Collated Gene Ontology terms

Biological process: RNA binding(2006, 2019, 2020, 2024) mRNA 3'-UTR binding(2014)

Molecular function: mRNA 3'-end processing by stem-loop binding and cleavage2009, 2010, 2020, 2024 mRNA processing2023, 2024 RNA 3'-end processing2024 ncRNA-mediated post-transcriptional gene silencing2006, 2024 secondary metabolite biosynthetic process2024 co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway2023, 2024 termination of RNA polymerase II transcription, poly(A)-coupled2018 mRNA trans splicing, via spliceosome2016 mRNA 3'-end processing2015 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021
endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021

Cellular component: mRNA cleavage and polyadenylation specificity factor complex2003, 2004, 2006, 2010, 2012, 2014, 2015, 2016, 2017, 2018, 2020, 2024 nucleus2007, 2009, 2017, 2018, 2024 postsynapse2024 glutamatergic synapse2024 cytoplasm2014, 2024 nucleoplasm2017, 2022 plasmodesma2021 membrane2014

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 3/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 34/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
CPSF2_HUMAN
Ensembl»
1.8
CPSF2 Cleavage and polyadenylation specificity factor subunit 2 (Cleavage and
polyadenylation specificity factor 100 kDa subunit) (CPSF 100 kDa subunit)		 Homo sapiens
TI:9606 None
 
CFT2_YEAST
SGD»
2.7
CFT2 Cleavage factor two protein 2 (105
kDa protein associated with polyadenylation factor I)		 Saccharomyces cerevisiae
TI:4932 None
 
CPSF2_ARATH
TAIR»
0.8
CPSF100 Cleavage and polyadenylation specificity factor subunit 2 (Cleavage and polyadenylation specificity factor 100 kDa
subunit) (AtCPSF100) (CPSF 100 kDa subunit) (Protein EMBRYO DEFECTIVE 1265) (Protein ENHANCED SILENCING PHENOTYPE 5)		 Arabidopsis thaliana
TI:3702 None
 
CPSF2_DROME
FlyBase»
2.6
Cpsf100 Probable cleavage and polyadenylation specificity factor subunit 2 (Cleavage and
polyadenylation specificity factor 100 kDa subunit) (CPSF 100 kDa subunit)		 Drosophila melanogaster
TI:7227 None
 
CPSF2_MOUSE
Ensembl»
0.5
Cpsf2 Cleavage and polyadenylation specificity factor subunit 2 (Cleavage and
polyadenylation specificity factor 100 kDa subunit) (CPSF 100 kDa subunit)		 Mus musculus
TI:10090 None
 
D3Z9E6_RAT
RGD»
1.5
Cpsf2 Cleavage and polyadenylation specificity factor subunit 2
(Cleavage and polyadenylation specificity factor 100 kDa subunit)		 Rattus norvegicus
TI:10116 None
   
CPSF2_CAEEL
WormBase»
2.0
cpsf-2 Probable cleavage and polyadenylation specificity factor subunit 2 (Cleavage and
polyadenylation specificity factor 100 kDa subunit) (CPSF 100 kDa subunit)		 Caenorhabditis elegans
TI:6239 None
 
CPSF2_DICDI
dictyBase»
1.5
cpsf2 Cleavage and polyadenylation specificity factor subunit 2 (Cleavage and
polyadenylation specificity factor 100 kDa subunit) (CPSF 100 kDa subunit)		 Dictyostelium discoideum
TI:44689 None
 
F1NMN0_CHICK
Ensembl»
1.0
CPSF2 Cleavage and polyadenylation specificity factor subunit 2
(Cleavage and polyadenylation specificity factor 100 kDa subunit)		 Gallus gallus
TI:9031 None
   
CFT2_SCHPO
PomBase»
1.5
cft2 Cleavage factor two protein 2 Schizosaccharomyces pombe
TI:4896 None
 
F1QVV4_DANRE
ZFIN»
1.0
zgc:92484 Cleavage and polyadenylation specificity factor subunit 2
(Cleavage and polyadenylation specificity factor 100 kDa subunit)		 Danio rerio
TI:7955 None