Collated Gene Ontology terms

Biological process: membrane insertase activity(2020, 2022, 2024) transmembrane transporter activity(2024)

Molecular function: protein insertion into ER membrane by stop-transfer membrane-anchor sequence2020, 2024 tail-anchored membrane protein insertion into ER membrane2020, 2022, 2024 protein folding in endoplasmic reticulum2019, 2024 phospholipid transport2016, 2024 phospholipid metabolic process2016, 2024 transmembrane transport2024 protein insertion into ER membrane2020 piecemeal microautophagy of the nucleus2021 exocytosis2021 cytoplasm to vacuole transport by the Cvt pathway2021

Cellular component: EMC complex2012, 2016, 2017, 2020, 2024 endoplasmic reticulum membrane2020, 2024 membrane2012, 2024 endoplasmic reticulum2009, 2014, 2018, 2021, 2024 protein-containing complex2018, 2024 plasma membrane2021 plant-type vacuole2021 endomembrane system2014 Golgi apparatus2021

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 2/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 37/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
A0A022RNC5_ERYGU
EnsemblFungi»
0.0
MIMGU_mgv1a000799mg ER membrane protein complex subunit 1 Erythranthe guttata
TI:4155 None
 
A0A061GJM6_THECC
EnsemblPlants»
0.0
TCM_037167 ER membrane protein complex subunit 1 Theobroma cacao
TI:3641 None
 
A0A067GJ73_CITSI
Ensembl»
0.0
CISIN_1g002016mg ER membrane protein complex subunit 1 Citrus sinensis
TI:2711 None
 
A0A072V1X3_MEDTR
EnsemblPlants»
0.0
MTR_3g110090 ER membrane protein complex subunit 1 Medicago truncatula
TI:3880 None
 
A0A072V2Z0_MEDTR
EnsemblPlants»
0.0
25490115 ER membrane protein complex subunit 1 Medicago truncatula
TI:3880 None
 
A0A078JRD8_BRANA
EnsemblPlants»
0.0
BnaCnng57230D BnaCnng57230D protein Brassica napus
TI:3708 None
 
A0A078JSY4_BRANA
EnsemblPlants»
0.0
BnaCnng59410D ER membrane protein complex subunit 1 Brassica napus
TI:3708 None
 
A0A0A0LS33_CUCSA
EnsemblPlants»
0.0
Csa_2G375170 ER membrane protein complex subunit 1 Cucumis sativus
TI:3659 None
 
A0A0K9P6R7_ZOSMR
EnsemblPlants»
0.0
ZOSMA_38G00010 ER membrane protein complex subunit 1 Zostera marina
TI:29655 None
 
A0A0K9Q1W9_ZOSMR
EnsemblPlants»
0.0
ZOSMA_126G00130 ER membrane protein complex subunit 1 Zostera marina
TI:29655 None
 
A0A1D6FQV1_MAIZE
EnsemblPlants»
0.0
ZEAMMB73_Zm00001d010413 ER membrane protein complex subunit 1 Zea mays
TI:4577 None
 
A0A1D6M0B8_MAIZE
EnsemblPlants»
0.0
100381974 ER membrane protein complex subunit 1 Zea mays
TI:4577 None
 
A0A1D8PN56_CANAL
EnsemblFungi»
0.0
CAALFM_C501410CA orf19.11608 ER membrane protein complex subunit 1 Candida albicans
TI:5476 None
 
A0A1S3ZWD6_TOBAC
EnsemblFungi»
0.0
LOC107791146 ER membrane protein complex subunit 1-like Nicotiana tabacum
TI:4097 None
   
A0A1S4AJ77_TOBAC
EnsemblFungi»
0.0
LOC107798297 ER membrane protein complex subunit 1 Nicotiana tabacum
TI:4097 None
   
A0A1S4BHD6_TOBAC
EnsemblFungi»
0.0
LOC107808270 ER membrane protein complex subunit 1 Nicotiana tabacum
TI:4097 None
   
A0A1S4CC66_TOBAC
EnsemblFungi»
0.0
LOC107817260 ER membrane protein complex subunit 1 Nicotiana tabacum
TI:4097 None
   
A0A1U7ZJA4_NELNU
EnsemblBacteria»
0.0
LOC104595143 ER membrane protein complex subunit 1 Nelumbo nucifera
TI:4432 None
   
