Collated Gene Ontology terms

Biological process: RNA binding(2025) DNA binding(2025) identical protein binding(2025)

Molecular function: mRNA export from nucleus2012, 2013, 2017, 2024, 2025 signal transduction2025 mRNA transport2025 mRNA processing2025 apoptotic process2005, 2025 RNA splicing2025 DNA-templated transcription2025 regulatory ncRNA-mediated gene silencing2010, 2025 regulation of apoptotic process2005, 2021 ta-siRNA processing2010
poly(A)+ mRNA export from nucleus2023 piRNA processing2024 mRNA export from nucleus in response to heat stress2011 ethylene-activated signaling pathway2016 defense response to fungus2012 defense response2025

Cellular component: THO complex part of transcription export complex2005, 2009, 2017, 2025 nucleus2005, 2009, 2011, 2016, 2018, 2025 THO complex2009, 2011, 2013, 2014, 2025 nucleoplasm2015, 2025 nuclear matrix2025 cytoplasm2009, 2025 transcription export complex2009, 2016, 2025 nuclear speck2025 cytosol2025 chromosome, telomeric region2016, 2025
protein-containing complex2011

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 11/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 3/4 
Hacrobia: 0/0 
Plants: 36/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
W1PQL0_AMBTC
neXtProt»
0.0
AMTR_s00029p00122290 THO complex subunit 1 Amborella trichopoda
TI:13333 None
 
A0A803TIZ2_ANOCA
Ensembl»
0.0
Caspase recruitment domain family member 8 Anolis carolinensis
TI:28377 None
   
G1KHP8_ANOCA
Ensembl»
0.0
THOC1 THO complex subunit 1
(Nuclear matrix protein p84)		 Anolis carolinensis
TI:28377 None
   
Q7QH59_ANOGA
EnsemblMetazoa»
0.0
1270873 AGAP004070-PA Anopheles gambiae
TI:7165 None
 
THOC1_ARATH
TAIR»
4.5
THO1 THO complex subunit 1
(AtTHO1) (HPR1 homolog) (AtHPR1)		 Arabidopsis thaliana
TI:3702 None
 
Q4W9N3_ASPFU
TubercuList»
0.0
AFUA_4G04330 THO complex subunit Tho1, putative Aspergillus fumigatus
TI:746128 None
 
F4P1Q2_BATDJ
neXtProt»
0.0
BATDEDRAFT_24368 THO complex subunit 1 Batrachochytrium dendrobatidis
TI:109871 None
 
F1MJV3_BOVIN
Ensembl»
0.0
THOC1 THO complex subunit 1
(Nuclear matrix protein p84)		 Bos taurus
TI:9913 None
   
I1HAN7_BRADI
EnsemblPlants»
0.0
LOC100832078 THO complex subunit 1 Brachypodium distachyon
TI:15368 None
 
A0A9J7HXK1_BRAFL
euHCVdb»
0.0
LOC118409014 THO complex subunit 1-like Branchiostoma floridae
TI:7739 None 		     
A0A9J7KMH8_BRAFL
euHCVdb»
0.0
LOC118409655 THO complex subunit 1-like Branchiostoma floridae
TI:7739 None
   
A0A078HS09_BRANA
euHCVdb»
0.0
BnaC02g00660D BnaC02g00660D protein Brassica napus
TI:3708 None
 
M4EIJ8_BRACM
EnsemblPlants»
0.0
THO complex subunit 1 Brassica campestris
TI:3711 None
   
A8WK85_CAEBR
WormBase»
0.0
thoc-1 Protein CBR-THOC-1 Caenorhabditis briggsae
TI:6238 None
 
Q9N5E3_CAEEL
WormBase»
0.5
thoc-1 Death domain-containing protein Caenorhabditis elegans
TI:6239 None
 
A0A8I3ML03_CANLF
Ensembl»
0.0
THOC1 THO complex subunit 1
(Nuclear matrix protein p84)		 Canis lupus
TI:9612 None
   
A0A8I3Q180_CANLF
Ensembl»
0.0
LOC102153616 Caspase recruitment domain family member 8 Canis lupus
TI:9612 None
   
A0A2G2YYN0_CAPAN
euHCVdb»
0.0
T459_22110 THO complex subunit 1 Capsicum annuum
TI:4072 None
 
A0A2K3CS86_CHLRE
euHCVdb»
0.0
CHLRE_16g695300v5 THO complex subunit 1 Chlamydomonas reinhardtii
TI:3055 None
 
A0A2K3CSB0_CHLRE
euHCVdb»
0.0
CHLRE_16g695400v5 Uncharacterized protein Chlamydomonas reinhardtii
TI:3055 None
 
