Collated Gene Ontology terms

Biological process:

Molecular function: response to retinoic acid2009, 2024 positive regulation of DNA repair2009, 2024 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage2013, 2024 cellular response to oxidative stress2009, 2024 cellular response to UV2009, 2024 regulation of heart rate2021, 2024 regulation of cardiac muscle cell action potential2021, 2024 regulation of cardiac muscle contraction by calcium ion signaling2023 positive regulation of endoplasmic reticulum calcium ion concentration2020

Cellular component: membrane2024 plasma membrane2021, 2024 endoplasmic reticulum2020

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 34/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
U5D9Y7_AMBTC
EnsemblPlants»
0.0
AMTR_s00069p00069960 Transmembrane protein Amborella trichopoda
TI:13333 None
 
G1K8K9_ANOCA
Ensembl»
0.0
TMEM161B Transmembrane protein 161B Anolis carolinensis
TI:28377 None
   
Q7PPG5_ANOGA
EnsemblMetazoa»
0.0
1275757 AGAP004945-PA Anopheles gambiae
TI:7165 None
 
Q9LTK2_ARATH
TAIR»
0.0
At5g52180 Dbj|BAA83359.1 (Transmembrane protein 161AB
protein) (Uncharacterized protein At5g52180)		 Arabidopsis thaliana
TI:3702 None
 
A0A3Q1M0M5_BOVIN
Ensembl»
0.0
TMEM161A Transmembrane protein 161A Bos taurus
TI:9913 None
   
E1BKP1_BOVIN
Ensembl»
0.0
TMEM161B Transmembrane protein 161B Bos taurus
TI:9913 None
   
I1H162_BRADI
EnsemblPlants»
0.0
100821264 Uncharacterized protein Brachypodium distachyon
TI:15368 None
 
A0A9J7KW42_BRAFL
CTD»
0.0
LOC118412248 LOW QUALITY PROTEIN:
transmembrane protein 161B-like		 Branchiostoma floridae
TI:7739 None
   
A0A078GZN5_BRANA
EnsemblPlants»
0.0
BnaC09g28290D BnaC09g28290D protein Brassica napus
TI:3708 None
 
M4DNV1_BRACM
EnsemblPlants»
0.0
CSC1/OSCA1-like 7TM
region domain-containing protein		 Brassica campestris
TI:3711 None
   
M4EHN1_BRACM
EnsemblPlants»
0.0
Transmembrane protein 161A/B Brassica campestris
TI:3711 None
   
A8XWB9_CAEBR
WormBase»
0.0
CBG19780 CBG_19780 Protein CBG19780 Caenorhabditis briggsae
TI:6238 None
 
Q9U1P9_CAEEL
WormBase»
0.0
CELE_Y87G2A.13 Y87G2A.13 Lysosomal cobalamin transporter Caenorhabditis elegans
TI:6239 None
 
A0A8I3NWM6_CANLF
Ensembl»
0.0
TMEM161A Transmembrane protein 161A Canis lupus
TI:9612 None
   
A0A8I3P0C5_CANLF
Ensembl»
0.0
TMEM161B Transmembrane protein 161B Canis lupus
TI:9612 None
   
A0A2G2ZZ10_CAPAN
EnsemblPlants»
0.0
T459_09314 Transmembrane protein 161B Capsicum annuum
TI:4072 None
 
A0A2K3CT71_CHLRE
EnsemblPlants»
0.0
CHLRE_16g656050v5 Uncharacterized protein Chlamydomonas reinhardtii
TI:3055 None
 
F6WRB6_CIOIN
Ensembl»
0.0
LOC100185206 Transmembrane protein 161B Ciona intestinalis
TI:7719 None
   
A0A067FA12_CITSI
Ensembl»
0.0
CISIN_1g040232mg Transmembrane protein 163 Citrus sinensis
TI:2711 None
 
A0A0A0L8M8_CUCSA
EnsemblPlants»
0.0
Csa_3G181950 Transmembrane protein 161B Cucumis sativus
TI:3659 None
 
T161A_DANRE
ZFIN»
0.0
tmem161a Transmembrane protein 161A Danio rerio
TI:7955 None
 
T161B_DANRE
ZFIN»
2.4
tmem161b Transmembrane protein 161B Danio rerio
TI:7955 None
 
