Collated Gene Ontology terms

Biological process: deoxyhypusine monooxygenase activity(2006, 2008, 2011, 2013, 2018, 2020, 2024) oxidoreductase activity(2020, 2024) metal ion binding(2008, 2024) monooxygenase activity(2024) iron ion binding(2011, 2018, 2024) lyase activity(2024) zinc ion binding(2021) ATP hydrolysis activity(2024)

Molecular function: peptidyl-lysine modification to peptidyl-hypusine2006, 2008, 2018, 2019, 2024 signal transduction2024 microtubule cytoskeleton organization2013, 2024 single-species biofilm formation on inanimate substrate2014 response to radiation2016 response to antibiotic2010 regulation of cytoplasmic translation2017 iron-sulfur cluster assembly2005 filamentous growth of a population of unicellular organisms in response to neutral pH2014 filamentous growth of a population of unicellular organisms2014
cytoplasmic translation2021 cell population proliferation2011 apoptotic process2024 DNA damage response2010

Cellular component: phycobilisome2024 cytoplasm2016, 2017, 2018, 2024 nucleus2009, 2018, 2024 membrane2024 cytosol2009, 2013, 2019 mitochondrion2005, 2021 endoplasmic reticulum membrane2010, 2024 small ribosomal subunit2024 nucleolus2021 mitochondrial ribosome2024
fungal biofilm matrix2022 extrinsic component of endoplasmic reticulum membrane2024 endoplasmic reticulum2024 chloroplast2021 Golgi apparatus2012

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 2/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 37/39 
Archea: 3/8 
Bacteria: 12/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
HEAT4_HUMAN
Ensembl»
0.5
HEATR4 HEAT repeat-containing protein 4 Homo sapiens
TI:9606 None
 
DOHH_ARATH
TAIR»
1.0
At3g58180 Deoxyhypusine hydroxylase (DOHH) (EC
1.14.99.29) (Deoxyhypusine dioxygenase) (Deoxyhypusine monooxygenase)		 Arabidopsis thaliana
TI:3702 None
 
DOHH_HUMAN
Ensembl»
3.7
DOHH Deoxyhypusine hydroxylase (hDOHH) (EC 1.14.99.29) (Deoxyhypusine
dioxygenase) (Deoxyhypusine monooxygenase) (HEAT-like repeat-containing protein 1)		 Homo sapiens
TI:9606 None
 
YIBA_ECOLI
EnsemblBacteria»
2.9
yibA Protein YibA Escherichia coli
TI:562 None
 
DOHH_MOUSE
Ensembl»
1.5
Dohh Deoxyhypusine hydroxylase (DOHH) (EC
1.14.99.29) (Deoxyhypusine dioxygenase) (Deoxyhypusine monooxygenase)		 Mus musculus
TI:10090 None
 
DOHH_YEAST
SGD»
2.9
LIA1 Deoxyhypusine hydroxylase (DOHH) (EC 1.14.99.29) (Deoxyhypusine dioxygenase)
(Deoxyhypusine monooxygenase) (Ligand of eIF5A protein 1)		 Saccharomyces cerevisiae
TI:4932 None
 
Q94K48_ARATH
TAIR»
1.3
At3g62530 ARM repeat superfamily
protein (Uncharacterized protein At3g62530)		 Arabidopsis thaliana
TI:3702 None
 
DOHH_DICDI
dictyBase»
2.0
dohh-1; dohh-2 Deoxyhypusine hydroxylase (DOHH) (EC
1.14.99.29) (Deoxyhypusine dioxygenase) (Deoxyhypusine monooxygenase)		 Dictyostelium discoideum
TI:44689 None
 
DOHH_DROME
FlyBase»
3.1
nero Deoxyhypusine hydroxylase (DOHH) (EC
1.14.99.29) (Deoxyhypusine dioxygenase) (Deoxyhypusine monooxygenase)		 Drosophila melanogaster
TI:7227 None
 
DOHH_CAEEL
WormBase»
2.0
dohh-1 Deoxyhypusine hydroxylase (DOHH) (EC
1.14.99.29) (Deoxyhypusine dioxygenase) (Deoxyhypusine monooxygenase)		 Caenorhabditis elegans
TI:6239 None
 
DOHH_CHICK
Ensembl»
2.0
DOHH Deoxyhypusine hydroxylase (DOHH) (EC
1.14.99.29) (Deoxyhypusine dioxygenase) (Deoxyhypusine monooxygenase)		 Gallus gallus
TI:9031 None
 
DOHH_DANRE
ZFIN»
2.0
dohh Deoxyhypusine hydroxylase (DOHH) (EC
1.14.99.29) (Deoxyhypusine dioxygenase) (Deoxyhypusine monooxygenase)		 Danio rerio
TI:7955 None
 
DOHH_RAT
RGD»
3.0
Dohh Deoxyhypusine hydroxylase (DOHH) (EC
1.14.99.29) (Deoxyhypusine dioxygenase) (Deoxyhypusine monooxygenase)		 Rattus norvegicus
TI:10116 None
 
DOHH_SCHPO
PomBase»
1.5
lia1 Deoxyhypusine hydroxylase (DOHH) (EC
1.14.99.29) (Deoxyhypusine dioxygenase) (Deoxyhypusine monooxygenase)		 Schizosaccharomyces pombe
TI:4896 None
 
A0A8M3AJZ3_DANRE
CTD»
0.5
si:dkey-13p1.3 HEAT repeat-containing protein 4 Danio rerio
TI:7955 None
   
D3ZSB9_RAT
RGD»
0.5
Heatr4 HEAT repeat containing 4 Rattus norvegicus
TI:10116 None
   
E9Q357_MOUSE
Ensembl»
0.0
Heatr4 HEAT repeat containing 4 Mus musculus
TI:10090 None