Collated Gene Ontology terms

Biological process: splicing factor binding(2016) small molecule binding(2022) potassium channel activity(2016) lipid binding(2022) intracellularly calcium-gated chloride channel activity(2016) enzyme inhibitor activity(2025) RNA binding(2014)

Molecular function: spliceosomal snRNP assembly2013, 2023, 2024, 2025 mRNA cis splicing, via spliceosome2013, 2021, 2023, 2025 chloride transport2005, 2025 cell volume homeostasis2005, 2025 mRNA processing2025 RNA splicing2025 mRNA splicing, via spliceosome2022, 2025 potassium ion transmembrane transport2025 positive regulation of mRNA splicing, via spliceosome2024, 2025 chloride transmembrane transport2025
positive regulation of mRNA cis splicing, via spliceosome2024 axon extension2005

Cellular component: cytosol2009, 2013, 2016, 2018, 2023, 2025 pICln-Sm protein complex2013, 2023, 2025 nucleus2009, 2014, 2018, 2022, 2024, 2025 spliceosomal complex2014, 2021, 2025 cytoplasm2014, 2018, 2022, 2025 methylosome2013, 2022, 2025 plasma membrane2003, 2025 cytoskeleton2025 nucleoplasm2024, 2025 microtubule cytoskeleton2024, 2025
protein-containing complex2016 membrane2016 sperm principal piece2025 sperm midpiece2025 sperm head-tail coupling apparatus2025 cilium2025

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 12/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 39/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
ICLN_ARATH
TAIR»
1.8
At5g62290 Chloride conductance regulatory protein ICln (I(Cln))
(Chloride ion current inducer protein) (ClCI)		 Arabidopsis thaliana
TI:3702 None
 
G5EG22_CAEEL
WormBase»
1.0
icln-1 Methylosome subunit pICln Caenorhabditis elegans
TI:6239 None
 
ICLN_DROME
FlyBase»
1.0
icln Methylosome subunit pICln Drosophila melanogaster
TI:7227 None
 
Q54Q91_DICDI
dictyBase»
1.0
DDB_G0284021 Methylosome subunit pICln Dictyostelium discoideum
TI:44689 None
 
A0A8V0X4F1_CHICK
Ensembl»
1.0
CLNS1A Methylosome subunit pICln (Chloride
conductance regulatory protein ICln)		 Gallus gallus
TI:9031 None
   
Q7ZTV8_DANRE
ZFIN»
1.8
clns1a Methylosome subunit pICln (Chloride
conductance regulatory protein ICln)		 Danio rerio
TI:7955 None
 
ICLN_RAT
RGD»
6.1
Clns1a Methylosome subunit pICln (Chloride channel, nucleotide sensitive
1A) (Chloride conductance regulatory protein ICln) (I(Cln))		 Rattus norvegicus
TI:10116 None
 
ICLN_MOUSE
AG»
4.2
Clns1a Methylosome subunit pICln (Chloride channel, nucleotide sensitive 1A) (Chloride conductance
regulatory protein ICln) (I(Cln)) (Chloride ion current inducer protein) (ClCI)		 Mus musculus
TI:10090 None
 
ICLN_HUMAN
Ensembl»
3.5
CLNS1A Methylosome subunit pICln (Chloride channel, nucleotide sensitive 1A) (Chloride conductance regulatory
protein ICln) (I(Cln)) (Chloride ion current inducer protein) (ClCI) (Reticulocyte pICln)		 Homo sapiens
TI:9606 None
 
LOT5_YEAST
SGD»
1.8
LOT5 Protein LOT5 (Low
temperature-responsive protein 5)		 Saccharomyces cerevisiae
TI:4932 None
 
ICLN_SCHPO
PomBase»
3.4
saf5 Splicing factor saf5 Schizosaccharomyces pombe
TI:4896 None