Collated Gene Ontology terms

Biological process: methylcrotonoyl-CoA carboxylase activity(2010, 2014, 2016, 2019, 2021, 2023, 2025) ligase activity(2025) nucleotide binding(2025) ATP binding(2025) transferase activity(2025) propionyl-CoA carboxylase activity(2025) zinc ion binding(2021) ribonuclease III activity(2025) nucleotidyltransferase activity(2025) nuclease activity(2025)
lyase activity2025 hydrolase activity2025 geranoyl-CoA carboxylase activity2019 endonuclease activity2025 double-stranded RNA binding2025 cobalt ion binding2021

Molecular function: L-leucine catabolic process2001, 2002, 2009, 2022, 2024, 2025 coenzyme A metabolic process2010, 2025 terpene catabolic process2019 regulation of eclosion2003 mycolic acid biosynthetic process2010 isoprenoid catabolic process2019 branched-chain amino acid catabolic process2025 RNA processing2025

Cellular component: methylcrotonoyl-CoA carboxylase complex2016, 2017, 2024, 2025 mitochondrion2001, 2003, 2005, 2009, 2014, 2016, 2018, 2021, 2024, 2025 mitochondrial matrix2021, 2024, 2025 ribosome2025 ribonucleoprotein complex2025 plasma membrane2019 cytosol2013 cytoplasm2012

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 9/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 2/4 
Harosa: 3/4 
Hacrobia: 0/0 
Plants: 38/39 
Archea: 1/8 
Bacteria: 13/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
A0A8V0ZWN0_CHICK
Ensembl»
1.0
MCCC2L methylcrotonoyl-CoA carboxylase (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA
carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta)		 Gallus gallus
TI:9031 None
   
A9C3S0_DANRE
ZFIN»
1.0
si:ch211-198n5.11 methylcrotonoyl-CoA carboxylase (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA
carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta)		 Danio rerio
TI:7955 None
 
F1P531_CHICK
Ensembl»
1.0
MCCC2 Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase
2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta)		 Gallus gallus
TI:9031 None
   
MCCB_ARATH
TAIR»
2.8
MCCB Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC
6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta)		 Arabidopsis thaliana
TI:3702 None
 
MCCB_CAEEL
WormBase»
1.0
mccc-2 Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4)
(3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta)		 Caenorhabditis elegans
TI:6239 None
 
MCCB_DICDI
dictyBase»
1.0
mccb Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA
carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta)		 Dictyostelium discoideum
TI:44689 None
 
MCCB_DROME
FlyBase»
3.6
Mccc2 Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4)
(3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta)		 Drosophila melanogaster
TI:7227 None
 
MCCB_HUMAN
Ensembl»
4.7
MCCC2 Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA
carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta)		 Homo sapiens
TI:9606 None
 
MCCB_MOUSE
Ensembl»
3.0
Mccc2 Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA
carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta)		 Mus musculus
TI:10090 None
 
MCCB_RAT
RGD»
4.1
Mccc2 Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA
carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta)		 Rattus norvegicus
TI:10116 None
 
Q6NWI5_DANRE
ZFIN»
1.0
mccc2 Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase
2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta)		 Danio rerio
TI:7955 None