IPIP27A) (PH domain-containing endocytic trafficking adaptor 1)		 Rattus norvegicus
TI:10116 None
 
BOI1_YEAST
SGD»
5.5
BOI1 BEM1-interacting protein 1
(Growth inhibitory protein 7)		 Saccharomyces cerevisiae
TI:4932 None
 
BOI2_YEAST
SGD»
6.0
BOI2 BEM1-interacting protein 2 Saccharomyces cerevisiae
TI:4932 None
 
POB1_SCHPO
PomBase»
2.8
pob1 Protein pob1 (BOI protein homolog) Schizosaccharomyces pombe
TI:4896 None