Collated Gene Ontology terms

Biological process: oxidoreductase activity(2022, 2024) NAD+ binding(2009, 2024) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(2024) L-gulonate 3-dehydrogenase activity(2009, 2018, 2021, 2022, 2024) enoyl-CoA hydratase activity(2024) 3-hydroxybutyryl-CoA dehydrogenase activity(2012, 2022, 2024) protein homodimerization activity(2009, 2024) 3-hydroxyacyl-CoA dehydrogenase activity(2011, 2024) lyase activity(2024) carnitine 3-dehydrogenase activity(2024)
NAD binding2024 phosphogluconate dehydrogenase (decarboxylating) activity2024 metal ion binding2024 isomerase activity2024 delta(3)-delta(2)-enoyl-CoA isomerase activity2024 3-hydroxybutyryl-CoA epimerase activity2024

Molecular function: fatty acid metabolic process2024 catabolic process2024 fatty acid beta-oxidation2012, 2022, 2024 glucuronate catabolic process to xylulose 5-phosphate2022, 2024 butyrate metabolic process2024 lipid catabolic process2024 phenylacetate catabolic process2012, 2024 carnitine metabolic process2024 sporulation resulting in formation of a cellular spore2024 response to host immune response2010
fatty acid elongation2012 carnitine catabolic process2019

Cellular component: cytosol2009, 2010, 2015, 2022, 2024 cytoplasm2024 membrane2024 plasma membrane2010 peroxisome2021 peptidoglycan-based cell wall2012 extracellular exosome2014

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 0/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 9/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 35/39 
Archea: 3/8 
Bacteria: 15/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
Q9LDF5_ARATH
TAIR»
0.0
At3g15290 3-hydroxyacyl-CoA dehydrogenase family protein (3-hydroxybutyryl-CoA
dehydrogenase-like protein) (Putative 3-hydroxybutyryl-CoA dehydrogenase)		 Arabidopsis thaliana
TI:3702 None
 
PAAH_ECOLI
EnsemblBacteria»
3.4
paaH 3-hydroxyadipyl-CoA dehydrogenase (EC 1.1.1.-) Escherichia coli
TI:562 None
 
Q54VB8_DICDI
dictyBase»
0.5
DDB_G0280465 3-hydroxybutyryl-CoA dehydrogenase Dictyostelium discoideum
TI:44689 None
 
Q5U1B0_DROME
FlyBase»
1.5
Had2 Beta hydroxy acid dehydrogenase
2 (EC 1.1.1.35) (RE67096p)		 Drosophila melanogaster
TI:7227 None
 
Q9VXI1_DROME
FlyBase»
2.6
Had1 Beta hydroxy acid dehydrogenase 1, isoform A (Beta hydroxy
acid dehydrogenase 1, isoform B (EC 1.1.1.35, EC 1.1.1.45)) (RH68464p)		 Drosophila melanogaster
TI:7227 None
 
A0A8V0XPP8_CHICK
Ensembl»
0.0
CRYL1 Crystallin lambda 1 Gallus gallus
TI:9031 None
   
Q0V973_DANRE
ZFIN»
0.5
im:6895749 Crystallin, lambda 1
(Lambda-crystallin homolog (EC 1.1.1.45))		 Danio rerio
TI:7955 None
 
C0VXV5_CAEEL
WormBase»
0.5
CELE_Y71F9B.9 Y71F9B.9 Lambda-crystallin homolog Caenorhabditis elegans
TI:6239 None
 
CRYL1_HUMAN
Ensembl»
2.9
CRYL1 Lambda-crystallin homolog (EC
1.1.1.45) (L-gulonate 3-dehydrogenase) (Gul3DH)		 Homo sapiens
TI:9606 None
 
CRYL1_MOUSE
Ensembl»
2.3
Cryl1 Lambda-crystallin homolog (EC
1.1.1.45) (L-gulonate 3-dehydrogenase) (Gul3DH)		 Mus musculus
TI:10090 None
 
CRYL1_RAT
RGD»
3.5
Cryl1 Lambda-crystallin homolog (EC
1.1.1.45) (L-gulonate 3-dehydrogenase) (Gul3DH)		 Rattus norvegicus
TI:10116 None