Collated Gene Ontology terms

Biological process: heme binding(2011, 2019, 2020, 2024) metal ion binding(2024) oxidoreductase activity(2019, 2024) nitrite reductase (NO-forming) activity(2020, 2024) nitrate reductase (NADH) activity(2024) electron transfer activity(2005, 2006, 2007, 2009, 2013, 2014) enzyme binding(2010, 2024) enzyme activator activity(2006, 2024) cytochrome-b5 reductase activity, acting on NAD(P)H(2017, 2024) 2 iron, 2 sulfur cluster binding(2024)
ubiquinol-cytochrome-c reductase activity2005 stearoyl-CoA 9-desaturase activity2002 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen2024 linoleoyl-CoA desaturase activity2024 fatty acid alpha-hydroxylase activity2020 cytochrome-c oxidase activity2003

Molecular function: sterol biosynthetic process2013, 2020, 2021 nitric oxide biosynthetic process2020, 2024 very long-chain fatty acid biosynthetic process2019, 2024 ergosterol biosynthetic process2005, 2006, 2014 cellular response to xenobiotic stimulus2008, 2024 alkane biosynthetic process2012, 2024 xenobiotic metabolic process2020 response to oxidative stress2020 proton transmembrane transport2024 fatty acid metabolic process2004, 2021
electron transport chain2009 tryptophan catabolic process to kynurenine2024 tryptophan catabolic process2024 translation2021 sensory perception of chemical stimulus2024 response to cadmium ion2007 post-transcriptional regulation of gene expression2016

Cellular component: membrane2013, 2014, 2019, 2021, 2024 intracellular membrane-bounded organelle2023, 2024 endoplasmic reticulum membrane2006, 2007, 2013, 2020, 2021, 2023, 2024 endoplasmic reticulum2007, 2009, 2017, 2018, 2020, 2021, 2024 mitochondrial outer membrane2013, 2015, 2016, 2019, 2020, 2024 nitric-oxide synthase complex2020, 2024 stromule2008, 2024 mitochondrion2007, 2009, 2014, 2024 cytosol2011, 2018, 2019, 2023, 2024 chloroplast outer membrane2008, 2024
cytoplasm2017, 2024 plastid2019 plasma membrane2021, 2024 perinuclear region of cytoplasm2012, 2024 nuclear envelope2017 mitochondrial inner membrane2005, 2009 ciliary pocket2017 plant-type vacuole2021 nucleus2017 mitochondrial membrane2024 food vacuole2013 endomembrane system2014 chloroplast thylakoid membrane2021 chloroplast membrane2024 chloroplast2024

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 4/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 36/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
A8WGS0_DANRE
ZFIN»
2.9
cyb5 Cyb5a protein (Cytochrome b5 isoform
X1) (Cytochrome b5 type A (microsomal))		 Danio rerio
TI:7955 None
 
CYB5C_ARATH
TAIR»
0.0
CYTB5-C Cytochrome B5 isoform C (AtCb5-C) Arabidopsis thaliana
TI:3702 None
 
CYB5D_ARATH
TAIR»
0.0
CYTB5-D Cytochrome B5 isoform D (AtCb5-D)
(Cytochrome b5 isoform B) (AtCb5-B)		 Arabidopsis thaliana
TI:3702 None
 
CYP5F_ARATH
TAIR»
0.0
CB5LP Cytochrome B5-like protein (AtCb5LP)
(Cytochrome b5 isoform F) (AtCb5-F)		 Arabidopsis thaliana
TI:3702 None
 
A0A8I6AFG0_RAT
RGD»
0.0
ENSRNOG00000064959 Cytochrome b5
heme-binding domain-containing protein		 Rattus norvegicus
TI:10116 None
   
A0A8V0XM97_CHICK
Ensembl»
0.0
Cytochrome b5
heme-binding domain-containing protein		 Gallus gallus
TI:9031 None
   
CYB5_CHICK
Ensembl»
0.5
CYB5A Cytochrome b5 Gallus gallus
TI:9031 None
 
CYB5_MOUSE
Ensembl»
1.9
Cyb5a Cytochrome b5 Mus musculus
TI:10090 None
 
CYB5_RAT
RGD»
2.7
Cyb5a Cytochrome b5 Rattus norvegicus
TI:10116 None
 
CYB5_YEAST
SGD»
2.6
CYB5 Cytochrome b5 Saccharomyces cerevisiae
TI:4932 None
 
O01816_CAEEL
WormBase»
0.5
cytb-5.2 Cytochrome b5
heme-binding domain-containing protein		 Caenorhabditis elegans
TI:6239 None
 
Q54FQ6_DICDI
dictyBase»
0.5
DDB_G0290697 Cytochrome b5
heme-binding domain-containing protein		 Dictyostelium discoideum
TI:44689 None
 
