Collated Gene Ontology terms

Biological process: serine-type endopeptidase activity(2003, 2025) oligopeptidase activity(2010, 2020, 2025) serine-type peptidase activity(2003, 2025) peptidase activity(2025) hydrolase activity(2025) metallocarboxypeptidase activity(2024, 2025) serine hydrolase activity(2021) peptide binding(2007, 2025) endopeptidase activity(2008, 2025) cysteine-type peptidase activity(2025)
carboxylesterase activity2022

Molecular function: proteolysis2003, 2009, 2025 angiotensin maturation2024, 2025 response to lithium ion2021, 2025 regulation of signal transduction2023, 2025 protein catabolic process2007, 2025 regulation of gene expression2024 defense response to fungus2020

Cellular component: cytosol2011, 2020, 2023, 2024, 2025 cytoplasm2003, 2009, 2016, 2017, 2018, 2023, 2025 nucleus2000, 2009, 2025 extracellular region2024, 2025 chloroplast2018, 2021 plasma membrane2010 mitochondrion2019 membrane2014

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 1/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 5/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 2/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 39/39 
Archea: 1/8 
Bacteria: 8/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
PPCE_MOUSE
Ensembl»
4.4
Prep Prolyl endopeptidase (PE) (EC
3.4.21.26) (Post-proline cleaving enzyme)		 Mus musculus
TI:10090 None
 
PPCE_RAT
RGD»
4.4
Prep Prolyl endopeptidase (PE) (EC
3.4.21.26) (Post-proline cleaving enzyme) (rPop)		 Rattus norvegicus
TI:10116 None
 
PPCE_HUMAN
Ensembl»
3.2
PREP Prolyl endopeptidase (PE) (EC
3.4.21.26) (Post-proline cleaving enzyme)		 Homo sapiens
TI:9606 None
 
A0A8V0YJW4_CHICK
Ensembl»
0.5
PREP Prolyl endopeptidase (EC 3.4.21.-) Gallus gallus
TI:9031 None
   
PPCE_DICDI
dictyBase»
3.7
prep Prolyl endopeptidase (PE) (EC
3.4.21.26) (POase) (Post-proline cleaving enzyme)		 Dictyostelium discoideum
TI:44689 None
 
F4I2A0_ARATH
TAIR»
0.5
At1g76140 Prolyl endopeptidase (EC 3.4.21.-) Arabidopsis thaliana
TI:3702 None
 
Q9VKW5_DROME
FlyBase»
1.8
Dmel\CG5355 Prolyl endopeptidase (EC 3.4.21.-) Drosophila melanogaster
TI:7227 None
 
Q503E2_DANRE
ZFIN»
0.5
prep Prolyl endopeptidase (EC 3.4.21.-) Danio rerio
TI:7955 None
 
Q9V9P5_DROME
FlyBase»
1.0
lincRNA.224 Prolyl endopeptidase (EC 3.4.21.-) Drosophila melanogaster
TI:7227 None
 
A0A1P8APL9_ARATH
TAIR»
0.8
POQR Prolyl endopeptidase (EC 3.4.21.-) Arabidopsis thaliana
TI:3702 None