A0A1U8IYC1_GOSHI
Ensembl»
0.0
LOC107901545 ER membrane protein complex subunit 1 Gossypium hirsutum
TI:3635 None
   
A0A1U8MI50_GOSHI
Ensembl»
0.0
LOC107937971 ER membrane protein complex subunit 1 Gossypium hirsutum
TI:3635 None
   
A0A1U8N6B8_GOSHI
Ensembl»
0.0
LOC107944095 ER membrane protein complex subunit 1 Gossypium hirsutum
TI:3635 None
   
A0A1U8PXC9_GOSHI
Ensembl»
0.0
LOC107962887 ER membrane protein complex subunit 1 Gossypium hirsutum
TI:3635 None
   
A0A1Y1ID68_KLENI
EnsemblPlants»
0.0
KFL_004680080 ER membrane protein complex subunit 1 Klebsormidium nitens
TI:105231 None
 
A0A251RD06_PRUPE
EnsemblPlants»
0.0
PRUPE_1G450600 ER membrane protein complex subunit 1 Prunus persica
TI:3760 None
 
A0A251U7I1_HELAN
EnsemblPlants»
0.0
HannXRQ_Chr08g0221151 HanXRQr2_Chr12g0555271 ER membrane protein complex subunit 1 Helianthus annuus
TI:4232 None
 
A0A2C9W525_MANES
EnsemblPlants»
0.0
MANES_03G061800 ER membrane protein complex subunit 1 Manihot esculenta
TI:3983 None
 
A0A2G2ZBI1_CAPAN
EnsemblPlants»
0.0
T459_17410 ER membrane protein complex subunit 1 Capsicum annuum
TI:4072 None
 
A0A2I2UQA2_FELCA
Ensembl»
0.0
EMC1 ER membrane protein complex subunit 1 Felis catus
TI:9685 None
 
A0A2I4GFA7_JUGRE
EnsemblPlants»
0.0
LOC109007375 ER membrane protein complex subunit 1 Juglans regia
TI:51240 None
 
A0A2I4GNQ6_JUGRE
EnsemblPlants»
0.0
LOC109009503 ER membrane protein complex subunit 1 Juglans regia
TI:51240 None
   
A0A2K1WVJ7_POPTR
EnsemblPlants»
0.0
POPTR_018G039800 ER membrane protein complex subunit 1 Populus trichocarpa
TI:3694 None
 
A0A2K2A7D7_POPTR
EnsemblPlants»
0.0
POPTR_006G240300 ER membrane protein complex subunit 1 Populus trichocarpa
TI:3694 None
 
A0A2K3E7I4_CHLRE
EnsemblPlants»
0.0
CHLRE_01g042550v5 ER membrane protein complex subunit 1 Chlamydomonas reinhardtii
TI:3055 None
 
A0A2R6XV44_MARPO
EnsemblPlants»
0.0
MARPO_0001s0045 ER membrane protein complex subunit 1 Marchantia polymorpha
TI:3197 None
 
A0A3B5XX70_WHEAT
EnsemblPlants»
0.0
ER membrane protein complex subunit 1 Triticum aestivum
TI:4565 None
   
A0A3B5YUK0_WHEAT
EnsemblPlants»
0.0
CFC21_006173 ER membrane protein complex subunit 1 Triticum aestivum
TI:4565 None
 
A0A3B5ZSP2_WHEAT
EnsemblPlants»
0.0
CFC21_010937 ER membrane protein complex subunit 1 Triticum aestivum
TI:4565 None
 
A0A3Q1M901_BOVIN
Ensembl»
0.0
EMC1 ER membrane protein complex subunit 1 Bos taurus
TI:9913 None
   
A0A3Q7HWY2_SOLLC
EnsemblPlants»
0.0
ER membrane protein complex subunit 1 Solanum lycopersicum
TI:4081 None
   
A0A5G2QQ04_PIG
Ensembl»
0.0
EMC1 ER membrane protein complex subunit 1 Sus scrofa
TI:9823 None
   
A0A7M7NXZ4_STRPU
EnsemblMetazoa»
0.0
ER membrane protein complex subunit 1 Strongylocentrotus purpuratus
TI:7668 None
   
A0A803SMM0_ANOCA
Ensembl»
0.0
ER membrane protein complex subunit 1 Anolis carolinensis
TI:28377 None
   
