Standard knownness: 4.5; Custom knownness: None; Num. species: 74; Orthology database: Panther19.0; Protein members: 118
Molecular function: proteolysis involved in protein catabolic process2023, 2024 ubiquitin-dependent protein catabolic process2023, 2024 protein ubiquitination2010, 2024 protein maturation2023, 2024 protein polyubiquitination2023, 2024 response to virus2024 regulation of cell cycle2024 protein catabolic process2010 positive regulation of ubiquitin-dependent protein catabolic process2019 RNA processing2024
Cellular component: cytoplasm2017, 2023, 2024 ubiquitin ligase complex2021, 2024 cytosol2016, 2023, 2024 nuclear membrane2023, 2024 membrane2024 extracellular region2024 sperm flagellum2021
Chordates: | 22/21 | |
Echinoderms: | 0/0 | |
Hemichordates: | 1/1 | |
Annelids: | 1/1 | |
Molluscs: | 0/0 | |
Bryozoans: | 0/0 | |
Platyhelminthes: | 0/0 | |
Rotifers: | 0/0 | |
Nematodes: | 3/3 | |
Arthropods: | 5/5 | |
Tardigrades: | 0/0 | |
Placozoa: | 1/1 | |
Cnidaria: | 1/1 | |
Porifera: | 0/0 | |
Choanoflagellates+: | 2/1 | |
Dikarya: | 0/14 | |
Fungi (other): | 0/1 | |
Protozoa: | 3/3 | |
Excavates: | 1/4 | |
Harosa: | 1/4 | |
Hacrobia: | 0/0 | |
Plants: | 33/39 | |
Archea: | 0/8 | |
Bacteria: | 0/35 |
Click here to switch to the previous version of the database.
UniProt ID Organism DB» |
Standard knownness | clustom knownness | Gene name | Description | Species [Key only] | GO terms | Seq. links | Protein domain links | |||||
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W1NGK2_AMBTC EnsemblPlants» |
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AMTR_s00010p00240720 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Amborella trichopoda TI:13333 None |
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G1KGZ0_ANOCA Ensembl» |
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RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Anolis carolinensis TI:28377 None |
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H9GBU2_ANOCA Ensembl» |
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RSPRY1 | Ring finger and SPRY domain containing 1 |
Anolis carolinensis TI:28377 None |
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A0A1S4GXE5_ANOGA EnsemblMetazoa» |
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RING finger and SPRY domain-containing protein 1 |
Anopheles gambiae TI:7165 None |
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A0A1S4H0N0_ANOGA EnsemblMetazoa» |
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RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Anopheles gambiae TI:7165 None |
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RKP_ARATH TAIR» |
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RKP | E3 ubiquitin-protein ligase RKP (AtKPC1) (EC 2.3.2.27) (Protein RELATED TO KPC1) (RING-type E3 ubiquitin transferase RKP) |
Arabidopsis thaliana TI:3702 None |
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F4NRW3_BATDJ EnsemblBacteria» |
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BATDEDRAFT_84495 | B30.2/SPRY domain-containing protein |
Batrachochytrium dendrobatidis TI:109871 None |
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F4PBZ8_BATDJ EnsemblBacteria» |
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BATDEDRAFT_27890 | B30.2/SPRY domain-containing protein |
Batrachochytrium dendrobatidis TI:109871 None |
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A4IFG8_BOVIN Ensembl» |
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RSPRY1 | RSPRY1 protein (Ring finger and SPRY domain containing 1) |
Bos taurus TI:9913 None |
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E1BL26_BOVIN Ensembl» |
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RNF123 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Bos taurus TI:9913 None |
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A0A9J7LBB6_BRAFL CTD» |
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LOC118417970 | RING finger and SPRY domain-containing protein 1-like |
Branchiostoma floridae TI:7739 None |
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A0A9J7MP13_BRAFL CTD» |
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LOC118414406 | Uncharacterized protein LOC118414406 |
Branchiostoma floridae TI:7739 None |
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A0A078FLB5_BRANA EnsemblPlants» |
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BnaA09g42890D | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Brassica napus TI:3708 None |
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M4ER02_BRACM EnsemblPlants» |
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RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Brassica campestris TI:3711 None |
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A8Y1R6_CAEBR WormBase» |
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CBG22191 CBG_22191 | Protein CBG22191 |
Caenorhabditis briggsae TI:6238 None |
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P90839_CAEEL WormBase» |
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CELE_F16A11.1 F16A11.1 | RING finger and SPRY domain-containing protein 1 |
Caenorhabditis elegans TI:6239 None |
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A0A8I3MQ14_CANLF Ensembl» |
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RSPRY1 | Ring finger and SPRY domain containing 1 |
Canis lupus TI:9612 None |
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A0A8I3PU69_CANLF Ensembl» |
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RNF123 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Canis lupus TI:9612 None |
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A0A1U8EU57_CAPAN EnsemblPlants» |
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T459_30112 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Capsicum annuum TI:4072 None |
