Collated Gene Ontology terms

Biological process: ubiquitin-protein transferase activity(2017, 2023) metal ion binding(2023) ubiquitin-ubiquitin ligase activity(2023) ubiquitin protein ligase activity(2020, 2023) transferase activity(2023) ligase activity(2023) zinc ion binding(2014) nucleotidyltransferase activity(2023) nucleotide binding(2023) glycosyltransferase activity(2023)
RNA ligase activity2023 RNA binding2023 NAD+-protein-arginine ADP-ribosyltransferase activity2023 GTP binding2023 DNA binding2023

Molecular function: proteolysis involved in protein catabolic process2017, 2023 ubiquitin-dependent protein catabolic process2023 protein ubiquitination2010, 2023 protein maturation2023 protein polyubiquitination2023 response to virus2023 regulation of cell cycle2023 tRNA processing2023 protein catabolic process2010 positive regulation of ubiquitin-dependent protein catabolic process2019
mRNA processing2023 cell cycle2023 RNA splicing2023 RNA processing2023

Cellular component: cytoplasm2017, 2023 ubiquitin ligase complex2021, 2023 cytosol2016, 2023 nuclear membrane2023 membrane2023 extracellular region2023 sperm flagellum2021 nucleus2023 membrane-bounded organelle2023 cilium2023
cellular anatomical entity2023 cell projection2023

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 2/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 1/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 33/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 0 2 4 6 8 10 Knownness

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
W1NGK2_AMBTC
EnsemblPlants»
0.0
AMTR_s00010p00240720 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Amborella trichopoda
TI:13333 None
 
G1KGZ0_ANOCA
Ensembl»
0.0
RING-type E3 ubiquitin transferase (EC 2.3.2.27) Anolis carolinensis
TI:28377 None
   
H9GBU2_ANOCA
Ensembl»
0.0
RSPRY1 Ring finger and SPRY domain containing 1 Anolis carolinensis
TI:28377 None
   
A0A1S4GXE5_ANOGA
EnsemblMetazoa»
0.0
RING finger and SPRY domain-containing protein 1 Anopheles gambiae
TI:7165 None
 
A0A1S4H0N0_ANOGA
EnsemblMetazoa»
0.0
RING-type E3 ubiquitin transferase (EC 2.3.2.27) Anopheles gambiae
TI:7165 None
 
RKP_ARATH
TAIR»
4.2
RKP E3 ubiquitin-protein ligase RKP (AtKPC1) (EC 2.3.2.27) (Protein
RELATED TO KPC1) (RING-type E3 ubiquitin transferase RKP)		 Arabidopsis thaliana
TI:3702 None
 
F4NRW3_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_84495 B30.2/SPRY domain-containing protein Batrachochytrium dendrobatidis
TI:109871 None
 
F4PBZ8_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_27890 B30.2/SPRY domain-containing protein Batrachochytrium dendrobatidis
TI:109871 None
 
A4IFG8_BOVIN
Ensembl»
0.0
RSPRY1 RSPRY1 protein (Ring finger
and SPRY domain containing 1)		 Bos taurus
TI:9913 None
 
E1BL26_BOVIN
Ensembl»
0.0
RNF123 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Bos taurus
TI:9913 None
   
A0A9J7LBB6_BRAFL
CTD»
0.0
LOC118417970 RING finger and
SPRY domain-containing protein 1-like		 Branchiostoma floridae
TI:7739 None
   
A0A9J7MP13_BRAFL
CTD»
0.0
LOC118414406 Uncharacterized protein LOC118414406 Branchiostoma floridae
TI:7739 None
   
A0A078FLB5_BRANA
EnsemblPlants»
0.0
BnaA09g42890D RING-type E3 ubiquitin transferase (EC 2.3.2.27) Brassica napus
TI:3708 None
 
A8Y1R6_CAEBR
WormBase»
0.0
CBG22191 CBG_22191 Protein CBG22191 Caenorhabditis briggsae
TI:6238 None
 
