Biological process: protein kinase activity^{(2003, 2005, 2006, 2008, 2010, 2012, 2013, 2014, 2015, 2016, 2017, 2018, 2020, 2023, 2024)} ATP binding^{(2003, 2009, 2014, 2024)} calmodulin-dependent protein kinase activity^{(2007, 2012, 2022, 2024)} calcium-dependent protein serine/threonine kinase activity^{(2013, 2021, 2022, 2024)} calmodulin binding^{(2009, 2012, 2024)} metal ion binding⁽²⁰²⁴⁾ calcium ion binding^{(2009, 2017, 2024)} kinase activity^{(2006, 2009, 2024)} protein serine/threonine kinase activity^{(2003, 2007, 2009, 2010, 2011, 2012, 2013, 2014, 2015, 2016, 2017, 2021, 2023, 2024)} histone H2AS1 kinase activity⁽²⁰²⁴⁾
± 30 protein serine kinase activity²⁰²⁴ mitogen-activated protein kinase binding^{2011, 2013, 2017, 2024} transferase activity²⁰²⁴ p53 binding^{2011, 2024} protein serine/threonine phosphatase activity^{2018, 2024} nucleic acid binding²⁰²⁴ zinc ion binding²⁰²⁴ protein phosphatase binding²⁰¹⁰ protein kinase binding^{2017, 2024} protein homodimerization activity²⁰¹⁵ microtubule binding²⁰¹⁵ lyase activity²⁰²⁴ cysteine-type deubiquitinase activity²⁰²⁴ MAP kinase kinase activity^{2003, 2005} ATP hydrolysis activity²⁰²⁴ ribosomal protein S6 kinase activity²⁰¹⁷ pseudouridine synthase activity²⁰²⁴ protein tyrosine kinase activity²⁰¹⁷ phosphoenolpyruvate carboxykinase (ATP) activity²⁰²⁴ myosin light chain kinase activity²⁰²⁴ glycosyltransferase activity²⁰²⁴ catalytic activity²⁰⁰⁹ calcium-dependent protein serine/threonine phosphatase activity²⁰⁰⁹ calcium-dependent protein kinase C activity²⁰⁰⁶ cGMP binding²⁰²⁴ acetylglucosaminyltransferase activity²⁰²⁴ RNA-DNA hybrid ribonuclease activity²⁰²⁴ RNA binding²⁰²⁴ ADP binding²⁰²⁴ 14-3-3 protein binding²⁰²¹

Molecular function: protein phosphorylation^{2003, 2005, 2006, 2007, 2009, 2010, 2011, 2014, 2017, 2018, 2020, 2021, 2024} intracellular signal transduction^{2003, 2020, 2023, 2024} phosphorylation²⁰²⁴ chromatin remodeling²⁰²⁴ response to cytokine^{2013, 2020, 2024} toll-like receptor signaling pathway^{2011, 2020, 2024} protein autophosphorylation^{2011, 2012, 2015, 2017, 2020, 2021, 2024} regulation of translation^{2011, 2024} peptidyl-serine phosphorylation^{2011, 2012, 2021, 2024} vascular endothelial growth factor receptor signaling pathway^{2020, 2024}
± 95 inflammatory response^{2011, 2020, 2024} response to lipopolysaccharide^{2011, 2024} macropinocytosis^{2011, 2024} cellular response to vascular endothelial growth factor stimulus^{2012, 2020, 2024} Ras protein signal transduction^{2011, 2020, 2024} negative regulation of TOR signaling^{2011, 2017, 2024} regulation of tumor necrosis factor production^{2011, 2024} abscisic acid-activated signaling pathway^{2005, 2006, 2012, 2024} regulation of interleukin-6 production^{2011, 2024} extrinsic apoptotic signaling pathway in absence of ligand^{2013, 2024} DNA damage response^{2011, 2024} positive regulation of tumor necrosis factor production^{2020, 2024} positive regulation of response to salt stress^{2017, 2024} positive regulation of macrophage cytokine production^{2020, 2024} p38MAPK cascade^{2015, 2024} mRNA stabilization^{2003, 2024} inner ear development^{2011, 2024} 3'-UTR-mediated mRNA stabilization^{2011, 2024} stress-induced premature senescence^{2011, 2024} defense response to fungus^{2017, 2024} response to cold^{2017, 2024} positive regulation of dendritic spine development^{2016, 2024} hemopoiesis^{2011, 2024} cellular response to arsenic-containing substance^{2011, 2024} positive regulation of transcription by RNA polymerase II²⁰²⁴ positive regulation of telomere maintenance²⁰²⁴ mitotic DNA damage checkpoint signaling²⁰²¹ behavioral response to nicotine^{2017, 2024} signal transduction^{2003, 2005, 2022, 2023} response to salt stress^{2006, 2010, 2012, 2013, 2024} response to water deprivation^{2017, 2024} regulation of pollen tube growth^{2010, 2013, 2024} response to osmotic stress^{2017, 2024} response