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A0A2K3D3Y4_CHLRE EnsemblPlants» |
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CHLRE_12g519150v5 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Chlamydomonas reinhardtii TI:3055 None |
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F7AYQ0_CIOIN Ensembl» |
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Uncharacterized protein |
Ciona intestinalis TI:7719 None |
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F7B5D3_CIOIN Ensembl» |
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RING-type domain-containing protein |
Ciona intestinalis TI:7719 None |
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Q1RPV0_CIOIN Ensembl» |
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Ci-ZF(RING)-26 | Zinc finger protein |
Ciona intestinalis TI:7719 None |
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A0A067F9Q1_CITSI Ensembl» |
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CISIN_1g000809mg | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Citrus sinensis TI:2711 None |
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A0A0A0KL07_CUCSA EnsemblPlants» |
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Csa_6G487620 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Cucumis sativus TI:3659 None |
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A0A8M3AXY4_DANRE CTD» |
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rnf123 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Danio rerio TI:7955 None |
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A4IG82_DANRE ZFIN» |
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si:ch211-257c9.1 | RING finger and SPRY domain-containing protein 1 precursor (Si:ch211-257c9.1) |
Danio rerio TI:7955 None |
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E9HG27_DAPPU EnsemblMetazoa» |
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DAPPUDRAFT_62402 | RING finger and SPRY domain-containing protein 1 |
Daphnia pulex TI:6669 None |
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F0ZXX5_DICPU EnsemblProtists» |
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DICPUDRAFT_95562 | RING-type domain-containing protein |
Dictyostelium purpureum TI:5786 None |
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Q54N05_DICDI dictyBase» |
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DDB_G0285581 | RING-type domain-containing protein |
Dictyostelium discoideum TI:44689 None |
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Q9VFC4_DROME FlyBase» |
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Kpc1 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Drosophila melanogaster TI:7227 None |
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C4M6N2_ENTH1 EnsemblProtists» |
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EHI_161890 | SPRY domain protein |
Entamoeba histolytica TI:5759 None |
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A0A3Q2H5P8_HORSE Ensembl» |
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RSPRY1 | Ring finger and SPRY domain containing 1 |
Equus caballus TI:9796 None |
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F6TXP6_HORSE Ensembl» |
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RNF123 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Equus caballus TI:9796 None |
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A0A022QX29_ERYGU EnsemblFungi» |
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MIMGU_mgv1a000312mg | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Erythranthe guttata TI:4155 None |
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A0A2I2UHL4_FELCA Ensembl» |
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RNF123 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Felis catus TI:9685 None |
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M3VZF0_FELCA Ensembl» |
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RSPRY1 | Ring finger and SPRY domain containing 1 |
Felis catus TI:9685 None |
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A0A8V0ZNT4_CHICK Ensembl» |
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RSPRY1 | Ring finger and SPRY domain containing 1 |
Gallus gallus TI:9031 None |
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A0A8V1A7T1_CHICK Ensembl» |
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RNF123 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Gallus gallus TI:9031 None |
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I1KBB2_SOYBN EnsemblPlants» |
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100792381 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Glycine max TI:3847 None |
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K7KLL7_SOYBN EnsemblPlants» |
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100800617 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Glycine max TI:3847 None |
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G3S6F3_GORGO Ensembl» |
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RNF123 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Gorilla gorilla TI:9593 None |
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G3SG28_GORGO Ensembl» |
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RSPRY1 | Ring finger and SPRY domain containing 1 |
Gorilla gorilla TI:9593 None |
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A0A1U8K8D5_GOSHI Ensembl» |
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LOC107914376 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Gossypium hirsutum TI:3635 None |
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A0A251SJM2_HELAN EnsemblPlants» |
