Collated Gene Ontology terms

Biological process: acetyl-CoA carboxylase activity(2003, 2007, 2009, 2011, 2013, 2014, 2015, 2019, 2022, 2023, 2024) ATP binding(2004, 2011, 2013, 2024) ligase activity(2024) metal ion binding(2024) biotin carboxylase activity(2004, 2007, 2013, 2014, 2023, 2024) identical protein binding(2024) nucleotide binding(2024) biotin binding(2007, 2013, 2018, 2024) protein homodimerization activity(2016, 2024) propionyl-CoA carboxylase activity(2023, 2024)
carboxyl- or carbamoyltransferase activity2016, 2024 acetyl-CoA binding2016, 2024 sterol response element binding2013 signaling receptor binding2013 phosphatidylinositol-3,4,5-trisphosphate binding2018 nuclear thyroid hormone receptor binding2013 catalytic activity2024 DNA binding domain binding2013

Molecular function: fatty acid biosynthetic process2007, 2008, 2009, 2010, 2011, 2013, 2014, 2019, 2023, 2024 malonyl-CoA biosynthetic process2013, 2014, 2024 protein homotetramerization2011, 2024 acetyl-CoA metabolic process2011, 2024 lipid biosynthetic process2023, 2024 tissue homeostasis2009, 2024 response to nutrient levels2015, 2022, 2024 lipid metabolic process2009, 2024 lipid homeostasis2009, 2024 cellular response to prostaglandin E stimulus2014, 2024
regulation of glucose metabolic process2015, 2024 positive regulation of lipid storage2014, 2024 positive regulation of heart growth2014, 2024 negative regulation of lipid catabolic process2015, 2024 negative regulation of fatty acid oxidation2014, 2024 negative regulation of fatty acid beta-oxidation2015, 2024 energy homeostasis2015, 2024 small molecule metabolic process2024 response to xenobiotic stimulus2007, 2024 response to organic cyclic compound2007, 2024 response to nutrient2023, 2024 tricarboxylic acid metabolic process2023, 2024 regulation of cardiac muscle hypertrophy in response to stress2023, 2024 purine nucleotide metabolic process2023, 2024 protein import into nucleus2004, 2013, 2024 pentose-phosphate shunt2023, 2024 long-chain fatty acid biosynthetic process2013, 2019, 2024 lactic acid secretion2023, 2024 intracellular glutamate homeostasis2023, 2024 glucose import2023, 2024 fatty acid oxidation2023, 2024 fatty acid elongation2009, 2011 quorum sensing2012 mitotic nuclear membrane biogenesis2020, 2024 carboxylic acid metabolic process2024 acetyl-CoA biosynthetic process2016, 2024 triglyceride biosynthetic process2015 transport2013 shoot system development2005 root development2005 response to thyroid hormone2013 response to sucrose2015 response to insulin2013 response to fatty acid2013 response to cytokinin2005 response to carbohydrate2013 response to (R)-carnitine2018 regulation of biological quality2013 primary shoot apical meristem specification2009 positive regulation of gene expression2013 positive regulation of DNA-templated transcription2013 polarity specification of anterior/posterior axis2009 nematode larval development2009 negative regulation of gene expression2015 meristem structural organization2005 fatty-acyl-CoA biosynthetic process2024 epigenetic regulation of gene expression2013 embryo development ending in seed dormancy2005 cellular response to sucrose stimulus2015

Cellular component: mitochondrion2009, 2013, 2014, 2018, 2023, 2024 cytoplasm2009, 2011, 2013, 2018, 2024 cytosol2009, 2011, 2013, 2018, 2023, 2024 fibrillar center2023, 2024 actin cytoskeleton2023, 2024 nucleus2014, 2019, 2024 chloroplast2024 endoplasmic reticulum membrane2004, 2013, 2015, 2024 plastid2024 mitochondrial fatty acid beta-oxidation multienzyme complex2023, 2024
membrane2024 acetyl-CoA carboxylase complex2007, 2016, 2024 glycosome2017 mitochondrial outer membrane2022 fungal-type vacuole membrane2009 endoplasmic reticulum2024 apicoplast2014

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 2/4 
Harosa: 3/4 
Hacrobia: 0/0 
Plants: 37/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 5 10 15 Knownness

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Proteins

UniProt ID
Organism DB»
Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
ACAC_CHICK
CTD»
19.5
ACAC Acetyl-CoA carboxylase (ACC) (EC 6.4.1.2)
[Includes: Biotin carboxylase (EC 6.3.4.14)]
Gallus gallus
TI:9031 None
 
