Collated Gene Ontology terms

Biological process: RNA binding(2017, 2025) RNA helicase activity(2025) translation initiation factor activity(2023, 2025) nucleotide binding(2025) nucleic acid binding(2025) hydrolase activity(2025) helicase activity(2025) ATP binding(2025) mRNA binding(2025) ubiquitin binding(2017)

Molecular function: mRNA export from nucleus2009, 2021, 2024, 2025 protein ubiquitination2010, 2024, 2025 negative regulation of abscisic acid-activated signaling pathway2010, 2025 mRNA transport2025 mRNA processing2025 RNA splicing2025 apoptotic process2025 central nervous system development2013, 2025 translational initiation2025 translation2025
transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery2017 ta-siRNA processing2010 regulatory ncRNA-mediated gene silencing2010 piRNA processing2024 mRNA export from nucleus in response to heat stress2016 cytoplasmic translational initiation2023 abscisic acid-activated signaling pathway2025 RNA export from nucleus2020

Cellular component: THO complex2009, 2011, 2014, 2022, 2025 transcription export complex2009, 2016, 2021, 2025 nucleus2010, 2013, 2025 nuclear speck2024, 2025 Cul4-RING E3 ubiquitin ligase complex2008, 2025 nucleoplasm2015, 2024, 2025 chromosome, telomeric region2016, 2025 THO complex part of transcription export complex2009, 2025 nuclear pore2025 nuclear body2025
mitochondrion2019 cytoplasmic stress granule2023 cytoplasm2018

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 34/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
THOC6_ARATH
TAIR»
3.7
THO6 THO complex subunit 6 (AtTHO6) (Protein DWD
HYPERSENSITIVE TO ABA 1) (WD repeat-containing protein DWA1)		 Arabidopsis thaliana
TI:3702 None
 
THOC6_HUMAN
Ensembl»
2.7
THOC6 THO complex subunit 6 (Functional spliceosome-associated
protein 35) (fSAP35) (WD repeat-containing protein 58)		 Homo sapiens
TI:9606 None
 
THOC6_DROME
FlyBase»
2.7
thoc6 THO complex subunit 6 Drosophila melanogaster
TI:7227 None
 
THOC6_MOUSE
Ensembl»
2.0
Thoc6 THO complex subunit 6
homolog (WD repeat-containing protein 58)		 Mus musculus
TI:10090 None
 
Q54K59_DICDI
dictyBase»
0.5
thoc6 WD40 repeat-containing protein Dictyostelium discoideum
TI:44689 None
 
THOC6_DANRE
ZFIN»
0.5
thoc6 THO complex subunit 6
homolog (WD repeat-containing protein 58)		 Danio rerio
TI:7955 None
 
THOC6_RAT
RGD»
2.0
Thoc6 THO complex subunit 6
homolog (WD repeat-containing protein 58)		 Rattus norvegicus
TI:10116 None
 
A0A8V0XD98_CHICK
Ensembl»
0.0
LOC121108727 THO complex 6 Gallus gallus
TI:9031 None