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RKP | Putative related to KPC1 (Transcription factor C2H2 family) |
Helianthus annuus TI:4232 None |
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A0A251TJ21_HELAN EnsemblPlants» |
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HannXRQ_Chr10g0295251 HanXRQr2_Chr15g0703111 | Putative B30.2/SPRY domain-containing protein (Transcription factor C2H2 family) |
Helianthus annuus TI:4232 None |
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T1G854_HELRO EnsemblMetazoa» |
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20217251 | RING-type domain-containing protein |
Helobdella robusta TI:6412 None |
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RN123_HUMAN Ensembl» |
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RNF123 | E3 ubiquitin-protein ligase RNF123 (EC 2.3.2.27) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123) |
Homo sapiens TI:9606 None |
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RSPRY_HUMAN Ensembl» |
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RSPRY1 | RING finger and SPRY domain-containing protein 1 |
Homo sapiens TI:9606 None |
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B7PGT6_IXOSC EnsemblMetazoa» |
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IscW_ISCW018307 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Ixodes scapularis TI:6945 None |
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B7PVG8_IXOSC EnsemblMetazoa» |
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IscW_ISCW007255 | RING finger and SPRY domain-containing protein, putative (RING finger and SPRY domain-containing protein, putative (Fragment)) |
Ixodes scapularis TI:6945 None |
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A0A2I4H1U3_JUGRE EnsemblPlants» |
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LOC109012772 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Juglans regia TI:51240 None |
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A0A1Y1IQ93_KLENI EnsemblPlants» |
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KFL_008260010 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Klebsormidium nitens TI:105231 None |
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W5MLW2_LEPOC Ensembl» |
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Ring finger and SPRY domain containing 1 |
Lepisosteus oculatus TI:7918 None |
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W5N777_LEPOC Ensembl» |
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RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Lepisosteus oculatus TI:7918 None |
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G7ML89_MACMU Ensembl» |
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RNF123 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Macaca mulatta TI:9544 None |
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G7NPT9_MACMU Ensembl» |
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RSPRY1 | RING finger and SPRY domain-containing protein 1 (Ring finger and SPRY domain containing 1) |
Macaca mulatta TI:9544 None |
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A0A2C9UWH6_MANES EnsemblPlants» |
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MANES_12G141800 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Manihot esculenta TI:3983 None |
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A0A2R6WZ90_MARPO EnsemblPlants» |
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MARPO_0047s0138 | B30.2/SPRY domain-containing protein |
Marchantia polymorpha TI:3197 None |
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G7JA93_MEDTR EnsemblPlants» |
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11443494 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Medicago truncatula TI:3880 None |
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A0A5F8HCK9_MONDO Ensembl» |
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B30.2/SPRY domain-containing protein |
Monodelphis domestica TI:13616 None |
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F7F8B9_MONDO Ensembl» |
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RSPRY1 | Ring finger and SPRY domain containing 1 |
Monodelphis domestica TI:13616 None |
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A9UVX3_MONBE EnsemblProtists» |
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MONBRDRAFT_31870 | B30.2/SPRY domain-containing protein |
Monosiga brevicollis TI:81824 None |
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A9V1H7_MONBE EnsemblProtists» |
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MONBRDRAFT_26147 | RING-type domain-containing protein |
Monosiga brevicollis TI:81824 None |
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A9VAX3_MONBE EnsemblProtists» |
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MONBRDRAFT_29379 | RING-type domain-containing protein |
Monosiga brevicollis TI:81824 None |
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RN123_MOUSE Ensembl» |
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Rnf123 | E3 ubiquitin-protein ligase RNF123 (EC 2.3.2.27) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123) |
Mus musculus TI:10090 None |
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RSPRY_MOUSE Ensembl» |
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Rspry1 | RING finger and SPRY domain-containing protein 1 |
Mus musculus TI:10090 None |
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A0A804K7D8_MUSAM EnsemblPlants» |
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GSMUA_350260.1 | (wild Malaysian banana) hypothetical protein |
Musa acuminata TI:4641 None |
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A0A1U8A432_NELNU EnsemblBacteria» |
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LOC104600027 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Nelumbo nucifera TI:4432 None |
