Collated Gene Ontology terms

Biological process: nucleic acid binding(2025) RNA binding(2006, 2017, 2025) structural constituent of ribosome(2025) ATPase activator activity(2019)

Molecular function: mRNA splicing, via spliceosome2013, 2017, 2020, 2025 mRNA processing2025 RNA splicing2025 translation2025 innate immune response-activating signaling pathway2020 defense response to bacterium2006 defense response2025

Cellular component: spliceosomal complex2013, 2017, 2020, 2025 nucleus2005, 2009, 2017, 2018, 2025 nucleoplasm2015, 2024, 2025 ribosome2025 organelle membrane2025 mitotic spindle2009 cytoplasm2025

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 13/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 1/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 39/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
GPKOW_MOUSE
Ensembl»
2.5
Gpkow G-patch domain and KOW
motifs-containing protein (Protein MOS2 homolog)		 Mus musculus
TI:10090 None
 
GPKOW_HUMAN
Ensembl»
3.5
GPKOW G-patch domain and KOW motifs-containing protein (G-patch
domain-containing protein 5) (Protein MOS2 homolog) (Protein T54)		 Homo sapiens
TI:9606 None
 
G3V8Z3_RAT
RGD»
1.5
Gpkow G-patch domain and KOW motifs-containing protein Rattus norvegicus
TI:10116 None
   
GPKOW_XENLA
Xenbase»
0.0
gpkow G-patch domain and KOW motifs-containing protein Xenopus laevis
TI:8355 None
 
GPKOW_DANRE
ZFIN»
1.5
gpkow G-patch domain and KOW
motifs-containing protein (Protein T54-like)		 Danio rerio
TI:7955 None
 
MOS2_ARATH
TAIR»
2.6
MOS2 Protein MOS2 Arabidopsis thaliana
TI:3702 None
 
SPP2_YEAST
SGD»
2.2
SPP2 Pre-mRNA-splicing factor SPP2 (Spliceosome maturation protein
SPP2) (Suppressor of PRP protein 2)		 Saccharomyces cerevisiae
TI:4932 None
 
A0A3Q2GW21_HORSE
Ensembl»
0.0
GPKOW G-patch domain and KOW motifs-containing protein Equus caballus
TI:9796 None
   
F1RW48_PIG
Ensembl»
0.0
GPKOW G-patch domain and KOW motifs-containing protein Sus scrofa
TI:9823 None
   
G3RCW4_GORGO
Ensembl»
0.0
GPKOW G-patch domain and KOW motifs-containing protein Gorilla gorilla
TI:9593 None
 
H2MHI5_ORYLA
Ensembl»
0.0
GPKOW G-patch domain and KOW motifs-containing protein Oryzias latipes
TI:8090 None
   
H9GND6_ANOCA
Ensembl»
0.0
GPKOW G-patch domain and KOW motifs-containing protein Anolis carolinensis
TI:28377 None
   
K7A3T9_PANTR
Ensembl»
0.0
GPKOW G-patch domain and KOW motifs-containing protein Pan troglodytes
TI:9598 None
 
A0A3Q1LQN8_BOVIN
Ensembl»
0.0
GPKOW G-patch domain and KOW motifs-containing protein Bos taurus
TI:9913 None
   
SPP2_SCHPO
PomBase»
0.5
cwf28 Pre-mRNA-splicing factor cwf28 (Complexed
with cdc5 protein 28)		 Schizosaccharomyces pombe
TI:4896 None
 
A0A8J1LJE0_XENLA
CTD»
0.0
gpkow.L G-patch domain and KOW motifs-containing protein Xenopus laevis
TI:8355 None
   
SPP2_ASPFU
EnsemblFungi»
0.0
spp2 Pre-mRNA-splicing factor spp2 Aspergillus fumigatus
TI:746128 None
 
SPP2_EMENI
EnsemblFungi»
0.0
spp2 Pre-mRNA-splicing factor spp2 Emericella nidulans
TI:162425 None
 