A0A804ILM9_MUSAM
EnsemblPlants»
0.0
103980749 ER membrane protein complex subunit 1 Musa acuminata
TI:4641 None
 
A0A804IP65_MUSAM
EnsemblPlants»
0.0
GSMUA_118210.1 ER membrane protein complex subunit 1 Musa acuminata
TI:4641 None
 
A0A8I3RRF6_CANLF
Ensembl»
0.0
EMC1 ER membrane protein complex subunit 1 Canis lupus
TI:9612 None
   
A0A8J0T8C8_XENLA
Xenbase»
0.0
emc1.L ER membrane protein complex subunit 1 Xenopus laevis
TI:8355 None
   
A0A8J0TDX4_XENLA
Xenbase»
0.0
emc1.S ER membrane protein complex subunit 1 Xenopus laevis
TI:8355 None
   
A0A8M2B912_DANRE
CTD»
0.0
emc1 ER membrane protein complex subunit 1 Danio rerio
TI:7955 None
   
A0A8R1Z5I5_PRIPA
EnsemblMetazoa»
0.0
WBGene00304454 ER membrane protein complex subunit 1 Pristionchus pacificus
TI:54126 None
   
A0A8V0ZEQ3_CHICK
Ensembl»
0.0
EMC1 ER membrane protein complex subunit 1 Gallus gallus
TI:9031 None
   
A0A9J7L739_BRAFL
CTD»
0.0
LOC118415936 ER membrane protein complex subunit 1 Branchiostoma floridae
TI:7739 None
   
A0BUA3_PARTE
EnsemblProtists»
0.0
GSPATT00032352001 ER membrane protein complex subunit 1 Paramecium tetraurelia
TI:5888 None
 
A0CJK9_PARTE
EnsemblProtists»
0.0
GSPATT00000688001 ER membrane protein complex subunit 1 Paramecium tetraurelia
TI:5888 None
 
A0E6E8_PARTE
EnsemblProtists»
0.0
GSPATT00003730001 ER membrane protein complex subunit 1 Paramecium tetraurelia
TI:5888 None
 
A7ED32_SCLS1
EnsemblFungi»
0.0
SS1G_03221 ER membrane protein complex subunit 1 Sclerotinia sclerotiorum
TI:5180 None
 
A7RNR6_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g234273 ER membrane protein complex subunit 1 Nematostella vectensis
TI:45351 None
 
A7T4B3_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g145387 ER membrane protein complex subunit 1 Nematostella vectensis
TI:45351 None
 
A8X3R8_CAEBR
WormBase»
0.0
emc-1 ER membrane protein complex subunit 1 Caenorhabditis briggsae
TI:6238 None
 
A9SFI2_PHYPA
EnsemblPlants»
0.0
PHYPA_028752 ER membrane protein complex subunit 1 Physcomitrium patens
TI:3218 None
 
A9UPJ8_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_30835 ER membrane protein complex subunit 1 Monosiga brevicollis
TI:81824 None
 
B3S0A1_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_37902 ER membrane protein complex subunit 1 Trichoplax adhaerens
TI:10228 None
 
B6K2G8_SCHJY
EnsemblFungi»
0.0
SJAG_02437 ER membrane protein complex subunit 1 Schizosaccharomyces japonicus
TI:4897 None
 
B7PJJ4_IXOSC
EnsemblMetazoa»
0.0
8029887 ER membrane protein complex subunit 1 Ixodes scapularis
TI:6945 None
 
B8C9T9_THAPS
EnsemblProtists»
0.0
THAPSDRAFT_24233 ER membrane protein complex subunit 1 Thalassiosira pseudonana
TI:35128 None
 
B9RS37_RICCO
EnsemblBacteria»
0.0
RCOM_0802660 ER membrane protein complex subunit 1 Ricinus communis
TI:3988 None
 
C4LWD8_ENTH1
EnsemblProtists»
0.0
EHI_096250 ER membrane protein complex subunit 1 Entamoeba histolytica
TI:5759 None
 
C5YV63_SORBI
EnsemblPlants»
0.0
SORBI_3009G084900 ER membrane protein complex subunit 1 Sorghum bicolor
TI:4558 None
 
