Collated Gene Ontology terms

Biological process: methyltransferase activity(2024) RNA methyltransferase activity(2024) RNA binding(2014, 2024) metal ion binding(2024) S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity(2022, 2023, 2024) DNA binding(2024) nucleic acid binding(2024) C-methyltransferase activity(2022, 2024) rRNA (uridine-C5-)-methyltransferase activity(2022, 2024) transcription cis-regulatory region binding(2020, 2024)
S-adenosylmethionine-dependent methyltransferase activity2024 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water2024 oxidoreductase activity2024 mRNA binding2006 acyl-CoA desaturase activity2024

Molecular function: methylation2024 RNA processing2024 rRNA methylation2024 RNA modification2024 tRNA processing2024 rRNA processing2024 mRNA processing2024 lipid metabolic process2024 fatty acid metabolic process2024 fatty acid biosynthetic process2024
7-methylguanosine cap hypermethylation2024

Cellular component: mitochondrion2009, 2022, 2024 mitochondrial matrix2023, 2024 cytosol2022, 2024 membrane2024 cytoplasm2024 nucleus2017

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 2/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 4/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 36/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
TRM2A_MOUSE
Ensembl»
1.0
Trmt2a tRNA (uracil-5-)-methyltransferase homolog A (EC 2.1.1.35) (HpaII tiny
fragments locus 9c protein) (mRNA (uracil-5-)-methyltransferase TRMT2A) (EC 2.1.1.-)		 Mus musculus
TI:10090 None
 
TRM2B_HUMAN
Ensembl»
1.6
TRMT2B tRNA (uracil-5-)-methyltransferase homolog B (EC 2.1.1.35) (TRM2
homolog B) (rRNA (uracil-5-)-methyltransferase TRMT2B) (EC 2.1.1.-)		 Homo sapiens
TI:9606 None
 
TRM2A_HUMAN
Ensembl»
2.1
TRMT2A tRNA (uracil-5-)-methyltransferase homolog A (EC
2.1.1.35) (mRNA (uracil-5-)-methyltransferase TRMT2A) (EC 2.1.1.-)		 Homo sapiens
TI:9606 None
 
C3H24_ARATH
TAIR»
0.8
At2g28450 Zinc finger CCCH domain-containing
protein 24 (AtC3H24) (EC 2.1.1.-)		 Arabidopsis thaliana
TI:3702 None
 
TRM2B_MOUSE
Ensembl»
1.6
Trmt2b tRNA (uracil-5-)-methyltransferase homolog B (EC 2.1.1.35) (TRM2
homolog B) (rRNA (uracil-5-)-methyltransferase TRMT2B) (EC 2.1.1.-)		 Mus musculus
TI:10090 None
 
TRM2B_DANRE
ZFIN»
1.0
trmt2b tRNA (uracil-5-)-methyltransferase homolog B (EC 2.1.1.35) (TRM2
homolog B) (rRNA (uracil-5-)-methyltransferase TRMT2B) (EC 2.1.1.-)		 Danio rerio
TI:7955 None
 
Q54C42_DICDI
dictyBase»
0.0
DDB_G0293244 Uncharacterized protein Dictyostelium discoideum
TI:44689 None
 
Q7ZVY1_DANRE
ZFIN»
0.0
fa10b06 tRNA (uracil(54)-C(5))-methyltransferase
(EC 2.1.1.35)		 Danio rerio
TI:7955 None
 
Q9N5L0_CAEEL
WormBase»
0.0
trm-2a tRNA (uracil(54)-C(5))-methyltransferase
(EC 2.1.1.35)		 Caenorhabditis elegans
TI:6239 None
 
Q9VVV7_DROME
FlyBase»
1.0
Dmel\CG3808 tRNA (uracil(54)-C(5))-methyltransferase
(EC 2.1.1.35)		 Drosophila melanogaster
TI:7227 None
 
A0A8I5ZVZ4_RAT
RGD»
0.0
ENSRNOG00000063806 Uncharacterized protein Rattus norvegicus
TI:10116 None 		     
A0A8I6AAN1_RAT
RGD»
1.0
Trmt2a tRNA (uracil(54)-C(5))-methyltransferase
(EC 2.1.1.35)		 Rattus norvegicus
TI:10116 None
   
A0A8V0YWE0_CHICK
Ensembl»
0.0
TRMT2B tRNA (uracil(54)-C(5))-methyltransferase
(EC 2.1.1.35)		 Gallus gallus
TI:9031 None
   
A0A8V0ZM48_CHICK
Ensembl»
0.0
TRMT2A tRNA (uracil(54)-C(5))-methyltransferase
(EC 2.1.1.35)		 Gallus gallus
TI:9031 None