Collated Gene Ontology terms

Biological process: protein-folding chaperone binding(2005, 2013, 2017, 2021, 2025) nucleotide binding(2025) ATP binding(2025) ABC-type protein transporter activity(2003, 2025) protein-macromolecule adaptor activity(2013, 2025) protein-transporting ATPase activity(2004, 2007) protein serine/threonine kinase activity(2025) protein kinase activity(2025) enzyme binding(2025) DNA binding(2025)
ATP-dependent DNA damage sensor activity2025 ATP hydrolysis activity2023

Molecular function: protein import into mitochondrial matrix2004, 2016, 2017, 2021, 2025 protein transport2025 protein targeting to mitochondrion2003, 2004, 2007, 2025 establishment of protein localization2025 intracellular protein transport2005, 2024, 2025 signal transduction2025 response to 3,3',5-triiodo-L-thyronine2017 protein transmembrane transport2025 cellular response to hypoxia2011 cardiac muscle cell differentiation2017
DNA repair2025

Cellular component: mitochondrial inner membrane2005, 2007, 2011, 2014, 2019, 2024, 2025 TIM23 mitochondrial import inner membrane translocase complex2003, 2016, 2023, 2025 mitochondrion2007, 2009, 2018, 2021, 2024, 2025 mitochondrial matrix2011, 2025 PAM complex, Tim23 associated import motor2004, 2013, 2021, 2025 extrinsic component of mitochondrial inner membrane2016, 2025 plasma membrane2014 nucleus2025 membrane2025 fibrillar center2025
cytoplasm2025

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 15/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 1/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 39/39 
Archea: 0/8 
Bacteria: 1/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
Q9VDZ7_DROME
FlyBase»
2.8
CG117799 Mitochondrial import inner
membrane translocase subunit TIM44		 Drosophila melanogaster
TI:7227 None
 
TIM44_YEAST
SGD»
4.8
TIM44 Mitochondrial import inner membrane translocase subunit TIM44 (Inner membrane import site protein
45) (ISP45) (Membrane import machinery protein MIM44) (Mitochondrial protein import protein 1)		 Saccharomyces cerevisiae
TI:4932 None
 
TI441_ARATH
TAIR»
2.8
TIM44-1 Mitochondrial import inner
membrane translocase subunit TIM44-1		 Arabidopsis thaliana
TI:3702 None
 
TI442_ARATH
TAIR»
2.8
TIM44-2 Mitochondrial import inner
membrane translocase subunit TIM44-2		 Arabidopsis thaliana
TI:3702 None
 
F1NU71_CHICK
Ensembl»
0.0
TIMM44 Mitochondrial import inner
membrane translocase subunit TIM44		 Gallus gallus
TI:9031 None
   
TIM44_HUMAN
Ensembl»
2.5
TIMM44 Mitochondrial import inner
membrane translocase subunit TIM44		 Homo sapiens
TI:9606 None
 
TIM44_MOUSE
Ensembl»
2.5
Timm44 Mitochondrial import inner
membrane translocase subunit TIM44		 Mus musculus
TI:10090 None
 
TIM44_RAT
RGD»
4.2
Timm44 Mitochondrial import inner
membrane translocase subunit TIM44		 Rattus norvegicus
TI:10116 None
 
TIM44_SCHPO
PomBase»
3.0
tim44 Mitochondrial import inner
membrane translocase subunit tim44		 Schizosaccharomyces pombe
TI:4896 None
 
Q5BLH8_DANRE
ZFIN»
1.0
timm44 Mitochondrial import inner
membrane translocase subunit TIM44		 Danio rerio
TI:7955 None
 
TIM44_CAEEL
WormBase»
1.0
tin-44 Probable mitochondrial import inner
membrane translocase subunit tin-44		 Caenorhabditis elegans
TI:6239 None