D4A994_RAT
RGD»
1.5
Emc1 ER membrane protein complex subunit 1 Rattus norvegicus
TI:10116 None
   
D6WIT7_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_02407 ER membrane protein complex subunit 1 Tribolium castaneum
TI:7070 None
 
D7SUC3_VITVI
EnsemblPlants»
0.0
VIT_04s0008g03620 ER membrane protein complex subunit 1 Vitis vinifera
TI:29760 None
 
D8QUF2_SELML
EnsemblPlants»
0.0
SELMODRAFT_165412 ER membrane protein complex subunit 1 Selaginella moellendorffii
TI:88036 None
 
D8R415_SELML
EnsemblPlants»
0.0
SELMODRAFT_84520 ER membrane protein complex subunit 1 Selaginella moellendorffii
TI:88036 None
 
E3KH97_PUCGT
EnsemblFungi»
0.0
PGTG_09385 ER membrane protein complex subunit 1 Puccinia graminis
TI:5297 None
 
E9GF57_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_211018 ER membrane protein complex subunit 1 Daphnia pulex
TI:6669 None
 
EMC1_CHICK
CTD»
1.5
EMC1 ER membrane protein complex subunit 1 Gallus gallus
TI:9031 None
 
EMC1_HUMAN
Ensembl»
3.2
EMC1 ER membrane protein complex subunit 1 Homo sapiens
TI:9606 None
 
EMC1_MOUSE
Ensembl»
2.5
Emc1 ER membrane protein complex subunit 1 Mus musculus
TI:10090 None
 
EMC1_SCHPO
PomBase»
1.5
emc1 ER membrane protein complex subunit 1 Schizosaccharomyces pombe
TI:4896 None
 
EMC1_XENLA
Xenbase»
0.0
emc1 ER membrane protein complex subunit 1 Xenopus laevis
TI:8355 None
 
EMC1_YEAST
SGD»
3.7
EMC1 ER membrane protein complex subunit 1 Saccharomyces cerevisiae
TI:4932 None
 
F0ZNI9_DICPU
EnsemblProtists»
0.0
DICPUDRAFT_34933 ER membrane protein complex subunit 1 Dictyostelium purpureum
TI:5786 None
 
F2D6F2_HORVV
EnsemblPlants»
0.0
ER membrane protein complex subunit 1 Hordeum vulgare
TI:4513 None
 
F4JXW9_ARATH
TAIR»
0.0
At5g11560 ER membrane protein complex subunit 1 Arabidopsis thaliana
TI:3702 None
 
F4P4D9_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_89405 Anaphase-promoting complex subunit
4 WD40 domain-containing protein		 Batrachochytrium dendrobatidis
TI:109871 None
 
F4P4E0_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_89083 ER membrane protein complex subunit 1 Batrachochytrium dendrobatidis
TI:109871 None
 
F6TUQ9_XENTR
Xenbase»
0.0
emc1 ER membrane protein complex subunit 1 Xenopus tropicalis
TI:8364 None
   
F6U072_HORSE
Ensembl»
0.0
EMC1 ER membrane protein complex subunit 1 Equus caballus
TI:9796 None
   
F7BRB3_MONDO
Ensembl»
0.0
EMC1 ER membrane protein complex subunit 1 Monodelphis domestica
TI:13616 None
   
F7C0Z3_ORNAN
Ensembl»
0.0
EMC1 ER membrane protein complex subunit 1 Ornithorhynchus anatinus
TI:9258 None
   
F7FSE2_MACMU
Ensembl»
0.0
EMC1 ER membrane protein complex subunit 1 Macaca mulatta
TI:9544 None
   
G3QE37_GORGO
Ensembl»
0.0
EMC1 ER membrane protein complex subunit 1 Gorilla gorilla
TI:9593 None
 
H2L0C0_CAEEL
WormBase»
0.0
emc-1 ER membrane protein complex subunit 1 Caenorhabditis elegans
TI:6239 None
 
H2LGW1_ORYLA
Ensembl»
0.0
emc1 ER membrane protein complex subunit 1 Oryzias latipes
TI:8090 None
   
H2R9E3_PANTR
Ensembl»
0.0
EMC1 ER membrane protein complex subunit 1 Pan troglodytes
TI:9598 None
 
H2Y0W0_CIOIN
Ensembl»
0.0
LOC100177708 ER membrane protein complex subunit 1 Ciona intestinalis
TI:7719 None
   
