Collated Gene Ontology terms

Biological process: 2-(3-amino-3-carboxypropyl)histidine synthase activity(2021, 2022, 2024) metal ion binding(2024) iron-sulfur cluster binding(2024) transferase activity(2024) 4 iron, 4 sulfur cluster binding(2022, 2024) ligase activity(2024) diphthine-ammonia ligase activity(2024)

Molecular function: peptidyl-diphthamide biosynthetic process from peptidyl-histidine2013, 2014, 2022, 2023, 2024 fibroblast proliferation2004, 2024 regulation of cytoplasmic translation2009 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021 response to retinoic acid2008 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021

Cellular component: cytoplasm2008, 2014, 2017, 2018, 2024 nucleus2008, 2009, 2024 nucleoplasm2023, 2024 cell junction2023, 2024 cytosol2009, 2014, 2023 membrane2024 ciliary plasm2017

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 3/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 37/39 
Archea: 6/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
A0A8V0ZCB3_CHICK
Ensembl»
0.0
DPH2 2-(3-amino-3-carboxypropyl)histidine synthase
subunit 2		 Gallus gallus
TI:9031 None
   
Q9M1A5_ARATH
TAIR»
0.0
T16L24.180 2-(3-amino-3-carboxypropyl)histidine synthase
subunit 2		 Arabidopsis thaliana
TI:3702 None
 
Q9VFE9_DROME
FlyBase»
1.5
Dph2 2-(3-amino-3-carboxypropyl)histidine synthase
subunit 2		 Drosophila melanogaster
TI:7227 None
 
A0A8J8XLI9_RAT
RGD»
2.5
Dph1 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 (EC 2.5.1.108) (Diphthamide biosynthesis protein
1) (Diphtheria toxin resistance protein 1) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1)		 Rattus norvegicus
TI:10116 None
   
A0A8V1AM15_CHICK
Ensembl»
0.0
DPH1 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 (EC 2.5.1.108) (Diphthamide biosynthesis protein
1) (Diphtheria toxin resistance protein 1) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1)		 Gallus gallus
TI:9031 None
   
DPH1_CAEEL
WormBase»
2.0
dph-1 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 (EC 2.5.1.108) (Diphthamide biosynthesis protein
1) (Diphtheria toxin resistance protein 1) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1)		 Caenorhabditis elegans
TI:6239 None
 
DPH1_CHICK
VEuPathDB»
2.0
DPH1 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 (EC 2.5.1.108) (Diphthamide biosynthesis protein
1) (Diphtheria toxin resistance protein 1) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1)		 Gallus gallus
TI:9031 None
 
DPH1_DANRE
ZFIN»
2.0
dph1 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 (EC 2.5.1.108) (Diphthamide biosynthesis protein
1) (Diphtheria toxin resistance protein 1) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1)		 Danio rerio
TI:7955 None
 
DPH1_DICDI
dictyBase»
2.0
dph1 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 (EC 2.5.1.108) (Diphthamide biosynthesis protein
1) (Diphtheria toxin resistance protein 1) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1)		 Dictyostelium discoideum
TI:44689 None
 
DPH1_SCHPO
PomBase»
3.0
dph1 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 (EC 2.5.1.108) (Diphthamide biosynthesis protein
1) (Diphtheria toxin resistance protein 1) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1)		 Schizosaccharomyces pombe
TI:4896 None
 
DPH1_YEAST
SGD»
4.5
DPH1 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 (EC 2.5.1.108) (Diphthamide biosynthesis protein
1) (Diphtheria toxin resistance protein 1) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1)		 Saccharomyces cerevisiae
TI:4932 None
 
Q8RWW3_ARATH
TAIR»
0.0
MTG10.5 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 (EC 2.5.1.108) (Diphthamide biosynthesis protein
1) (Diphtheria toxin resistance protein 1) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1)		 Arabidopsis thaliana
TI:3702 None
 
Q9VTM2_DROME
FlyBase»
1.5
Dph1 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 (EC 2.5.1.108) (Diphthamide biosynthesis protein
1) (Diphtheria toxin resistance protein 1) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1)		 Drosophila melanogaster
TI:7227 None
 
DPH1_HUMAN
Ensembl»
2.0
DPH1 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 (EC 2.5.1.108) (Diphthamide biosynthesis protein 1) (Diphtheria
toxin resistance protein 1) (Ovarian cancer-associated gene 1 protein) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1)		 Homo sapiens
TI:9606 None
 
DPH1_MOUSE
Ensembl»
3.9
Dph1 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 (EC 2.5.1.108) (Diphthamide biosynthesis protein 1) (Diphtheria toxin
resistance protein 1) (Ovarian cancer-associated gene 1 protein homolog) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1)		 Mus musculus
TI:10090 None
 
DPH2_CAEEL
WormBase»
2.0
dph-2 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 (Diphthamide biosynthesis protein 2)
(Diphtheria toxin resistance protein 2) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2)		 Caenorhabditis elegans
TI:6239 None
 
DPH2_CHICK
CTD»
2.0
DPH2 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 (Diphthamide biosynthesis protein 2)
(Diphtheria toxin resistance protein 2) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2)		 Gallus gallus
TI:9031 None
 
DPH2_DANRE
ZFIN»
2.0
dph2 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 (Diphthamide biosynthesis protein 2)
(Diphtheria toxin resistance protein 2) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2)		 Danio rerio
TI:7955 None
 
DPH2_DICDI
dictyBase»
2.0
dph2 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 (Diphthamide biosynthesis protein 2)
(Diphtheria toxin resistance protein 2) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2)		 Dictyostelium discoideum
TI:44689 None
 
DPH2_HUMAN
Ensembl»
4.5
DPH2 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 (Diphthamide biosynthesis protein 2)
(Diphtheria toxin resistance protein 2) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2)		 Homo sapiens
TI:9606 None
 
DPH2_MOUSE
Ensembl»
1.5
Dph2 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 (Diphthamide biosynthesis protein 2)
(Diphtheria toxin resistance protein 2) (MmDph2) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase DPH2)		 Mus musculus
TI:10090 None
 
DPH2_RAT
RGD»
3.0
Dph2 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 (Diphthamide biosynthesis protein 2)
(Diphtheria toxin resistance protein 2) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2)		 Rattus norvegicus
TI:10116 None
 
DPH2_SCHPO
PomBase»
3.0
dph2 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 (Diphthamide biosynthesis protein 2)
(Diphtheria toxin resistance protein 2) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2)		 Schizosaccharomyces pombe
TI:4896 None
 
DPH2_YEAST
SGD»
4.5
DPH2 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 (Diphthamide biosynthesis protein 2)
(Diphtheria toxin resistance protein 2) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2)		 Saccharomyces cerevisiae
TI:4932 None