Collated Gene Ontology terms

Biological process: hydrolase activity(2024) serine-type endopeptidase activity(2024)

Molecular function: signal peptide processing2013, 2014, 2020, 2022, 2024 protein targeting to ER2013, 2017, 2024 viral protein processing2019, 2024 proteolysis2016, 2024 fat cell differentiation2013

Cellular component: signal peptidase complex2014, 2019, 2020, 2022, 2024 endoplasmic reticulum2009, 2010, 2013, 2018, 2021, 2024 endoplasmic reticulum membrane2009, 2013, 2020, 2022, 2024 membrane2024 organelle membrane2024 plasmodesma2021

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 4/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 38/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
SPC3_YEAST
SGD»
4.0
SPC3 Signal peptidase complex subunit 3
(Microsomal signal peptidase subunit 3)		 Saccharomyces cerevisiae
TI:4932 None
 
SPCS3_HUMAN
Ensembl»
3.4
SPCS3 Signal peptidase complex subunit 3 (Microsomal signal peptidase
22/23 kDa subunit) (SPC22/23) (SPase 22/23 kDa subunit)		 Homo sapiens
TI:9606 None
 
D3ZF12_RAT
RGD»
2.5
Spcs3 Signal peptidase complex subunit 3 Rattus norvegicus
TI:10116 None
   
SPCS3_RAT
RGD»
1.5
Spcs3 Signal peptidase complex subunit 3 (Microsomal signal peptidase
22/23 kDa subunit) (SPC22/23) (SPase 22/23 kDa subunit)		 Rattus norvegicus
TI:10116 None
 
SPC3_SCHPO
PomBase»
1.0
spc3 Signal peptidase complex subunit 3
(Microsomal signal peptidase subunit 3)		 Schizosaccharomyces pombe
TI:4896 None
 
Q6NWJ2_DANRE
ZFIN»
1.0
zgc:85675 Signal peptidase complex subunit 3 Danio rerio
TI:7955 None
 
SPCS3_CAEEL
WormBase»
1.0
spcs-3 Signal peptidase complex subunit 3 (Microsomal signal peptidase
22 kDa subunit) (SPC22) (SPase 22 kDa subunit)		 Caenorhabditis elegans
TI:6239 None
 
SPCS3_CHICK
Ensembl»
1.0
SPCS3 Signal peptidase complex subunit 3 (Microsomal signal peptidase
22/23 kDa subunit) (SPC22/23) (SPase 22/23 kDa subunit) (gp23)		 Gallus gallus
TI:9031 None
 
SPCS3_DICDI
dictyBase»
1.0
spcs3 Signal peptidase complex subunit 3 Dictyostelium discoideum
TI:44689 None
 
SPCS3_DROME
FlyBase»
1.0
Spase22-23 Signal peptidase complex subunit 3 (Microsomal signal peptidase
22 kDa subunit) (SPC22) (SPase 22 kDa subunit)		 Drosophila melanogaster
TI:7227 None
 
ARXS1_MOUSE
Ensembl»
0.8
Arxes1 Adipocyte-related X-chromosome
expressed sequence 1		 Mus musculus
TI:10090 None
 
ARXS2_MOUSE
Ensembl»
0.8
Arxes2 Adipocyte-related X-chromosome
expressed sequence 2		 Mus musculus
TI:10090 None
 
SPC3A_ARATH
TAIR»
0.0
At3g05230 Signal peptidase complex subunit 3A (Microsomal signal peptidase
22 kDa subunit) (SPC22) (SPase 22 kDa subunit)		 Arabidopsis thaliana
TI:3702 None
 
SPC3B_ARATH
TAIR»
0.0
At5g27430 Signal peptidase complex subunit 3B (Microsomal signal peptidase
22 kDa subunit) (SPC22) (SPase 22 kDa subunit)		 Arabidopsis thaliana
TI:3702 None
 
SPCS3_MOUSE
Ensembl»
0.0
Spcs3 Signal peptidase complex subunit 3 (Microsomal signal peptidase
22/23 kDa subunit) (SPC22/23) (SPase 22/23 kDa subunit)		 Mus musculus
TI:10090 None