Collated Gene Ontology terms

Biological process: translation initiation factor activity(2014, 2025) mRNA binding(2025) ribosomal small subunit binding(2016) peptidyl-prolyl cis-trans isomerase activity(2025) mRNA 5'-UTR binding(2019) isomerase activity(2025) RNA binding(2022)

Molecular function: formation of translation preinitiation complex2014, 2017, 2025 translational initiation2014, 2025 translation reinitiation2017, 2019, 2025 cytoplasmic translational initiation2025 translation2025 regulation of translation2025 ribosome disassembly2014, 2022, 2025 IRES-dependent viral translational initiation2017, 2025 positive regulation of insulin receptor signaling pathway2023 positive regulation of ecdysone receptor signaling pathway2023
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay2024

Cellular component: cytoplasm2018, 2022, 2024, 2025 ribosome2025 ribonucleoprotein complex2025 protein-containing complex2016 cytosol2015

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 15/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 3/4 
Harosa: 4/4 
Hacrobia: 0/0 
Plants: 38/39 
Archea: 6/8 
Bacteria: 12/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
Q8VZK2_ARATH
TAIR»
1.0
At5g11900 Translation machinery-associated protein 22 Arabidopsis thaliana
TI:3702 None
 
DENR_CAEEL
WormBase»
1.0
Y47D3A.21 Density-regulated protein homolog Caenorhabditis elegans
TI:6239 None
 
DENR_DANRE
ZFIN»
1.0
denr Density-regulated protein (DRP) Danio rerio
TI:7955 None
 
DENR_DICDI
dictyBase»
1.0
denr Density-regulated protein homolog Dictyostelium discoideum
TI:44689 None
 
DENR_DROME
FlyBase»
4.2
DENR Density-regulated protein homolog Drosophila melanogaster
TI:7227 None
 
YCIH_ECOLI
EnsemblBacteria»
1.8
yciH Uncharacterized protein YciH Escherichia coli
TI:562 None
 
DENR_CHICK
Ensembl»
1.0
DENR Density-regulated protein (DRP) Gallus gallus
TI:9031 None
 
DENR_HUMAN
Ensembl»
3.4
DENR Density-regulated protein (DRP) (Protein DRP1)
(Smooth muscle cell-associated protein 3) (SMAP-3)		 Homo sapiens
TI:9606 None
 
DENR_MOUSE
Ensembl»
2.5
Denr Density-regulated protein (DRP) Mus musculus
TI:10090 None
 
D3ZU54_RAT
RGD»
2.5
Denr Density-regulated protein Rattus norvegicus
TI:10116 None
   
DENR_YEAST
SGD»
3.1
TMA22 Translation machinery-associated protein
22 (Density-regulated protein homolog)		 Saccharomyces cerevisiae
TI:4932 None
 
DENR_SCHPO
PomBase»
1.0
tma22 Translation machinery-associated protein
22 (Density-regulated protein homolog)		 Schizosaccharomyces pombe
TI:4896 None