H3GWY1_PHYRM
EnsemblProtists»
0.0
ER membrane protein complex subunit 1 Phytophthora ramorum
TI:164328 None
 
I1HKT4_BRADI
EnsemblPlants»
0.0
100839696 ER membrane protein complex subunit 1 Brachypodium distachyon
TI:15368 None
 
I1JUT9_SOYBN
EnsemblPlants»
0.0
100807708 ER membrane protein complex subunit 1 Glycine max
TI:3847 None
 
I1K9B8_SOYBN
EnsemblPlants»
0.0
100790095 ER membrane protein complex subunit 1 Glycine max
TI:3847 None
 
K3Z3H2_SETIT
EnsemblPlants»
0.0
101757400 ER membrane protein complex subunit 1 Setaria italica
TI:4555 None
 
M1AZN8_SOLTU
EnsemblPlants»
0.0
102580852 ER membrane protein complex subunit 1 Solanum tuberosum
TI:4113 None
   
M4CPG8_BRACM
EnsemblPlants»
0.0
ER membrane protein complex subunit 1 Brassica campestris
TI:3711 None
   
M4CXK6_BRACM
EnsemblPlants»
0.0
ER membrane protein complex subunit 1 Brassica campestris
TI:3711 None
   
M4E3H8_BRACM
EnsemblPlants»
0.0
ER membrane protein complex subunit 1 Brassica campestris
TI:3711 None
   
Q4Q2C8_LEIMA
EnsemblProtists»
0.0
LMJF_34_4130 ER membrane protein complex subunit 1 Leishmania major
TI:5664 None
 
Q4WUQ2_ASPFU
EnsemblFungi»
0.0
AFUA_5G09270 ER membrane protein complex subunit 1 Aspergillus fumigatus
TI:746128 None
 
Q552B8_DICDI
dictyBase»
0.0
DDB_G0276243 ER membrane protein complex subunit 1 Dictyostelium discoideum
TI:44689 None
 
Q57ZY7_TRYB2
VEuPathDB»
0.0
Tb04.5E12.1170 ER membrane protein complex subunit 1 Trypanosoma brucei
TI:5691 None
 
Q5B402_EMENI
EnsemblFungi»
0.0
ANIA_04728 ER membrane protein complex subunit 1 Emericella nidulans
TI:162425 None
 
Q5KEQ0_CRYNJ
EnsemblFungi»
0.0
CNF04690 ER membrane protein complex subunit 1 Cryptococcus neoformans
TI:5207 None
 
Q5TT42_ANOGA
EnsemblMetazoa»
0.0
1274314 ER membrane protein complex subunit 1 Anopheles gambiae
TI:7165 None
 
Q6C5W6_YARLI
EnsemblFungi»
0.0
YALI0_E14575g ER membrane protein complex subunit 1 Yarrowia lipolytica
TI:4952 None
 
Q751V5_ASHGO
EnsemblFungi»
0.0
AGOS_AFR720W ER membrane protein complex subunit 1 Ashbya gossypii
TI:33169 None
 
Q75GB3_ORYSJ
EnsemblPlants»
0.0
Os05g0230600 ER membrane protein complex subunit 1 Oryza sativa
TI:4530 None
 
Q7SI37_NEUCR
EnsemblFungi»
0.0
NCU00614 ER membrane protein complex subunit 1 Neurospora crassa
TI:5141 None
 
Q8IAU7_PLAF7
EnsemblProtists»
0.0
PF3D7_0811200 ER membrane protein complex subunit 1 Plasmodium falciparum
TI:5833 None
 
Q9VHY6_DROME
FlyBase»
1.6
EMC1 ER membrane protein complex subunit 1 Drosophila melanogaster
TI:7227 None
 
T1G4P4_HELRO
EnsemblMetazoa»
0.0
20216042 ER membrane protein complex subunit 1 Helobdella robusta
TI:6412 None
 
W1NS17_AMBTC
EnsemblPlants»
0.0
AMTR_s00109p00121860 ER membrane protein complex subunit 1 Amborella trichopoda
TI:13333 None
 
W5MAJ0_LEPOC
Ensembl»
0.0
ER membrane protein complex subunit 1 Lepisosteus oculatus
TI:7918 None