Biological process: metal ion binding⁽²⁰²⁴⁾ hydrolase activity⁽²⁰²⁴⁾ cargo adaptor activity^{(2019, 2024)} exonuclease activity⁽²⁰²⁴⁾ pyridoxal phosphate binding⁽²⁰²⁴⁾ phosphoric diester hydrolase activity⁽²⁰¹⁷⁾ molybdenum ion binding⁽²⁰²⁴⁾ manganese ion binding⁽²⁰¹⁷⁾ identical protein binding⁽²⁰¹⁷⁾ catalytic activity⁽²⁰²⁴⁾
± 1 L-phosphoserine phosphatase activity²⁰²⁴

Molecular function: retrograde transport, endosome to Golgi^{2006, 2014, 2015, 2016, 2017, 2018, 2024} protein transport^{2014, 2024} intracellular protein transport^{2004, 2020, 2024} endocytic recycling^{2018, 2019, 2024} vacuolar transport^{2013, 2024} regulation of auxin polar transport^{2022, 2024} receptor recycling^{2013, 2024} protein targeting to vacuole^{2008, 2024} regulation of synaptic vesicle endocytosis²⁰²⁴ regulation of autophagy²⁰¹⁶
± 6 Golgi to vacuole transport^{2001, 2021} viral entry into host cell²⁰²⁰ vesicle-mediated transport²⁰¹⁴ proteasome-mediated ubiquitin-dependent protein catabolic process²⁰²¹ exocytosis²⁰²¹ auxin-activated signaling pathway²⁰²⁴

Cellular component: retromer complex^{2004, 2006, 2013, 2014, 2018, 2019, 2022, 2023, 2024} endosome^{2006, 2010, 2014, 2016, 2020, 2024} cytosol^{2009, 2013, 2014, 2017, 2019, 2023, 2024} endosome membrane²⁰²⁴ membrane^{2006, 2014, 2024} retromer, cargo-selective complex^{2013, 2014, 2015, 2016, 2024} intracellular membrane-bounded organelle^{2012, 2023, 2024} cytoplasm^{2014, 2018, 2024} multivesicular body^{2006, 2024} late endosome²⁰²⁴
± 12 early endosome²⁰²⁴ nucleus^{2009, 2024} neuromuscular junction²⁰²⁴ late endosome membrane^{2014, 2024} protein-containing complex²⁰¹⁹ phagolysosome²⁰¹⁷ phagocytic vesicle²⁰⁰⁹ nuclear lumen²⁰¹⁸ endomembrane system²⁰¹⁸ early phagosome²⁰¹⁷ ciliary plasm²⁰¹⁸ Golgi apparatus²⁰²⁴