E9G1H4_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_312768 EOG090X04CK Daphnia pulex
TI:6669 None
 
Q9VTF5_DROME
FlyBase»
0.8
emei Emei (RE42071p) Drosophila melanogaster
TI:7227 None
 
F6Q677_HORSE
Ensembl»
0.0
TMEM161B Transmembrane protein 161B Equus caballus
TI:9796 None
   
F6ZXN1_HORSE
Ensembl»
0.0
TMEM161A Transmembrane protein 161A Equus caballus
TI:9796 None
   
A0A022PZ90_ERYGU
EnsemblFungi»
0.0
MIMGU_mgv1a026972mg Transmembrane protein Erythranthe guttata
TI:4155 None
 
A0A337S3L9_FELCA
Ensembl»
0.0
TMEM161B Transmembrane protein 161B Felis catus
TI:9685 None
 
M3WC34_FELCA
Ensembl»
0.0
TMEM161A Transmembrane protein 161A Felis catus
TI:9685 None
 
A0A8V0XRU2_CHICK
Ensembl»
0.0
TMEM161B Transmembrane protein 161B Gallus gallus
TI:9031 None
   
A0A8V1AJG8_CHICK
Ensembl»
0.0
TMEM161A Transmembrane protein 161A Gallus gallus
TI:9031 None
   
A0A0R0I5D3_SOYBN
EnsemblPlants»
0.0
GLYMA_10G237700 Transmembrane protein 161B Glycine max
TI:3847 None
 
C6TJ73_SOYBN
EnsemblPlants»
0.0
100786159 Transmembrane protein 161B Glycine max
TI:3847 None
 
A0A2I2YTK3_GORGO
Ensembl»
0.0
Transmembrane protein 161B Gorilla gorilla
TI:9593 None
 
G3QSD4_GORGO
Ensembl»
0.0
TMEM161B Transmembrane protein 161B Gorilla gorilla
TI:9593 None
 
G3S558_GORGO
Ensembl»
0.0
TMEM161A Transmembrane protein 161A Gorilla gorilla
TI:9593 None
 
A0A1U8NHT5_GOSHI
Ensembl»
0.0
LOC107947298 Uncharacterized protein LOC107947298 isoform X1 Gossypium hirsutum
TI:3635 None
   
A0A251TW60_HELAN
EnsemblPlants»
0.0
HannXRQ_Chr09g0253731 HanXRQr2_Chr09g0385261 Transmembrane protein 161B Helianthus annuus
TI:4232 None
 
T1FXF1_HELRO
EnsemblMetazoa»
0.0
20213499 Transmembrane protein 161B Helobdella robusta
TI:6412 None
 
T161A_HUMAN
Ensembl»
4.0
TMEM161A Transmembrane protein 161A (Adaptive response
to oxidative stress protein 29) (AROS-29)		 Homo sapiens
TI:9606 None
 
T161B_HUMAN
Ensembl»
1.0
TMEM161B Transmembrane protein 161B Homo sapiens
TI:9606 None
 
A0A8I6Y818_HORVV
EnsemblPlants»
0.0
Uncharacterized protein Hordeum vulgare
TI:4513 None
   
B7PF81_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW004783 Uncharacterized protein Ixodes scapularis
TI:6945 None
 
B7QD30_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW013257 Transmembrane protein 161B, putative Ixodes scapularis
TI:6945 None
 
A0A2I4FGD7_JUGRE
EnsemblPlants»
0.0
LOC108998590 Uncharacterized protein LOC108998590 Juglans regia
TI:51240 None
 
W5M1B2_LEPOC
Ensembl»
0.0
Transmembrane protein 161B Lepisosteus oculatus
TI:7918 None
 
W5MBP3_LEPOC
Ensembl»
0.0
Transmembrane protein 161A Lepisosteus oculatus
TI:7918 None
 
A0A1D5QZA5_MACMU
Ensembl»
0.0
Transmembrane protein 161B Macaca mulatta
TI:9544 None
   
A0A1D5R7J6_MACMU
Ensembl»
0.0
TMEM161A Transmembrane protein 161A Macaca mulatta
TI:9544 None
   