A0A6I8PK07_ORNAN
Ensembl»
0.0
GPKOW G-patch domain and KOW motifs-containing protein Ornithorhynchus anatinus
TI:9258 None
   
A0A8V0XD71_CHICK
Ensembl»
0.5
GPKOW G-patch domain and KOW motifs-containing protein Gallus gallus
TI:9031 None
   
B6JY96_SCHJY
TubercuList»
0.0
cwf28 Pre-mRNA-splicing factor Schizosaccharomyces japonicus
TI:4897 None
 
F7D1Q6_MACMU
Ensembl»
0.0
GPKOW G-patch domain and KOW motifs-containing protein Macaca mulatta
TI:9544 None
   
F7DF73_XENTR
Xenbase»
0.0
gpkow G-patch domain and KOW motifs-containing protein Xenopus tropicalis
TI:8364 None
   
Q6C7F8_YARLI
TubercuList»
0.0
YALI0_E01166g Pre-mRNA-splicing factor Yarrowia lipolytica
TI:4952 None
 
W5NC37_LEPOC
Ensembl»
0.0
G-patch domain and KOW motifs-containing protein Lepisosteus oculatus
TI:7918 None
 
A0A1S3ZYI4_TOBAC
euHCVdb»
0.0
LOC107791790 Protein MOS2 Nicotiana tabacum
TI:4097 None
   
A0A1S4CIE6_TOBAC
euHCVdb»
0.0
LOC107819375 Protein MOS2 Nicotiana tabacum
TI:4097 None
   
A0A1U8K6U8_GOSHI
euHCVdb»
0.0
LOC107914018 Protein MOS2 Gossypium hirsutum
TI:3635 None
   
A0A1U8PBU6_GOSHI
euHCVdb»
0.0
LOC107957631 Protein MOS2 Gossypium hirsutum
TI:3635 None
   
Q9SW24_ARATH
TAIR»
0.5
At4g25020 At4g25020 (D111/G-patch
domain-containing protein)		 Arabidopsis thaliana
TI:3702 None
 
Q9VES0_DROME
FlyBase»
1.0
Gpkow FI23980p1 Drosophila melanogaster
TI:7227 None
 
A0A022RF14_ERYGU
euHCVdb»
0.0
MIMGU_mgv1a006523mg G-patch domain-containing protein Erythranthe guttata
TI:4155 None
 
A0A061ENN8_THECC
neXtProt»
0.0
TCM_021051 MOS2, putative isoform 1 Theobroma cacao
TI:3641 None
 
A0A078GQK3_BRANA
euHCVdb»
0.0
BnaA05g17840D BnaA05g17840D protein Brassica napus
TI:3708 None
 
A0A0A0LCH0_CUCSA
neXtProt»
0.0
Csa_3G636410 G-patch domain-containing protein Cucumis sativus
TI:3659 None
 
A0A0K9PGU6_ZOSMR
euHCVdb»
0.0
ZOSMA_248G00340 G patch domain and KOW motifs-containing protein Zostera marina
TI:29655 None
 
A0A0Q3SC25_BRADI
EnsemblPlants»
0.0
LOC100843324 G-patch domain-containing protein Brachypodium distachyon
TI:15368 None
 
A0A1U8A404_NELNU
euHCVdb»
0.0
LOC104596842 Protein MOS2 Nelumbo nucifera
TI:4432 None
   
A0A1Y1IAJ7_KLENI
neXtProt»
0.0
KFL_003630110 G-patch domain-containing protein Klebsormidium nitens
TI:105231 None
 
A0A251LPJ2_MANES
euHCVdb»
0.0
MANES_03G127100 G-patch domain-containing protein Manihot esculenta
TI:3983 None
 
A0A251PNN7_PRUPE
euHCVdb»
0.0
PRUPE_4G208700 G-patch domain-containing protein Prunus persica
TI:3760 None
 
A0A287PBM8_HORVV
EnsemblPlants»
0.0
LOC123449136 Uncharacterized protein Hordeum vulgare
TI:4513 None
   