F6T7M7_CIOIN
Ensembl»
0.0
THO complex subunit 1 Ciona intestinalis
TI:7719 None
 
A0A067D3N0_CITSI
neXtProt»
0.0
CISIN_1g032647mg Uncharacterized protein Citrus sinensis
TI:2711 None 		 
 
A0A067DDE1_CITSI
euHCVdb»
0.0
CISIN_1g048387mg Uncharacterized protein Citrus sinensis
TI:2711 None 		 
 
Q5KDN0_CRYD1
TubercuList»
0.0
CNG03370 THO complex subunit 1 Cryptococcus deneoformans
TI:40410 None
 
A0A0A0KTL0_CUCSA
euHCVdb»
0.0
Csa_5G407100 THO complex subunit 1 Cucumis sativus
TI:3659 None
 
E7FGV0_DANRE
ZFIN»
0.0
si:dkeyp-97b10.3 NACHT, LRR and PYD domains-containing protein
1a allele 5 isoform X1 (Si:dkeyp-97b10.3)		 Danio rerio
TI:7955 None
 
THOC1_DANRE
ZFIN»
1.3
thoc1 THO complex subunit 1 Danio rerio
TI:7955 None
 
E9GZL5_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_226474 Death domain-containing protein Daphnia pulex
TI:6669 None
 
F0ZDE5_DICPU
TubercuList»
0.0
DICPUDRAFT_29296 THO complex subunit 1 Dictyostelium purpureum
TI:5786 None
 
Q552T7_DICDI
dictyBase»
0.5
thoc1 THO complex subunit 1 Dictyostelium discoideum
TI:44689 None
 
Q9VNI8_DROME
FlyBase»
2.5
Hpr1 Hpr1 (LD43883p) Drosophila melanogaster
TI:7227 None
 
Q5AXG7_EMENI
TubercuList»
0.0
ANIA_07013 THO complex subunit
Tho1, putative (AFU_orthologue AFUA_4G04330)		 Emericella nidulans
TI:162425 None
 
A0A9L0RM43_HORSE
Ensembl»
0.0
THOC1 THO complex subunit 1
(Nuclear matrix protein p84)		 Equus caballus
TI:9796 None
   
A0A9L0T1L7_HORSE
Ensembl»
0.0
LOC102148661 Caspase recruitment domain family member 8 Equus caballus
TI:9796 None
   
A0A022QHB1_ERYGU
euHCVdb»
0.0
MIMGU_mgv1a003005mg THO complex subunit 1 Erythranthe guttata
TI:4155 None
 
A0ABI7WM26_FELCA
Ensembl»
0.0
THOC1 Death domain-containing protein Felis catus
TI:9685 None
   
A0ABI7WW84_FELCA
Ensembl»
0.0
OSER1 FIIND domain-containing protein Felis catus
TI:9685 None
   
A0A8V0X9S0_CHICK
Ensembl»
0.5
NLRP1L Caspase recruitment domain-containing protein 8 Gallus gallus
TI:9031 None
   
A0A8V0XIW7_CHICK
Ensembl»
0.0
THOC1 THO complex subunit 1
(Nuclear matrix protein p84)		 Gallus gallus
TI:9031 None
   
A0A0R4J354_SOYBN
EnsemblPlants»
0.0
LOC100781333 THO complex subunit 1 Glycine max
TI:3847 None
 
G3QKJ3_GORGO
Ensembl»
0.0
THO complex subunit 1
(Nuclear matrix protein p84)		 Gorilla gorilla
TI:9593 None
 
A0A1U8II69_GOSHI
neXtProt»
0.0
LOC107897015 THO complex subunit 1 isoform X1 Gossypium hirsutum
TI:3635 None
   
A0A1U8LL70_GOSHI
neXtProt»
0.0
LOC107927603 THO complex subunit 1 isoform X1 Gossypium hirsutum
TI:3635 None
   
A0A251VGI2_HELAN
euHCVdb»
0.0
AtTHO1 Putative nuclear matrix protein
(THO complex, subunit THOC1 protein)		 Helianthus annuus
TI:4232 None
 
T1G4B6_HELRO
EnsemblMetazoa»
0.0
20215914 Death domain-containing protein Helobdella robusta
TI:6412 None
 
THOC1_HUMAN
Ensembl»
2.7
THOC1 THO complex subunit 1 (Nuclear
matrix protein p84) (p84N5) (hTREX84)		 Homo sapiens
TI:9606 None
 
A0A8I6XLY0_HORVV
EnsemblPlants»
0.0
LOC123450042 THO complex subunit 1 Hordeum vulgare
TI:4513 None
   
B7PCI2_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW016836 Nuclear matrix protein, putative Ixodes scapularis
TI:6945 None
 
A0A2I4EX28_JUGRE
euHCVdb»
0.0
LOC108993471 THO complex subunit 1 Juglans regia
TI:51240 None
   