F7HLT5_MACMU
Ensembl»
0.0
TMEM161B Transmembrane protein 161B Macaca mulatta
TI:9544 None
   
A0A2C9UIF9_MANES
EnsemblPlants»
0.0
MANES_14G027600 Transmembrane protein 161B Manihot esculenta
TI:3983 None
 
A0A2C9VSX8_MANES
EnsemblPlants»
0.0
MANES_06G145800 Transmembrane protein 161B Manihot esculenta
TI:3983 None
 
A0A2R6WSD4_MARPO
EnsemblPlants»
0.0
MARPO_0061s0021 Uncharacterized protein Marchantia polymorpha
TI:3197 None
 
A0A072W093_MEDTR
EnsemblPlants»
0.0
25485092 Transmembrane protein 161AB, putative Medicago truncatula
TI:3880 None
 
A0A5F8G4M2_MONDO
Ensembl»
0.0
TMEM161B Transmembrane protein 161B Monodelphis domestica
TI:13616 None
   
F6VW04_MONDO
Ensembl»
0.0
TMEM161A Transmembrane protein 161A Monodelphis domestica
TI:13616 None
   
A9V6B3_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_27787 Uncharacterized protein Monosiga brevicollis
TI:81824 None
 
T161A_MOUSE
Ensembl»
0.0
Tmem161a Transmembrane protein 161A Mus musculus
TI:10090 None
 
T161B_MOUSE
Ensembl»
1.6
Tmem161b Transmembrane protein 161B Mus musculus
TI:10090 None
 
A0A804HPR7_MUSAM
EnsemblPlants»
0.0
GSMUA_287050.1 (wild Malaysian banana) hypothetical protein Musa acuminata
TI:4641 None
 
A0A1U8BB86_NELNU
EnsemblBacteria»
0.0
LOC104612737 Transmembrane protein 161B Nelumbo nucifera
TI:4432 None
 
A7SGV4_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g117848 Transmembrane protein 161B Nematostella vectensis
TI:45351 None
 
A0A1S4BHA2_TOBAC
EnsemblFungi»
0.0
LOC107808260 Uncharacterized protein LOC107808260 Nicotiana tabacum
TI:4097 None
   
A0A1S4CWF2_TOBAC
EnsemblFungi»
0.0
LOC107823243 Uncharacterized protein LOC107823243 Nicotiana tabacum
TI:4097 None
   
F7A2B1_ORNAN
Ensembl»
0.0
TMEM161A Transmembrane protein 161A Ornithorhynchus anatinus
TI:9258 None
   
F7FD58_ORNAN
Ensembl»
0.0
TMEM161B Transmembrane protein 161B Ornithorhynchus anatinus
TI:9258 None
   
Q658H9_ORYSJ
EnsemblPlants»
0.0
Os06g0129000 Os06g0129000 protein Oryza sativa
TI:4530 None
 
A0A3B3HEH6_ORYLA
Ensembl»
0.0
tmem161a Transmembrane protein 161A Oryzias latipes
TI:8090 None
   
H2M2F6_ORYLA
Ensembl»
0.0
tmem161b Transmembrane protein 161B Oryzias latipes
TI:8090 None
   
H2R692_PANTR
Ensembl»
0.0
TMEM161A Transmembrane protein 161A Pan troglodytes
TI:9598 None
 
K6ZYH1_PANTR
Ensembl»
0.0
TMEM161B Transmembrane protein 161B Pan troglodytes
TI:9598 None
 
H3GI97_PHYRM
EnsemblProtists»
0.0
Transmembrane protein Phytophthora ramorum
TI:164328 None
 
B9ID55_POPTR
EnsemblPlants»
0.0
POPTR_015G140900 Transmembrane protein 161B Populus trichocarpa
TI:3694 None
 
A0A8R1U719_PRIPA
EnsemblMetazoa»
0.0
WBGene00098810 G protein-coupled receptor Pristionchus pacificus
TI:54126 None
   
M5X6H5_PRUPE
EnsemblPlants»
0.0
PRUPE_2G292200 Transmembrane protein 161B Prunus persica
TI:3760 None
 
A0A8I5Y238_RAT
RGD»
1.0
Tmem161b Transmembrane protein 161B Rattus norvegicus
TI:10116 None
   