A0A2C9W9G1_MANES
euHCVdb»
0.0
MANES_03G127200v8 G-patch domain-containing protein Manihot esculenta
TI:3983 None
 
A0A2G3AGD0_CAPAN
euHCVdb»
0.0
T459_01184 G-patch domain-containing protein Capsicum annuum
TI:4072 None
 
A0A2I4FQ31_JUGRE
neXtProt»
0.0
LOC109001086 Protein MOS2 Juglans regia
TI:51240 None
   
A0A2K1L6F1_PHYPA
EnsemblPlants»
0.0
LOC112291111 G-patch domain-containing protein Physcomitrium patens
TI:3218 None
 
A0A2R6XA80_MARPO
neXtProt»
0.0
MARPO_0027s0115 G-patch domain-containing protein Marchantia polymorpha
TI:3197 None
 
A0A3B6HP00_WHEAT
EnsemblPlants»
0.0
G-patch domain-containing protein Triticum aestivum
TI:4565 None
   
A0A3B6HPF0_WHEAT
EnsemblPlants»
0.0
LOC123085305 G-patch domain-containing protein Triticum aestivum
TI:4565 None
   
A0A3B6IR77_WHEAT
EnsemblPlants»
0.0
LOC123092738 G-patch domain-containing protein Triticum aestivum
TI:4565 None
   
A0A3B6IWC6_WHEAT
EnsemblPlants»
0.0
G-patch domain-containing protein Triticum aestivum
TI:4565 None
   
A0A3B6JK91_WHEAT
EnsemblPlants»
0.0
LOC123098033 G-patch domain-containing protein Triticum aestivum
TI:4565 None
   
A0A3Q7HSM9_SOLLC
EnsemblPlants»
0.0
G-patch domain-containing protein Solanum lycopersicum
TI:4081 None
   
A0A7M7HL31_STRPU
EnsemblMetazoa»
0.0
G-patch domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7MXV5_STRPU
EnsemblMetazoa»
0.0
G-patch domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A7U2EYT4_PHANO
TubercuList»
0.0
JI435_036650 Pre-mRNA-splicing factor Phaeosphaeria nodorum
TI:13684 None
 
A0A804L8B2_MUSAM
EnsemblPlants»
0.0
GSMUA_09190.1 (wild Malaysian banana) hypothetical protein Musa acuminata
TI:4641 None
 
A0A9J7MQU4_BRAFL
neXtProt»
0.0
LOC118415337 G-patch domain and KOW
motifs-containing protein-like isoform X1		 Branchiostoma floridae
TI:7739 None
   
A0A9K3JPZ9_HELAN
euHCVdb»
0.0
HanXRQr2_Chr02g0073691 G-patch domain-containing protein Helianthus annuus
TI:4232 None
 
A0A9R1V7N6_LACSA
neXtProt»
0.0
LSAT_V11C600328960 G-patch domain-containing protein Lactuca sativa
TI:4236 None
 
A0A9R1V8F7_LACSA
euHCVdb»
0.0
LSAT_V11C600299500 G-patch domain-containing protein Lactuca sativa
TI:4236 None
 
A0ABI7W0Q6_FELCA
Ensembl»
0.0
GPKOW G-patch domain and KOW motifs-containing protein Felis catus
TI:9685 None
   
A7EKY4_SCLS1
TubercuList»
0.0
SS1G_05981 Pre-mRNA-splicing factor Sclerotinia sclerotiorum
TI:5180 None
 
A7RK31_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g238857 G-patch domain-containing protein Nematostella vectensis
TI:45351 None
 
A8INC7_CHLRE
euHCVdb»
0.0
CHLRE_06g303500v5 Uncharacterized protein Chlamydomonas reinhardtii
TI:3055 None
 
A8XRL6_CAEBR
WormBase»
0.0
gkow-1 Protein CBG17653 Caenorhabditis briggsae
TI:6238 None
 
A9V613_MONBE
neXtProt»
0.0
MONBRDRAFT_27691 G-patch domain-containing protein Monosiga brevicollis
TI:81824 None
 