Q54UZ7_DICDI
dictyBase»
0.5
DDB_G0280747 Cytochrome b5
heme-binding domain-containing protein		 Dictyostelium discoideum
TI:44689 None
 
Q55DX6_DICDI
dictyBase»
0.5
DDB_G0269488 Cytochrome b5
heme-binding domain-containing protein		 Dictyostelium discoideum
TI:44689 None
 
Q8T2Q1_DICDI
dictyBase»
0.5
DDB_G0275147 Cytochrome b5
heme-binding domain-containing protein		 Dictyostelium discoideum
TI:44689 None
 
Q93315_CAEEL
WormBase»
0.5
cytb-5.1 Cytochrome b5
heme-binding domain-containing protein		 Caenorhabditis elegans
TI:6239 None
 
CYB5_DROME
FlyBase»
2.1
Cyt-b5 Cytochrome b5 (CYTB5) Drosophila melanogaster
TI:7227 None
 
CYB5_HUMAN
Ensembl»
2.2
CYB5A Cytochrome b5 (Microsomal cytochrome
b5 type A) (MCB5)		 Homo sapiens
TI:9606 None
 
Q75JN6_DICDI
dictyBase»
2.0
cyb5A Cytochrome b5 A Dictyostelium discoideum
TI:44689 None
 
Q86L22_DICDI
dictyBase»
2.0
cyb5B Cytochrome b5 B Dictyostelium discoideum
TI:44689 None
 
Q54XT7_DICDI
dictyBase»
0.5
cyb5C Cytochrome b5 C Dictyostelium discoideum
TI:44689 None
 
Q55C71_DICDI
dictyBase»
0.5
DDB_G0270752 Cytochrome b5 domain-containing protein Dictyostelium discoideum
TI:44689 None
 
CYB5A_ARATH
TAIR»
0.0
CB5-A Cytochrome b5 isoform A (AtCb5-A)
(Cytochrome b5 isoform D) (AtCb5-D)		 Arabidopsis thaliana
TI:3702 None
 
CYB5B_ARATH
TAIR»
1.6
CYTB5-B Cytochrome b5 isoform B (AtCb5-B) (Cytochrome b5
isoform 2) (Cytochrome b5 isoform E) (AtCb5-E)		 Arabidopsis thaliana
TI:3702 None
 
CYB5E_ARATH
TAIR»
0.0
CYTB5-E Cytochrome b5 isoform E (AtCb5-E) (Cytochrome b5
isoform 1) (Cytochrome b5 isoform A) (AtCb5-A)		 Arabidopsis thaliana
TI:3702 None
 
A0A8V0XSW8_CHICK
Ensembl»
0.0
CYB5B Cytochrome b5 type B Gallus gallus
TI:9031 None
   
Q6NY41_DANRE
ZFIN»
2.1
zgc:76963 Cytochrome b5 type B Danio rerio
TI:7955 None
 
CYB5B_HUMAN
Ensembl»
3.9
CYB5B Cytochrome b5 type B (Cytochrome
b5 outer mitochondrial membrane isoform)		 Homo sapiens
TI:9606 None
 
CYB5B_MOUSE
Ensembl»
0.0
Cyb5b Cytochrome b5 type B (Cytochrome
b5 outer mitochondrial membrane isoform)		 Mus musculus
TI:10090 None
 
CYB5B_RAT
RGD»
3.7
Cyb5b Cytochrome b5 type B (Cytochrome
b5 outer mitochondrial membrane isoform)		 Rattus norvegicus
TI:10116 None
 
Q0P3V8_DANRE
ZFIN»
1.0
zgc:153777 Fatty acid 2-hydroxylase
(Zgc:153777) (Zgc:153777 protein)		 Danio rerio
TI:7955 None
 
Q9VJC0_DROME
FlyBase»
1.0
Dmel\CG6870 GEO08203p1 (RH01575p) (RH01692p) (Uncharacterized protein,
isoform A) (Uncharacterized protein, isoform B)		 Drosophila melanogaster
TI:7227 None
 
Q9VUZ3_DROME
FlyBase»
0.5
Dmel\CG5157 GEO11555p1 (IP06242p) Drosophila melanogaster
TI:7227 None
 
CYB51_SCHPO
PomBase»
1.5
SPBC29A10.16c Probable cytochrome b5 1 Schizosaccharomyces pombe
TI:4896 None
 
CYB52_SCHPO
PomBase»
1.5
oca8 Probable cytochrome b5 2 Schizosaccharomyces pombe
TI:4896 None
 
Q8IRR0_DROME
FlyBase»
1.0
Dmel\CG3566 Uncharacterized protein, isoform B Drosophila melanogaster
TI:7227 None