Collated Gene Ontology terms

Biological process: 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity(2004, 2011, 2013, 2014, 2022, 2024) zinc ion binding(2014, 2022, 2024) metal ion binding(2024) methyltransferase activity(2024) S-methyltransferase activity(2024) methionine synthase activity(2005, 2010, 2015, 2017, 2019, 2024) mRNA binding(2020) copper ion binding(2019) RNA endonuclease activity(2024) RNA binding(2024)

Molecular function: methionine biosynthetic process2004, 2010, 2013, 2014, 2015, 2019, 2022, 2024 methylation2024 amino acid biosynthetic process2024 L-methionine biosynthetic process from homoserine via O-acetyl-L-homoserine and cystathionine2014, 2024 'de novo' L-methionine biosynthetic process2022 methionine metabolic process2014 tetrahydrofolate interconversion2015 response to zinc ion2010 modulation by symbiont of host immune response2024 homocysteine metabolic process2015
ergosterol biosynthetic process2021 defense response to virus2024 cysteine metabolic process2009 cellular response to heat2014 RNA-mediated gene silencing2024 DNA methylation-dependent heterochromatin formation2019

Cellular component: cytosol2005, 2009, 2010, 2014, 2017, 2019, 2022, 2024 chloroplast2005, 2021, 2024 cytoplasm2018, 2024 plasma membrane2010, 2018, 2021 nucleus2009, 2017, 2024 plasmodesma2021 peroxisome2013, 2021 membrane2024 apoplast2021 ribonucleoprotein complex2024
plant-type vacuole2021 peptidoglycan-based cell wall2012 hyphal cell wall2014 fungal-type cell wall2014 fungal biofilm matrix2016 extracellular region2012 chloroplast stroma2021 chloroplast envelope2021 cell surface2014 Golgi apparatus2012

Phylogenetic distribution

Chordates: 1/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 0/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 0/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 13/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 2/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 38/39 
Archea: 4/8 
Bacteria: 22/35 

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Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

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Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
METE1_ARATH
TAIR»
6.9
MS1 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 1 (EC 2.1.1.14) (Cobalamin-independent methionine
synthase 1) (AtMS1) (Vitamin-B12-independent methionine synthase 1)		 Arabidopsis thaliana
TI:3702 None
 
METE2_ARATH
TAIR»
2.4
MS2 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 2 (EC 2.1.1.14)
(Cobalamin-independent methionine synthase 2) (AtMS2)		 Arabidopsis thaliana
TI:3702 None
 
METE3_ARATH
TAIR»
1.6
MS3 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 3, chloroplastic (EC
2.1.1.14) (Cobalamin-independent methionine synthase 3) (AtMS3)		 Arabidopsis thaliana
TI:3702 None
 
METE_DICDI
dictyBase»
1.0
metE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) (Cobalamin-independent methionine
synthase) (Methionine synthase, vitamin-B12 independent isozyme)		 Dictyostelium discoideum
TI:44689 None
 
METE_ECOLI
EnsemblBacteria»
4.0
metE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) (Cobalamin-independent methionine
synthase) (Methionine synthase, vitamin-B12 independent isozyme)		 Escherichia coli
TI:562 None
 
METE_SCHPO
PomBase»
2.2
met26 Probable 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) (Cobalamin-independent
methionine synthase) (Methionine synthase, vitamin-B12 independent isozyme)		 Schizosaccharomyces pombe
TI:4896 None
 
METE_YEAST
SGD»
2.2
MET6 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) (Cobalamin-independent methionine synthase)
(Delta-P8 protein) (Methionine synthase, vitamin-B12 independent isozyme)		 Saccharomyces cerevisiae
TI:4932 None
 
Q55G42_DICDI
dictyBase»
0.0
DDB_G0267834 Cobalamin-independent methionine synthase
MetE C-terminal/archaeal domain-containing protein		 Dictyostelium discoideum
TI:44689 None