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A7RTP5_NEMVE EnsemblMetazoa» |
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NEMVEDRAFT_v1g93222 | Uncharacterized protein |
Nematostella vectensis TI:45351 None |
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A7S130_NEMVE EnsemblMetazoa» |
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NEMVEDRAFT_v1g242102 | B30.2/SPRY domain-containing protein |
Nematostella vectensis TI:45351 None |
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A7SP45_NEMVE EnsemblMetazoa» |
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NEMVEDRAFT_v1g125602 | RING-type E3 ubiquitin transferase |
Nematostella vectensis TI:45351 None |
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A7STL5_NEMVE EnsemblMetazoa» |
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NEMVEDRAFT_v1g217296 | SPRY domain-containing protein |
Nematostella vectensis TI:45351 None |
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A7STM6_NEMVE EnsemblMetazoa» |
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NEMVEDRAFT_v1g217321 | NAD(P)(+)--arginine ADP-ribosyltransferase (EC 2.4.2.31) (Mono(ADP-ribosyl)transferase) |
Nematostella vectensis TI:45351 None |
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A7T227_NEMVE EnsemblMetazoa» |
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NEMVEDRAFT_v1g248568 | RING-type E3 ubiquitin transferase |
Nematostella vectensis TI:45351 None |
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A0A1S3X6K7_TOBAC EnsemblFungi» |
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LOC107761846 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Nicotiana tabacum TI:4097 None |
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A0A1S4C9K0_TOBAC EnsemblFungi» |
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LOC107816575 | E3 ubiquitin-protein ligase RKP-like |
Nicotiana tabacum TI:4097 None |
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F7FG62_ORNAN Ensembl» |
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RSPRY1 | Ring finger and SPRY domain containing 1 |
Ornithorhynchus anatinus TI:9258 None |
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K7EAP2_ORNAN Ensembl» |
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RNF123 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Ornithorhynchus anatinus TI:9258 None |
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A0A0P0X9C1_ORYSJ EnsemblPlants» |
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Os07g0626900 | Os07g0626900 protein |
Oryza sativa TI:4530 None |
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A0A3B3H2X8_ORYLA Ensembl» |
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rnf123 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Oryzias latipes TI:8090 None |
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A0A3B3I1Q0_ORYLA Ensembl» |
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rspry1 | Ring finger and SPRY domain containing 1 |
Oryzias latipes TI:8090 None |
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H2QB64_PANTR Ensembl» |
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RSPRY1 | Ring finger and SPRY domain containing 1 |
Pan troglodytes TI:9598 None |
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|||||
K7AI08_PANTR Ensembl» |
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RNF123 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Pan troglodytes TI:9598 None |
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A0A2K1J3X6_PHYPA EnsemblPlants» |
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PHYPA_022085 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Physcomitrium patens TI:3218 None |
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A0A2K1KZX1_PHYPA EnsemblPlants» |
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PHYPA_002113 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Physcomitrium patens TI:3218 None |
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A0A2K1LAV1_PHYPA EnsemblPlants» |
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PHYPA_001572 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Physcomitrium patens TI:3218 None |
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H3GXJ2_PHYRM EnsemblProtists» |
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Replication stress response regulator SDE2 |
Phytophthora ramorum TI:164328 None |
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A0A2K1ZR59_POPTR EnsemblPlants» |
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POPTR_007G081900 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Populus trichocarpa TI:3694 None |
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A0A2K2ADK6_POPTR EnsemblPlants» |
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POPTR_005G083800 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Populus trichocarpa TI:3694 None |
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A0A2A6BND0_PRIPA EnsemblMetazoa» |
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WBGene00113208 | 3'-phosphate/5'-hydroxy nucleic acid ligase (EC 6.5.1.8) |
Pristionchus pacificus TI:54126 None |
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M5WJC4_PRUPE EnsemblPlants» |
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PRUPE_6G174100 | B30.2/SPRY domain-containing protein |
Prunus persica TI:3760 None |
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A0A0G2K1G4_RAT RGD» |
|
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Rspry1 | Ring finger and SPRY domain containing 1 |
Rattus norvegicus TI:10116 None |
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||||||
RN123_RAT RGD» |
