Collated Gene Ontology terms

Biological process: aminoacylase activity(2003, 2006, 2021, 2025) hydrolase activity(2025) metal ion binding(2025) identical protein binding(2025) formylmethionine deformylase activity(2025) metalloendopeptidase activity(2025) ATP-dependent peptidase activity(2025) ATP binding(2025)

Molecular function: amino acid metabolic process2025 protein catabolic process2006, 2025 response to zinc ion2010 proteolysis2025

Cellular component: cytoplasm2018, 2025 extracellular exosome2014, 2025 endoplasmic reticulum2021 nucleus2019 chloroplast2018 secretory vesicle2019 plasma membrane2019 plant-type vacuole2021 membrane2025 cytosol2025
Golgi apparatus2021

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 0/1 
Porifera: 0/0 
Choanoflagellates+: 2/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 38/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
A0A8V1AGV2_CHICK
Ensembl»
0.5
ACY1 N-acyl-aliphatic-L-amino acid amidohydrolase
(EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase)		 Gallus gallus
TI:9031 None
   
ACY1_HUMAN
Ensembl»
3.0
ACY1 Aminoacylase-1 (ACY-1) (EC
3.5.1.14) (N-acyl-L-amino-acid amidohydrolase)		 Homo sapiens
TI:9606 None
 
F4JTK8_ARATH
TAIR»
1.3
AQI N-acyl-aliphatic-L-amino acid amidohydrolase
(EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase)		 Arabidopsis thaliana
TI:3702 None
 
ACY1_MOUSE
AG»
1.5
Acy1 Aminoacylase-1 (ACY-1) (EC
3.5.1.14) (N-acyl-L-amino-acid amidohydrolase)		 Mus musculus
TI:10090 None
 
ACY1A_RAT
RGD»
3.2
Acy1a Aminoacylase-1A (ACY-1A) (EC 3.5.1.14) (ACY
IA) (N-acyl-L-amino-acid amidohydrolase) (f-Met deformylase) (fMDF)		 Rattus norvegicus
TI:10116 None
 
Q9LPE9_ARATH
TAIR»
0.5
At1g44820 At1g44820 (Peptidase M20/M25/M40
family protein) (T12C22.9 protein)		 Arabidopsis thaliana
TI:3702 None
 
Q5WRS4_CAEEL
WormBase»
0.5
C06A6.4 CELE_C06A6.4 N-acyl-aliphatic-L-amino acid amidohydrolase
(EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase)		 Caenorhabditis elegans
TI:6239 None
 
Q17898_CAEEL
WormBase»
0.5
C10C5.3 CELE_C10C5.3 N-acyl-aliphatic-L-amino acid amidohydrolase
(EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase)		 Caenorhabditis elegans
TI:6239 None
 
Q17899_CAEEL
WormBase»
0.5
C10C5.4 CELE_C10C5.4 N-acyl-aliphatic-L-amino acid amidohydrolase
(EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase)		 Caenorhabditis elegans
TI:6239 None
 
Q17900_CAEEL
WormBase»
0.5
C10C5.5 CELE_C10C5.5 N-acyl-aliphatic-L-amino acid amidohydrolase
(EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase)		 Caenorhabditis elegans
TI:6239 None
 
Q9VCR0_DROME
FlyBase»
0.5
Dmel\CG17109 N-acyl-aliphatic-L-amino acid amidohydrolase
(EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase)		 Drosophila melanogaster
TI:7227 None
 
Q8T490_DROME
FlyBase»
0.5
Dmel\CG17110 N-acyl-aliphatic-L-amino acid amidohydrolase
(EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase)		 Drosophila melanogaster
TI:7227 None
 
Q9I7K3_DROME
FlyBase»
0.5
Dmel\CG6465 N-acyl-aliphatic-L-amino acid amidohydrolase
(EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase)		 Drosophila melanogaster
TI:7227 None
 
Q9VCR2_DROME
FlyBase»
0.5
Dmel\CG6726 N-acyl-aliphatic-L-amino acid amidohydrolase
(EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase)		 Drosophila melanogaster
TI:7227 None
 
Q9VCQ9_DROME
FlyBase»
0.5
Dmel\CG6733 N-acyl-aliphatic-L-amino acid amidohydrolase
(EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase)		 Drosophila melanogaster
TI:7227 None
 
Q9VCQ8_DROME
FlyBase»
0.5
Dmel\CG6738 N-acyl-aliphatic-L-amino acid amidohydrolase
(EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase)		 Drosophila melanogaster
TI:7227 None
 
Q9C6Y8_ARATH
TAIR»
0.5
T18F15.13 Aminoacylase, putative (Peptidase
M20/M25/M40 family protein)		 Arabidopsis thaliana
TI:3702 None
 
ACY1_DICDI
dictyBase»
0.5
acy1 Aminoacylase-1 (ACY-1) (EC
3.5.1.14) (N-acyl-L-amino-acid amidohydrolase)		 Dictyostelium discoideum
TI:44689 None