A0A8I5ZYV8_RAT
RGD»
0.0
ENSRNOG00000067374 Transmembrane protein 161B Rattus norvegicus
TI:10116 None
   
A0A8I6G628_RAT
RGD»
0.0
LOC685655 Similar to CG7638-PA Rattus norvegicus
TI:10116 None
   
F7EZW5_RAT
RGD»
2.5
Tmem161a Transmembrane protein 161A Rattus norvegicus
TI:10116 None
   
B9R9E0_RICCO
EnsemblBacteria»
0.0
RCOM_1496630 Uncharacterized protein Ricinus communis
TI:3988 None
 
D8RFC8_SELML
EnsemblPlants»
0.0
SELMODRAFT_440915 Uncharacterized protein Selaginella moellendorffii
TI:88036 None
 
D8SDH2_SELML
EnsemblPlants»
0.0
SELMODRAFT_420900 Uncharacterized protein Selaginella moellendorffii
TI:88036 None
 
D8SDH3_SELML
EnsemblPlants»
0.0
SELMODRAFT_420901 CSC1/OSCA1-like 7TM
region domain-containing protein		 Selaginella moellendorffii
TI:88036 None
 
D8SDI2_SELML
EnsemblPlants»
0.0
SELMODRAFT_420909 Uncharacterized protein Selaginella moellendorffii
TI:88036 None
 
A0A3Q7FHH8_SOLLC
EnsemblPlants»
0.0
Uncharacterized protein Solanum lycopersicum
TI:4081 None
   
M1B4W7_SOLTU
EnsemblPlants»
0.0
102578897 Transmembrane protein Solanum tuberosum
TI:4113 None
   
A0A194YGW1_SORBI
EnsemblPlants»
0.0
SORBI_3010G018500 GPI mannosyltransferase 2 Sorghum bicolor
TI:4558 None
 
A0A7M7MZT0_STRPU
EnsemblMetazoa»
0.0
Transmembrane protein 161B Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7RG26_STRPU
EnsemblMetazoa»
0.0
Transmembrane protein 161B Strongylocentrotus purpuratus
TI:7668 None
   
A0A287AKT1_PIG
Ensembl»
0.0
TMEM161A Transmembrane protein 161A Sus scrofa
TI:9823 None
   
A0A480QDK0_PIG
Ensembl»
0.0
TMEM161B Transmembrane protein 161B (Transmembrane
protein 161B isoform 2)		 Sus scrofa
TI:9823 None
 
A0A061G7W6_THECC
EnsemblPlants»
0.0
TCM_015120 Transmembrane protein Theobroma cacao
TI:3641 None
 
A0A139WAU9_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_31638 Transmembrane protein 161B-like Protein Tribolium castaneum
TI:7070 None
 
B3RHZ3_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_20008 Gustatory receptor Trichoplax adhaerens
TI:10228 None
 
A0A3B6R8F2_WHEAT
EnsemblPlants»
0.0
CFC21_095576 Uncharacterized protein Triticum aestivum
TI:4565 None
 
F6HP51_VITVI
EnsemblPlants»
0.0
VIT_16s0100g00730 Transmembrane protein 161B Vitis vinifera
TI:29760 None
 
A0A8J0U2K5_XENLA
CTD»
0.0
LOC108707238 Transmembrane protein 161B isoform X1 Xenopus laevis
TI:8355 None
   
A0A8J0VF30_XENLA
CTD»
0.0
LOC108717489 Transmembrane protein 161B Xenopus laevis
TI:8355 None
   
F7CXQ2_XENTR
Xenbase»
0.0
tmem161b Transmembrane protein 161B Xenopus tropicalis
TI:8364 None
   
T161A_XENLA
Xenbase»
0.0
tmem161a Transmembrane protein 161A Xenopus laevis
TI:8355 None
 
T161A_XENTR
Xenbase»
0.0
tmem161 Transmembrane protein 161A Xenopus tropicalis
TI:8364 None
 
K7VSV5_MAIZE
EnsemblPlants»
0.0
ZEAMMB73_Zm00001d045496 GPI mannosyltransferase 2 Zea mays
TI:4577 None
 
A0A0K9NXP6_ZOSMR
EnsemblPlants»
0.0
ZOSMA_57G00360 Transmembrane protein Zostera marina
TI:29655 None