E9PSQ0_RAT
RGD»
18.9
Acacb acetyl-CoA carboxylase (EC 6.4.1.2) Rattus norvegicus
TI:10116 None
   
ACACA_RAT
RGD»
12.1
Acaca Acetyl-CoA carboxylase 1
(ACC1) (EC 6.4.1.2) (ACC-alpha)
Rattus norvegicus
TI:10116 None
 
ACACB_MOUSE
Ensembl»
10.1
Acacb Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) Mus musculus
TI:10090 None
 
ACACA_MOUSE
Ensembl»
9.6
Acaca Acetyl-CoA carboxylase 1 (ACC1) (EC
6.4.1.2) (ACC-alpha) (Acetyl-CoA carboxylase 265)
Mus musculus
TI:10090 None
 
ACAC_YEAST
SGD»
8.2
ACC1 Acetyl-CoA carboxylase (ACC) (EC 6.4.1.2) (Fatty acid synthetase 3)
(mRNA transport-defective protein 7) [Includes: Biotin carboxylase (EC 6.3.4.14)]
Saccharomyces cerevisiae
TI:4932 None
 
ACACA_HUMAN
Ensembl»
7.4
ACACA Acetyl-CoA carboxylase 1 (ACC1) (EC
6.4.1.2) (Acetyl-Coenzyme A carboxylase alpha) (ACC-alpha)
Homo sapiens
TI:9606 None
 
ACC1_ARATH
TAIR»
6.1
ACC1 Acetyl-CoA carboxylase 1 (AtACC1) (EC 6.4.1.2) (Protein EMBRYO DEFECTIVE 22)
(Protein GURKE) (Protein PASTICCINO 3) [Includes: Biotin carboxylase (EC 6.3.4.14)]
Arabidopsis thaliana
TI:3702 None
 
ACACB_HUMAN
Ensembl»
4.2
ACACB Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) Homo sapiens
TI:9606 None
 
A1Z784_DROME
FlyBase»
3.9
ACC acetyl-CoA carboxylase (EC 6.4.1.2) Drosophila melanogaster
TI:7227 None
 
H2L0M0_CAEEL
WormBase»
3.9
pod-2 acetyl-CoA carboxylase (EC 6.4.1.2) Caenorhabditis elegans
TI:6239 None
 
HFA1_YEAST
SGD»
3.1
HFA1 Acetyl-CoA carboxylase, mitochondrial (ACC) (EC
6.4.1.2) [Includes: Biotin carboxylase (EC 6.3.4.14)]
Saccharomyces cerevisiae
TI:4932 None
 
ACAC_DICDI
dictyBase»
3.0
accA Acetyl-CoA carboxylase (EC 6.4.1.2) (ACC-alpha)
[Includes: Biotin carboxylase (EC 6.3.4.14)]
Dictyostelium discoideum
TI:44689 None
 
ACAC_SCHPO
PomBase»
2.8
cut6 Acetyl-CoA carboxylase (ACC) (EC 6.4.1.2) (Cell untimely
torn protein 6) [Includes: Biotin carboxylase (EC 6.3.4.14)]
Schizosaccharomyces pombe
TI:4896 None
 
A0A8M9PK80_DANRE
CTD»
1.8
acaca acetyl-CoA carboxylase (EC 6.4.1.2) Danio rerio
TI:7955 None
   
A0A8M9PKW2_DANRE
CTD»
1.0
acacb acetyl-CoA carboxylase (EC 6.4.1.2) Danio rerio
TI:7955 None
   
Q9XUC3_CAEEL
WormBase»
1.0
CELE_T28F3.5 T28F3.5 acetyl-CoA carboxylase (EC 6.4.1.2) Caenorhabditis elegans
TI:6239 None
 
ACC2_ARATH
TAIR»
0.8
ACC2 Acetyl-CoA carboxylase 2 (EC 6.4.1.2)
[Includes: Biotin carboxylase (EC 6.3.4.14)]
Arabidopsis thaliana
TI:3702 None
 
A0A8M3APH6_DANRE
CTD»
0.0
LOC103909985 Acetyl-CoA carboxylase-like Danio rerio
TI:7955 None
   
A0A8V0ZIH3_CHICK
Ensembl»
0.0
ACACB acetyl-CoA carboxylase (EC 6.4.1.2) Gallus gallus
TI:9031 None
   
A0A8V1ACH3_CHICK
Ensembl»
0.0
ACACA acetyl-CoA carboxylase (EC 6.4.1.2) Gallus gallus
TI:9031 None