B3RYJ9_TRIAD
CTD»
0.0
TRIADDRAFT_56584 G-patch domain-containing protein Trichoplax adhaerens
TI:10228 None
 
B9GZX9_POPTR
euHCVdb»
0.0
POPTR_003G104200 G-patch domain-containing protein Populus trichocarpa
TI:3694 None
 
B9MUE2_POPTR
euHCVdb»
0.0
POPTR_001G129700 G-patch domain-containing protein Populus trichocarpa
TI:3694 None
 
B9SAH9_RICCO
euHCVdb»
0.0
RCOM_0586970 Protein MOS2, putative Ricinus communis
TI:3988 None
 
C5WQW0_SORBI
euHCVdb»
0.0
SORBI_3001G434500 G-patch domain-containing protein Sorghum bicolor
TI:4558 None
 
C6T4Y8_SOYBN
EnsemblPlants»
0.0
LOC100785211 G-patch domain-containing protein Glycine max
TI:3847 None
 
D7ELY6_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_10613 G patch domain and
KOW motifs-containing protein-like Protein		 Tribolium castaneum
TI:7070 None
 
D8R4Z9_SELML
neXtProt»
0.0
SELMODRAFT_85312 G-patch domain-containing protein Selaginella moellendorffii
TI:88036 None
 
D8S406_SELML
euHCVdb»
0.0
SELMODRAFT_176683 G-patch domain-containing protein Selaginella moellendorffii
TI:88036 None
 
E9HRQ8_DAPPU
neXtProt»
0.0
DAPPUDRAFT_303575 G-patch domain-containing protein Daphnia pulex
TI:6669 None
 
F4P9L0_BATDJ
euHCVdb»
0.0
BATDEDRAFT_26939 G-patch domain-containing protein Batrachochytrium dendrobatidis
TI:109871 None
 
F6HXY8_VITVI
euHCVdb»
0.0
VIT_09s0002g01640 G-patch domain-containing protein Vitis vinifera
TI:29760 None
 
G7IA49_MEDTR
EnsemblPlants»
0.0
MTR_1g038340 DExH-box splicing factor-binding site protein Medicago truncatula
TI:3880 None
 
GPKOW_CAEEL
WormBase»
0.5
gkow-1 G-patch domain and KOW motifs-containing
protein homolog 1 (Protein mos-2 homolog)		 Caenorhabditis elegans
TI:6239 None
 
H2XJM4_CIOIN
Ensembl»
0.0
G-patch domain-containing protein Ciona intestinalis
TI:7719 None
 
I1NCW9_SOYBN
EnsemblPlants»
0.0
LOC100784934 G-patch domain-containing protein Glycine max
TI:3847 None
 
K4AA55_SETIT
EnsemblPlants»
0.0
LOC101755946 G-patch domain-containing protein Setaria italica
TI:4555 None
 
K7L2Q5_SOYBN
EnsemblPlants»
0.0
LOC100784983 G-patch domain-containing protein Glycine max
TI:3847 None
 
K7WF48_MAIZE
EnsemblPlants»
0.0
LOC100501729 Protein MOS2 Zea mays
TI:4577 None
 
M1CW43_SOLTU
EnsemblPlants»
0.0
LOC102593275 Protein MOS2 Solanum tuberosum
TI:4113 None
   
M4D158_BRACM
EnsemblPlants»
0.0
G-patch domain-containing protein Brassica campestris
TI:3711 None
   
M5WHX6_PRUPE
euHCVdb»
0.0
PRUPE_4G208800 Uncharacterized protein Prunus persica
TI:3760 None
 
Q10NZ4_ORYSJ
euHCVdb»
0.0
LOC_Os03g14860 Os03g0253500 G-patch domain containing
protein, expressed (Os03g0253500 protein)		 Oryza sativa
TI:4530 None
 
Q54GS9_DICDI
dictyBase»
0.5
DDB_G0289933 G-patch domain-containing protein Dictyostelium discoideum
TI:44689 None
 