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Rnf123 | E3 ubiquitin-protein ligase RNF123 (EC 2.3.2.27) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123) |
Rattus norvegicus TI:10116 None |
|
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B9SRQ3_RICCO EnsemblBacteria» |
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RCOM_0666070 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Ricinus communis TI:3988 None |
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D8RTJ8_SELML EnsemblPlants» |
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SELMODRAFT_149782 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Selaginella moellendorffii TI:88036 None |
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D8T5L4_SELML EnsemblPlants» |
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SELMODRAFT_161247 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Selaginella moellendorffii TI:88036 None |
|
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K3ZQ34_SETIT EnsemblPlants» |
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101763193 | B30.2/SPRY domain-containing protein |
Setaria italica TI:4555 None |
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A0A3Q7G5Q0_SOLLC EnsemblPlants» |
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RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Solanum lycopersicum TI:4081 None |
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|||||||
M1AZJ1_SOLTU EnsemblPlants» |
|
|
RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Solanum tuberosum TI:4113 None |
|
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|||||||
A0A1B6QFT2_SORBI EnsemblPlants» |
|
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SORBI_3002G383600 | B30.2/SPRY domain-containing protein |
Sorghum bicolor TI:4558 None |
|
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A0A7M7N5B5_STRPU EnsemblMetazoa» |
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RING finger and SPRY domain-containing protein 1 |
Strongylocentrotus purpuratus TI:7668 None |
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A0A7M7NTU7_STRPU EnsemblMetazoa» |
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B30.2/SPRY domain-containing protein |
Strongylocentrotus purpuratus TI:7668 None |
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A0A5G2QSZ2_PIG Ensembl» |
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RNF123 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Sus scrofa TI:9823 None |
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F1RF31_PIG Ensembl» |
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RSPRY1 | Ring finger and SPRY domain containing 1 |
Sus scrofa TI:9823 None |
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A0A061DI86_THECC EnsemblPlants» |
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TCM_001227 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Theobroma cacao TI:3641 None |
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A0A139WM94_TRICA EnsemblMetazoa» |
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AUGUSTUS-3.0.2_32293 | RING finger and SPRY domain-containing protein 1-like Protein |
Tribolium castaneum TI:7070 None |
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B3S373_TRIAD EnsemblMetazoa» |
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TRIADDRAFT_58620 | B30.2/SPRY domain-containing protein |
Trichoplax adhaerens TI:10228 None |
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B3S6N5_TRIAD EnsemblMetazoa» |
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TRIADDRAFT_64223 | B30.2/SPRY domain-containing protein |
Trichoplax adhaerens TI:10228 None |
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Q387L2_TRYB2 VEuPathDB» |
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Tb11.03.0740 | B30.2/SPRY domain-containing protein |
Trypanosoma brucei TI:5691 None |
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F6H4A3_VITVI EnsemblPlants» |
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VIT_07s0031g01490 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Vitis vinifera TI:29760 None |
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A0A1L8GKJ2_XENLA Xenbase» |
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rspry1.L | RING finger and SPRY domain-containing protein 1 |
Xenopus laevis TI:8355 None |
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A0A1L8GP90_XENLA Xenbase» |
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rnf123.L | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Xenopus laevis TI:8355 None |
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A0A8J0QP78_XENTR Xenbase» |
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rnf123 | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Xenopus tropicalis TI:8364 None |
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A0A8J1KJW3_XENLA Xenbase» |
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rnf123.S | RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Xenopus laevis TI:8355 None |
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Q28E18_XENTR Xenbase» |
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rspry1 | Novel protein containing SPRY domain-containing SOCS box protein SSB-3 (RING finger and SPRY domain-containing protein 1) (Ring finger and SPRY domain containing 1) |
Xenopus tropicalis TI:8364 None |
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Q66KG1_XENLA Xenbase» |
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rspry1.S | MGC86306 protein (Ring finger and SPRY domain containing 1 S homeolog) |
Xenopus laevis TI:8355 None |
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A0A804QFA2_MAIZE EnsemblPlants» |
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E3 ubiquitin-protein ligase RKP |
Zea mays TI:4577 None |
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