P90839_CAEEL
WormBase»
1.0
CELE_F16A11.1 F16A11.1 RING finger and SPRY domain-containing protein 1 Caenorhabditis elegans
TI:6239 None
 
A0A8I3MQ14_CANLF
Ensembl»
0.0
RSPRY1 Ring finger and SPRY domain containing 1 Canis lupus
TI:9612 None
   
A0A8I3PU69_CANLF
Ensembl»
0.0
RNF123 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Canis lupus
TI:9612 None
   
A0A1U8EU57_CAPAN
EnsemblPlants»
0.0
T459_30112 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Capsicum annuum
TI:4072 None
 
A0A2K3D3Y4_CHLRE
EnsemblPlants»
0.0
CHLRE_12g519150v5 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Chlamydomonas reinhardtii
TI:3055 None
 
F7AYQ0_CIOIN
Ensembl»
0.0
Uncharacterized protein Ciona intestinalis
TI:7719 None
 
F7B5D3_CIOIN
Ensembl»
0.0
RING-type domain-containing protein Ciona intestinalis
TI:7719 None
 
Q1RPV0_CIOIN
Ensembl»
0.0
Ci-ZF(RING)-26 Zinc finger protein Ciona intestinalis
TI:7719 None
 
A0A067F9Q1_CITSI
Ensembl»
0.0
CISIN_1g000809mg RING-type E3 ubiquitin transferase (EC 2.3.2.27) Citrus sinensis
TI:2711 None
 
A0A0A0KL07_CUCSA
EnsemblPlants»
0.0
Csa_6G487620 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Cucumis sativus
TI:3659 None
 
A0A8M3AXY4_DANRE
CTD»
0.0
rnf123 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Danio rerio
TI:7955 None
   
A4IG82_DANRE
ZFIN»
1.0
si:ch211-257c9.1 RING finger and SPRY
domain-containing protein 1 precursor (Si:ch211-257c9.1)		 Danio rerio
TI:7955 None
 
E9HG27_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_62402 RING finger and SPRY domain-containing protein 1 Daphnia pulex
TI:6669 None
 
F0ZXX5_DICPU
EnsemblProtists»
0.0
DICPUDRAFT_95562 RING-type domain-containing protein Dictyostelium purpureum
TI:5786 None
 
Q54N05_DICDI
dictyBase»
1.0
DDB_G0285581 RING-type domain-containing protein Dictyostelium discoideum
TI:44689 None
 
Q9VFC4_DROME
FlyBase»
2.0
Kpc1 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Drosophila melanogaster
TI:7227 None
 
C4M6N2_ENTH1
EnsemblProtists»
0.0
EHI_161890 SPRY domain protein Entamoeba histolytica
TI:5759 None
 
A0A3Q2H5P8_HORSE
Ensembl»
0.0
RSPRY1 Ring finger and SPRY domain containing 1 Equus caballus
TI:9796 None
   
F6TXP6_HORSE
Ensembl»
0.0
RNF123 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Equus caballus
TI:9796 None
   
A0A022QX29_ERYGU
Ensembl»
0.0
MIMGU_mgv1a000312mg RING-type E3 ubiquitin transferase (EC 2.3.2.27) Erythranthe guttata
TI:4155 None
 
A0A059B937_EUCGR
EnsemblPlants»
0.0
EUGRSUZ_H04838 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Eucalyptus grandis
TI:71139 None
 
A0A2I2UHL4_FELCA
Ensembl»
0.0
RNF123 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Felis catus
TI:9685 None
 
A0A5F5XNL3_FELCA
Ensembl»
0.0
RSPRY1 Ring finger and SPRY domain containing 1 Felis catus
TI:9685 None
 
A0A8V0ZNT4_CHICK
Ensembl»
0.0
RSPRY1 Ring finger and SPRY domain containing 1 Gallus gallus
TI:9031 None
   
A0A8V1A7T1_CHICK
Ensembl»
0.0
RNF123 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Gallus gallus
TI:9031 None
   
I1KBB2_SOYBN
EnsemblPlants»
0.0
100792381 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Glycine max
TI:3847 None
 