SPP2_EREGS
EnsemblFungi»
0.0
SPP2 Pre-mRNA-splicing factor SPP2 Eremothecium gossypii
TI:33169 None
 
W1PJK3_AMBTC
euHCVdb»
0.0
AMTR_s00018p00151280 G-patch domain-containing protein Amborella trichopoda
TI:13333 None
 
A0A804ISK3_MUSAM
EnsemblPlants»
0.0
GSMUA_128340.1 (wild Malaysian banana) hypothetical protein Musa acuminata
TI:4641 None
 
A0ABM3QTU0_SPIOL
neXtProt»
0.0
LOC110797634 Protein MOS2 Spinacia oleracea
TI:3562 None
   
A0ABM3RDP5_SPIOL
euHCVdb»
0.0
LOC110782105 LOW QUALITY PROTEIN: protein MOS2-like Spinacia oleracea
TI:3562 None
   
A7UVL9_ANOGA
EnsemblMetazoa»
0.0
AgaP_AGAP001551 AGAP001551-PA Anopheles gambiae
TI:7165 None
 
B8CB44_THAPS
neXtProt»
0.0
THAPSDRAFT_24614 Spp2/MOS2 G-patch domain-containing protein Thalassiosira pseudonana
TI:35128 None
 
E3K8R7_PUCGT
TubercuList»
0.0
PGTG_06490 Spp2/MOS2 G-patch domain-containing protein Puccinia graminis
TI:5297 None
 
Q5KND1_CRYD1
TubercuList»
0.0
CNA06910 Spp2/MOS2 G-patch domain-containing protein Cryptococcus deneoformans
TI:40410 None
 
T1F144_HELRO
EnsemblMetazoa»
0.0
20202544 KOW domain-containing protein Helobdella robusta
TI:6412 None
 
A0A1U8Q334_NELNU
euHCVdb»
0.0
LOC109114582 Protein MOS2-like Nelumbo nucifera
TI:4432 None
   
A0A1Z5SAF0_SORBI
euHCVdb»
0.0
SORBI_3001G434450 Uncharacterized protein Sorghum bicolor
TI:4558 None
 
A0A251UWB3_HELAN
euHCVdb»
0.0
MOS2 Putative D111/G-patch domain-containing protein Helianthus annuus
TI:4232 None
 
A0A251VA92_HELAN
neXtProt»
0.0
HannXRQ_Chr03g0083281 HanXRQr2_Chr03g0127621 G-patch domain-containing protein Helianthus annuus
TI:4232 None
 
A0EB76_PARTE
euHCVdb»
0.0
GSPATT00025277001 G-patch domain-containing protein Paramecium tetraurelia
TI:5888 None
 
B7P250_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW000261 G patch domain and
KOW motifs-containing protein, putative		 Ixodes scapularis
TI:6945 None
 
I1H0T1_BRADI
EnsemblPlants»
0.0
BRADI_1g48600v3 G-patch domain-containing protein Brachypodium distachyon
TI:15368 None
 
K4AM61_SETIT
EnsemblPlants»
0.0
KOW domain-containing protein Setaria italica
TI:4555 None
 
Q4QAQ4_LEIMA
TubercuList»
0.0
LMJF_24_0790 Uncharacterized protein Leishmania major
TI:5664 None
 
B1N5X2_ENTH1
TubercuList»
0.0
EHI_200340 Spp2/MOS2 G-patch domain-containing protein Entamoeba histolytica
TI:5759 None
 
C4M5K0_ENTH1
TubercuList»
0.0
EHI_001860 Spp2/MOS2 G-patch domain-containing protein Entamoeba histolytica
TI:5759 None
 
A0A067DES0_CITSI
euHCVdb»
0.0
CISIN_1g044581mg KOW domain-containing protein Citrus sinensis
TI:2711 None
 
A0A067EGW1_CITSI
euHCVdb»
0.0
CISIN_1g038910mg Uncharacterized protein Citrus sinensis
TI:2711 None
 
B7QE66_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW012813 Uncharacterized protein Ixodes scapularis
TI:6945 None