A0A1Y1IDZ9_KLENI
euHCVdb»
0.0
KFL_004950040 Putative THO complex subunit THOC1 Klebsormidium nitens
TI:105231 None
 
A0A9R1V7N0_LACSA
euHCVdb»
0.0
LSAT_V11C600301770 THO complex subunit 1 Lactuca sativa
TI:4236 None
 
W5M264_LEPOC
Ensembl»
0.0
THO complex 1 Lepisosteus oculatus
TI:7918 None
 
W5M7Q2_LEPOC
Ensembl»
0.0
Si:dkeyp-97b10.3 Lepisosteus oculatus
TI:7918 None
 
G7NKF9_MACMU
Ensembl»
0.0
THOC1 THO complex subunit 1
(Nuclear matrix protein p84)		 Macaca mulatta
TI:9544 None
 
A0A2C9W510_MANES
euHCVdb»
0.0
MANES_04G156400v8 THO complex subunit 1 Manihot esculenta
TI:3983 None
 
A0A2R6XNE1_MARPO
euHCVdb»
0.0
MARPO_0007s0076 THO complex subunit 1 Marchantia polymorpha
TI:3197 None
 
A0A5F8GFY3_MONDO
Ensembl»
0.0
THOC1 THO complex subunit 1
(Nuclear matrix protein p84)		 Monodelphis domestica
TI:13616 None
   
THOC1_MOUSE
Ensembl»
3.2
Thoc1 THO complex subunit 1
(Nuclear matrix protein p84)		 Mus musculus
TI:10090 None
 
A0A804HY45_MUSAM
EnsemblPlants»
0.0
THO complex subunit 1 Musa acuminata
TI:4641 None
   
A0A1U8AFQ0_NELNU
euHCVdb»
0.0
LOC104603927 THO complex subunit 1-like Nelumbo nucifera
TI:4432 None
   
A0A1U8AYD2_NELNU
neXtProt»
0.0
LOC104607737 THO complex subunit 1-like Nelumbo nucifera
TI:4432 None
   
A7SY90_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g219410 THO complex subunit 1 Nematostella vectensis
TI:45351 None 		 
 
Q7SBU4_NEUCR
TubercuList»
0.0
NCU07865 THO complex subunit Tho1 Neurospora crassa
TI:5141 None
 
A0A6I8PMQ3_ORNAN
Ensembl»
0.0
CARD8 Caspase recruitment domain family member 8 Ornithorhynchus anatinus
TI:9258 None
   
F6UYH4_ORNAN
Ensembl»
0.0
THOC1 THO complex subunit 1
(Nuclear matrix protein p84)		 Ornithorhynchus anatinus
TI:9258 None
   
Q10SU9_ORYSJ
neXtProt»
0.0
LOC_Os03g01970 Os03g0110400 Os03g0110400 protein (THO complex
subunit 1, putative, expressed)		 Oryza sativa
TI:4530 None
 
A0A3B3I7H4_ORYLA
Ensembl»
0.0
Si:dkeyp-97b10.3 Oryzias latipes
TI:8090 None
   
H2MTF7_ORYLA
Ensembl»
0.0
THOC1 THO complex 1 Oryzias latipes
TI:8090 None
   
H2QE64_PANTR
Ensembl»
0.0
THOC1 THO complex subunit 1
(Nuclear matrix protein p84)		 Pan troglodytes
TI:9598 None
 
A0CLL7_PARTE
euHCVdb»
0.0
GSPATT00008233001 THO complex subunitTHOC2
C-terminal domain-containing protein		 Paramecium tetraurelia
TI:5888 None
 
A0CZW1_PARTE
euHCVdb»
0.0
GSPATT00011901001 THO complex subunitTHOC2
C-terminal domain-containing protein		 Paramecium tetraurelia
TI:5888 None
 
A0A7U2EXD9_PHANO
TubercuList»
0.0
JI435_082380 Nuclear matrix protein Phaeosphaeria nodorum
TI:13684 None 		 
 
A0A2K1L077_PHYPA
EnsemblPlants»
0.0
LOC112278897 THO complex subunit 1 Physcomitrium patens
TI:3218 None
 
H3GQT3_PHYRM
EnsemblProtists»
0.0
THO complex subunit 1 Phytophthora ramorum
TI:164328 None
 
A0A2K2B9K6_POPTR
euHCVdb»
0.0
POPTR_003G194000 THO complex subunit 1 Populus trichocarpa
TI:3694 None
 
B9GLX5_POPTR
neXtProt»
0.0
POPTR_001G031700 THO complex subunit 1 Populus trichocarpa
TI:3694 None
 
A0A251N4J9_PRUPE
neXtProt»
0.0
PRUPE_7G006200 THO complex subunit 1 Prunus persica
TI:3760 None
 
E3KCW5_PUCGT
TubercuList»
0.0
PGTG_07648 THO complex subunit 1 Puccinia graminis
TI:5297 None
 
