Biological process: ATP binding^{(2014, 2024)} helicase activity^{(2006, 2007, 2021, 2024)} hydrolase activity⁽²⁰²⁴⁾ nucleic acid binding⁽²⁰²⁴⁾ ATP hydrolysis activity^{(2009, 2023, 2024)} RNA helicase activity^{(2006, 2007, 2013, 2017, 2019, 2022, 2023, 2024)} 3'-5' DNA helicase activity^{(2012, 2017, 2019, 2024)} DNA binding⁽²⁰²⁴⁾ single-stranded 3'-5' DNA helicase activity^{(2020, 2022, 2024)} identical protein binding⁽²⁰²⁴⁾
± 13 DNA-directed DNA polymerase activity²⁰²⁴ isomerase activity²⁰²⁴ hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides²⁰²⁴ S-adenosylmethionine-dependent methyltransferase activity²⁰²⁴ catalytic activity, acting on DNA²⁰²⁴ RNA binding^{2014, 2024} single-stranded DNA helicase activity^{2010, 2012, 2024} DNA helicase activity²⁰²⁴ ATPase binding^{2012, 2024} mRNA binding^{2018, 2021} endonuclease activity²⁰²⁴ polyubiquitin modification-dependent protein binding²⁰²⁴ oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor²⁰²⁴

Molecular function: mRNA processing^{2016, 2024} RNA catabolic process²⁰²³ spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)^{2013, 2022, 2023, 2024} DNA duplex unwinding^{2012, 2022, 2024} rescue of stalled ribosome^{2021, 2023, 2024} ribosome-associated ubiquitin-dependent protein catabolic process^{2021, 2022, 2024} ribosome disassembly^{2021, 2022, 2023, 2024} mRNA splicing, via spliceosome^{2006, 2010, 2011, 2013, 2016, 2019, 2020, 2022, 2024} DNA repair²⁰²⁴ DNA dealkylation involved in DNA repair^{2012, 2022, 2024}
± 48 double-strand break repair via synthesis-dependent strand annealing^{2022, 2024} double-strand break repair via alternative nonhomologous end joining^{2022, 2024} DNA double-strand break processing involved in repair via single-strand annealing^{2022, 2024} double-strand break repair via homologous recombination^{2013, 2024} positive regulation of double-strand break repair via homologous recombination^{2022, 2024} RNA splicing^{2006, 2024} DNA biosynthetic process²⁰²⁴ DNA-templated DNA replication²⁰²⁴ nervous system development²⁰²⁴ DNA conformation change²⁰²⁴ regulation of translation^{2006, 2013, 2024} cytoplasmic translation^{2013, 2017, 2024} resolution of meiotic recombination intermediates^{2012, 2024} regulation of alternative mRNA splicing, via spliceosome^{2006, 2009, 2016} spliceosomal conformational changes to generate catalytic conformation^{2005, 2024} oogenesis²⁰⁰⁶ intron homing²⁰²⁴ intracellular mRNA localization²⁰⁰⁶ intein-mediated protein splicing²⁰²⁴ germarium-derived oocyte fate determination^{2006, 2007} ventral cord development²⁰¹⁵ vegetative to reproductive phase transition of meristem²⁰¹⁶ ubiquitin-dependent protein catabolic process²⁰²¹ spermatogenesis²⁰¹⁶ ribosomal large subunit export from nucleus²⁰²¹ response to ionizing radiation²⁰²⁴ proteasome-mediated ubiquitin-dependent protein catabolic process²⁰²¹ positive regulation of DNA repair²⁰²⁴ polarity specification of dorsal/ventral axis²⁰⁰⁶ polarity specification of anterior/posterior axis²⁰⁰⁶ osteoblast differentiation²⁰¹⁷ oocyte karyosome formation²⁰⁰⁷ nucleobase-containing compound metabolic process²⁰¹⁴ mitotic cell cycle²⁰¹⁰ mitotic G2 DNA damage checkpoint signaling²⁰²⁴ meiotic cell cycle²⁰²⁴ maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)²⁰²¹ maturation of 5.8S rRNA²⁰²⁰ female meiosis chromosome segregation²⁰⁰⁷ endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)²⁰²¹ endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)²⁰²¹ double-strand break repair²⁰²⁴ defense response to virus²⁰²⁴ cis assembly of pre-catalytic spliceosome²⁰⁰⁶ chromatin organization²⁰²⁴ cell population proliferation²⁰¹² RNA splicing, via transesterification reactions²⁰⁰⁷ DNA metabolic process²⁰⁰²

Cellular component: nucleus^{2006, 2009, 2012, 2014, 2016, 2017, 2018, 2019, 2020, 2021, 2022, 2023, 2024} spliceosomal complex^{2002, 2004, 2006, 2007, 2014, 2016, 2020, 2024} cytosol^{2009, 2019, 2021, 2023, 2024} U5 snRNP^{2006, 2013, 2016, 2021, 2024} ribonucleoprotein complex²⁰²⁴ cytosolic ribosome^{2023, 2024} U4/U6 x U5 tri-snRNP complex^{2005, 2013, 2016, 2017, 2022, 2024} site of DNA damage^{2022, 2024} nucleoplasm^{2013, 2014, 2017, 2023, 2024} activating signal cointegrator 1 complex^{2016, 2024}
± 18 DNA repair complex^{2022, 2024} cytoplasm^{2018, 2023, 2024} U2-type precatalytic spliceosome^{2019, 2024} U2-type catalytic step 1 spliceosome^{2019, 2024} catalytic step 2 spliceosome^{2010, 2011, 2024} nuclear speck²⁰²⁴ membrane^{2014, 2017, 2024} chromosome²⁰²⁴ small nuclear ribonucleoprotein complex^{2006, 2014} post-mRNA release spliceosomal complex^{2016, 2024} single-stranded DNA-dependent ATP-dependent DNA helicase complex²⁰⁰² precatalytic spliceosome²⁰¹⁰ plasmodesma²⁰²¹ nucleolus²⁰²¹ nuclear body²⁰²⁴ cytoplasmic stress granule²⁰²⁰ RQC-trigger complex²⁰²³ BRCA1-A complex²⁰²⁴