Collated Gene Ontology terms

Biological process: splicing factor binding(2016) small molecule binding(2022) potassium channel activity(2016) lipid binding(2022) intracellular calcium activated chloride channel activity(2016) RNA binding(2014)

Molecular function: spliceosomal snRNP assembly2013, 2018, 2023, 2024 mRNA cis splicing, via spliceosome2013, 2021, 2023, 2024 chloride transport2005, 2024 cell volume homeostasis2005, 2024 mRNA processing2024 RNA splicing2024 positive regulation of mRNA splicing, via spliceosome2018, 2023 negative regulation of cell volume2016 potassium ion transmembrane transport2016 chloride transmembrane transport2016
axon extension2005

Cellular component: cytosol2009, 2013, 2016, 2023, 2024 pICln-Sm protein complex2013, 2023, 2024 nucleus2009, 2014, 2018, 2023, 2024 cytoplasm2014, 2018, 2024 spliceosomal complex2014, 2021, 2024 methylosome2013, 2018, 2023, 2024 plasma membrane2003, 2024 nucleoplasm2023, 2024 cytoskeleton2024 protein-containing complex2016
membrane2016

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 11/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 37/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
ICLN_HUMAN
Ensembl»
3.5
CLNS1A Methylosome subunit pICln (Chloride channel, nucleotide sensitive 1A) (Chloride conductance regulatory
protein ICln) (I(Cln)) (Chloride ion current inducer protein) (ClCI) (Reticulocyte pICln)		 Homo sapiens
TI:9606 None
 
ICLN_ARATH
TAIR»
0.0
At5g62290 Chloride conductance regulatory protein ICln (I(Cln))
(Chloride ion current inducer protein) (ClCI)		 Arabidopsis thaliana
TI:3702 None
 
ICLN_DROME
FlyBase»
1.0
icln Methylosome subunit pICln Drosophila melanogaster
TI:7227 None
 
ICLN_RAT
RGD»
4.1
Clns1a Methylosome subunit pICln (Chloride channel, nucleotide sensitive
1A) (Chloride conductance regulatory protein ICln) (I(Cln))		 Rattus norvegicus
TI:10116 None
 
LOT5_YEAST
SGD»
1.0
LOT5 Protein LOT5 (Low
temperature-responsive protein 5)		 Saccharomyces cerevisiae
TI:4932 None
 
G5EG22_CAEEL
WormBase»
1.0
icln-1 Methylosome subunit pICln Caenorhabditis elegans
TI:6239 None
 
ICLN_MOUSE
AG»
2.5
Clns1a Methylosome subunit pICln (Chloride channel, nucleotide sensitive 1A) (Chloride conductance
regulatory protein ICln) (I(Cln)) (Chloride ion current inducer protein) (ClCI)		 Mus musculus
TI:10090 None
 
ICLN_SCHPO
PomBase»
2.6
saf5 Splicing factor saf5 Schizosaccharomyces pombe
TI:4896 None
 
Q54Q91_DICDI
dictyBase»
1.0
DDB_G0284021 Methylosome subunit pICln Dictyostelium discoideum
TI:44689 None
 
Q7ZTV8_DANRE
ZFIN»
1.8
icln Methylosome subunit pICln (Chloride
conductance regulatory protein ICln)		 Danio rerio
TI:7955 None
 
A0A8I5ZMA5_RAT
RGD»
0.0
ENSRNOG00000068015 Methylosome subunit pICln (Chloride channel, nucleotide
sensitive 1A) (Chloride conductance regulatory protein ICln)		 Rattus norvegicus
TI:10116 None
   
A0A8V0X4F1_CHICK
Ensembl»
0.0
CLNS1A Methylosome subunit pICln (Chloride
conductance regulatory protein ICln)		 Gallus gallus
TI:9031 None