Collated Gene Ontology terms

Biological process: S-formylglutathione hydrolase activity(2006, 2007, 2011, 2013, 2017, 2024) hydrolase activity, acting on ester bonds(2008, 2014, 2024) carboxylic ester hydrolase activity(2001, 2019, 2024) identical protein binding(2020, 2024) hydrolase activity(2024) serine hydrolase activity(2021) methylumbelliferyl-acetate deacetylase activity(2024) metal ion binding(2024) hydroxyacylglutathione hydrolase activity(2007) G protein-coupled receptor activity(2024)

Molecular function: formaldehyde catabolic process2006, 2007, 2013, 2019, 2024 formaldehyde metabolic process2021, 2024 protein homotetramerization2020 cell redox homeostasis2021 G protein-coupled receptor signaling pathway2024

Cellular component: cytosol2006, 2013, 2017, 2019, 2024 cytoplasm2024 cytoplasmic vesicle2024 protein-containing complex2019 membrane2024 extracellular exosome2014 endoplasmic reticulum lumen2015 apoplast2021

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 11/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 37/39 
Archea: 1/8 
Bacteria: 12/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
SFGH_ARATH
TAIR»
0.8
SFGH S-formylglutathione hydrolase (AtSFGH)
(EC 3.1.2.12) (Esterase D)		 Arabidopsis thaliana
TI:3702 None
 
G5EF86_CAEEL
WormBase»
0.5
CELE_Y48G10A.1 Y48G10A.1 S-formylglutathione hydrolase (EC 3.1.2.12) Caenorhabditis elegans
TI:6239 None
 
Q567K2_DANRE
ZFIN»
0.5
fb58f05 S-formylglutathione hydrolase (EC 3.1.2.12) Danio rerio
TI:7955 None
 
Q54RL8_DICDI
dictyBase»
1.5
esd S-formylglutathione hydrolase (EC 3.1.2.12) Dictyostelium discoideum
TI:44689 None
 
Q7KSB5_DROME
FlyBase»
1.0
Dmel\CG4390 S-formylglutathione hydrolase (EC 3.1.2.12) Drosophila melanogaster
TI:7227 None
 
SFGH1_ECOLI
EnsemblBacteria»
2.1
frmB S-formylglutathione hydrolase FrmB
(FGH) (EC 3.1.2.12)		 Escherichia coli
TI:562 None
 
SFGH2_ECOLI
EnsemblBacteria»
4.5
yeiG S-formylglutathione hydrolase YeiG
(FGH) (EC 3.1.2.12)		 Escherichia coli
TI:562 None
 
A0A8V0XAV4_CHICK
Ensembl»
0.0
ESD S-formylglutathione hydrolase (EC 3.1.2.12) Gallus gallus
TI:9031 None
   
ESTD_HUMAN
Ensembl»
2.7
ESD S-formylglutathione hydrolase (FGH) (EC 3.1.2.12)
(Esterase D) (Methylumbelliferyl-acetate deacetylase) (EC 3.1.1.56)		 Homo sapiens
TI:9606 None
 
ESTD_MOUSE
Ensembl»
0.8
Esd S-formylglutathione hydrolase (FGH) (EC 3.1.2.12)
(Esterase 10) (Esterase D) (Sid 478)		 Mus musculus
TI:10090 None
 
A0A0G2JYG2_RAT
RGD»
0.5
AABR07062298.1 S-formylglutathione hydrolase (EC
3.1.2.12) (Esterase D)		 Rattus norvegicus
TI:10116 None
   
ESTD_RAT
RGD»
1.5
Esd S-formylglutathione hydrolase (FGH)
(EC 3.1.2.12) (Esterase D)		 Rattus norvegicus
TI:10116 None
 
SFGH_YEAST
SGD»
2.1
YJL068C S-formylglutathione hydrolase
(FGH) (EC 3.1.2.12)		 Saccharomyces cerevisiae
TI:4932 None