to abscisic acid^{2017, 2024} positive regulation of response to water deprivation^{2017, 2024} pollen maturation^{2017, 2024} nodulation^{2016, 2024} negative regulation of response to salt stress^{2017, 2024} leaf senescence^{2012, 2024} cellular response to abscisic acid stimulus^{2012, 2024} regulation of stomatal movement^{2006, 2024} regulation of secondary shoot formation^{2017, 2024} regulation of presynapse assembly^{2017, 2024} regulation of leaf senescence²⁰²⁰ regulation of inward rectifier potassium channel activity^{2013, 2024} regulation of anion channel activity^{2007, 2024} negative regulation of defense response to bacterium^{2017, 2024} defense response²⁰²⁴ apoptotic process²⁰²⁴ MAPK cascade^{2003, 2024} response to light stimulus²⁰¹⁰ response to cycloheximide²⁰¹⁰ response to calcium ion²⁰²¹ regulation of axon extension involved in axon guidance^{2017, 2024} regulation of 3'-UTR-mediated mRNA stabilization^{2017, 2024} positive regulation of regulated secretory pathway²⁰²¹ positive regulation of axon extension involved in regeneration^{2017, 2024} positive regulation of abscisic acid-activated signaling pathway²⁰⁰⁸ positive regulation of 3'-UTR-mediated mRNA stabilization^{2017, 2024} epiboly involved in gastrulation with mouth forming second^{2009, 2024} determination of adult lifespan²⁰¹⁷ chromosome segregation²⁰¹⁴ cell differentiation²⁰²⁴ adult locomotory behavior^{2017, 2024} response to salicylic acid²⁰⁰⁶ response to other organism²⁰²⁴ response to bacterium²⁰²¹ regulation of tumor necrosis factor-mediated signaling pathway²⁰²⁴ regulation of translational initiation²⁰¹⁴ regulation of stomatal opening²⁰¹³ regulation of signal transduction by p53 class mediator²⁰²⁴ regulation of sarcomere organization²⁰¹⁷ regulation of protein deneddylation²⁰¹² regulation of mRNA stability²⁰²⁴ regulation of growth²⁰⁰⁶ regulation of cellular response to heat²⁰²⁴ regulation of JNK cascade²⁰¹² pseudouridine synthesis²⁰²⁴ proteolysis²⁰¹⁸ protein glycosylation²⁰²⁴ post-transcriptional regulation of gene expression²⁰¹⁶ positive regulation of telomere maintenance via telomerase²⁰¹⁵ positive regulation of telomere capping²⁰¹⁵ positive regulation of gibberellic acid mediated signaling pathway²⁰¹⁷ positive regulation of cell size²⁰¹¹ positive regulation of DNA-templated transcription²⁰²⁰ peptidyl-threonine phosphorylation²⁰²¹ negative regulation of mitochondrial electron transport, NADH to ubiquinone²⁰²⁴ microtubule-based process²⁰⁰⁶ male gamete generation²⁰²¹ leukotriene metabolic process²⁰²⁴ heat acclimation²⁰¹² cellular senescence²⁰²⁴ cellular response to phosphate starvation²⁰¹⁰ cell surface receptor signaling pathway²⁰⁰⁵

Cellular component: cytoplasm^{2009, 2010, 2011, 2013, 2015, 2017, 2018, 2021, 2022, 2023, 2024} nucleus^{2003, 2006, 2010, 2011, 2012, 2013, 2015, 2020, 2021, 2022, 2023, 2024} plasma membrane^{2010, 2011, 2013, 2017, 2019, 2021, 2024} membrane^{2003, 2009, 2010, 2021, 2024} nucleoplasm^{2013, 2015, 2022, 2023, 2024} cytosol^{2011, 2013, 2015, 2017, 2019, 2023, 2024} centrosome^{2006, 2023, 2024} protein-containing complex^{2018, 2021, 2024} septin cytoskeleton^{2016, 2024} nuclear body^{2023, 2024}
± 29 synapse^{2010, 2024} plasmodesma²⁰²¹ PML body²⁰²⁴ A band^{2015, 2024} symbiont-containing vacuole membrane^{2021, 2024} peroxisome^{2004, 2024} peroxisomal membrane^{2017, 2024} mitochondrion²⁰¹⁹ microneme membrane^{2021, 2024} kinetochore²⁰¹⁴ host cell plasma membrane^{2021, 2024} endoplasmic reticulum membrane^{2003, 2024} symbiont-containing vacuolar space²⁰²⁰ sarcomere²⁰²⁴ plastid²⁰¹⁹ plant-type vacuole²⁰²¹ perikaryon²⁰²⁴ nuclear lumen²⁰¹⁷ nuclear envelope²⁰⁰⁶ motile cilium²⁰²⁴ microtubule²⁰⁰⁶ extrinsic component of membrane²⁰²¹ extrinsic component of cytoplasmic side of plasma membrane²⁰²¹ extracellular exosome²⁰¹⁴ endoplasmic reticulum²⁰²⁴ cytoplasmic vesicle²⁰²⁴ ciliary plasm²⁰¹⁷ axoneme²⁰¹⁷ Golgi membrane²⁰²⁴