THOC1_RAT
RGD»
0.5
Thoc1 THO complex subunit 1 (Liver regeneration-related
protein LRRG175) (Nuclear matrix protein p84)		 Rattus norvegicus
TI:10116 None
 
B9SVG7_RICCO
neXtProt»
0.0
RCOM_1264550 Nuclear matrix protein, putative Ricinus communis
TI:3988 None
 
B6K5Y9_SCHJY
TubercuList»
0.0
tho1 THO complex subunit Schizosaccharomyces japonicus
TI:4897 None
 
YJU3_SCHPO
PomBase»
1.5
SPCP25A2.03 Uncharacterized protein P25A2.03 Schizosaccharomyces pombe
TI:4896 None
 
A7E5T9_SCLS1
TubercuList»
0.0
SS1G_00664 Uncharacterized protein Sclerotinia sclerotiorum
TI:5180 None
 
D8RMU7_SELML
euHCVdb»
0.0
SELMODRAFT_96989 THO complex subunit 1 Selaginella moellendorffii
TI:88036 None
 
D8TAD7_SELML
neXtProt»
0.0
SELMODRAFT_135550 THO complex subunit 1 Selaginella moellendorffii
TI:88036 None
 
K4A6Y7_SETIT
EnsemblPlants»
0.0
LOC101786851 THO complex subunit 1 Setaria italica
TI:4555 None
 
A0A3Q7EM37_SOLLC
EnsemblPlants»
0.0
THO complex subunit 1 Solanum lycopersicum
TI:4081 None
   
A0A1Z5SBX6_SORBI
euHCVdb»
0.0
SORBI_3001G536400 THO complex subunit 1 Sorghum bicolor
TI:4558 None
 
A0A9R0HRL6_SPIOL
neXtProt»
0.0
LOC110774872 THO complex subunit 1 Spinacia oleracea
TI:3562 None
   
A0A7M7NNS4_STRPU
EnsemblMetazoa»
0.0
Death domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A4X1VPA4_PIG
Ensembl»
0.0
THOC1 THO complex subunit 1
(Nuclear matrix protein p84)		 Sus scrofa
TI:9823 None
   
B8CBS0_THAPS
euHCVdb»
0.0
THAPSDRAFT_9591 THO complex subunit 1 Thalassiosira pseudonana
TI:35128 None
 
A0A061FRX0_THECC
neXtProt»
0.0
TCM_044779 Nuclear matrix protein-related isoform 1 Theobroma cacao
TI:3641 None
 
D6WX23_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_06470 THO complex subunit 1-like Protein Tribolium castaneum
TI:7070 None
 
B3RQ95_TRIAD
CTD»
0.0
TRIADDRAFT_53823 Death domain-containing protein Trichoplax adhaerens
TI:10228 None
 
B3SB40_TRIAD
CTD»
0.0
TRIADDRAFT_1612 THO complex subunit 1 Trichoplax adhaerens
TI:10228 None
 
A0A3B6J0I7_WHEAT
EnsemblPlants»
0.0
LOC123094024 THO complex subunit 1 Triticum aestivum
TI:4565 None
   
A0A3B6KUZ1_WHEAT
EnsemblPlants»
0.0
LOC123106180 THO complex subunit 1 Triticum aestivum
TI:4565 None
   
A0A3B6LN96_WHEAT
EnsemblPlants»
0.0
THO complex subunit 1 Triticum aestivum
TI:4565 None
   
A0A3B6UB75_WHEAT
EnsemblPlants»
0.0
LOC123099218 THO complex subunit 1 Triticum aestivum
TI:4565 None
   
D7TX68_VITVI
euHCVdb»
0.0
VIT_13s0084g00520 THO complex subunit 1 Vitis vinifera
TI:29760 None
 
F6HVB5_VITVI
neXtProt»
0.0
VIT_13s0084g00370 THO complex subunit 1 Vitis vinifera
TI:29760 None
 
F6XN58_XENTR
Xenbase»
0.0
thoc1 THO complex 1 protein (THO complex subunit 1) Xenopus tropicalis
TI:8364 None
   
Q498H9_XENLA
Xenbase»
0.0
thoc1.L LOC398505 protein (THO complex
1 protein L homeolog)		 Xenopus laevis
TI:8355 None
 
Q6CB86_YARLI
TubercuList»
0.0
YALI0_C21131g YALI0C21131p Yarrowia lipolytica
TI:4952 None
 
C0HE46_MAIZE
EnsemblPlants»
0.0
LOC100304252 THO complex subunit 1 Zea mays
TI:4577 None
 
A0A0K9PMZ1_ZOSMR
euHCVdb»
0.0
ZOSMA_19G00200 THO complex subunit 1 Zostera marina
TI:29655 None