K7KLL7_SOYBN
EnsemblPlants»
0.0
100800617 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Glycine max
TI:3847 None
 
G3S6F3_GORGO
Ensembl»
0.0
RNF123 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Gorilla gorilla
TI:9593 None
 
G3SG28_GORGO
Ensembl»
0.0
RSPRY1 Ring finger and SPRY domain containing 1 Gorilla gorilla
TI:9593 None
 
A0A1U8K8D5_GOSHI
Ensembl»
0.0
LOC107914376 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Gossypium hirsutum
TI:3635 None
   
A0A251SJM2_HELAN
EnsemblPlants»
0.0
RKP Putative related to KPC1
(Transcription factor C2H2 family)		 Helianthus annuus
TI:4232 None
 
A0A251TJ21_HELAN
EnsemblPlants»
0.0
HannXRQ_Chr10g0295251 HanXRQr2_Chr15g0703111 Putative B30.2/SPRY domain-containing protein
(Transcription factor C2H2 family)		 Helianthus annuus
TI:4232 None
 
T1G854_HELRO
EnsemblMetazoa»
0.0
20217251 RING-type domain-containing protein Helobdella robusta
TI:6412 None
 
RN123_HUMAN
Ensembl»
4.2
RNF123 E3 ubiquitin-protein ligase RNF123 (EC 2.3.2.27) (Kip1
ubiquitination-promoting complex protein 1) (RING finger protein 123)		 Homo sapiens
TI:9606 None
 
RSPRY_HUMAN
Ensembl»
1.0
RSPRY1 RING finger and SPRY domain-containing protein 1 Homo sapiens
TI:9606 None
 
B7PGT6_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW018307 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Ixodes scapularis
TI:6945 None
 
B7PVG8_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW007255 RING finger and SPRY domain-containing protein, putative
(RING finger and SPRY domain-containing protein, putative (Fragment))		 Ixodes scapularis
TI:6945 None
 
A0A2I4H1U3_JUGRE
EnsemblPlants»
0.0
LOC109012772 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Juglans regia
TI:51240 None
 
A0A1Y1IQ93_KLENI
EnsemblPlants»
0.0
KFL_008260010 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Klebsormidium nitens
TI:105231 None
 
W5MLW2_LEPOC
Ensembl»
0.0
Ring finger and SPRY domain containing 1 Lepisosteus oculatus
TI:7918 None
 
W5N777_LEPOC
Ensembl»
0.0
RING-type E3 ubiquitin transferase (EC 2.3.2.27) Lepisosteus oculatus
TI:7918 None
 
G7ML89_MACMU
Ensembl»
0.0
RNF123 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Macaca mulatta
TI:9544 None
 
G7NPT9_MACMU
Ensembl»
0.0
RSPRY1 RING finger and SPRY domain-containing protein 1
(Ring finger and SPRY domain containing 1)		 Macaca mulatta
TI:9544 None
 
A0A2C9UWH6_MANES
EnsemblPlants»
0.0
MANES_12G141800 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Manihot esculenta
TI:3983 None
 
A0A2R6WZ90_MARPO
EnsemblPlants»
0.0
MARPO_0047s0138 B30.2/SPRY domain-containing protein Marchantia polymorpha
TI:3197 None
 
G7JA93_MEDTR
EnsemblPlants»
0.0
11443494 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Medicago truncatula
TI:3880 None
 
A0A5F8HCK9_MONDO
Ensembl»
0.0
B30.2/SPRY domain-containing protein Monodelphis domestica
TI:13616 None
   
F7F8B9_MONDO
Ensembl»
0.0
RSPRY1 Ring finger and SPRY domain containing 1 Monodelphis domestica
TI:13616 None
   
A9UVX3_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_31870 B30.2/SPRY domain-containing protein Monosiga brevicollis
TI:81824 None
 
A9V1H7_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_26147 RING-type domain-containing protein Monosiga brevicollis
TI:81824 None
 
A9VAX3_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_29379 RING-type domain-containing protein Monosiga brevicollis
TI:81824 None
 
RN123_MOUSE
Ensembl»
4.0
Rnf123 E3 ubiquitin-protein ligase RNF123 (EC 2.3.2.27) (Kip1
ubiquitination-promoting complex protein 1) (RING finger protein 123)		 Mus musculus
TI:10090 None
 
RSPRY_MOUSE
Ensembl»
1.0
Rspry1 RING finger and SPRY domain-containing protein 1 Mus musculus
TI:10090 None
 
A0A804K7D8_MUSAM
EnsemblPlants»
0.0
GSMUA_350260.1 (wild Malaysian banana) hypothetical protein Musa acuminata
TI:4641 None
 
A0A1U8A432_NELNU
EnsemblBacteria»
0.0
LOC104600027 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Nelumbo nucifera
TI:4432 None
 
A7RTP5_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g93222 Uncharacterized protein Nematostella vectensis
TI:45351 None
 
A7S130_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g242102 B30.2/SPRY domain-containing protein Nematostella vectensis
TI:45351 None
 
A7SP45_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g125602 RING-type E3 ubiquitin transferase Nematostella vectensis
TI:45351 None
 
A7STL5_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g217296 SPRY domain-containing protein Nematostella vectensis
TI:45351 None
 
A7STM6_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g217321 NAD(P)(+)--arginine ADP-ribosyltransferase
(EC 2.4.2.31) (Mono(ADP-ribosyl)transferase)		 Nematostella vectensis
TI:45351 None
 
A7T227_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g248568 RING-type E3 ubiquitin transferase Nematostella vectensis
TI:45351 None
 
A0A1S3X6K7_TOBAC
EnsemblFungi»
0.0
LOC107761846 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Nicotiana tabacum
TI:4097 None
   
A0A1S4C9K0_TOBAC
EnsemblFungi»
0.0
LOC107816575 E3 ubiquitin-protein ligase RKP-like Nicotiana tabacum
TI:4097 None
   
F7FG62_ORNAN
Ensembl»
0.0
RSPRY1 Ring finger and SPRY domain containing 1 Ornithorhynchus anatinus
TI:9258 None
   
K7EAP2_ORNAN
Ensembl»
0.0
RNF123 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Ornithorhynchus anatinus
TI:9258 None
   
A0A0P0X9C1_ORYSJ
EnsemblPlants»
0.0
Os07g0626900 Os07g0626900 protein Oryza sativa
TI:4530 None
 
A0A3B3H2X8_ORYLA
Ensembl»
0.0
rnf123 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Oryzias latipes
TI:8090 None
   
A0A3B3I1Q0_ORYLA
Ensembl»
0.0
rspry1 Ring finger and SPRY domain containing 1 Oryzias latipes
TI:8090 None
   
H2QB64_PANTR
Ensembl»
0.0
RSPRY1 Ring finger and SPRY domain containing 1 Pan troglodytes
TI:9598 None
 
K7AI08_PANTR
Ensembl»
0.0
RNF123 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Pan troglodytes
TI:9598 None
 
A0A2K1J3X6_PHYPA
EnsemblPlants»
0.0
PHYPA_022085 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Physcomitrium patens
TI:3218 None
 
A0A2K1KZX1_PHYPA
EnsemblPlants»
0.0
PHYPA_002113 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Physcomitrium patens
TI:3218 None
 
A0A2K1LAV1_PHYPA
EnsemblPlants»
0.0
PHYPA_001572 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Physcomitrium patens
TI:3218 None
 
H3GXJ2_PHYRM
EnsemblProtists»
0.0
Replication stress response regulator SDE2 Phytophthora ramorum
TI:164328 None
 
A0A2K1ZR59_POPTR
EnsemblPlants»
0.0
POPTR_007G081900 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Populus trichocarpa
TI:3694 None
 
A0A2K2ADK6_POPTR
EnsemblPlants»
0.0
POPTR_005G083800 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Populus trichocarpa
TI:3694 None
 
A0A2A6BND0_PRIPA
EnsemblMetazoa»
0.0
WBGene00113208 3'-phosphate/5'-hydroxy nucleic acid
ligase (EC 6.5.1.8)		 Pristionchus pacificus
TI:54126 None
 
M5WJC4_PRUPE
EnsemblPlants»
0.0
PRUPE_6G174100 B30.2/SPRY domain-containing protein Prunus persica
TI:3760 None
 
A0A0G2K1G4_RAT
RGD»
1.0
Rspry1 Ring finger and SPRY domain containing 1 Rattus norvegicus
TI:10116 None
   
RN123_RAT
RGD»
4.0
Rnf123 E3 ubiquitin-protein ligase RNF123 (EC 2.3.2.27) (Kip1
ubiquitination-promoting complex protein 1) (RING finger protein 123)		 Rattus norvegicus
TI:10116 None
   
B9SRQ3_RICCO
EnsemblBacteria»
0.0
RCOM_0666070 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Ricinus communis
TI:3988 None
 
D8RTJ8_SELML
EnsemblPlants»
0.0
SELMODRAFT_149782 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Selaginella moellendorffii
TI:88036 None
 
D8T5L4_SELML
EnsemblPlants»
0.0
SELMODRAFT_161247 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Selaginella moellendorffii
TI:88036 None
 
K3ZQ34_SETIT
EnsemblPlants»
0.0
101763193 B30.2/SPRY domain-containing protein Setaria italica
TI:4555 None
 
A0A3Q7G5Q0_SOLLC
EnsemblPlants»
0.0
RING-type E3 ubiquitin transferase (EC 2.3.2.27) Solanum lycopersicum
TI:4081 None
   
M1AZJ1_SOLTU
EnsemblPlants»
0.0
RING-type E3 ubiquitin transferase (EC 2.3.2.27) Solanum tuberosum
TI:4113 None
   
A0A1B6QFT2_SORBI
EnsemblPlants»
0.0
SORBI_3002G383600 B30.2/SPRY domain-containing protein Sorghum bicolor
TI:4558 None
 
A0A7M7N5B5_STRPU
EnsemblMetazoa»
0.0
RING finger and SPRY domain-containing protein 1 Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7NTU7_STRPU
EnsemblMetazoa»
0.0
B30.2/SPRY domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A286ZKD3_PIG
Ensembl»
0.0
RNF123 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Sus scrofa
TI:9823 None
   
F1RF31_PIG
Ensembl»
0.0
RSPRY1 Ring finger and SPRY domain containing 1 Sus scrofa
TI:9823 None
   
A0A061DI86_THECC
EnsemblPlants»
0.0
TCM_001227 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Theobroma cacao
TI:3641 None
 
A0A139WM94_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_32293 RING finger and SPRY
domain-containing protein 1-like Protein		 Tribolium castaneum
TI:7070 None
 
B3S373_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_58620 B30.2/SPRY domain-containing protein Trichoplax adhaerens
TI:10228 None
 
B3S6N5_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_64223 B30.2/SPRY domain-containing protein Trichoplax adhaerens
TI:10228 None
 
Q387L2_TRYB2
VEuPathDB»
0.0
Tb11.03.0740 B30.2/SPRY domain-containing protein Trypanosoma brucei
TI:5691 None
 
F6H4A3_VITVI
EnsemblPlants»
0.0
VIT_07s0031g01490 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Vitis vinifera
TI:29760 None
 
A0A8J0QP78_XENTR
Xenbase»
0.0
rnf123 RING-type E3 ubiquitin transferase (EC 2.3.2.27) Xenopus tropicalis
TI:8364 None
   
Q28E18_XENTR
Xenbase»
0.0
rspry1 Novel protein containing SPRY domain-containing SOCS box protein SSB-3 (RING finger
and SPRY domain-containing protein 1) (Ring finger and SPRY domain containing 1)		 Xenopus tropicalis
TI:8364 None
 
A0A804QFA2_MAIZE
EnsemblPlants»
0.0
E3 ubiquitin-protein ligase RKP Zea mays
TI:4577 None